Aliases for ZNF589 Gene
Aliases for ZNF589 Gene
External Ids for ZNF589 Gene
- HGNC: 16747
- Entrez Gene: 51385
- Ensembl: ENSG00000164048
- OMIM: 616702
- UniProtKB: Q86UQ0
Previous GeneCards Identifiers for ZNF589 Gene
- GC03P048244
- GC03P048257
- GC03P048282
Summaries for ZNF589 Gene
GeneCards Summary for ZNF589 Gene
ZNF589 (Zinc Finger Protein 589) is a Protein Coding gene. Diseases associated with ZNF589 include Kleefstra Syndrome. Among its related pathways are Gene Expression. GO annotations related to this gene include nucleic acid binding. An important paralog of this gene is ZNF169.
UniProtKB/Swiss-Prot for ZNF589 Gene
-
May play a role in hematopoietic stem/progenitor cell differentiation. May play a role as a DNA binding-dependent transcriptional repressor.
No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF589 Gene
Genomics for ZNF589 Gene
Regulatory Elements for ZNF589 Gene
Enhancers for ZNF589 Gene
| GeneHancer Identifier | Score | Enhancer Sources | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites within enhancer | Other Gene Targets for Enhancer |
|---|
Enhancers around ZNF589 on UCSC Golden Path with GeneCards custom track
Promoters for ZNF589 Gene
| Ensembl Regulatory Elements (ENSRs) | TSS Distance (bp) | Size (bp) | Binding Sites for Transcription Factors within promoters |
|---|
ENSRs around ZNF589 on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Location for ZNF589 Gene
- Chromosome:
- 3
- Start:
- 48,241,100 bp from pter
- End:
- 48,299,253 bp from pter
- Size:
- 58,154 bases
- Orientation:
- Plus strand
Genomic View for ZNF589 Gene
Genes around ZNF589 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 3p21.31 by Ensembl
- 3p21 by Entrez Gene
- 3p21 by HGNC
ZNF589 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for ZNF589 Gene
Proteins for ZNF589 Gene
-
Protein details for ZNF589 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q86UQ0-ZN589_HUMAN
- Recommended name:
- Zinc finger protein 589
- Protein Accession:
- Q86UQ0
- Q86UC9
- Q9BRI6
- Q9BRY3
- Q9Y611
- Q9Y612
Protein attributes for ZNF589 Gene
- Size:
- 364 amino acids
- Molecular mass:
- 41189 Da
- Quaternary structure:
-
- Interacts with TRIM28.
- SequenceCaution:
-
- Sequence=AAH05859.2; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=AAH06247.2; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=AAH48798.1; Type=Erroneous initiation; Evidence={ECO:0000305};
Protein Expression for ZNF589 Gene
Selected DME Specific Peptides for ZNF589 Gene
Post-translational modifications for ZNF589 Gene
Other Protein References for ZNF589 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Novus Biologicals Antibodies for ZNF589
- Abcam antibodies for ZNF589
- antibodies-online Antibodies for ZNF589: See all 24
- Search GeneTex for Antibodies for ZNF589
-
Santa Cruz Biotechnology (SCBT) Antibodies for ZNF589
Protein Products
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for ZNF589
- Origene Custom Protein Services for ZNF589
- Novus Biologicals proteins for ZNF589
- Search GeneTex for Proteins for ZNF589
Assay Products
Domains & Families for ZNF589 Gene
Gene Families for ZNF589 Gene
Protein Domains for ZNF589 Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for ZNF589 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
Q86UQ0UniProtKB/Swiss-Prot:
ZN589_HUMAN :- The KRAB domain mediates interaction with TRIM28.
- Belongs to the krueppel C2H2-type zinc-finger protein family.
- Contains 4 C2H2-type zinc fingers.
- Domain:
-
- The KRAB domain mediates interaction with TRIM28.
- Contains 1 KRAB domain.
- Family:
-
- Belongs to the krueppel C2H2-type zinc-finger protein family.
