ZNF600 Gene
protein-coding GIFtS: 44
GCID: GC19M053267
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|
zinc finger protein 600
| |
Aliases
for ZNF600 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Zinc Finger Protein 6001 2 | | KR-ZNF11 2 | | DKFZp686F061231 | | Zinc Finger Protein KR-ZNF12 |
Export aliases for ZNF600 gene to outside databasesPrevious GC identifers: GC19M057959 GC19M057948 GC19M049596 |
Summaries
for ZNF600 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
UniProtKB/Swiss-Prot: ZN600_HUMAN, Q6ZNG1Function: May be involved in transcriptional regulation
|
Genomic Views
for ZNF600 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000019.9 NC_018930.1 NT_011109.16
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the ZNF600 gene promoter:
NF-AT4 NF-AT2 NF-AT3 Nkx2-5 NF-AT1 NF-AT
Other transcription factors
Search SABiosciences Chromatin IP Primers for ZNF600
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZNF600 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 19q13.41 Ensembl cytogenetic band: 19q13.41 HGNC cytogenetic band: 19q13.42ZNF600 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 19 GeneLoc Exon Structure GeneLoc location for GC19M053267: view genomic region
(about GC identifiers)
Start:
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53,268,747 bp from pter |
End:
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53,290,034 bp from pter |
Size:
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21,288 bases |
Orientation:
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minus strand |
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Proteins
for ZNF600 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: ZN600_HUMAN, Q6ZNG1 (See
protein sequence)Recommended Name: Zinc finger protein 600 Size: 722 amino acids; 83124 Da
Subcellular location: Nucleus (Probable)
Secondary accessions: Q6MZR0Explore the universe of human proteins at neXtProt for ZNF600: NX_Q6ZNG1
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q6ZNG1
ZNF600 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_940859.2
ENSEMBL proteins: ENSP00000344791 Reactome Protein details: Q6ZNG1
Human Recombinant Protein Products:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005634 | nucleus |
IEA | -- |
ZNF600 for ontologies About GeneDecksing
ZNF600 Antibody Products:
Assay Products for ZNF600: |
Protein
Domains /
Families
for ZNF600 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ZNF600 for domains About GeneDecksing
3 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q6ZNG1ProtoNet protein and cluster: Q6ZNG1 UniProtKB/Swiss-Prot: ZN600_HUMAN, Q6ZNG1Similarity: Belongs to the krueppel C2H2-type zinc-finger protein familySimilarity: Contains 20 C2H2-type zinc fingers |
Function
for ZNF600 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: ZN600_HUMAN, Q6ZNG1Function: May be involved in transcriptional regulation
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF600
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF600
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: ZNF600 (NM_198457) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ZNF600 | |  | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat ZNF600 |
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table
ZNF600 for ontologies About GeneDecksing
1 GenomeRNAi human phenotype for ZNF600:
|
Pathways & Interactions
for ZNF600 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Generic Transcription Pathway | |
Pathway sources
See GeneCards unified pathways
Show all pathways
2 
Reactome Pathways for ZNF600
ZNF600 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ZNF600
STRING Interaction
Network Preview (showing 1 interactants - click image to see more details)
1 Interacting protein for ZNF600 (Q6ZNG13 ENSP000003447914) via UniProtKB, MINT, STRING, and/or I2DAbout this table
Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006351 | transcription, DNA-dependent |
IEA | -- | | GO:0006355 | regulation of transcription, DNA-dependent |
IEA | -- |
ZNF600 for ontologies About GeneDecksing
|
Drugs & Compounds
for ZNF600 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for ZNF600
Search CenterWatch for drugs/clinical trials and news about ZNF600 / ZN600
|
Transcripts
for ZNF600 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for ZNF600 gene: NM_198457.2 Unigene Cluster for ZNF600: Zinc finger protein 600 Hs.696848 [show with all ESTs]Unigene Representative Sequence: BX6409331 Ensembl transcript including schematic representation, and UCSC links where relevant: ENST00000338230(uc002qab.4)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF600
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF600
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: ZNF600 (NM_198457) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ZNF600 | | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat ZNF600 |
Additional cDNA sequence: AK075230.1 AK131231.1 BX640933.1 U52096.1 8 DOTS entries: DT.95214051 DT.100797473 DT.91694659 DT.95207791 DT.86837062 DT.40130033 DT.91690191 DT.92417082 24/70 AceView cDNA sequences (see all 70): BQ958705 AI003260 CD244192 BQ690668 BQ008299 BC067346 BP871716 AI953831 BV199062 BQ060959 BQ023016 CF595699 BQ685199 CO245168 BG324525 AL833487 BQ016962 NM_018260 BV198598 AK055946 AK001753 BC080612 CR749856 BV193457
