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Aliases for ZNF608 Gene

Aliases for ZNF608 Gene

  • Zinc Finger Protein 608 2 3
  • Renal Carcinoma Antigen NY-REN-36 3 4
  • NY-REN-36 3
  • KIAA1281 4

External Ids for ZNF608 Gene

Previous GeneCards Identifiers for ZNF608 Gene

  • GC05M124049
  • GC05M124000
  • GC05M123966
  • GC05M119162

Summaries for ZNF608 Gene

GeneCards Summary for ZNF608 Gene

ZNF608 (Zinc Finger Protein 608) is a Protein Coding gene. An important paralog of this gene is ZNF609.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF608 Gene

Genomics for ZNF608 Gene

Regulatory Elements for ZNF608 Gene

Genomic Location for ZNF608 Gene

124,636,913 bp from pter
124,748,824 bp from pter
111,912 bases
Minus strand

Genomic View for ZNF608 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZNF608 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF608 Gene

Proteins for ZNF608 Gene

  • Protein details for ZNF608 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Zinc finger protein 608
    Protein Accession:
    Secondary Accessions:
    • A7E2W9
    • Q3SYM6
    • Q68D12
    • Q8IY05
    • Q9Y5A1

    Protein attributes for ZNF608 Gene

    1512 amino acids
    Molecular mass:
    162208 Da
    Quaternary structure:
    No Data Available
    • Antigen recognized by autologous antibody in patients with renal-cell carcinoma
    • Sequence=BAA86595.2; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305};

    Alternative splice isoforms for ZNF608 Gene


neXtProt entry for ZNF608 Gene

Proteomics data for ZNF608 Gene at MOPED

Post-translational modifications for ZNF608 Gene

  • Ubiquitination at Lys1250
  • Modification sites at PhosphoSitePlus

Other Protein References for ZNF608 Gene

No data available for DME Specific Peptides for ZNF608 Gene

Domains for ZNF608 Gene

Gene Families for ZNF608 Gene

Protein Domains for ZNF608 Gene


Graphical View of Domain Structure for InterPro Entry



  • Contains 1 C2H2-type zinc finger.
  • Contains 1 C2H2-type zinc finger.
genes like me logo Genes that share domains with ZNF608: view

Function for ZNF608 Gene

Gene Ontology (GO) - Molecular Function for ZNF608 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF608: view

Phenotypes for ZNF608 Gene

GenomeRNAi human phenotypes for ZNF608:
genes like me logo Genes that share phenotypes with ZNF608: view

Animal Model Products

CRISPR Products

miRNA for ZNF608 Gene

miRTarBase miRNAs that target ZNF608

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZNF608

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF608 Gene

Localization for ZNF608 Gene

Subcellular locations from

Jensen Localization Image for ZNF608 Gene COMPARTMENTS Subcellular localization image for ZNF608 gene
Compartment Confidence
nucleus 3
cytosol 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for ZNF608 Gene

Pathways for ZNF608 Gene

SuperPathways for ZNF608 Gene

No Data Available

Interacting Proteins for ZNF608 Gene

Gene Ontology (GO) - Biological Process for ZNF608 Gene


No data available for Pathways by source for ZNF608 Gene

Transcripts for ZNF608 Gene

Unigene Clusters for ZNF608 Gene

Zinc finger protein 608:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZNF608

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF608 Gene

ExUns: 1 ^ 2a · 2b ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9a · 9b · 9c ^ 10a · 10b ^ 11 ^ 12 ^ 13 ^ 14
SP1: -
SP3: - -
SP4: - - - - - - -

Relevant External Links for ZNF608 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ZNF608 Gene

mRNA expression in normal human tissues for ZNF608 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues for ZNF608 Gene

This gene is overexpressed in Breast (24.0), Blymphocyte (18.8), Monocytes (8.1), and Tlymphocyte (6.2).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for ZNF608 Gene

SOURCE GeneReport for Unigene cluster for ZNF608 Gene Hs.266616

genes like me logo Genes that share expressions with ZNF608: view

Expression partners for ZNF608 Gene

* - Elite partner

Primer Products

In Situ Assay Products

No data available for mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ZNF608 Gene

Orthologs for ZNF608 Gene

This gene was present in the common ancestor of animals.

