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Aliases for ZNF607 Gene

Aliases for ZNF607 Gene

  • Zinc Finger Protein 607 2 3 5

External Ids for ZNF607 Gene

Previous GeneCards Identifiers for ZNF607 Gene

  • GC19M042880
  • GC19M042881
  • GC19M038187
  • GC19M034637

Summaries for ZNF607 Gene

GeneCards Summary for ZNF607 Gene

ZNF607 (Zinc Finger Protein 607) is a Protein Coding gene. Among its related pathways are Gene Expression. GO annotations related to this gene include nucleic acid binding and transcription factor activity, sequence-specific DNA binding. An important paralog of this gene is ZNF30.

UniProtKB/Swiss-Prot for ZNF607 Gene

  • May be involved in transcriptional regulation.

No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF607 Gene

Genomics for ZNF607 Gene

Regulatory Elements for ZNF607 Gene

Enhancers for ZNF607 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH19G038673 2.1 FANTOM5 Ensembl ENCODE dbSUPER 71.8 -975.1 -975097 42.0 MLX CREB3L1 AGO1 ZFP64 FEZF1 DMAP1 YY1 SLC30A9 ZNF143 ZNF416 ZNF573 ZNF607 EID2B ACTN4 ENSG00000267152 RN7SL566P RPS16 LOC100631378 CAPN12 SUPT5H
GH19G037973 1.9 FANTOM5 Ensembl ENCODE dbSUPER 71.1 -258.8 -258777 10.0 HDGF PKNOX1 WRNIP1 DMAP1 YBX1 ZNF2 YY1 CBX5 ZNF143 ZNF207 ZNF585B ZNF793 ZNF585A ZNF607 ZNF420 ZNF781 ENSG00000267152 ZNF573 ZNF383 WDR87
GH19G038647 1.8 FANTOM5 ENCODE dbSUPER 68.7 -940.0 -940003 25.6 CREB3L1 MLX AGO1 ZFP64 FEZF1 DMAP1 YY1 ZNF143 ZNF548 ZNF263 ZNF781 ZNF607 ENSG00000267152 ZNF573 EID2B ENSG00000267892 CAPN12 ACTN4 RPS16 MED29
GH19G037930 1.9 FANTOM5 Ensembl ENCODE dbSUPER 45.7 -218.5 -218528 16.0 HDGF PKNOX1 ARNT ARID4B SIN3A DMAP1 YY1 SLC30A9 CBX5 ZNF143 ZNF793 ZNF607 LINC01535 ZNF585B ZNF781 ZNF585A ENSG00000267152 ZNF420 WDR87 LOC100631378
GH19G038262 1.4 ENCODE dbSUPER 59.3 -546.1 -546076 6.7 HDGF FOXA2 PKNOX1 MLX AGO1 ZFP64 SIN3A ARID4B DMAP1 ZNF2 ZNF573 ZNF607 ZNF793 ZNF569 C19orf33 ZNF570 CATSPERG LOC100631378 PPP1R14A LOC284412
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around ZNF607 on UCSC Golden Path with GeneCards custom track

Promoters for ZNF607 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000109176 490 1801 CREB3L1 AGO1 ARID4B SIN3A DMAP1 ZNF2 SLC30A9 ZNF302 ZNF207 ZNF143

Transcription factor binding sites by QIAGEN in the ZNF607 gene promoter:

Genomic Location for ZNF607 Gene

Chromosome:
19
Start:
37,696,363 bp from pter
End:
37,719,790 bp from pter
Size:
23,428 bases
Orientation:
Minus strand

Genomic View for ZNF607 Gene

Genes around ZNF607 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF607 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF607 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF607 Gene

Proteins for ZNF607 Gene

  • Protein details for ZNF607 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q96SK3-ZN607_HUMAN
    Recommended name:
    Zinc finger protein 607
    Protein Accession:
    Q96SK3
    Secondary Accessions:
    • F5H141
    • Q6ZMN2
    • Q6ZMN4
    • Q96C40

    Protein attributes for ZNF607 Gene

    Size:
    696 amino acids
    Molecular mass:
    80507 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ZNF607 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZNF607 Gene

Post-translational modifications for ZNF607 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for ZNF607 Gene

Domains & Families for ZNF607 Gene

Gene Families for ZNF607 Gene

Suggested Antigen Peptide Sequences for ZNF607 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q96SK3

UniProtKB/Swiss-Prot:

ZN607_HUMAN :
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
genes like me logo Genes that share domains with ZNF607: view

Function for ZNF607 Gene

Molecular function for ZNF607 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Gene Ontology (GO) - Molecular Function for ZNF607 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
GO:0003700 transcription factor activity, sequence-specific DNA binding IBA --
GO:0005515 protein binding IPI 16189514
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF607: view
genes like me logo Genes that share phenotypes with ZNF607: view

Animal Model Products

CRISPR Products

miRNA for ZNF607 Gene

miRTarBase miRNAs that target ZNF607

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF607 Gene

Localization for ZNF607 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF607 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZNF607 gene
Compartment Confidence
nucleus 5
cytosol 2

Gene Ontology (GO) - Cellular Components for ZNF607 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular IEA --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF607: view

Pathways & Interactions for ZNF607 Gene

SuperPathways for ZNF607 Gene

SuperPathway Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF607: view

Pathways by source for ZNF607 Gene

2 Reactome pathways for ZNF607 Gene

Gene Ontology (GO) - Biological Process for ZNF607 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IBA,IEA --
genes like me logo Genes that share ontologies with ZNF607: view

No data available for SIGNOR curated interactions for ZNF607 Gene

Transcripts for ZNF607 Gene

Unigene Clusters for ZNF607 Gene

Zinc finger protein 607:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF607 Gene

ExUns: 1 ^ 2a · 2b ^ 3 ^ 4 ^ 5 ^ 6 ^ 7a · 7b · 7c · 7d · 7e
SP1: - - -
SP2: -
SP3:
SP4: - -
SP5: - -
SP6: - - -

Relevant External Links for ZNF607 Gene

GeneLoc Exon Structure for
ZNF607
ECgene alternative splicing isoforms for
ZNF607

Expression for ZNF607 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ZNF607 Gene

mRNA differential expression in normal tissues according to GTEx for ZNF607 Gene

This gene is overexpressed in Testis (x8.1).

