ZNF611 Gene
protein-coding GIFtS: 44
GCID: GC19M053207
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zinc finger protein 611
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Aliases
for ZNF611 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Zinc Finger Protein 6111 2 | | MGC53841 |
Export aliases for ZNF611 gene to outside databasesPrevious GC identifers: GC19M057899 GC19M057897 GC19M049535 |
Summaries
for ZNF611 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
UniProtKB/Swiss-Prot: ZN611_HUMAN, Q8N823Function: May be involved in transcriptional regulation
|
Genomic Views
for ZNF611 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000019.9 NC_018930.1 NT_011109.16
Regulatory elements:
 Search SABiosciences Regulatory transcription factor binding sites for ZNF611
Other transcription factors
Search SABiosciences Chromatin IP Primers for ZNF611
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZNF611 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 19q13.41 Ensembl cytogenetic band: 19q13.41 HGNC cytogenetic band: 19q13.42ZNF611 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 19 GeneLoc Exon Structure GeneLoc location for GC19M053207: view genomic region
(about GC identifiers)
Start:
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53,206,066 bp from pter |
End:
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53,238,307 bp from pter |
Size:
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32,242 bases |
Orientation:
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minus strand |
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Proteins
for ZNF611 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: ZN611_HUMAN, Q8N823 (See
protein sequence)Recommended Name: Zinc finger protein 611 Size: 705 amino acids; 81449 Da
Subcellular location: Nucleus (Probable)
Secondary accessions: B3KRD5 Q69YG9Alternative splicing: 2 isoforms: Q8N823-1 Q8N823-2 Explore the universe of human proteins at neXtProt for ZNF611: NX_Q8N823
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q8N823
ZNF611 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (4 alternative transcripts):
NP_001154971.1 NP_001154972.1 NP_001154973.1 NP_112234.3
ENSEMBL proteins: ENSP00000322427 ENSP00000437616 ENSP00000439211 ENSP00000443505 Reactome Protein details: Q8N823
Human Recombinant Protein Products:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005634 | nucleus |
IEA | -- |
ZNF611 for ontologies About GeneDecksing
ZNF611 Antibody Products:
Assay Products for ZNF611: |
Protein
Domains /
Families
for ZNF611 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ZNF611 for domains About GeneDecksing
4 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q8N823ProtoNet protein and cluster: Q8N823 2 Blocks protein families: IPB001909 KRAB box IPB007086 C2H2-type zinc finger signature
UniProtKB/Swiss-Prot: ZN611_HUMAN, Q8N823Similarity: Belongs to the krueppel C2H2-type zinc-finger protein familySimilarity: Contains 17 C2H2-type zinc fingersSimilarity: Contains 1 KRAB domain |
Function
for ZNF611 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: ZN611_HUMAN, Q8N823Function: May be involved in transcriptional regulation
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF611 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF611 (see all 4)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 4): ZNF611 (NM_030972) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ZNF611 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF611 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF611 |
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table
ZNF611 for ontologies About GeneDecksing
|
Pathways & Interactions
for ZNF611 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Generic Transcription Pathway | |
Pathway sources
See GeneCards unified pathways
Show all pathways
2 
Reactome Pathways for ZNF611
ZNF611 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ZNF611
1 Interacting protein for ZNF611 (Q8N8233) via UniProtKB, MINT, STRING, and/or I2DAbout this table
Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006351 | transcription, DNA-dependent |
IEA | -- | | GO:0006355 | regulation of transcription, DNA-dependent |
IEA | -- |
ZNF611 for ontologies About GeneDecksing
|
Drugs & Compounds
for ZNF611 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for ZNF611
Search CenterWatch for drugs/clinical trials and news about ZNF611 / ZN611
|
Transcripts
for ZNF611 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for ZNF611 gene (4 alternative transcripts): NM_001161499.1 NM_001161500.1 NM_001161501.1 NM_030972.3 Unigene Cluster for ZNF611: Zinc finger protein 611 Hs.143951 [show with all ESTs]Unigene Representative Sequence: BC0285904 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000319783 ENST00000543227(uc010ydp.2 uc010ydr.2 uc002qaa.4)