Orthologs for ZNF608 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia ZNF608 35
  • 92.18 (n)
  • 94.96 (a)
ZNF608 36
  • 95 (a)
(Canis familiaris)
Mammalia ZNF608 35
  • 90.12 (n)
  • 93.58 (a)
ZNF608 36
  • 92 (a)
(Mus musculus)
Mammalia Zfp608 35
  • 89.85 (n)
  • 93.12 (a)
Zfp608 16
Zfp608 36
  • 93 (a)
(Pan troglodytes)
Mammalia ZNF608 35
  • 99.65 (n)
  • 99.6 (a)
ZNF608 36
  • 100 (a)
(Rattus norvegicus)
Mammalia Zfp608 35
  • 89.44 (n)
  • 91.99 (a)
(Monodelphis domestica)
Mammalia ZNF608 36
  • 86 (a)
(Ornithorhynchus anatinus)
Mammalia ZNF608 36
  • 87 (a)
(Gallus gallus)
Aves ZNF608 35
  • 82.97 (n)
  • 86.09 (a)
ZNF608 36
  • 85 (a)
(Anolis carolinensis)
Reptilia ZNF608 36
  • 84 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia Str.10279 35
znf608 35
  • 72.51 (n)
  • 76.22 (a)
(Danio rerio)
Actinopterygii LOC100329407 35
  • 54.2 (n)
  • 47.72 (a)
ZNF608 36
  • 41 (a)
fruit fly
(Drosophila melanogaster)
Insecta sbb 36
  • 14 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 55 (a)
Species with no ortholog for ZNF608:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ZNF608 Gene

Gene Tree for ZNF608 (if available)
Gene Tree for ZNF608 (if available)

Paralogs for ZNF608 Gene

Paralogs for ZNF608 Gene

(2) SIMAP similar genes for ZNF608 Gene using alignment to 4 proteins:

genes like me logo Genes that share paralogs with ZNF608: view

Variants for ZNF608 Gene

Sequence variations from dbSNP and Humsavar for ZNF608 Gene

SNP ID Clin Chr 05 pos Sequence Context AA Info Type MAF
rs1133492 -- 124,726,647(+) agtca(A/G)cagta intron-variant
rs3860117 -- 124,707,325(+) CTGCC(A/G)AGAAG intron-variant
rs3922625 -- 124,708,970(-) ggtct(C/T)gaact intron-variant
rs4277913 -- 124,730,250(+) ATTTT(C/T)TAGAT intron-variant
rs4282308 -- 124,690,450(+) atgga(G/T)acgct intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF608 Gene

Variant ID Type Subtype PubMed ID
nsv882818 CNV Gain 21882294
nsv830473 CNV Gain 17160897
esv274116 CNV Insertion 20981092

Relevant External Links for ZNF608 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF608 Gene

Disorders for ZNF608 Gene

Relevant External Links for ZNF608

Genetic Association Database (GAD)

No disorders were found for ZNF608 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships and Genatlas for ZNF608 Gene

Publications for ZNF608 Gene

  1. Antigens recognized by autologous antibody in patients with renal- cell carcinoma. (PMID: 10508479) Scanlan M.J. … Old L.J. (Int. J. Cancer 1999) 2 3 4
  2. Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PMID: 10574462) Nagase T. … Ohara O. (DNA Res. 1999) 2 3 4
  3. Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones. (PMID: 12168954) Nakajima D. … Nagase T. (DNA Res. 2002) 3 4
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  5. Toward a confocal subcellular atlas of the human proteome. (PMID: 18029348) Barbe L. … Andersson-Svahn H. (Mol. Cell Proteomics 2008) 3

Products for ZNF608 Gene

Sources for ZNF608 Gene

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