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Aliases for ZNF600 Gene

Aliases for ZNF600 Gene

  • Zinc Finger Protein 600 2 3
  • Zinc Finger Protein KR-ZNF1 3
  • KR-ZNF1 3

External Ids for ZNF600 Gene

Previous GeneCards Identifiers for ZNF600 Gene

  • GC19M057959
  • GC19M057948
  • GC19M053267
  • GC19M049596

Summaries for ZNF600 Gene

GeneCards Summary for ZNF600 Gene

ZNF600 (Zinc Finger Protein 600) is a Protein Coding gene. Among its related pathways are Gene Expression and Gene Expression. An important paralog of this gene is ZNF860.

UniProtKB/Swiss-Prot for ZNF600 Gene

  • May be involved in transcriptional regulation

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF600 Gene

Genomics for ZNF600 Gene

Regulatory Elements for ZNF600 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for ZNF600 Gene

Start:
52,764,195 bp from pter
End:
52,833,622 bp from pter
Size:
69,428 bases
Orientation:
Minus strand

Genomic View for ZNF600 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZNF600 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF600 Gene

Proteins for ZNF600 Gene

  • Protein details for ZNF600 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6ZNG1-ZN600_HUMAN
    Recommended name:
    Zinc finger protein 600
    Protein Accession:
    Q6ZNG1
    Secondary Accessions:
    • Q6MZR0

    Protein attributes for ZNF600 Gene

    Size:
    722 amino acids
    Molecular mass:
    83124 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZNF600 Gene

Proteomics data for ZNF600 Gene at MOPED

Post-translational modifications for ZNF600 Gene

  • Ubiquitination at Lys695
  • Modification sites at PhosphoSitePlus

Other Protein References for ZNF600 Gene

ENSEMBL proteins:
Reactome Protein details:
REFSEQ proteins:

No data available for DME Specific Peptides for ZNF600 Gene

Domains for ZNF600 Gene

Gene Families for ZNF600 Gene

HGNC:
  • ZNF :Zinc fingers, C2H2-type

Protein Domains for ZNF600 Gene

Suggested Antigen Peptide Sequences for ZNF600 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q6ZNG1

UniProtKB/Swiss-Prot:

ZN600_HUMAN :
  • Q6ZNG1
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 20 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF600: view

Function for ZNF600 Gene

Molecular function for ZNF600 Gene

UniProtKB/Swiss-Prot Function: May be involved in transcriptional regulation

Gene Ontology (GO) - Molecular Function for ZNF600 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding --
GO:0003677 DNA binding IEA --
GO:0003700 sequence-specific DNA binding transcription factor activity IBA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF600: view

Phenotypes for ZNF600 Gene

GenomeRNAi human phenotypes for ZNF600:
genes like me logo Genes that share phenotypes with ZNF600: view

Animal Model Products

CRISPR Products

miRNA for ZNF600 Gene

miRTarBase miRNAs that target ZNF600

No data available for Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for ZNF600 Gene

Localization for ZNF600 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF600 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF600 Gene COMPARTMENTS Subcellular localization image for ZNF600 gene
Compartment Confidence
nucleus 4
cytosol 2

Gene Ontology (GO) - Cellular Components for ZNF600 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF600: view

Pathways for ZNF600 Gene

SuperPathways for ZNF600 Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF600: view

Pathways by source for ZNF600 Gene

2 Reactome pathways for ZNF600 Gene

Gene Ontology (GO) - Biological Process for ZNF600 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IBA --
genes like me logo Genes that share ontologies with ZNF600: view

Transcripts for ZNF600 Gene

Unigene Clusters for ZNF600 Gene

Zinc finger protein 600:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZNF600

Primer Products

  • OriGene qSTAR qPCR primer pairs in human,mouse,rat for ZNF600
  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF600 Gene