- Similarity:
-
- Contains 4 C2H2-type zinc fingers.
Function for ZNF589 Gene
Molecular function for ZNF589 Gene
- UniProtKB/Swiss-Prot Function:
- May play a role in hematopoietic stem/progenitor cell differentiation. May play a role as a DNA binding-dependent transcriptional repressor.
Enzyme Numbers (IUBMB) for ZNF589 Gene
- EC 2.1.1.43 63
Phenotypes for ZNF589 Gene
- GenomeRNAi human phenotypes for ZNF589:
-
- Increased vaccinia virus (VACV) infection
- Increased gamma-H2AX phosphorylation
- Decreased hepcidin::fluc mRNA expression
- shRNA abundance <= 50%
- Mildly decreased CFP-tsO45G cell surface transport
- Decreased viability in esophageal squamous lineage
- Decreased NF-kappaB reporter expression
- Decreased shRNA abundance
- Decreased viability with TRAIL
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
-
ViGene Biosciences lentiviral particle packaged cDNA for ZNF589 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for ZNF589 gene
- Search ViGene Biosciences for ZNF589
CRISPR Products
-
OriGene CRISPR knockouts for ZNF589
-
Santa Cruz Biotechnology (SCBT) CRISPR for ZNF589
- GenScript: Design CRISPR guide RNA sequences for ZNF589
miRNA for ZNF589 Gene
- miRTarBase miRNAs that target ZNF589
-
- hsa-mir-30b-5p (MIRT046155)
- hsa-mir-1273e (MIRT453194)
- hsa-mir-139-3p (MIRT453195)
- hsa-mir-298 (MIRT453196)
- hsa-mir-1827 (MIRT453197)
- hsa-mir-219b-3p (MIRT453198)
- hsa-mir-4649-3p (MIRT453199)
- hsa-mir-6840-3p (MIRT453200)
- hsa-mir-4768-3p (MIRT453201)
- hsa-mir-665 (MIRT453202)
- hsa-mir-6511a-5p (MIRT453203)
- hsa-mir-1910-3p (MIRT453204)
- hsa-mir-302f (MIRT453205)
- hsa-mir-4724-3p (MIRT543655)
- hsa-mir-6849-3p (MIRT543656)
- hsa-mir-4999-3p (MIRT543657)
- hsa-mir-4461 (MIRT543658)
- hsa-mir-3680-5p (MIRT543659)
- hsa-mir-7849-3p (MIRT543660)
- hsa-mir-6750-3p (MIRT543661)
- hsa-mir-6771-5p (MIRT690782)
- hsa-mir-7977 (MIRT690783)
- hsa-mir-7160-5p (MIRT690784)
- hsa-mir-6884-5p (MIRT690785)
- hsa-mir-485-5p (MIRT690786)
- hsa-mir-6746-5p (MIRT690787)
- hsa-mir-5690 (MIRT690788)
- hsa-mir-4478 (MIRT690789)
- hsa-mir-4419b (MIRT690790)
- hsa-mir-3929 (MIRT690791)
miRNA Products
- Search ViGene Biosciences for ZNF589
Inhibitory RNA Products
- Origene RNAi, shRNA, and siRNA products in human, mouse, rat for ZNF589
- Browse OriGene Inhibitory RNA Products For ZNF589
-
ViGene Biosciences ready-to-package AAV shRNAs for ZNF589 gene
Clone Products
- OriGene clones in human for ZNF589
- OriGene ORF clones in human for ZNF589
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
Cell Line Products
-
ViGene Biosciences adenoviral particle packaged cDNA for ZNF589 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for ZNF589 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for ZNF589 gene
Flow Cytometry Products
No data available for Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF589 Gene
Localization for ZNF589 Gene
Subcellular locations from UniProtKB/Swiss-Prot for ZNF589 Gene
- Nucleus.
