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Aliases for ZNF605 Gene

Aliases for ZNF605 Gene

  • Zinc Finger Protein 605 2 3
  • EC 2.5.1.18 63
  • EC 2.1.1.43 63

External Ids for ZNF605 Gene

Previous GeneCards Identifiers for ZNF605 Gene

  • GC12M131737
  • GC12M132108
  • GC12M132008
  • GC00U928747
  • GC12M133499
  • GC12M130274

Summaries for ZNF605 Gene

GeneCards Summary for ZNF605 Gene

ZNF605 (Zinc Finger Protein 605) is a Protein Coding gene. An important paralog of this gene is ZNF630.

UniProtKB/Swiss-Prot for ZNF605 Gene

  • May be involved in transcriptional regulation

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF605 Gene

Genomics for ZNF605 Gene

Genomic Location for ZNF605 Gene

Start:
132,918,308 bp from pter
End:
132,956,306 bp from pter
Size:
37,999 bases
Orientation:
Minus strand

Genomic View for ZNF605 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZNF605 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF605 Gene

No data available for Regulatory Elements for ZNF605 Gene

Proteins for ZNF605 Gene

  • Protein details for ZNF605 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q86T29-ZN605_HUMAN
    Recommended name:
    Zinc finger protein 605
    Protein Accession:
    Q86T29
    Secondary Accessions:
    • B3KVG4
    • D3DXJ0
    • Q86T91

    Protein attributes for ZNF605 Gene

    Size:
    641 amino acids
    Molecular mass:
    74376 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ZNF605 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZNF605 Gene

Proteomics data for ZNF605 Gene at MOPED

Selected DME Specific Peptides for ZNF605 Gene

Post-translational modifications for ZNF605 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF605 Gene

ENSEMBL proteins:
Reactome Protein details:
REFSEQ proteins:

Domains for ZNF605 Gene

Gene Families for ZNF605 Gene

HGNC:
  • ZNF :Zinc fingers, C2H2-type

Graphical View of Domain Structure for InterPro Entry

Q86T29

UniProtKB/Swiss-Prot:

ZN605_HUMAN :
  • Q86T29
Domain:
  • Contains 1 KRAB domain.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 17 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF605: view

Function for ZNF605 Gene

Molecular function for ZNF605 Gene

UniProtKB/Swiss-Prot Function: May be involved in transcriptional regulation

Enzyme Numbers (IUBMB) for ZNF605 Gene

Gene Ontology (GO) - Molecular Function for ZNF605 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding --
GO:0003677 DNA binding IEA --
GO:0003700 sequence-specific DNA binding transcription factor activity IBA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF605: view

Animal Model Products

CRISPR Products

miRNA for ZNF605 Gene

miRTarBase miRNAs that target ZNF605

No data available for Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for ZNF605 Gene

Localization for ZNF605 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF605 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF605 Gene COMPARTMENTS Subcellular localization image for ZNF605 gene
Compartment Confidence
nucleus 4
cytosol 2

Gene Ontology (GO) - Cellular Components for ZNF605 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF605: view

Pathways for ZNF605 Gene

SuperPathways for ZNF605 Gene

No Data Available

Interacting Proteins for ZNF605 Gene

Gene Ontology (GO) - Biological Process for ZNF605 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IBA --
genes like me logo Genes that share ontologies with ZNF605: view

No data available for Pathways by source for ZNF605 Gene

Transcripts for ZNF605 Gene

mRNA/cDNA for ZNF605 Gene

(6) Additional mRNA sequences :
(2) REFSEQ mRNAs :
(6) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ZNF605 Gene

Zinc finger protein 605:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZNF605

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF605 Gene

ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5a · 5b ^ 6
SP1: -
SP2:
SP3: -

Relevant External Links for ZNF605 Gene

GeneLoc Exon Structure for
ZNF605
ECgene alternative splicing isoforms for
ZNF605

Expression for ZNF605 Gene

mRNA expression in normal human tissues for ZNF605 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for ZNF605 Gene

SOURCE GeneReport for Unigene cluster for ZNF605 Gene Hs.29698

genes like me logo Genes that share expressions with ZNF605: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ZNF605 Gene

Orthologs for ZNF605 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF605 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF605 35
  • 99.06 (n)
  • 98.81 (a)
ZNF605 36
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia ZNF605 35
  • 86.71 (n)
  • 84.97 (a)
ZNF605 36
  • 83 (a)
OneToOne
dog
(Canis familiaris)
Mammalia ZNF605 35
  • 86.92 (n)
  • 86.42 (a)
ZNF605 36
  • 85 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Zfp605 35
  • 76.05 (n)
  • 63.1 (a)
Zfp605 16
Zfp605 36
  • 60 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia LOC100365779 35
  • 72.48 (n)
  • 61.2 (a)
Species with no ortholog for ZNF605:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF605 Gene

ENSEMBL:
Gene Tree for ZNF605 (if available)
TreeFam:
Gene Tree for ZNF605 (if available)

Paralogs for ZNF605 Gene

Selected SIMAP similar genes for ZNF605 Gene using alignment to 2 proteins:

Pseudogenes.org Pseudogenes for ZNF605 Gene

genes like me logo Genes that share paralogs with ZNF605: view

Variants for ZNF605 Gene

Sequence variations from dbSNP and Humsavar for ZNF605 Gene

SNP ID Clin Chr 12 pos Sequence Context AA Info Type MAF
rs2933 -- 132,942,252(+) TAAAA(A/G)CTTTC intron-variant
rs7778 -- 132,921,772(-) TTTGA(A/C)GGGAA utr-variant-3-prime
rs10357 -- 132,924,025(-) tttta(A/C)tggcc utr-variant-3-prime
rs12772 -- 132,921,910(+) TTCAA(C/T)TTAAT utr-variant-3-prime
rs13273 -- 132,921,758(-) ATTGC(C/T)GTTAG utr-variant-3-prime

Structural Variations from Database of Genomic Variants (DGV) for ZNF605 Gene

Variant ID Type Subtype PubMed ID
dgv538e1 CNV Complex 17122850
nsv470335 CNV Loss 18288195
esv22416 CNV Loss 19812545
dgv330e199 CNV Deletion 23128226
nsv945 CNV Insertion 18451855
dgv331e199 CNV Deletion 23128226
nsv509495 CNV Insertion 20534489
nsv9046 CNV Gain 18304495
nsv528637 CNV Loss 19592680
esv1007810 CNV Insertion 20482838
nsv899834 CNV Gain 21882294

Relevant External Links for ZNF605 Gene

HapMap Linkage Disequilibrium report
ZNF605

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF605 Gene

Disorders for ZNF605 Gene

Relevant External Links for ZNF605

Genetic Association Database (GAD)
ZNF605
genes like me logo Genes that share disorders with ZNF605: view

No data available for UniProtKB/Swiss-Prot for ZNF605 Gene

Publications for ZNF605 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  2. The full-ORF clone resource of the German cDNA consortium. (PMID: 17974005) Bechtel S. … Schupp I. (BMC Genomics 2007) 3 4
  3. The finished DNA sequence of human chromosome 12. (PMID: 16541075) Scherer S.E. … Gibbs R.A. (Nature 2006) 4
  4. The sequence of the human genome. (PMID: 11181995) Venter J.C. … Zhu X. (Science 2001) 3
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for ZNF605 Gene

Sources for ZNF605 Gene

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