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Aliases for ZNF614 Gene

Aliases for ZNF614 Gene

  • Zinc Finger Protein 614 2 3

External Ids for ZNF614 Gene

Summaries for ZNF614 Gene

GeneCards Summary for ZNF614 Gene

ZNF614 (Zinc Finger Protein 614) is a Protein Coding gene. Among its related pathways are Gene Expression and Gene Expression. An important paralog of this gene is ZNF182.

UniProtKB/Swiss-Prot for ZNF614 Gene

  • May be involved in transcriptional regulation

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF614 Gene

Genomics for ZNF614 Gene

Genomic Location for ZNF614 Gene

Start:
52,012,765 bp from pter
End:
52,030,240 bp from pter
Size:
17,476 bases
Orientation:
Minus strand

Genomic View for ZNF614 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZNF614 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF614 Gene

No data available for Regulatory Elements for ZNF614 Gene

Proteins for ZNF614 Gene

  • Protein details for ZNF614 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8N883-ZN614_HUMAN
    Recommended name:
    Zinc finger protein 614
    Protein Accession:
    Q8N883
    Secondary Accessions:
    • Q494T8
    • Q8TCF4
    • Q9BSN8

    Protein attributes for ZNF614 Gene

    Size:
    585 amino acids
    Molecular mass:
    67215 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ZNF614 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZNF614 Gene

Proteomics data for ZNF614 Gene at MOPED

Post-translational modifications for ZNF614 Gene

  • Modification sites at PhosphoSitePlus
  • Ubiquitination at Lys509

Other Protein References for ZNF614 Gene

ENSEMBL proteins:
Reactome Protein details:
REFSEQ proteins:

No data available for DME Specific Peptides for ZNF614 Gene

Domains for ZNF614 Gene

Gene Families for ZNF614 Gene

HGNC:
  • ZNF :Zinc fingers, C2H2-type

Protein Domains for ZNF614 Gene

UniProtKB/Swiss-Prot:

ZN614_HUMAN
Domain:
  • Contains 1 KRAB domain.:
    • Q8N883
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.:
    • Q8N883
Similarity:
  • Contains 12 C2H2-type zinc fingers.:
    • Q8N883
genes like me logo Genes that share domains with ZNF614: view

Function for ZNF614 Gene

Molecular function for ZNF614 Gene

UniProtKB/Swiss-Prot Function: May be involved in transcriptional regulation

Gene Ontology (GO) - Molecular Function for ZNF614 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003674 molecular_function ND --
GO:0003676 nucleic acid binding --
GO:0003677 DNA binding IEA --
GO:0005515 protein binding IPI 22458338
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF614: view

Phenotypes for ZNF614 Gene

GenomeRNAi human phenotypes for ZNF614:
genes like me logo Genes that share phenotypes with ZNF614: view

miRNA for ZNF614 Gene

miRTarBase miRNAs that target ZNF614

No data available for Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for ZNF614 Gene

Localization for ZNF614 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF614 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF614 Gene COMPARTMENTS Subcellular localization image for ZNF614 gene
Compartment Confidence
nucleus 4
cytosol 2

Gene Ontology (GO) - Cellular Components for ZNF614 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005575 cellular_component ND --
GO:0005622 intracellular --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF614: view

Pathways for ZNF614 Gene

SuperPathways for ZNF614 Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF614: view

Pathways by source for ZNF614 Gene

2 Reactome pathways for ZNF614 Gene

Gene Ontology (GO) - Biological Process for ZNF614 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
GO:0008150 biological_process ND --
genes like me logo Genes that share ontologies with ZNF614: view

Transcripts for ZNF614 Gene

Unigene Clusters for ZNF614 Gene

Zinc finger protein 614:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF614 Gene

ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4a · 4b ^ 5a · 5b ^ 6a · 6b · 6c · 6d ^ 7
SP1: - - - -
SP2: - -
SP3: - - - -
SP4:

Relevant External Links for ZNF614 Gene

GeneLoc Exon Structure for
ZNF614
ECgene alternative splicing isoforms for
ZNF614

Expression for ZNF614 Gene

mRNA expression in normal human tissues for ZNF614 Gene

SOURCE GeneReport for Unigene cluster for ZNF614 Gene Hs.292336

genes like me logo Genes that share expressions with ZNF614: view

Orthologs for ZNF614 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF614 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF614 36
  • 99.66 (n)
  • 99.49 (a)
ZNF614 37
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia ZNF614 36
  • 82.02 (n)
  • 74.61 (a)
ZNF614 37
  • 74 (a)
OneToOne
dog
(Canis familiaris)
Mammalia ZNF614 37
  • 77 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia -- 37
  • 41 (a)
ManyToMany
-- 37
  • 45 (a)
ManyToMany
-- 37
  • 37 (a)
ManyToMany
-- 37
  • 38 (a)
ManyToMany
-- 37
  • 36 (a)
ManyToMany
-- 37
  • 39 (a)
ManyToMany
-- 37
  • 39 (a)
ManyToMany
-- 37
  • 35 (a)
ManyToMany
-- 37
  • 38 (a)
ManyToMany
-- 37
  • 38 (a)
ManyToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 37
  • 37 (a)
OneToMany
Species with no ortholog for ZNF614:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF614 Gene

ENSEMBL:
Gene Tree for ZNF614 (if available)
TreeFam:
Gene Tree for ZNF614 (if available)

Paralogs for ZNF614 Gene

Selected SIMAP similar genes for ZNF614 Gene using alignment to 4 proteins:

Pseudogenes.org Pseudogenes for ZNF614 Gene

genes like me logo Genes that share paralogs with ZNF614: view

Variants for ZNF614 Gene

Sequence variations from dbSNP and Humsavar for ZNF614 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type MAF
rs2288884 -- 52,029,018(-) AACAT(A/G)TAGAT upstream-variant-2KB
rs3217389 -- 52,029,707(-) TGAAC(-/TTA)TTATA upstream-variant-2KB
rs3840908 -- 52,028,350(-) TTACC(-/C)GCTCA utr-variant-5-prime
rs4313899 -- 52,023,453(+) TTCAA(A/G)AGTTT intron-variant
rs4802891 -- 52,024,505(+) agatc(A/C)gactg intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF614 Gene

Variant ID Type Subtype PubMed ID
esv638 CNV CNV 17122850
dgv143e55 CNV Gain 17911159
dgv1112e1 CNV Complex 17122850
dgv425n27 CNV Gain 19166990
dgv1113e1 CNV Complex 17122850
nsv833872 CNV Loss 17160897

Relevant External Links for ZNF614 Gene

HapMap Linkage Disequilibrium report
ZNF614

Disorders for ZNF614 Gene

No disorders were found for ZNF614 Gene.

No data available for UniProtKB/Swiss-Prot for ZNF614 Gene

Publications for ZNF614 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  4. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  5. Host-pathogen interactome mapping for HTLV-1 and -2 retroviruses. (PMID: 22458338) Simonis N. … Twizere J.C. (Retrovirology 2012) 3

Products for ZNF614 Gene

Sources for ZNF614 Gene

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