| Compartment | Confidence |
|---|---|
| nucleus | 5 |
| cytosol | 2 |
No data available for Gene Ontology (GO) - Cellular Components for ZNF589 Gene
Pathways & Interactions for ZNF589 Gene
More details on SuperPathways for ZNF589| Superpath | Contained pathways | ||
|---|---|---|---|
| 1 | Gene Expression |
.49
|
Pathways by source for ZNF589 Gene
2 Reactome pathways for ZNF589 Gene
Interacting Proteins for ZNF589 Gene
No data available for SIGNOR curated interactions for ZNF589 Gene
Transcripts for ZNF589 Gene
mRNA/cDNA for ZNF589 Gene
- (1) REFSEQ mRNAs :
- (10) Additional mRNA sequences :
- (79) Selected AceView cDNA sequences:
- (7) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for ZNF589 Gene
CRISPR Products
-
OriGene CRISPR knockouts for ZNF589
-
Santa Cruz Biotechnology (SCBT) CRISPR for ZNF589
- GenScript: Design CRISPR guide RNA sequences for ZNF589
miRNA Products
- Search ViGene Biosciences for ZNF589
Inhibitory RNA Products
- Origene RNAi, shRNA, and siRNA products in human, mouse, rat for ZNF589
- Browse OriGene Inhibitory RNA Products For ZNF589
-
ViGene Biosciences ready-to-package AAV shRNAs for ZNF589 gene
Clone Products
- OriGene clones in human for ZNF589
- OriGene ORF clones in human for ZNF589
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
Flow Cytometry Products
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6a | · | 6b | · | 6c | · | 6d | ^ | 7 | ^ | 8 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | |||||||||||||||||||||||||
| SP2: | - | - | - | - | - | - | - | ||||||||||||||||||
| SP3: | - | - | |||||||||||||||||||||||
| SP4: | - | - | |||||||||||||||||||||||
| SP5: | - | - | - | - | - | - | |||||||||||||||||||
| SP6: |
Expression for ZNF589 Gene
This gene is overexpressed in Fetal gut (32.5) and Testis (26.0).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for ZNF589 Gene
SOURCE GeneReport for Unigene cluster for ZNF589 Gene Hs.172602
mRNA Expression by UniProt/SwissProt for ZNF589 Gene
Q86UQ0-ZN589_HUMAN
Tissue specificity:
Isoform 2 is widely expressed. Isoform 3 is only expressed in CD34(+) cells.
Primer Products
-
OriGene qPCR primer pairs and template standards for ZNF589
-
OriGene qPCR primer pairs for ZNF589
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA differential expression in normal tissues for ZNF589 Gene
Orthologs for ZNF589 Gene
This gene was present in the common ancestor of human and chimp.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | ZNF589 35 |
|
||
| ZNF589 36 |
|
OneToOne |
- Species with no ortholog for ZNF589:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- cow (Bos Taurus)
