ZNF607 Gene
protein-coding GIFtS: 47
GCID: GC19M038187
|
|
zinc finger protein 607
| |
Aliases
for ZNF607 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Zinc Finger Protein 6071 2 | | FLJ148021 | | MGC130711 |
Export aliases for ZNF607 gene to outside databasesPrevious GC identifers: GC19M042880 GC19M042881 GC19M034637 |
Summaries
for ZNF607 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
UniProtKB/Swiss-Prot: ZN607_HUMAN, Q96SK3Function: May be involved in transcriptional regulation
|
Genomic Views
for ZNF607 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000019.9 NC_018930.1 NT_011109.16
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the ZNF607 gene promoter:
Ik-2 Ik-1
Other transcription factors
Search SABiosciences Chromatin IP Primers for ZNF607
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZNF607 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 19q13.1 Ensembl cytogenetic band: 19q13.12 HGNC cytogenetic band: 19q13.1ZNF607 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 19 GeneLoc Exon Structure GeneLoc location for GC19M038187: view genomic region
(about GC identifiers)
Start:
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38,180,785 bp from pter |
End:
|
38,210,691 bp from pter |
Size:
|
29,907 bases |
Orientation:
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minus strand |
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Proteins
for ZNF607 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: ZN607_HUMAN, Q96SK3 (See
protein sequence)Recommended Name: Zinc finger protein 607 Size: 696 amino acids; 80507 Da
Subcellular location: Nucleus (Potential)
Secondary accessions: Q6ZMN4 Q96C40Alternative splicing: 2 isoforms: Q96SK3-1 Q96SK3-2 Explore the universe of human proteins at neXtProt for ZNF607: NX_Q96SK3
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q96SK3
ZNF607 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_001166148.1 NP_116078.4
ENSEMBL proteins: ENSP00000466284 ENSP00000347338 ENSP00000438015 ENSP00000466265 ENSP00000466785 ENSP00000468817 Reactome Protein details: Q96SK3
Human Recombinant Protein Products:
Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table
ZNF607 for ontologies About GeneDecksing
ZNF607 Antibody Products:
Assay Products for ZNF607: |
Protein
Domains /
Families
for ZNF607 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ZNF607 for domains About GeneDecksing
4 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q96SK3ProtoNet protein and cluster: Q96SK3 1 Blocks protein family: IPB007086 C2H2-type zinc finger signature
UniProtKB/Swiss-Prot: ZN607_HUMAN, Q96SK3Similarity: Belongs to the krueppel C2H2-type zinc-finger protein familySimilarity: Contains 20 C2H2-type zinc fingersSimilarity: Contains 1 KRAB domain |
Function
for ZNF607 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: ZN607_HUMAN, Q96SK3Function: May be involved in transcriptional regulation
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF607 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF607 (see all 3)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 2): ZNF607 (NM_032689) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ZNF607 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF607 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF607 |
Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table
ZNF607 for ontologies About GeneDecksing
|
Pathways & Interactions
for ZNF607 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Generic Transcription Pathway | |
Pathway sources
See GeneCards unified pathways
Show all pathways
2 
Reactome Pathways for ZNF607
ZNF607 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ZNF607
STRING Interaction
Network Preview (showing 1 interactants - click image to see more details)
3 Interacting proteins for ZNF607 (Q96SK33 ENSP000003473384) via UniProtKB, MINT, STRING, and/or I2DAbout this table
Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006351 | transcription, DNA-dependent |
IEA | -- | | GO:0006355 | regulation of transcription, DNA-dependent |
IEA | -- |
ZNF607 for ontologies About GeneDecksing
|
Drugs & Compounds
for ZNF607 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for ZNF607
Search CenterWatch for drugs/clinical trials and news about ZNF607 / ZN607
|
Transcripts
for ZNF607 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for ZNF607 gene (2 alternative transcripts): NM_001172677.1 NM_032689.4 Unigene Cluster for ZNF607: Zinc finger protein 607 Hs.116622 [show with all ESTs]Unigene Representative Sequence: NM_0326896 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000591114 ENST00000355202(uc002ohc.2) ENST00000395835(uc002ohb.2)
ENST00000586559 ENST00000590670 ENST00000591664
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF607 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF607 (see all 3)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 2): ZNF607 (NM_032689) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ZNF607 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF607 |
Additional cDNA sequence: AB209242.1 AK027708.1 AK127464.1 AK131557.1 AK131559.1 BC005085.1 BC014850.1 5 DOTS entries: DT.99986710 DT.408823 DT.102821167 DT.99973278 DT.121294986 24/36 AceView cDNA sequences (see all 36): AK027708 AI335883 BM833114 BC005085 BM758133 BU508376 BF771882 BE549509 BE562558 BX442094 BX496992 BX096709 AA296661 BC014850 N58717 AK131557 AW956332 NM_032689 AK127464 AK131559 N54277 BU622679 H61231 AI270607
