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Aliases for ZNF597 Gene

Aliases for ZNF597 Gene

  • Zinc Finger Protein 597 2 3
  • HIT-4 3

External Ids for ZNF597 Gene

Previous GeneCards Identifiers for ZNF597 Gene

  • GC16M003487
  • GC16M003426
  • GC16M003488

Summaries for ZNF597 Gene

GeneCards Summary for ZNF597 Gene

ZNF597 (Zinc Finger Protein 597) is a Protein Coding gene. Among its related pathways are Gene Expression and Gene Expression. An important paralog of this gene is ZNF200.

UniProtKB/Swiss-Prot for ZNF597 Gene

  • May be involved in transcriptional regulation

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF597 Gene

Genomics for ZNF597 Gene

Regulatory Elements for ZNF597 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for ZNF597 Gene

3,432,422 bp from pter
3,443,542 bp from pter
11,121 bases
Minus strand

Genomic View for ZNF597 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZNF597 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF597 Gene

Proteins for ZNF597 Gene

  • Protein details for ZNF597 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Zinc finger protein 597
    Protein Accession:
    Secondary Accessions:

    Protein attributes for ZNF597 Gene

    424 amino acids
    Molecular mass:
    48076 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZNF597 Gene

Proteomics data for ZNF597 Gene at MOPED

Post-translational modifications for ZNF597 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF597 Gene

ENSEMBL proteins:
Reactome Protein details:
REFSEQ proteins:

Antibody Products

No data available for DME Specific Peptides for ZNF597 Gene

Domains for ZNF597 Gene

Gene Families for ZNF597 Gene

  • ZNF :Zinc fingers, C2H2-type

Protein Domains for ZNF597 Gene

Suggested Antigen Peptide Sequences for ZNF597 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Q96LX8
  • Contains 1 KRAB domain.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 7 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF597: view

Function for ZNF597 Gene

Molecular function for ZNF597 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation
UniProtKB/Swiss-Prot Induction:
Imprinted. Promoter methylation of the paternal allele may restrict expression to the maternal allele in leukocytes.

Gene Ontology (GO) - Molecular Function for ZNF597 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding --
GO:0003677 DNA binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF597: view

Phenotypes for ZNF597 Gene

GenomeRNAi human phenotypes for ZNF597:
genes like me logo Genes that share phenotypes with ZNF597: view

Animal Model Products

CRISPR Products

miRNA for ZNF597 Gene

miRTarBase miRNAs that target ZNF597

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZNF597

In Situ Assay Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for ZNF597 Gene

Localization for ZNF597 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF597 Gene

Subcellular locations from

Jensen Localization Image for ZNF597 Gene COMPARTMENTS Subcellular localization image for ZNF597 gene
Compartment Confidence
nucleus 3
cytosol 2

Gene Ontology (GO) - Cellular Components for ZNF597 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF597: view

Pathways for ZNF597 Gene

SuperPathways for ZNF597 Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF597: view

Pathways by source for ZNF597 Gene

2 Reactome pathways for ZNF597 Gene

Interacting Proteins for ZNF597 Gene

Gene Ontology (GO) - Biological Process for ZNF597 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF597: view

Transcripts for ZNF597 Gene

mRNA/cDNA for ZNF597 Gene

(27) Selected AceView cDNA sequences:
(2) Additional mRNA sequences :
(1) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ZNF597 Gene

Zinc finger protein 597:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZNF597

Primer Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF597 Gene

No ASD Table

Relevant External Links for ZNF597 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ZNF597 Gene

mRNA expression in normal human tissues for ZNF597 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for ZNF597 Gene

SOURCE GeneReport for Unigene cluster for ZNF597 Gene Hs.88630

genes like me logo Genes that share expressions with ZNF597: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Expression partners for ZNF597 Gene

Orthologs for ZNF597 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZNF597 Gene

Organism Taxonomy Gene Similarity Type Details
(Canis familiaris)
Mammalia ZNF597 35
  • 80.87 (n)
  • 68.1 (a)
ZNF597 36
  • 68 (a)
(Mus musculus)
Mammalia Zfp597 35
  • 76 (n)
  • 63.64 (a)
Zfp597 16
Zfp597 36
  • 63 (a)
(Pan troglodytes)
Mammalia ZNF597 35
  • 98.82 (n)
  • 98.11 (a)
ZNF597 36
  • 98 (a)
(Rattus norvegicus)
Mammalia Zfp597 35
  • 74.82 (n)
  • 62.35 (a)
(Bos Taurus)
Mammalia ZNF597 36
  • 57 (a)
(Monodelphis domestica)
Mammalia ZNF597 36
  • 32 (a)
(Danio rerio)
Actinopterygii CR352258.1 36
  • 30 (a)
Species with no ortholog for ZNF597:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ZNF597 Gene

Gene Tree for ZNF597 (if available)
Gene Tree for ZNF597 (if available)

Paralogs for ZNF597 Gene

Paralogs for ZNF597 Gene

Selected SIMAP similar genes for ZNF597 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with ZNF597: view

Variants for ZNF597 Gene

Sequence variations from dbSNP and Humsavar for ZNF597 Gene

SNP ID Clin Chr 16 pos Sequence Context AA Info Type MAF
rs37824 -- 3,436,236(+) TGACA(C/T)GGATT utr-variant-3-prime
rs37825 -- 3,437,576(+) GACAA(C/T)ATCTT intron-variant
rs37826 -- 3,438,334(+) gcggg(C/T)ggatc intron-variant
rs37827 -- 3,438,357(+) gatca(A/G)gacca intron-variant
rs37828 -- 3,438,569(+) aaaaa(A/T)aataa intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF597 Gene

Variant ID Type Subtype PubMed ID
nsv905212 CNV Gain 21882294
esv29492 CNV Gain 19812545

Relevant External Links for ZNF597 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF597 Gene

Disorders for ZNF597 Gene

(1) University of Copenhagen DISEASES for ZNF597 Gene

genes like me logo Genes that share disorders with ZNF597: view

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , Novoseek inferred disease relationships , Genatlas and External Links for ZNF597 Gene

Publications for ZNF597 Gene

  1. Molecular characterization and gene disruption of a novel zinc-finger protein, HIT-4, expressed in rodent brain. (PMID: 19968752) Tanabe Y. … Nawa H. (J. Neurochem. 2010) 2 3
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  4. Toward a confocal subcellular atlas of the human proteome. (PMID: 18029348) Barbe L. … Andersson-Svahn H. (Mol. Cell Proteomics 2008) 3
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for ZNF597 Gene

Sources for ZNF597 Gene

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