- dog (Canis familiaris)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- lizard (Anolis carolinensis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- mouse (Mus musculus)
- oppossum (Monodelphis domestica)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- platypus (Ornithorhynchus anatinus)
- rainbow trout (Oncorhynchus mykiss)
- rat (Rattus norvegicus)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- tropical clawed frog (Silurana tropicalis)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
- zebrafish (Danio rerio)
Paralogs for ZNF589 Gene
(564) SIMAP similar genes for ZNF589 Gene using alignment to 6 proteins:
- ZNF790
- ZNF225
- ZNF224
- ZNF24
- ZNF415
- ZNF721
- ZNF738
- ZNF233
- PRMD9
- ZNF71
- ZNF544
- ZNF573
- ZNF257
- ZNF234
- ZNF789
- ZNF83
- ZNF78L1
- ZNF497
- ZNF391
- ZNF154
- ZNF141
- ZNF559
- ZNF155
- ZNF285
- PRDM9
- ZNF519
- ZNF320
- ZSCAN2
- ZNF792
- ZNF696
- ZFP3
- KRBOX4
- MGC12518
- ZNF528
- ZNF283
- ZSCAN30
- ZNF709
- ZNF510
- ZNF471
- ZNF436
- ZNF433
- ZNF394
- ZNF324
- ZNF28
- ZNF256
- ZNF239
- ZNF180
- ZNF157
- ZNF112
- FIK
- DKFZp686B16128
- ZNF223
- ZNF267
- ZNF230
- ZNF274
- ZNF177
- ZNF780B
- ZNF443
- ZNF264
- POM121C
- ZNF595
- ZNF682
- ZNF43
- ZNF226
- ZNF525
- ZNF675
- ZNF91
- ZNF70
- ZNF697
- ZNF658B
- ZNF658
- ZNF587
- ZNF582
- ZNF502
- ZNF41
- ZNF285A
- ZNF260
- MZF1
- DKFZp434G1621
- DKFZp313M0722
- LOC101928664
- ZNF677
- ZNF669
- ZNF596
- ZNF
- ZNF599
- ZSCAN31
- ZNF852
- HZF36
- ZNF208
- ZNF773
- ZNF527
- ZNF720
- ZSCAN9
- ZSCAN23
- ZSCAN21
- ZSCAN16
- ZSCAN12
- ZNF883
- ZNF853
- ZNF786
- ZNF761
- ZNF681
- ZNF665
- ZNF627
- ZNF493
- ZNF483
- ZNF45
- ZNF317
- ZNF286B
- ZNF266
- ZNF232
- ZNF213
- ZNF205
- ZKSCAN1
- ZFP41
- RhitH
- KIAA1829
- HZF11
- DKFZp761O1618
- DKFZp686H10254
- DKFZp666M039
- DKFZp666C237
- ZNF649
- ZFP90
- ZNF506
- ZNF583
- ZNF841
- ZNF514
- ZNF354B
- ZNF540
- ZNF667
- ZNF878
- ZNF846
- ZNF778
- ZNF146
- ZNF664
- ZNF500
- ZNF419
- ZNF84
- ZNF726
- ZNF195
- ZSCAN29
- ZSCAN10
- ZNF891
- ZNF85
- ZNF799
- ZNF718
- ZNF676
- ZNF670
- ZNF558
- ZNF37A
- ZNF358
- ZNF323
- ZFS-1
- ZFP14
- ZF6
- Nbla00121
- GLI4
- DKFZp686K03205
- DKFZp686D2168
- DKFZp434G1930
- ZNF420
- ZNF169
- ZNF432
- ZNF34
- ZNF350
- ZNF263
- ZNF221
- ZNF227
- ZNF430
- ZNF135
- ZNF577
- ZNF780A
- ZNF774
- ZNF695
- ZNF662
- ZNF585B
- ZNF345
- ZNF251
- ZNF615
- ZNF551
- ZNF607
- ZNF222
- ZNF845
- ZNF12
- ZFP30
- ZNF700
- ZNF426
- ZNF548
- zf30
- ZNF840
- ZNF823
- ZNF732
- ZNF672
- ZNF668
- ZNF605
- ZNF584
- ZNF492
- ZNF484
- ZNF468
- ZNF442
- ZNF425
- ZNF343
- ZNF136
- ZNF10
- ZKSCAN2
- DKFZp686G16228
- ZNF724P
- ZNF33A
