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Aliases for ZNF606 Gene

Aliases for ZNF606 Gene

  • Zinc Finger Protein 606 2 3
  • ZNF328 3 4 6
  • Zinc Finger Protein 328 3 4
  • KIAA1852 4 6

External Ids for ZNF606 Gene

Previous HGNC Symbols for ZNF606 Gene

  • ZNF328

Previous GeneCards Identifiers for ZNF606 Gene

  • GC19M063076
  • GC19M063181
  • GC19M058488
  • GC19M054799

Summaries for ZNF606 Gene

GeneCards Summary for ZNF606 Gene

ZNF606 (Zinc Finger Protein 606) is a Protein Coding gene. Among its related pathways are Gene Expression and Gene Expression. An important paralog of this gene is ZNF10.

UniProtKB/Swiss-Prot for ZNF606 Gene

  • May act as a transcriptional repressor.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF606 Gene

Genomics for ZNF606 Gene

Regulatory Elements for ZNF606 Gene

Genomic Location for ZNF606 Gene

Start:
57,977,053 bp from pter
End:
58,003,349 bp from pter
Size:
26,297 bases
Orientation:
Minus strand

Genomic View for ZNF606 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZNF606 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF606 Gene

Proteins for ZNF606 Gene

  • Protein details for ZNF606 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8WXB4-ZN606_HUMAN
    Recommended name:
    Zinc finger protein 606
    Protein Accession:
    Q8WXB4
    Secondary Accessions:
    • A8KAN2
    • Q8NE04
    • Q96JH5

    Protein attributes for ZNF606 Gene

    Size:
    792 amino acids
    Molecular mass:
    91812 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAB47481.1; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305};

neXtProt entry for ZNF606 Gene

Proteomics data for ZNF606 Gene at MOPED

Post-translational modifications for ZNF606 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF606 Gene

No data available for DME Specific Peptides for ZNF606 Gene

Domains for ZNF606 Gene

Gene Families for ZNF606 Gene

HGNC:
  • ZNF :Zinc fingers, C2H2-type

Suggested Antigen Peptide Sequences for ZNF606 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q8WXB4

UniProtKB/Swiss-Prot:

ZN606_HUMAN :
  • Q8WXB4
Domain:
  • Contains 1 KRAB domain.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 16 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF606: view

Function for ZNF606 Gene

Molecular function for ZNF606 Gene

UniProtKB/Swiss-Prot Function: May act as a transcriptional repressor.

Gene Ontology (GO) - Molecular Function for ZNF606 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding --
GO:0003677 DNA binding IEA --
GO:0003700 sequence-specific DNA binding transcription factor activity IBA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF606: view

Phenotypes for ZNF606 Gene

GenomeRNAi human phenotypes for ZNF606:
genes like me logo Genes that share phenotypes with ZNF606: view

miRNA for ZNF606 Gene

miRTarBase miRNAs that target ZNF606

No data available for Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for ZNF606 Gene

Localization for ZNF606 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF606 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF606 Gene COMPARTMENTS Subcellular localization image for ZNF606 gene
Compartment Confidence
nucleus 5
cytosol 3

Gene Ontology (GO) - Cellular Components for ZNF606 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular --
GO:0005634 nucleus --
GO:0005654 nucleoplasm IDA --
GO:0005737 cytoplasm IDA --
genes like me logo Genes that share ontologies with ZNF606: view

Pathways for ZNF606 Gene

SuperPathways for ZNF606 Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF606: view

Pathways by source for ZNF606 Gene

2 Reactome pathways for ZNF606 Gene

Interacting Proteins for ZNF606 Gene

Gene Ontology (GO) - Biological Process for ZNF606 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IBA --
genes like me logo Genes that share ontologies with ZNF606: view

Transcripts for ZNF606 Gene

Unigene Clusters for ZNF606 Gene

Zinc finger protein 606:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF606 Gene

No ASD Table

Relevant External Links for ZNF606 Gene

GeneLoc Exon Structure for
ZNF606
ECgene alternative splicing isoforms for
ZNF606

Expression for ZNF606 Gene

mRNA expression in normal human tissues for ZNF606 Gene

SOURCE GeneReport for Unigene cluster for ZNF606 Gene Hs.654967

mRNA Expression by UniProt/SwissProt for ZNF606 Gene

Q8WXB4-ZN606_HUMAN
Tissue specificity: Widely expressed in adult and fetal tissues.
genes like me logo Genes that share expressions with ZNF606: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and Protein expression for ZNF606 Gene

Orthologs for ZNF606 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZNF606 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF606 35
  • 99.62 (n)
  • 99.37 (a)
ZNF606 36
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia ZNF606 36
  • 91 (a)
OneToOne
dog
(Canis familiaris)
Mammalia ZNF606 35
  • 92.24 (n)
  • 93.92 (a)
ZNF606 36
  • 87 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Zfp606 35
  • 89.04 (n)
  • 89.63 (a)
Zfp606 16
Zfp606 36
  • 89 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Zfp606 35
  • 88.61 (n)
  • 88.52 (a)
lizard
(Anolis carolinensis)
Reptilia -- 36
  • 57 (a)
OneToMany
Species with no ortholog for ZNF606:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF606 Gene

ENSEMBL:
Gene Tree for ZNF606 (if available)
TreeFam:
Gene Tree for ZNF606 (if available)

Paralogs for ZNF606 Gene

Selected SIMAP similar genes for ZNF606 Gene using alignment to 8 proteins:

genes like me logo Genes that share paralogs with ZNF606: view

Variants for ZNF606 Gene

Sequence variations from dbSNP and Humsavar for ZNF606 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type MAF
rs525221 -- 57,978,019(-) GACTG(C/T)GGGGA utr-variant-3-prime
rs929832 -- 58,000,796(+) GCGAC(A/C)AAATA intron-variant
rs1035521 -- 57,999,514(+) GACAT(A/G)AGTGA intron-variant
rs1035522 -- 57,999,564(+) TGCCC(C/T)TCATG intron-variant
rs2375230 -- 57,993,727(+) AGACC(A/T)CTTCA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF606 Gene

Variant ID Type Subtype PubMed ID
nsv833885 CNV Loss 17160897
nsv516650 CNV Loss 19592680
nsv912533 CNV Loss 21882294

Relevant External Links for ZNF606 Gene

HapMap Linkage Disequilibrium report
ZNF606

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF606 Gene

Disorders for ZNF606 Gene

No disorders were found for ZNF606 Gene.

No data available for UniProtKB/Swiss-Prot for ZNF606 Gene

Publications for ZNF606 Gene

  1. Prediction of the coding sequences of unidentified human genes. XX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PMID: 11347906) Nagase T. … Ohara O. (DNA Res. 2001) 2 3 4
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  4. ZNF328, a novel human zinc-finger protein, suppresses transcriptional activities of SRE and AP-1. (PMID: 15964554) Ou Y. … Liu M. (Biochem. Biophys. Res. Commun. 2005) 3 4
  5. Toward a confocal subcellular atlas of the human proteome. (PMID: 18029348) Barbe L. … Andersson-Svahn H. (Mol. Cell Proteomics 2008) 3

Products for ZNF606 Gene

Sources for ZNF606 Gene

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