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Aliases for ZNF613 Gene

Aliases for ZNF613 Gene

  • Zinc Finger Protein 613 2 3 5

External Ids for ZNF613 Gene

Previous GeneCards Identifiers for ZNF613 Gene

  • GC19P057123
  • GC19P057125
  • GC19P052430
  • GC19P048761

Summaries for ZNF613 Gene

GeneCards Summary for ZNF613 Gene

ZNF613 (Zinc Finger Protein 613) is a Protein Coding gene. Among its related pathways are Gene Expression. GO annotations related to this gene include nucleic acid binding. An important paralog of this gene is ZNF615.

UniProtKB/Swiss-Prot for ZNF613 Gene

  • May be involved in transcriptional regulation.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF613 Gene

Genomics for ZNF613 Gene

Regulatory Elements for ZNF613 Gene

Enhancers for ZNF613 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around ZNF613 on UCSC Golden Path with GeneCards custom track

Transcription factor binding sites by QIAGEN in the ZNF613 gene promoter:

Genomic Location for ZNF613 Gene

Chromosome:
19
Start:
51,879,872 bp from pter
End:
51,948,759 bp from pter
Size:
68,888 bases
Orientation:
Plus strand

Genomic View for ZNF613 Gene

Genes around ZNF613 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF613 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF613 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF613 Gene

Proteins for ZNF613 Gene

  • Protein details for ZNF613 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6PF04-ZN613_HUMAN
    Recommended name:
    Zinc finger protein 613
    Protein Accession:
    Q6PF04
    Secondary Accessions:
    • Q96SS9

    Protein attributes for ZNF613 Gene

    Size:
    617 amino acids
    Molecular mass:
    70143 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ZNF613 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZNF613 Gene

Proteomics data for ZNF613 Gene at MOPED

Post-translational modifications for ZNF613 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF613 Gene

No data available for DME Specific Peptides for ZNF613 Gene

Domains & Families for ZNF613 Gene

Gene Families for ZNF613 Gene

Protein Domains for ZNF613 Gene

Suggested Antigen Peptide Sequences for ZNF613 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q6PF04

UniProtKB/Swiss-Prot:

ZN613_HUMAN :
  • Contains 1 KRAB domain.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 12 C2H2-type zinc fingers.
Domain:
  • Contains 1 KRAB domain.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 12 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF613: view

Function for ZNF613 Gene

Molecular function for ZNF613 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Gene Ontology (GO) - Molecular Function for ZNF613 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding IEA --
GO:0044212 transcription regulatory region DNA binding IBA --
genes like me logo Genes that share ontologies with ZNF613: view
genes like me logo Genes that share phenotypes with ZNF613: view

Animal Model Products

CRISPR Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF613 Gene

Localization for ZNF613 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF613 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF613 Gene COMPARTMENTS Subcellular localization image for ZNF613 gene
Compartment Confidence
nucleus 5
cytosol 2

No data available for Gene Ontology (GO) - Cellular Components for ZNF613 Gene

Pathways & Interactions for ZNF613 Gene

SuperPathways for ZNF613 Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF613: view

Pathways by source for ZNF613 Gene

2 Reactome pathways for ZNF613 Gene

Interacting Proteins for ZNF613 Gene

Gene Ontology (GO) - Biological Process for ZNF613 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000122 negative regulation of transcription from RNA polymerase II promoter IBA --
GO:0045944 positive regulation of transcription from RNA polymerase II promoter IBA --
genes like me logo Genes that share ontologies with ZNF613: view

No data available for SIGNOR curated interactions for ZNF613 Gene

Drugs & Compounds for ZNF613 Gene

No Compound Related Data Available

Transcripts for ZNF613 Gene

Unigene Clusters for ZNF613 Gene

Zinc finger protein 613:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF613 Gene

ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3a · 3b ^ 4a · 4b · 4c ^ 5a · 5b ^ 6a · 6b ^ 7 ^ 8a · 8b · 8c · 8d
SP1: - - - -
SP2: - -
SP3: - - - -
SP4: - - - - -
SP5: - - - -
SP6: - -
SP7: - - - -
SP8:
SP9: - - - - - -

Relevant External Links for ZNF613 Gene

GeneLoc Exon Structure for
ZNF613
ECgene alternative splicing isoforms for
ZNF613

Expression for ZNF613 Gene

mRNA expression in normal human tissues for ZNF613 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

SOURCE GeneReport for Unigene cluster for ZNF613 Gene Hs.183390

genes like me logo Genes that share expression patterns with ZNF613: view

Primer Products

No data available for mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for ZNF613 Gene

Orthologs for ZNF613 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF613 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia ZNF613 35
  • 82.36 (n)
  • 75.32 (a)
ZNF613 36
  • 72 (a)
OneToOne
dog
(Canis familiaris)
Mammalia ZNF613 35
  • 84.36 (n)
  • 78.83 (a)
ZNF613 36
  • 74 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Zfp157 35
  • 59.86 (n)
  • 50.83 (a)
Zfp157 16
chimpanzee
(Pan troglodytes)
Mammalia ZNF613 35
  • 99.68 (n)
  • 99.51 (a)
ZNF613 36
  • 100 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Zfp157 35
  • 59.48 (n)
  • 51.26 (a)
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 43 (a)
ManyToMany
-- 36
  • 45 (a)
ManyToMany
-- 36
  • 39 (a)
ManyToMany
-- 36
  • 42 (a)
ManyToMany
-- 36
  • 45 (a)
ManyToMany
-- 36
  • 46 (a)
ManyToMany
-- 36
  • 40 (a)
ManyToMany
-- 36
  • 38 (a)
ManyToMany
-- 36
  • 44 (a)
ManyToMany
-- 36
  • 45 (a)
ManyToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 39 (a)
OneToMany
Species with no ortholog for ZNF613:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF613 Gene

ENSEMBL:
Gene Tree for ZNF613 (if available)
TreeFam:
Gene Tree for ZNF613 (if available)

Paralogs for ZNF613 Gene

Paralogs for ZNF613 Gene

(513) SIMAP similar genes for ZNF613 Gene using alignment to 3 proteins:

genes like me logo Genes that share paralogs with ZNF613: view

Variants for ZNF613 Gene

Sequence variations from dbSNP and Humsavar for ZNF613 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
rs17854933 - 51,944,133(+) AAGTT(A/G)ACAAT reference, missense
rs8106409 - 51,944,160(+) CACAA(A/G)AGCAA reference, missense
rs16983243 - 51,944,287(+) GAAAA(G/T)ACTGA reference, missense
rs33998555 - 51,944,371(+) GAAAT(C/T)CTTCC reference, missense
rs16983253 - 51,945,715(+) AGCAG(A/T)TAGTA reference, missense

Structural Variations from Database of Genomic Variants (DGV) for ZNF613 Gene

Variant ID Type Subtype PubMed ID
esv638 CNV CNV 17122850
dgv143e55 CNV Gain 17911159
dgv1112e1 CNV Complex 17122850
dgv425n27 CNV Gain 19166990
dgv1113e1 CNV Complex 17122850
nsv833872 CNV Loss 17160897

Variation tolerance for ZNF613 Gene

Residual Variation Intolerance Score: 49.9% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.44; 42.98% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for ZNF613 Gene

Disorders for ZNF613 Gene

Relevant External Links for ZNF613

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ZNF613

No disorders were found for ZNF613 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF613 Gene

Publications for ZNF613 Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 67
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3

Products for ZNF613 Gene

Sources for ZNF613 Gene

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