- ZNF793
- ZNF616
- ZNF808
- ZNF791
- ZNF529
- ZNF300
- ZNF140
- ZNF93
- ZNF850
- ZNF35
- ZNF329
- ZNF304
- HKR1
- ZNF766
- ZNF90
- ZNF707
- ZNF569
- ZNF429
- ZNF550
- ZNF431
- ZNF701
- ZNF836
- ZNF782
- ZNF768
- ZNF729
- ZNF708
- ZNF691
- ZNF674
- ZNF566
- ZNF56
- ZNF556
- ZNF491
- ZNF480
- ZNF441
- ZNF396
- ZNF334
- ZNF287
- ZKSCAN8
- HZF40
- HZF30
- HZF14
- DKFZp686O111
- DKFZp686M04222
- DKFZp572F2170
- ZNF705A
- ZNF485
- ZNF273
- ZNF98
- ZNF23
- ZNF66
- ZNF844
- ZNF547
- ZNF101
- ZNF181
- ZNF888
- ZNF614
- ZNF613
- ZNF572
- ZNF354A
- ZNF229
- ZNF383
- ZNF324B
- ZNF714
- ZNF606
- ZNF33B
- ZNF763
- ZNF133
- ZNF567
- ZNF7
- ZNF248
- ZSCAN25
- ZNF835
- ZNF813
- ZNF73
- ZNF498
- ZNF473
- ZNF449
- ZNF382
- ZNF322
- ZNF254
- ZNF121
- ZFP37
- RBAK
- DKFZp686J1732
- ZNF816
- ZNF282
- ZNF571
- ZNF585A
- ZNF554
- ZNF32
- ZFP1
- ZNF501
- ZNF776
- ZNF20
- ZNF302
- ZNF546
- ZNF3
- ZNF728
- ZNF275
- ZNF737
- ZNF619
- ZNF235
- ZSCAN5B
- ZNF879
- ZNF814
- ZNF771
- ZNF713
- ZNF689
- ZNF586
- ZNF563
- ZNF470
- ZNF418
- ZNF204
- ZNF197
- ZNF174
- ZNF14
- ZNF117
- ZIM3
- ZFP62
- ZFP2
- ZBTB24
- E4F1
- DKFZp762K012
- ZNF565
- ZNF625
- ZNF561
- ZNF564
- ZNF16
- DKFZp547L155
- ZNF684
- ZNF570
- ZNF337
- ZNF189
- ZNF19
- ZIK1
- ZNF26
- ZNF100
- ZNF2
- ZNF331
- ZSCAN5C
- ZSCAN5A
- ZSCAN32
- ZNF812
- ZNF781
- ZNF75D
- ZNF75CP
- ZNF630
- ZNF560
- ZNF490
- ZNF439
- ZNF397
- ZNF268
- ZNF22
- ZNF200
- ZNF165
- ZKSCAN4
- HZF41
- DKFZp451F083
- ZNF461
- ZNF250
- ZNF124
- ZNF138
- ZNF416
- ZNF81
- ZNF880
- ZNF562
- ZNF8
- ZNF271
- ZNF182
- ZNF417
- ZNF805
- ZNF568
- ZNF460
- ZNF286A
- ZNF134
- ZSCAN26
- ZNF99
- ZNF92
- ZNF806
- ZNF79
- ZNF717
- ZNF716
- ZNF699
- ZNF671
- ZNF626
- ZNF623
- ZNF620
- ZNF610
- ZNF587B
- ZNF549
- ZNF355P
- ZNF25
- ZNF215
- ZNF114
- TIPUH1
- MST154
- FEZF2
- DKFZp686N14223
- DKFZp686H20223
- DKFZp571N1833
- DKFZp570I0164
- ZFP28
- ZNF479
- ZNF833P
- ZNF679
- ZNF17
- ZFP92
- ZNF160
- ZKSCAN7
- ZNF486
- ZSCAN4
- ZNF876P
- ZNF785
- ZNF749
- ZNF727
- ZNF628
- ZNF398
- ZNF319
- ZNF184
- ZNF175
- ZNF132
- HZF17
- HKR3
- GZF1
- ZNF440
- ZNF253
- ZNF578
- ZNF600
- ZNF543
- ZNF530
- ZNF214
- ZFP112
- ZNF678
- smap-7
- ZNF747
- ZNF726P1
- ZNF705G
- ZNF648
- ZNF487
- ZNF107
- ZKSCAN3
- ZBTB49
- ZBTB14
- OSR2
- FEZF1
- ZNF44
- ZNF629
- ZNF167
- ZBTB17
- ZNF333
- ZNF705F
- ZNF705E
- ZNF705D
- ZNF705B
- ZNF611
- ZNF557
- ZNF552
- ZNF445
- ZNF408
- ZNF354C
- ZNF347
- ZNF316
- ZNF311
- ZNF30
- ZNF18
- MYNN
- GD
- ZNF624
- ZNF74
- ZNF594
- ZNF772
- ZNF730
- ZNF69
- ZNF454
- ZNF77
- ZNF517
- ZNF211
- ZNF72
- ZSCAN22
- ZNF735
- ZNF702P
- ZNF641
- ZNF621
- ZNF444
- ZNF362
- ZNF202
- ZNF148