Protein differential expression in normal tissues from HIPED for ZNF607 Gene

This gene is overexpressed in Peripheral blood mononuclear cells (60.3) and Heart (8.7).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for ZNF607 Gene



Protein tissue co-expression partners for ZNF607 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of ZNF607 Gene:

ZNF607

SOURCE GeneReport for Unigene cluster for ZNF607 Gene:

Hs.116622
genes like me logo Genes that share expression patterns with ZNF607: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZNF607 Gene

Orthologs for ZNF607 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZNF607 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF607 34
  • 99.62 (n)
cow
(Bos Taurus)
Mammalia LOC787397 34
  • 74.08 (n)
dog
(Canis familiaris)
Mammalia LOC102156679 34
  • 73.63 (n)
oppossum
(Monodelphis domestica)
Mammalia -- 35
  • 46 (a)
OneToMany
-- 35
  • 45 (a)
OneToMany
-- 35
  • 44 (a)
OneToMany
-- 35
  • 44 (a)
OneToMany
-- 35
  • 44 (a)
OneToMany
-- 35
  • 43 (a)
OneToMany
-- 35
  • 43 (a)
OneToMany
-- 35
  • 43 (a)
OneToMany
-- 35
  • 42 (a)
OneToMany
-- 35
  • 42 (a)
OneToMany
-- 35
  • 42 (a)
OneToMany
-- 35
  • 42 (a)
OneToMany
-- 35
  • 42 (a)
OneToMany
-- 35
  • 42 (a)
OneToMany
-- 35
  • 42 (a)
OneToMany
-- 35
  • 41 (a)
OneToMany
-- 35
  • 41 (a)
OneToMany
-- 35
  • 41 (a)
OneToMany
-- 35
  • 41 (a)
OneToMany
-- 35
  • 41 (a)
OneToMany
-- 35
  • 40 (a)
OneToMany
-- 35
  • 39 (a)
OneToMany
-- 35
  • 39 (a)
OneToMany
-- 35
  • 39 (a)
OneToMany
-- 35
  • 39 (a)
OneToMany
-- 35
  • 39 (a)
OneToMany
-- 35
  • 38 (a)
OneToMany
-- 35
  • 38 (a)
OneToMany
-- 35
  • 38 (a)
OneToMany
-- 35
  • 37 (a)
OneToMany
-- 35
  • 37 (a)
OneToMany
-- 35
  • 36 (a)
OneToMany
-- 35
  • 35 (a)
OneToMany
-- 35
  • 35 (a)
OneToMany
-- 35
  • 35 (a)
OneToMany
mouse
(Mus musculus)
Mammalia Gm13051 35
  • 41 (a)
OneToMany
Gm13150 35
  • 41 (a)
OneToMany
Gm13151 35
  • 40 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia ZNF607 35
  • 40 (a)
OneToOne
Species where no ortholog for ZNF607 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF607 Gene

ENSEMBL:
Gene Tree for ZNF607 (if available)
TreeFam:
Gene Tree for ZNF607 (if available)

Paralogs for ZNF607 Gene

(528) SIMAP similar genes for ZNF607 Gene using alignment to 5 proteins:

Pseudogenes.org Pseudogenes for ZNF607 Gene

genes like me logo Genes that share paralogs with ZNF607: view

Variants for ZNF607 Gene

Sequence variations from dbSNP and Humsavar for ZNF607 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
rs1000011566 -- 37,704,952(+) CTAAA(-/AAAC)AAACA intron-variant
rs1000015421 -- 37,707,644(+) CACTT(C/G)TGGTC intron-variant
rs1000033135 -- 37,717,639(+) AAAAA(A/T)ACAAA intron-variant
rs1000039084 -- 37,717,535(+) TCACG(A/C)CTGTA intron-variant
rs1000343345 -- 37,705,270(+) TCAAT(C/T)TGACA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF607 Gene

Variant ID Type Subtype PubMed ID
nsv579468 CNV gain 21841781
nsv833820 CNV loss 17160897
nsv978813 CNV duplication 23825009

Variation tolerance for ZNF607 Gene

Residual Variation Intolerance Score: 46% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 7.39; 81.75% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ZNF607 Gene

Human Gene Mutation Database (HGMD)
ZNF607
SNPedia medical, phenotypic, and genealogical associations of SNPs for
ZNF607

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF607 Gene

Disorders for ZNF607 Gene

Relevant External Links for ZNF607

Genetic Association Database (GAD)
ZNF607
Human Genome Epidemiology (HuGE) Navigator
ZNF607
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ZNF607

No disorders were found for ZNF607 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF607 Gene

Publications for ZNF607 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 2 3 4 64
  2. Assessment of a polymorphism of SDK1 with hypertension in Japanese Individuals. (PMID: 19851296) Oguri M. … Yamada Y. (Am. J. Hypertens. 2010) 3 46 64
  3. Association of genetic variants with hemorrhagic stroke in Japanese individuals. (PMID: 20198315) Yoshida T. … Yamada Y. (Int. J. Mol. Med. 2010) 3 46 64
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 64
  5. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3 64

Products for ZNF607 Gene

Sources for ZNF607 Gene

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