GeneLoc Exon Structure
4 Alternative Splicing Database (ASD) splice patterns (SP) for ZNF600 About this scheme
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2a | · | 2b | ^ | 3a | · | 3b | ^ | 4 | ^ | 5 |
|---|
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| SP1: | | | | | | | - | | - | | - | | - | | | | | | |
| SP2: | | | | | | | | | - | | | | | | | | | | |
| SP3: | | | | | | | - | | - | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for ZNF600
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Expression
for ZNF600 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ZNF600 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GTGTAGGGAA
About this image
See ZNF600 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for ZNF600
SOURCE GeneReport for Unigene cluster: Hs.696848
SABiosciences Custom PCR Arrays for ZNF600
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZNF600
Browse OriGene validated miRNA SYBR primer pairs
| | | Search SABiosciences RT2 qPCR
Primer Assays in human, mouse, rat ZNF600 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZNF600 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZNF600 |
Orthologs
for ZNF600 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
--
ENSEMBL Gene Tree for ZNF600 (if available)
TreeFam Gene Tree for ZNF600 (if available) |
Paralogs
for ZNF600 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for ZNF600 gene
- ZNF5342 ZNF321P2 ZNF4682 ZNF5782 ZNF8802 ZNF7662 ZNF3202 ZNF5252
- ZNF8602 ZNF4152 ZNF282 ZNF5282 ZNF6112 ZNF6772 ZNF832 ZNF8162
- ZNF6102 ZNF7012 ZNF7652 ZNF4802 ZNF8132
18/626 SIMAP similar genes for ZNF600 using alignment to 2 protein entries: ZN600_HUMAN (see all proteins)
(see all similar genes):ZNF611 ZNF321P kr-znf3 ZNF28 ZNF578 ZNF701
ZNF845 ZFS-1 ZNF883 DKFZp686G16228 ZFS-5 ZNF813
ZSCAN16 ZNF3 DKFZp666C237 ZNF468 ZNF765 ZNF78L1
ZNF600 for paralogs About GeneDecksing
|
Genomic Variants
for ZNF600 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 19 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for ZNF600 (53268747 - 53290034 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for ZNF600: --
Human Gene Mutation Database (HGMD): ZNF600
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ZNF600 |
|
Disorders
/ Diseases
for ZNF600 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
 ZNF600 for disorders About MalaCards
ZNF600 for disorders About GeneDecksing
Export disorders for ZNF600 gene to outside databases
|
Publications
for ZNF600 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ZNF600 gene integrated from 9 sources:
(articles sorted by number of sources associating them with ZNF600) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Regulation of T-cell receptor D beta 1 promoter by KLF5 through reiterated GC-rich motifs. (PubMed id 12576331)1, 3 Yang X.O.... Willerford D.M. (2003)
- Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)
- Genome-wide association study identifies novel loci as sociated with circulating phospho- and sphingolipid concentrations. (PubMed id 22359512)1 Demirkan A....Schmitz G. (2012)
- A human MAP kinase interactome. (PubMed id 20936779)1 Bandyopadhyay S....Ideker T. (2010)
- Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions. (PubMed id 19690332)2 Mayya V.... Han D.K. (2009)
- The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (2007)
- The DNA sequence and biology of human chromosome 19. (PubMed id 15057824)2 Grimwood J.... Lucas S.M. (2004)
|
External Searches for ZNF600 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing ZNF600 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing ZNF600 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing ZNF600 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for ZNF600 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for ZNF600 gene:
Search GeneIP for patents involving ZNF600
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for ZNF600 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for ZNF600 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ZNF600 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZNF600 | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for ZNF600 | | OriGene 3'-UTR Clone for ZNF600 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF600 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF600 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for ZNF600 | | OriGene Custom Protein Services for ZNF600 | | | OriGene Custom Immunoassay Development | | |
| |
 |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ZNF600 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ZNF600 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZNF600 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ZNF600 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZNF600 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZNF600 |
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 |  |  |  | |
| | | | Search Tocris compounds for ZNF600 |
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 | | | ZNF600 Proteins, Antibodies, CLIAs, and ELISAs |
| | | |  |  |  | | | | Search ThermoFisher Antibodies for ZNF600 |
| | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat ZNF600 |
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