ENST00000540744(uc010eqc.3 uc002pzz.3 uc010ydq.2) ENST00000453741(uc010ydo.2)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF611 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF611 (see all 4)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 4): ZNF611 (NM_030972) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ZNF611 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF611 |
Additional cDNA sequence: AK021787.1 AK091389.1 AK097434.1 AK098776.1 AL834123.1 BC000918.2 BC028590.1 BC071949.1 BC136343.1 BC143996.1 14 DOTS entries: DT.95207791 DT.86837062 DT.97774348 DT.100797473 DT.121462132 DT.91758862 DT.92416069 DT.121461945 DT.121462295 DT.101974377 DT.121462205 DT.95214051 DT.95320829 DT.97824957 14 AceView cDNA sequences: BX476019 BX957119 BC028590 AI866321 BM684943 AW408695 AK098776 AL598671 BI560214 AW504024 BQ436193 BU902297 BM931886 AV748174
GeneLoc Exon Structure
|
Expression
for ZNF611 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ZNF611 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --
About this image
See ZNF611 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for ZNF611
SOURCE GeneReport for Unigene cluster: Hs.143951
SABiosciences Custom PCR Arrays for ZNF611
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZNF611
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat ZNF611 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZNF611 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZNF611 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF611 |
Orthologs
for ZNF611 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
--
ENSEMBL Gene Tree for ZNF611 (if available)
TreeFam Gene Tree for ZNF611 (if available) |
Paralogs
for ZNF611 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for ZNF611 gene
- ZNF5342 ZNF321P2 ZNF4682 ZNF5782 ZNF8802 ZNF7662 ZNF3202 ZNF5252
- ZNF8602 ZNF4152 ZNF6002 ZNF282 ZNF5282 ZNF6772 ZNF832 ZNF8162
- ZNF6102 ZNF7012 ZNF7652 ZNF4802 ZNF8132
18/490 SIMAP similar genes for ZNF611 using alignment to 7 protein entries: ZN611_HUMAN (see all proteins)
(see all similar genes):ZNF600 kr-znf3 ZNF808 ZNF321P ZNF845 ZNF813
ZFS-5 ZNF28 ZNF765 ZNF761 ZNF578 ZNF701
ZNF167 ZNF738 ZNF78L1 ZNF816 ZNF534 ZNF525
ZNF611 for paralogs About GeneDecksing
|
Genomic Variants
for ZNF611 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 19 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for ZNF611 (53206066 - 53238307 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 2 variations for ZNF611
2 CNVs: 61713 102868 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ZNF611 |
|
Disorders
/ Diseases
for ZNF611 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications
for ZNF611 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ZNF611 gene integrated from 9 sources:
(articles sorted by number of sources associating them with ZNF611) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (2002)
- Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)
- The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (2007)
- Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)
- The DNA sequence and biology of human chromosome 19. (PubMed id 15057824)2 Grimwood J.... Lucas S.M. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
|
External Searches for ZNF611 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing ZNF611 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing ZNF611 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing ZNF611 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for ZNF611 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for ZNF611 gene:
Search GeneIP for patents involving ZNF611
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for ZNF611 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | Browse OriGene shRNA RFPs | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ZNF611 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZNF611 | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for ZNF611 | | OriGene 3'-UTR Clone for ZNF611 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF611 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF611 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for ZNF611 | | OriGene Custom Protein Services for ZNF611 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ZNF611 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ZNF611 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZNF611 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ZNF611 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZNF611 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZNF611 |
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 |  |  |  | |
| | | | Search Tocris compounds for ZNF611 |
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 | | | ZNF611 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF611 |
|  |  |  | | | | ThermoFisher Antibodies for ZNF611 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF611 |
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