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Aliases for ZNF611 Gene

Aliases for ZNF611 Gene

  • Zinc Finger Protein 611 2 3 5

External Ids for ZNF611 Gene

Previous GeneCards Identifiers for ZNF611 Gene

  • GC19M057899
  • GC19M057897
  • GC19M053207
  • GC19M049535

Summaries for ZNF611 Gene

GeneCards Summary for ZNF611 Gene

ZNF611 (Zinc Finger Protein 611) is a Protein Coding gene. Among its related pathways are Gene Expression. GO annotations related to this gene include nucleic acid binding and transcription factor activity, sequence-specific DNA binding. An important paralog of this gene is ZNF860.

UniProtKB/Swiss-Prot for ZNF611 Gene

  • May be involved in transcriptional regulation.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF611 Gene

Genomics for ZNF611 Gene

Regulatory Elements for ZNF611 Gene

Promoters for ZNF611 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around ZNF611 on UCSC Golden Path with GeneCards custom track

Genomic Location for ZNF611 Gene

Chromosome:
19
Start:
52,702,813 bp from pter
End:
52,735,073 bp from pter
Size:
32,261 bases
Orientation:
Minus strand

Genomic View for ZNF611 Gene

Genes around ZNF611 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF611 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF611 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF611 Gene

Proteins for ZNF611 Gene

  • Protein details for ZNF611 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8N823-ZN611_HUMAN
    Recommended name:
    Zinc finger protein 611
    Protein Accession:
    Q8N823
    Secondary Accessions:
    • B3KRD5
    • Q69YG9

    Protein attributes for ZNF611 Gene

    Size:
    705 amino acids
    Molecular mass:
    81449 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ZNF611 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZNF611 Gene

Proteomics data for ZNF611 Gene at MOPED

Post-translational modifications for ZNF611 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for ZNF611 Gene

Domains & Families for ZNF611 Gene

Gene Families for ZNF611 Gene

Protein Domains for ZNF611 Gene

Suggested Antigen Peptide Sequences for ZNF611 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q8N823

UniProtKB/Swiss-Prot:

ZN611_HUMAN :
  • Contains 1 KRAB domain.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 17 C2H2-type zinc fingers.
Domain:
  • Contains 1 KRAB domain.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 17 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF611: view

Function for ZNF611 Gene

Molecular function for ZNF611 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.
genes like me logo Genes that share phenotypes with ZNF611: view

Animal Model Products

CRISPR Products

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF611 Gene

Localization for ZNF611 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF611 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF611 Gene COMPARTMENTS Subcellular localization image for ZNF611 gene
Compartment Confidence
nucleus 5

No data available for Gene Ontology (GO) - Cellular Components for ZNF611 Gene

Pathways & Interactions for ZNF611 Gene

SuperPathways for ZNF611 Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF611: view

Pathways by source for ZNF611 Gene

2 Reactome pathways for ZNF611 Gene

Interacting Proteins for ZNF611 Gene

Gene Ontology (GO) - Biological Process for ZNF611 Gene

None

No data available for SIGNOR curated interactions for ZNF611 Gene

Drugs & Compounds for ZNF611 Gene

No Compound Related Data Available

Transcripts for ZNF611 Gene

Unigene Clusters for ZNF611 Gene

Zinc finger protein 611:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF611 Gene

No ASD Table

Relevant External Links for ZNF611 Gene

GeneLoc Exon Structure for
ZNF611
ECgene alternative splicing isoforms for
ZNF611

Expression for ZNF611 Gene

mRNA expression in normal human tissues for ZNF611 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

SOURCE GeneReport for Unigene cluster for ZNF611 Gene Hs.143951

genes like me logo Genes that share expression patterns with ZNF611: view

Primer Products

In Situ Assay Products

No data available for mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for ZNF611 Gene

Orthologs for ZNF611 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF611 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF611 35
  • 99.05 (n)
  • 98.44 (a)
-- 36
  • 79 (a)
ManyToMany
cow
(Bos Taurus)
Mammalia -- 36
  • 45 (a)
ManyToMany
dog
(Canis familiaris)
Mammalia -- 36
  • 50 (a)
ManyToMany
Species with no ortholog for ZNF611:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF611 Gene

ENSEMBL:
Gene Tree for ZNF611 (if available)
TreeFam:
Gene Tree for ZNF611 (if available)

Paralogs for ZNF611 Gene

(528) SIMAP similar genes for ZNF611 Gene using alignment to 7 proteins:

genes like me logo Genes that share paralogs with ZNF611: view

Variants for ZNF611 Gene

Sequence variations from dbSNP and Humsavar for ZNF611 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
rs4085566 - 52,706,300(-) GATAC(C/T)CCATT reference, missense
rs4087790 - 52,706,036(-) TGGAG(A/G)AAATC reference, missense
rs4085565 - 52,706,301(-) AGATA(A/C)CCCAT reference, missense
rs3884051 - 52,706,354(+) TCTCA(A/C/T)TACAT reference, missense
VAR_060722 -

Structural Variations from Database of Genomic Variants (DGV) for ZNF611 Gene

Variant ID Type Subtype PubMed ID
esv2718786 CNV Deletion 23290073
nsv833874 CNV Loss 17160897
esv2718787 CNV Deletion 23290073
dgv3980n71 CNV Gain 21882294
dgv3981n71 CNV Gain 21882294
nsv912311 CNV Gain 21882294
nsv458744 CNV Gain 19166990
esv2718794 CNV Deletion 23290073
nsv509752 CNV Insertion 20534489
dgv3983n71 CNV Loss 21882294
esv2718796 CNV Deletion 23290073
dgv3984n71 CNV Gain 21882294
esv2718797 CNV Deletion 23290073
esv2599883 CNV Deletion 19546169
esv7362 CNV Loss 19470904
nsv470152 CNV Gain 18288195
nsv458745 CNV Gain 19166990
nsv833875 CNV Loss 17160897
nsv912322 CNV Gain 21882294
esv2671531 CNV Deletion 23128226
nsv521828 CNV Loss 19592680
esv1709802 CNV Insertion 17803354

Variation tolerance for ZNF611 Gene

Residual Variation Intolerance Score: 91% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 9.05; 87.54% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ZNF611 Gene

HapMap Linkage Disequilibrium report
ZNF611

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF611 Gene

Disorders for ZNF611 Gene

Relevant External Links for ZNF611

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ZNF611

No disorders were found for ZNF611 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF611 Gene

Publications for ZNF611 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 67
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  3. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3

Products for ZNF611 Gene

Sources for ZNF611 Gene

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