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Aliases for ZNF585B Gene

Aliases for ZNF585B Gene

  • Zinc Finger Protein 585B 2 3
  • Zinc Finger Protein 41-Like Protein 3 4
  • SZFP41 3

External Ids for ZNF585B Gene

Previous GeneCards Identifiers for ZNF585B Gene

  • GC19M042335
  • GC19M042367
  • GC19M037675
  • GC19M034141
  • GC19M037677

Summaries for ZNF585B Gene

GeneCards Summary for ZNF585B Gene

ZNF585B (Zinc Finger Protein 585B) is a Protein Coding gene. Among its related pathways are Gene Expression and Gene Expression. GO annotations related to this gene include nucleic acid binding. An important paralog of this gene is ZNF268.

UniProtKB/Swiss-Prot for ZNF585B Gene

  • May be involved in transcriptional regulation

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF585B Gene

Genomics for ZNF585B Gene

Regulatory Elements for ZNF585B Gene

Genomic Location for ZNF585B Gene

Start:
37,181,579 bp from pter
End:
37,218,153 bp from pter
Size:
36,575 bases
Orientation:
Minus strand

Genomic View for ZNF585B Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZNF585B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF585B Gene

Proteins for ZNF585B Gene

  • Protein details for ZNF585B Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q52M93-Z585B_HUMAN
    Recommended name:
    Zinc finger protein 585B
    Protein Accession:
    Q52M93
    Secondary Accessions:
    • Q8IZD3
    • Q96JW6

    Protein attributes for ZNF585B Gene

    Size:
    769 amino acids
    Molecular mass:
    88066 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAB55400.1; Type=Erroneous initiation; Evidence={ECO:0000305};

neXtProt entry for ZNF585B Gene

Proteomics data for ZNF585B Gene at MOPED

Post-translational modifications for ZNF585B Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF585B Gene

No data available for DME Specific Peptides for ZNF585B Gene

Domains for ZNF585B Gene

Gene Families for ZNF585B Gene

HGNC:
  • ZNF :Zinc fingers, C2H2-type

Protein Domains for ZNF585B Gene

Suggested Antigen Peptide Sequences for ZNF585B Gene

Graphical View of Domain Structure for InterPro Entry

Q52M93

UniProtKB/Swiss-Prot:

Z585B_HUMAN :
  • Q52M93
Domain:
  • Contains 1 KRAB domain.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 21 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF585B: view

Function for ZNF585B Gene

Molecular function for ZNF585B Gene

UniProtKB/Swiss-Prot Function: May be involved in transcriptional regulation

Gene Ontology (GO) - Molecular Function for ZNF585B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding IEA --
GO:0003700 sequence-specific DNA binding transcription factor activity IBA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF585B: view

Animal Model Products

CRISPR Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for ZNF585B Gene

Localization for ZNF585B Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF585B Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF585B Gene COMPARTMENTS Subcellular localization image for ZNF585B gene
Compartment Confidence
nucleus 3

Gene Ontology (GO) - Cellular Components for ZNF585B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF585B: view

Pathways for ZNF585B Gene

SuperPathways for ZNF585B Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF585B: view

Pathways by source for ZNF585B Gene

2 Reactome pathways for ZNF585B Gene

Interacting Proteins for ZNF585B Gene

Gene Ontology (GO) - Biological Process for ZNF585B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IBA --
genes like me logo Genes that share ontologies with ZNF585B: view

Transcripts for ZNF585B Gene

Unigene Clusters for ZNF585B Gene

Zinc finger protein 585B:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZNF585B

Primer Products

  • OriGene qSTAR qPCR primer pairs in human,mouse,rat for ZNF585B
  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF585B Gene

No ASD Table

Relevant External Links for ZNF585B Gene

GeneLoc Exon Structure for
ZNF585B
ECgene alternative splicing isoforms for
ZNF585B

Expression for ZNF585B Gene

mRNA expression in normal human tissues for ZNF585B Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for ZNF585B Gene

SOURCE GeneReport for Unigene cluster for ZNF585B Gene Hs.390568

genes like me logo Genes that share expressions with ZNF585B: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ZNF585B Gene

Orthologs for ZNF585B Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZNF585B Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF585B 35
  • 98.4 (n)
  • 98.18 (a)
ZNF585B 36
  • 98 (a)
OneToOne
cow
(Bos Taurus)
Mammalia -- 36
  • 35 (a)
ManyToMany
mouse
(Mus musculus)
Mammalia Zfp27 36
  • 70 (a)
OneToMany
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 40 (a)
ManyToMany
-- 36
  • 45 (a)
ManyToMany
-- 36
  • 42 (a)
ManyToMany
-- 36
  • 44 (a)
ManyToMany
-- 36
  • 43 (a)
ManyToMany
-- 36
  • 47 (a)
ManyToMany
-- 36
  • 41 (a)
ManyToMany
-- 36
  • 44 (a)
ManyToMany
-- 36
  • 39 (a)
ManyToMany
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 35 (a)
ManyToMany
-- 36
  • 33 (a)
ManyToMany
-- 36
  • 43 (a)
ManyToMany
-- 36
  • 36 (a)
ManyToMany
-- 36
  • 39 (a)
ManyToMany
CSA.1668 36
  • 31 (a)
ManyToMany
Species with no ortholog for ZNF585B:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF585B Gene

ENSEMBL:
Gene Tree for ZNF585B (if available)
TreeFam:
Gene Tree for ZNF585B (if available)

Paralogs for ZNF585B Gene

Selected SIMAP similar genes for ZNF585B Gene using alignment to 9 proteins:

Pseudogenes.org Pseudogenes for ZNF585B Gene

genes like me logo Genes that share paralogs with ZNF585B: view

Variants for ZNF585B Gene

Sequence variations from dbSNP and Humsavar for ZNF585B Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type MAF
rs167673 -- 37,212,533(+) Ttttt(G/T)attgc upstream-variant-2KB
rs170379 -- 37,203,893(+) aaagt(G/T)ctggg intron-variant
rs178615 -- 37,195,310(+) cactg(C/G)actcc intron-variant
rs184408 -- 37,212,162(+) ctgca(A/G)ccttg upstream-variant-2KB
rs188877 -- 37,209,394(+) CACCA(G/T)GCCCG intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF585B Gene

Variant ID Type Subtype PubMed ID
dgv3856n71 CNV Gain 21882294
nsv911655 CNV Loss 21882294

Relevant External Links for ZNF585B Gene

HapMap Linkage Disequilibrium report
ZNF585B

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF585B Gene

Disorders for ZNF585B Gene

Relevant External Links for ZNF585B

Genetic Association Database (GAD)
ZNF585B
genes like me logo Genes that share disorders with ZNF585B: view

No data available for UniProtKB/Swiss-Prot for ZNF585B Gene

Publications for ZNF585B Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  4. A human protein-protein interaction network: a resource for annotating the proteome. (PMID: 16169070) Stelzl U. … Wanker E.E. (Cell 2005) 3
  5. Human POGZ modulates dissociation of HP1alpha from mitotic chromosome arms through Aurora B activation. (PMID: 20562864) Nozawa R.S. … Obuse C. (Nat. Cell Biol. 2010) 3

Products for ZNF585B Gene

Sources for ZNF585B Gene

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