GeneLoc Exon Structure
5/6 Alternative Splicing Database (ASD) splice patterns (SP) for ZNF607 (see all 6) About this scheme
| ExUns: | 1 | ^ | 2a | · | 2b | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7a | · | 7b | · | 7c | · | 7d | · | 7e |
|---|
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| SP1: | | | - | | - | | - | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | - | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | - | | | | | | - | | | | | | | | | | | | |
| SP5: | | | | | | | | | - | | - | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for ZNF607
|
Expression
for ZNF607 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ZNF607 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: AAATATACTG
About this image
See ZNF607 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for ZNF607
SOURCE GeneReport for Unigene cluster: Hs.116622
SABiosciences Custom PCR Arrays for ZNF607
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZNF607
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat ZNF607 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZNF607 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZNF607 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF607 |
Orthologs
for ZNF607 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
--
ENSEMBL Gene Tree for ZNF607 (if available)
TreeFam Gene Tree for ZNF607 (if available) |
Paralogs
for ZNF607 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for ZNF607 gene
- ZNF4202 ZNF5292 ZFP302 ZNF1402 ZNF780A2 ZNF3832 ZNF7902 ZNF5822
- ZFP822 ZNF302 ZNF5732 ZNF5402 ZNF5712 ZNF3312 ZFP142 ZNF4612
- ZNF2832 ZNF4042 ZNF8292 ZNF5652 ZNF5662 ENSG000002675522
18/531 SIMAP similar genes for ZNF607 using alignment to 7 protein entries: ZN607_HUMAN (see all proteins)
(see all similar genes):PHB ZFP90 ZNF78L1 ZNF232 ZFS-1 ZNF826P
ZNF75A kr-znf3 ZNF573 ZNF84 ZNF66 ZNF577
ZNF397 ZNF721 ZFP14 ZFS-4 ZNF56 ZNF283
ZNF607 for paralogs About GeneDecksing
3 Pseudogenes.org Pseudogenes for ZNF607
PGOHUM00000234300 PGOHUM00000234684 PGOHUM00000240085
|
Genomic Variants
for ZNF607 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 19 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for ZNF607 (38180785 - 38210691 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for ZNF607
1 CNV: 5099 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ZNF607 |
|
Disorders
/ Diseases
for ZNF607 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
 ZNF607 for disorders About MalaCards
ZNF607 for disorders About GeneDecksing
Human Genome Epidemiology (HuGE) Navigator: ZNF607 (2 documents)
Export disorders for ZNF607 gene to outside databases
|
Publications
for ZNF607 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ZNF607 gene integrated from 9 sources:
(articles sorted by number of sources associating them with ZNF607) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2, 3 Ota T.... Sugano S. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Assessment of a polymorphism of SDK1 with hypertensio n in Japanese Individuals. (PubMed id 19851296)1 Oguri M....Yamada Y. (2010)
- Association of genetic variants with hemorrhagic stro ke in Japanese individuals. (PubMed id 20198315)1 Yoshida T....Yamada Y. (2010)
- Towards a proteome-scale map of the human protein-protein interaction network. (PubMed id 16189514)1 Rual J.F....Vidal M. (2005)
- The DNA sequence and biology of human chromosome 19. (PubMed id 15057824)2 Grimwood J.... Lucas S.M. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
|
External Searches for ZNF607 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing ZNF607 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing ZNF607 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing ZNF607 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for ZNF607 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for ZNF607 gene:
Search GeneIP for patents involving ZNF607
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for ZNF607 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for ZNF607 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ZNF607 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZNF607 | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for ZNF607 | | OriGene 3'-UTR Clone for ZNF607 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF607 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF607 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for ZNF607 | | OriGene Custom Protein Services for ZNF607 | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ZNF607 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ZNF607 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZNF607 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ZNF607 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZNF607 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZNF607 |
| |
 |  |  |  | |
| | | | Search Tocris compounds for ZNF607 |
| |  |  |  |  | | | | |
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 |
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 | | | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF607 |
|  |  |  | | | | Search ThermoFisher Antibodies for ZNF607 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF607 |
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