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Aliases for ZNF614 Gene

Aliases for ZNF614 Gene

  • Zinc Finger Protein 614 2 3

External Ids for ZNF614 Gene

Previous GeneCards Identifiers for ZNF614 Gene

  • GC19M057208
  • GC19M057209
  • GC19M057210
  • GC19M057211
  • GC19M057212
  • GC19M057213
  • GC19M057214
  • GC19M057215
  • GC19M052516
  • GC19M048847

Summaries for ZNF614 Gene

GeneCards Summary for ZNF614 Gene

ZNF614 (Zinc Finger Protein 614) is a Protein Coding gene. Among its related pathways are Gene Expression and Gene Expression. An important paralog of this gene is ZNF182.

UniProtKB/Swiss-Prot for ZNF614 Gene

  • May be involved in transcriptional regulation

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF614 Gene

Genomics for ZNF614 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for ZNF614 Gene

52,012,765 bp from pter
52,030,240 bp from pter
17,476 bases
Minus strand

Genomic View for ZNF614 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZNF614 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF614 Gene

No data available for Regulatory Elements for ZNF614 Gene

Proteins for ZNF614 Gene

  • Protein details for ZNF614 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Zinc finger protein 614
    Protein Accession:
    Secondary Accessions:
    • Q494T8
    • Q8TCF4
    • Q9BSN8

    Protein attributes for ZNF614 Gene

    585 amino acids
    Molecular mass:
    67215 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ZNF614 Gene


neXtProt entry for ZNF614 Gene

Proteomics data for ZNF614 Gene at MOPED

Post-translational modifications for ZNF614 Gene

  • Ubiquitination at Lys509
  • Modification sites at PhosphoSitePlus

Other Protein References for ZNF614 Gene

ENSEMBL proteins:
Reactome Protein details:
REFSEQ proteins:

No data available for DME Specific Peptides for ZNF614 Gene

Domains for ZNF614 Gene

Gene Families for ZNF614 Gene

  • ZNF :Zinc fingers, C2H2-type

Protein Domains for ZNF614 Gene

Suggested Antigen Peptide Sequences for ZNF614 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Q8N883
  • Contains 1 KRAB domain.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 12 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF614: view

Function for ZNF614 Gene

Molecular function for ZNF614 Gene

UniProtKB/Swiss-Prot Function: May be involved in transcriptional regulation

Gene Ontology (GO) - Molecular Function for ZNF614 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003674 molecular_function ND --
GO:0003676 nucleic acid binding --
GO:0003677 DNA binding IEA --
GO:0005515 protein binding IPI 22458338
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF614: view

Phenotypes for ZNF614 Gene

GenomeRNAi human phenotypes for ZNF614:
genes like me logo Genes that share phenotypes with ZNF614: view

Animal Model Products

CRISPR Products

miRNA for ZNF614 Gene

miRTarBase miRNAs that target ZNF614

No data available for Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for ZNF614 Gene

Localization for ZNF614 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF614 Gene

Subcellular locations from

Jensen Localization Image for ZNF614 Gene COMPARTMENTS Subcellular localization image for ZNF614 gene
Compartment Confidence
nucleus 4
cytosol 2

Gene Ontology (GO) - Cellular Components for ZNF614 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005575 cellular_component ND --
GO:0005622 intracellular --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF614: view

Pathways for ZNF614 Gene

SuperPathways for ZNF614 Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF614: view

Pathways by source for ZNF614 Gene

2 Reactome pathways for ZNF614 Gene

Gene Ontology (GO) - Biological Process for ZNF614 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
GO:0008150 biological_process ND --
genes like me logo Genes that share ontologies with ZNF614: view

Transcripts for ZNF614 Gene

mRNA/cDNA for ZNF614 Gene

Unigene Clusters for ZNF614 Gene

Zinc finger protein 614:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZNF614

Primer Products

  • OriGene qSTAR qPCR primer pairs in human,mouse,rat for ZNF614
  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF614 Gene

ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4a · 4b ^ 5a · 5b ^ 6a · 6b · 6c · 6d ^ 7
SP1: - - - -
SP2: - -
SP3: - - - -

Relevant External Links for ZNF614 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ZNF614 Gene

mRNA expression in normal human tissues for ZNF614 Gene

SOURCE GeneReport for Unigene cluster for ZNF614 Gene Hs.292336

genes like me logo Genes that share expressions with ZNF614: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein expression and mRNA Expression by UniProt/SwissProt for ZNF614 Gene

Orthologs for ZNF614 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF614 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia ZNF614 35
  • 99.66 (n)
  • 99.49 (a)
ZNF614 36
  • 99 (a)
(Bos Taurus)
Mammalia ZNF614 35
  • 82.02 (n)
  • 74.61 (a)
ZNF614 36
  • 74 (a)
(Canis familiaris)
Mammalia ZNF614 36
  • 77 (a)
(Monodelphis domestica)
Mammalia -- 36
  • 41 (a)
-- 36
  • 45 (a)
-- 36
  • 37 (a)
-- 36
  • 38 (a)
-- 36
  • 36 (a)
-- 36
  • 39 (a)
-- 36
  • 39 (a)
-- 36
  • 35 (a)
-- 36
  • 38 (a)
-- 36
  • 38 (a)
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 37 (a)
Species with no ortholog for ZNF614:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF614 Gene

Gene Tree for ZNF614 (if available)
Gene Tree for ZNF614 (if available)

Paralogs for ZNF614 Gene

Selected SIMAP similar genes for ZNF614 Gene using alignment to 4 proteins: Pseudogenes for ZNF614 Gene

genes like me logo Genes that share paralogs with ZNF614: view

Variants for ZNF614 Gene

Sequence variations from dbSNP and Humsavar for ZNF614 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type MAF
rs2288884 -- 52,029,018(-) AACAT(A/G)TAGAT upstream-variant-2KB
rs3217389 -- 52,029,707(-) TGAAC(-/TTA)TTATA upstream-variant-2KB
rs3840908 -- 52,028,350(-) TTACC(-/C)GCTCA utr-variant-5-prime
rs4313899 -- 52,023,453(+) TTCAA(A/G)AGTTT intron-variant
rs4802891 -- 52,024,505(+) agatc(A/C)gactg intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF614 Gene

Variant ID Type Subtype PubMed ID
esv638 CNV CNV 17122850
dgv143e55 CNV Gain 17911159
dgv1112e1 CNV Complex 17122850
dgv425n27 CNV Gain 19166990
dgv1113e1 CNV Complex 17122850
nsv833872 CNV Loss 17160897

Relevant External Links for ZNF614 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF614 Gene

Disorders for ZNF614 Gene

No disorders were found for ZNF614 Gene.

No data available for UniProtKB/Swiss-Prot for ZNF614 Gene

Publications for ZNF614 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  4. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  5. Host-pathogen interactome mapping for HTLV-1 and -2 retroviruses. (PMID: 22458338) Simonis N. … Twizere J.C. (Retrovirology 2012) 3

Products for ZNF614 Gene

Sources for ZNF614 Gene

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