Free for academic non-profit institutions. Other users need a Commercial license

Aliases for ZNF587 Gene

Aliases for ZNF587 Gene

  • Zinc Finger Protein 587 2 3
  • Zinc Finger Protein Zfp6 3
  • ZF6 3

External Ids for ZNF587 Gene

Previous GeneCards Identifiers for ZNF587 Gene

  • GC19P063054
  • GC19P063055
  • GC19P058361
  • GC19P054672
  • GC19P058333

Summaries for ZNF587 Gene

GeneCards Summary for ZNF587 Gene

ZNF587 (Zinc Finger Protein 587) is a Protein Coding gene. Among its related pathways are Gene Expression and Gene Expression. An important paralog of this gene is ZNF17.

UniProtKB/Swiss-Prot for ZNF587 Gene

  • May be involved in transcriptional regulation

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF587 Gene

Genomics for ZNF587 Gene

Regulatory Elements for ZNF587 Gene

Transcription factor binding sites by QIAGEN in the ZNF587 gene promoter:

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for ZNF587 Gene

Start:
57,849,813 bp from pter
End:
57,865,123 bp from pter
Size:
15,311 bases
Orientation:
Plus strand

Genomic View for ZNF587 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZNF587 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF587 Gene

Proteins for ZNF587 Gene

  • Protein details for ZNF587 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q96SQ5-ZN587_HUMAN
    Recommended name:
    Zinc finger protein 587
    Protein Accession:
    Q96SQ5
    Secondary Accessions:
    • A0AV72
    • G3V0H5
    • Q6ZMK8

    Protein attributes for ZNF587 Gene

    Size:
    575 amino acids
    Molecular mass:
    65622 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ZNF587 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZNF587 Gene

Proteomics data for ZNF587 Gene at MOPED

Post-translational modifications for ZNF587 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF587 Gene

ENSEMBL proteins:
Reactome Protein details:
REFSEQ proteins:

No data available for DME Specific Peptides for ZNF587 Gene

Domains for ZNF587 Gene

Gene Families for ZNF587 Gene

HGNC:
  • ZNF :Zinc fingers, C2H2-type

Suggested Antigen Peptide Sequences for ZNF587 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q96SQ5

UniProtKB/Swiss-Prot:

ZN587_HUMAN :
  • Q96SQ5
Domain:
  • Contains 1 KRAB domain.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 13 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF587: view

Function for ZNF587 Gene

Molecular function for ZNF587 Gene

UniProtKB/Swiss-Prot Function: May be involved in transcriptional regulation

Gene Ontology (GO) - Molecular Function for ZNF587 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding --
GO:0003677 DNA binding IEA --
GO:0005515 protein binding IPI 25416956
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF587: view

Animal Model Products

CRISPR Products

miRNA for ZNF587 Gene

miRTarBase miRNAs that target ZNF587

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZNF587

In Situ Assay Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for ZNF587 Gene

Localization for ZNF587 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF587 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF587 Gene COMPARTMENTS Subcellular localization image for ZNF587 gene
Compartment Confidence
nucleus 4

Gene Ontology (GO) - Cellular Components for ZNF587 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF587: view

Pathways for ZNF587 Gene

SuperPathways for ZNF587 Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF587: view

Pathways by source for ZNF587 Gene

2 Reactome pathways for ZNF587 Gene

Gene Ontology (GO) - Biological Process for ZNF587 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF587: view

Transcripts for ZNF587 Gene

Unigene Clusters for ZNF587 Gene

Zinc finger protein 587:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZNF587

Primer Products

  • OriGene qSTAR qPCR primer pairs in human,mouse,rat for ZNF587
  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF587 Gene

No ASD Table

Relevant External Links for ZNF587 Gene

GeneLoc Exon Structure for
ZNF587
ECgene alternative splicing isoforms for
ZNF587

Expression for ZNF587 Gene

mRNA expression in normal human tissues for ZNF587 Gene

SOURCE GeneReport for Unigene cluster for ZNF587 Gene Hs.642598

genes like me logo Genes that share expressions with ZNF587: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein expression and mRNA Expression by UniProt/SwissProt for ZNF587 Gene

Orthologs for ZNF587 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF587 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia -- 36
  • 97 (a)
ManyToMany
-- 36
  • 96 (a)
ManyToMany
dog
(Canis familiaris)
Mammalia -- 36
  • 52 (a)
OneToMany
Species with no ortholog for ZNF587:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF587 Gene

ENSEMBL:
Gene Tree for ZNF587 (if available)
TreeFam:
Gene Tree for ZNF587 (if available)

Paralogs for ZNF587 Gene

Selected SIMAP similar genes for ZNF587 Gene using alignment to 2 proteins:

Pseudogenes.org Pseudogenes for ZNF587 Gene

genes like me logo Genes that share paralogs with ZNF587: view

Variants for ZNF587 Gene

Sequence variations from dbSNP and Humsavar for ZNF587 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type MAF
rs1061990 -- 57,864,896(-) AGGCT(A/G)GAGTG utr-variant-3-prime
rs1061996 -- 57,865,116(-) AATCT(G/T)TTGTA utr-variant-3-prime
rs1061997 -- 57,864,869(-) GCTGA(C/T)TGCAA utr-variant-3-prime
rs1139067 -- 57,864,892(-) tagag(C/T)gcgat utr-variant-3-prime
rs3202855 -- 57,863,859(+) ACAAT(A/G)TTGTG utr-variant-3-prime

Structural Variations from Database of Genomic Variants (DGV) for ZNF587 Gene

Variant ID Type Subtype PubMed ID
nsv912528 CNV Gain 21882294
nsv912529 CNV Loss 21882294
dgv4029n71 CNV Gain 21882294
nsv7311 OTHER Inversion 18451855
esv2656978 CNV Deletion 23128226

Relevant External Links for ZNF587 Gene

HapMap Linkage Disequilibrium report
ZNF587

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF587 Gene

Disorders for ZNF587 Gene

No disorders were found for ZNF587 Gene.

No data available for UniProtKB/Swiss-Prot for ZNF587 Gene

Publications for ZNF587 Gene

  1. Computer sequence analysis of human highly conserved zinc finger modules. (PMID: 10520746) Petroni D. … Comi P. (DNA Seq. 1998) 2 3
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  4. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  5. Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening. (PMID: 17474147) Wu C. … Li S.S. (Proteomics 2007) 3

Products for ZNF587 Gene

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat
  • QIAGEN qRT-PCR Assays for microRNAs that regulate ZNF587
    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat
    • Predesigned siRNA for gene silencing in human,mouse,rat for ZNF587
    • Block miRNA regulation of ZNF587 using miScript Target Protectors

    Sources for ZNF587 Gene

    Back to Top

    Content