- ZFP82
- ZFP69
- WT1
- SNAI2
- REPIN1
- HZF28
- GFI1
- ZNF829
- ZNF765
- ZNF736
- ZNF534
- PRDM5
- DKFZp686C13142
- ZNF76
- ZNF860
- ZNF643
- ZNF574
- ZNF384
- ZNF143
- ZFP95
- ZFP69B
- ZBTB41
- SCRT2
- FP972
- DKFZp564M2178
- ZNF788
- ZNF660
- ZNF555
- ZKSCAN5
- DKFZp686L0787
- ZNF837
- ZNF777
- ZNF764
- ZNF680
- ZNF513
- ZNF410
- ZNF404
- ZBTB48
- PRDM6
- GFI1B
- AVGR8
- ZNF80
- ZNF652
- ZSCAN5D
- ZNF710
- ZNF57
- ZNF298
- ZBTB47
- SCRT1
- PRDM15
- PRDM1
- MECOM
- EVI1
- DKFZp666P0310
- ZNF75A
- PRDM10
- ZBTB16
- BCL6
- ZSCAN20
- LOC126295
- ZNF784
- ZNF526
- ZNF467
- ZNF366
- ZNF281
- ZNF137P
- PRDM16
Pseudogenes.org Pseudogenes for ZNF589 Gene
Variants for ZNF589 Gene
| SNP ID | Clin | Chr 03 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs11718329 | - | 48,268,338(+) | AGTCA(C/G/T)GTTTG | reference, missense | |
| rs9847953 | - | 48,241,205(+) | GCTGG(A/G)CTGCG | reference, missense | |
| rs3937 | -- | 48,270,912(-) | attcc(A/G)gacac | utr-variant-3-prime | |
| rs1045482 | -- | 48,270,739(+) | AGGAA(A/C/G/T)AAGGA | utr-variant-3-prime | |
| rs936427 | -- | 48,259,584(-) | CTCTT(C/T)TCTGA | intron-variant |
Residual Variation Intolerance Score:
81.7% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
5.79;
73.64% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for ZNF589 Gene
- Human Gene Mutation Database (HGMD)
- ZNF589
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF589 Gene
Disorders for ZNF589 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| kleefstra syndrome |
|
|
Search ZNF589 in MalaCards
View complete list of genes associated with diseases
Relevant External Links for ZNF589
- Atlas of Genetics and Cytogenetics in Oncology and Haematology:
- ZNF589
No data available for UniProtKB/Swiss-Prot and Genatlas for ZNF589 Gene
Publications for ZNF589 Gene
- SZF1: a novel KRAB-zinc finger gene expressed in CD34+ stem/progenitor cells. (PMID: 10029171) Liu C. … Small D. (Exp. Hematol. 1999) 2 3 4 23 67
- The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3
- Novel activity of KRAB domain that functions to reinforce nuclear localization of KRAB-containing zinc finger proteins by interacting with KAP1. (PMID: 23665872) Wang W. … Huang Z. (Cell. Mol. Life Sci. 2013) 3
- Toward a confocal subcellular atlas of the human proteome. (PMID: 18029348) Barbe L. … Andersson-Svahn H. (Mol. Cell Proteomics 2008) 3
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
Products for ZNF589 Gene
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Sources for ZNF589 Gene
- (1) GeneCards
- (2) HGNC
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