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Aliases for ZNF611 Gene

Aliases for ZNF611 Gene

  • Zinc Finger Protein 611 2 3 5

External Ids for ZNF611 Gene

Previous GeneCards Identifiers for ZNF611 Gene

  • GC19M057899
  • GC19M057897
  • GC19M053207
  • GC19M049535

Summaries for ZNF611 Gene

GeneCards Summary for ZNF611 Gene

ZNF611 (Zinc Finger Protein 611) is a Protein Coding gene. Among its related pathways are Gene Expression. GO annotations related to this gene include nucleic acid binding and transcription factor activity, sequence-specific DNA binding. An important paralog of this gene is ZNF600.

UniProtKB/Swiss-Prot for ZNF611 Gene

  • May be involved in transcriptional regulation.

No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF611 Gene

Genomics for ZNF611 Gene

Regulatory Elements for ZNF611 Gene

Enhancers for ZNF611 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH19G052733 1.4 FANTOM5 ENCODE 23.4 -0.2 -197 2.8 HDGF ARID4B SIN3A ZNF48 ELK1 SP3 SP5 REST ZNF518A ZNF592 ZNF611 ZNF137P ENSG00000268970 ZNF701 TPM3P9 ZNF525 ZNF665 TPM3P6 ZNF28 ZNF845
GH19G052137 1.4 FANTOM5 ENCODE 11.7 +595.4 595442 3.3 PKNOX1 FOXA2 CREB3L1 ARNT WRNIP1 ARID4B SIN3A DMAP1 YY1 ZNF143 ZNF808 ZNF137P ENSG00000268970 ZNF816 ZNF350 ZNF836 ZNF600 ZNF468 ZNF616 ZNF841
GH19G053517 1.1 ENCODE 14.6 -784.5 -784542 4.8 FOXA2 PKNOX1 CREB3L1 ARNT ARID4B SIN3A YY1 ZNF766 ZNF302 ZNF143 ZNF137P ENSG00000268970 ZNF701 ZNF611 PRPF31 TPM3P9 ZNF665 ZNF525 LENG8-AS1 TPM3P6
GH19G051926 1.1 ENCODE 14.6 +807.7 807742 1.8 PKNOX1 CREB3L1 WRNIP1 ARID4B SIN3A FEZF1 DMAP1 ZNF2 YY1 SLC30A9 ZNF577 ZNF137P ZNF841 ZNF350-AS1 ENSG00000268970 ZNF701 ZNF611 ZNF28 ZNF578 ENSG00000269825
GH19G052026 1.1 ENCODE 14.6 +707.3 707250 2.8 HDGF PKNOX1 FOXA2 CREB3L1 ZFP64 ARID4B SIN3A FEZF1 DMAP1 ZNF2 ZNF137P ZNF841 ZNF432 ENSG00000268970 ZNF701 ZNF611 ZNF28 ZNF578 ZNF816 ENSG00000269825
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around ZNF611 on UCSC Golden Path with GeneCards custom track

Promoters for ZNF611 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000111324 473 1601 HDGF ARID4B SIN3A ZNF48 ELK1 SP3 SP5 REST ZNF518A ZNF592

Genomic Location for ZNF611 Gene

Chromosome:
19
Start:
52,702,813 bp from pter
End:
52,735,073 bp from pter
Size:
32,261 bases
Orientation:
Minus strand

Genomic View for ZNF611 Gene

Genes around ZNF611 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF611 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF611 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF611 Gene

Proteins for ZNF611 Gene

  • Protein details for ZNF611 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8N823-ZN611_HUMAN
    Recommended name:
    Zinc finger protein 611
    Protein Accession:
    Q8N823
    Secondary Accessions:
    • B3KRD5
    • Q69YG9

    Protein attributes for ZNF611 Gene

    Size:
    705 amino acids
    Molecular mass:
    81449 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ZNF611 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZNF611 Gene

Post-translational modifications for ZNF611 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for ZNF611 Gene

Domains & Families for ZNF611 Gene

Gene Families for ZNF611 Gene

Suggested Antigen Peptide Sequences for ZNF611 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q8N823

UniProtKB/Swiss-Prot:

ZN611_HUMAN :
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
genes like me logo Genes that share domains with ZNF611: view

Function for ZNF611 Gene

Molecular function for ZNF611 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Gene Ontology (GO) - Molecular Function for ZNF611 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
GO:0003700 transcription factor activity, sequence-specific DNA binding IBA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF611: view
genes like me logo Genes that share phenotypes with ZNF611: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

Clone Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF611 Gene

Localization for ZNF611 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF611 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZNF611 gene
Compartment Confidence
nucleus 5

Gene Ontology (GO) - Cellular Components for ZNF611 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular IEA --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF611: view