ExUns: 1a · 1b · 1c ^ 2a · 2b ^ 3a · 3b ^ 4 ^ 5
SP1: - - - -
SP2: -
SP3: - -
SP4:

Relevant External Links for ZNF600 Gene

GeneLoc Exon Structure for
ZNF600
ECgene alternative splicing isoforms for
ZNF600

Expression for ZNF600 Gene

mRNA expression in normal human tissues for ZNF600 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for ZNF600 Gene

SOURCE GeneReport for Unigene cluster for ZNF600 Gene Hs.696848

genes like me logo Genes that share expressions with ZNF600: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ZNF600 Gene

Orthologs for ZNF600 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF600 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF600 35
  • 96.08 (n)
  • 95.43 (a)
ZNF600 36
  • 98 (a)
OneToOne
cow
(Bos Taurus)
Mammalia -- 36
  • 43 (a)
ManyToMany
dog
(Canis familiaris)
Mammalia -- 36
  • 43 (a)
ManyToMany
Species with no ortholog for ZNF600:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF600 Gene

ENSEMBL:
Gene Tree for ZNF600 (if available)
TreeFam:
Gene Tree for ZNF600 (if available)

Paralogs for ZNF600 Gene

Selected SIMAP similar genes for ZNF600 Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with ZNF600: view

Variants for ZNF600 Gene

Sequence variations from dbSNP and Humsavar for ZNF600 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type MAF
rs3815 -- 52,793,924(+) TCAAA(A/T)ACATG intron-variant
rs1559237 -- 52,786,852(-) GTCTC(C/T)CCGCC upstream-variant-2KB, intron-variant
rs1559238 -- 52,786,834(-) CCGCC(C/T)CTACC upstream-variant-2KB, intron-variant
rs1559239 -- 52,786,722(-) AGTTT(C/T)GCTCT utr-variant-5-prime, intron-variant
rs1820128 - 52,767,131(+) TCTAC(A/G)ATGGC missense, reference

Structural Variations from Database of Genomic Variants (DGV) for ZNF600 Gene

Variant ID Type Subtype PubMed ID
esv2718786 CNV Deletion 23290073
esv2718787 CNV Deletion 23290073
dgv3980n71 CNV Gain 21882294
dgv3981n71 CNV Gain 21882294
nsv509752 CNV Insertion 20534489
esv2718796 CNV Deletion 23290073
dgv3984n71 CNV Gain 21882294
nsv458745 CNV Gain 19166990
nsv833875 CNV Loss 17160897
esv2671531 CNV Deletion 23128226
nsv527597 CNV Loss 19592680
esv2664794 CNV Deletion 23128226
esv2718798 CNV Deletion 23290073
nsv458746 CNV Gain 19166990

Relevant External Links for ZNF600 Gene

HapMap Linkage Disequilibrium report
ZNF600
Human Gene Mutation Database (HGMD)
ZNF600

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF600 Gene

Disorders for ZNF600 Gene

Relevant External Links for ZNF600

Genetic Association Database (GAD)
ZNF600
genes like me logo Genes that share disorders with ZNF600: view

No data available for UniProtKB/Swiss-Prot for ZNF600 Gene

Publications for ZNF600 Gene

  1. Regulation of T-cell receptor D beta 1 promoter by KLF5 through reiterated GC-rich motifs. (PMID: 12576331) Yang X.O. … Willerford D.M. (Blood 2003) 2 3
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. Genome-wide association study identifies novel loci associated with circulating phospho- and sphingolipid concentrations. (PMID: 22359512) Demirkan A. … Schmitz G. (PLoS Genet. 2012) 3 48
  4. Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition. (PMID: 22505724) Udeshi N.D. … Carr S.A. (Mol. Cell Proteomics 2012) 3
  5. Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. (PMID: 23000965) Povlsen L.K. … Choudhary C. (Nat. Cell Biol. 2012) 3

Products for ZNF600 Gene

Sources for ZNF600 Gene

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