Pathways & Interactions for ZNF611 Gene

SuperPathways for ZNF611 Gene

SuperPathway Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF611: view

Pathways by source for ZNF611 Gene

2 Reactome pathways for ZNF611 Gene

Gene Ontology (GO) - Biological Process for ZNF611 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IBA --
genes like me logo Genes that share ontologies with ZNF611: view

No data available for SIGNOR curated interactions for ZNF611 Gene

Drugs & Compounds for ZNF611 Gene

No Compound Related Data Available

Transcripts for ZNF611 Gene

mRNA/cDNA for ZNF611 Gene

Unigene Clusters for ZNF611 Gene

Zinc finger protein 611:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF611 Gene

No ASD Table

Relevant External Links for ZNF611 Gene

GeneLoc Exon Structure for
ZNF611
ECgene alternative splicing isoforms for
ZNF611

Expression for ZNF611 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ZNF611 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

NURSA nuclear receptor signaling pathways regulating expression of ZNF611 Gene:

ZNF611

SOURCE GeneReport for Unigene cluster for ZNF611 Gene:

Hs.143951

Evidence on tissue expression from TISSUES for ZNF611 Gene

  • Nervous system(4.2)
genes like me logo Genes that share expression patterns with ZNF611: view

Primer Products

No data available for mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZNF611 Gene

Orthologs for ZNF611 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF611 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF611 34
  • 99.05 (n)
-- 35
  • 79 (a)
ManyToMany
dog
(Canis familiaris)
Mammalia -- 35
  • 50 (a)
ManyToMany
cow
(Bos Taurus)
Mammalia -- 35
  • 45 (a)
ManyToMany
Species where no ortholog for ZNF611 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF611 Gene

ENSEMBL:
Gene Tree for ZNF611 (if available)
TreeFam:
Gene Tree for ZNF611 (if available)

Paralogs for ZNF611 Gene

(528) SIMAP similar genes for ZNF611 Gene using alignment to 7 proteins:

genes like me logo Genes that share paralogs with ZNF611: view

Variants for ZNF611 Gene

Sequence variations from dbSNP and Humsavar for ZNF611 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
rs1000010703 -- 52,713,600(+) TCAAA(A/C)ACCAG intron-variant
rs1000029874 -- 52,734,911(+) AGAAT(G/T)TCCAG intron-variant
rs1000035996 -- 52,734,130(+) TGTAC(A/G)TCTAT intron-variant
rs1000063247 -- 52,713,800(+) GCAGG(A/G)GAATC intron-variant
rs1000111104 -- 52,733,167(+) GATAC(A/G)AATTT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF611 Gene

Variant ID Type Subtype PubMed ID
dgv3628n100 CNV gain 25217958
esv1709802 CNV insertion 17803354
esv2599883 CNV deletion 19546169
esv2671531 CNV deletion 23128226
esv2718786 CNV deletion 23290073
esv2718787 CNV deletion 23290073
esv2718794 CNV deletion 23290073
esv2718796 CNV deletion 23290073
esv2718797 CNV deletion 23290073
esv3556574 CNV deletion 23714750
esv3644714 CNV gain 21293372
esv3644715 CNV loss 21293372
esv3644716 CNV gain 21293372
esv3644717 CNV loss 21293372
esv3893231 CNV loss 25118596
esv3893233 CNV loss 25118596
esv3893234 CNV gain 25118596
esv7362 CNV loss 19470904
nsv1055617 CNV loss 25217958
nsv1057118 CNV gain 25217958
nsv1062976 CNV gain 25217958
nsv1066762 CNV gain 25217958
nsv1067557 CNV gain 25217958
nsv1078889 OTHER inversion 25765185
nsv1140479 CNV deletion 24896259
nsv1146332 OTHER inversion 26484159
nsv458744 CNV gain 19166990
nsv458745 CNV gain 19166990
nsv470152 CNV gain 18288195
nsv509752 CNV insertion 20534489
nsv521828 CNV loss 19592680
nsv580028 CNV gain 21841781
nsv580030 CNV gain 21841781
nsv580031 CNV gain 21841781
nsv833874 CNV loss 17160897
nsv833875 CNV loss 17160897
nsv961238 CNV duplication 23825009
nsv961239 CNV duplication 23825009

Variation tolerance for ZNF611 Gene

Residual Variation Intolerance Score: 91% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 9.05; 87.54% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ZNF611 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ZNF611

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF611 Gene

Disorders for ZNF611 Gene

Relevant External Links for ZNF611

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ZNF611

No disorders were found for ZNF611 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF611 Gene

Publications for ZNF611 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 64
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3 64
  3. The full-ORF clone resource of the German cDNA consortium. (PMID: 17974005) Bechtel S. … Schupp I. (BMC Genomics 2007) 4 64
  4. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3 64
  5. The DNA sequence and biology of human chromosome 19. (PMID: 15057824) Grimwood J. … Lucas S.M. (Nature 2004) 4 64

Products for ZNF611 Gene

Sources for ZNF611 Gene

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