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Aliases for ZNF585A Gene

Aliases for ZNF585A Gene

  • Zinc Finger Protein 585A 2 3

External Ids for ZNF585A Gene

Previous GeneCards Identifiers for ZNF585A Gene

  • GC19M042334
  • GC19M042337
  • GC19M042289
  • GC19M037597
  • GC19M034110

Summaries for ZNF585A Gene

GeneCards Summary for ZNF585A Gene

ZNF585A (Zinc Finger Protein 585A) is a Protein Coding gene. Among its related pathways are Gene Expression and Gene Expression. GO annotations related to this gene include nucleic acid binding. An important paralog of this gene is ZNF268.

UniProtKB/Swiss-Prot for ZNF585A Gene

  • May be involved in transcriptional regulation

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF585A Gene

Genomics for ZNF585A Gene

Regulatory Elements for ZNF585A Gene

Transcription factor binding sites by QIAGEN in the ZNF585A gene promoter:

Genomic Location for ZNF585A Gene

Start:
37,106,734 bp from pter
End:
37,172,741 bp from pter
Size:
66,008 bases
Orientation:
Minus strand

Genomic View for ZNF585A Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZNF585A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF585A Gene

Proteins for ZNF585A Gene

  • Protein details for ZNF585A Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6P3V2-Z585A_HUMAN
    Recommended name:
    Zinc finger protein 585A
    Protein Accession:
    Q6P3V2
    Secondary Accessions:
    • Q8TE95
    • Q96MV3

    Protein attributes for ZNF585A Gene

    Size:
    769 amino acids
    Molecular mass:
    87974 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAB85057.1; Type=Erroneous initiation; Evidence={ECO:0000305};

    Alternative splice isoforms for ZNF585A Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZNF585A Gene

Proteomics data for ZNF585A Gene at MOPED

Post-translational modifications for ZNF585A Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF585A Gene

No data available for DME Specific Peptides for ZNF585A Gene

Domains for ZNF585A Gene

Gene Families for ZNF585A Gene

HGNC:
  • ZNF :Zinc fingers, C2H2-type

Protein Domains for ZNF585A Gene

Suggested Antigen Peptide Sequences for ZNF585A Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q6P3V2

UniProtKB/Swiss-Prot:

Z585A_HUMAN :
  • Q6P3V2
Domain:
  • Contains 1 KRAB domain.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 22 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF585A: view

Function for ZNF585A Gene

Molecular function for ZNF585A Gene

UniProtKB/Swiss-Prot Function: May be involved in transcriptional regulation

Gene Ontology (GO) - Molecular Function for ZNF585A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding IEA --
GO:0003700 sequence-specific DNA binding transcription factor activity IBA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF585A: view

Phenotypes for ZNF585A Gene

genes like me logo Genes that share phenotypes with ZNF585A: view

No data available for Enzyme Numbers (IUBMB) , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for ZNF585A Gene

Localization for ZNF585A Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF585A Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF585A Gene COMPARTMENTS Subcellular localization image for ZNF585A gene
Compartment Confidence
nucleus 3
cytosol 2

Gene Ontology (GO) - Cellular Components for ZNF585A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF585A: view

Pathways for ZNF585A Gene

SuperPathways for ZNF585A Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF585A: view

Pathways by source for ZNF585A Gene

2 Reactome pathways for ZNF585A Gene

Interacting Proteins for ZNF585A Gene

Gene Ontology (GO) - Biological Process for ZNF585A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IBA --
genes like me logo Genes that share ontologies with ZNF585A: view

Transcripts for ZNF585A Gene

Unigene Clusters for ZNF585A Gene

Zinc finger protein 585A:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF585A Gene

ExUns: 1a · 1b · 1c ^ 2a · 2b ^ 3 ^ 4a · 4b ^ 5 ^ 6 ^ 7 ^ 8a · 8b · 8c · 8d ^ 9
SP1: - - - -
SP2: - -
SP3: - - - - - - - - -
SP4: - - - - -
SP5: - - - - -
SP6: - - - -
SP7: - - - -
SP8: - -

Relevant External Links for ZNF585A Gene

GeneLoc Exon Structure for
ZNF585A
ECgene alternative splicing isoforms for
ZNF585A

Expression for ZNF585A Gene

mRNA expression in normal human tissues for ZNF585A Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for ZNF585A Gene

SOURCE GeneReport for Unigene cluster for ZNF585A Gene Hs.659236

genes like me logo Genes that share expressions with ZNF585A: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ZNF585A Gene

Orthologs for ZNF585A Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZNF585A Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF585A 35
  • 99.09 (n)
  • 98.83 (a)
ZNF585A 36
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia ZNF484 36
  • 46 (a)
OneToMany
ZNF585A 35
  • 89.03 (n)
  • 90.51 (a)
dog
(Canis familiaris)
Mammalia -- 36
  • 45 (a)
OneToMany
ZNF585A 35
  • 77.06 (n)
  • 74.97 (a)
mouse
(Mus musculus)
Mammalia Zfp27 35
  • 81.1 (n)
  • 82.44 (a)
Zfp27 16
Zfp27 36
  • 69 (a)
OneToMany
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 38 (a)
ManyToMany
-- 36
  • 42 (a)
ManyToMany
-- 36
  • 40 (a)
ManyToMany
-- 36
  • 45 (a)
ManyToMany
-- 36
  • 41 (a)
ManyToMany
-- 36
  • 45 (a)
ManyToMany
-- 36
  • 38 (a)
ManyToMany
-- 36
  • 41 (a)
ManyToMany
-- 36
  • 36 (a)
ManyToMany
rat
(Rattus norvegicus)
Mammalia LOC102550277 35
  • 79.52 (n)
  • 80.87 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC101733764 35
  • 55.78 (n)
  • 50.69 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 35 (a)
ManyToMany
-- 36
  • 33 (a)
ManyToMany
-- 36
  • 43 (a)
ManyToMany
-- 36
  • 37 (a)
ManyToMany
-- 36
  • 39 (a)
ManyToMany
CSA.1668 36
  • 32 (a)
ManyToMany
Species with no ortholog for ZNF585A:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF585A Gene

ENSEMBL:
Gene Tree for ZNF585A (if available)
TreeFam:
Gene Tree for ZNF585A (if available)

Paralogs for ZNF585A Gene

Selected SIMAP similar genes for ZNF585A Gene using alignment to 5 proteins:

genes like me logo Genes that share paralogs with ZNF585A: view

Variants for ZNF585A Gene

Sequence variations from dbSNP and Humsavar for ZNF585A Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type MAF
rs1047324 -- 37,151,610(+) TGATG(A/G)ACGCT reference, synonymous-codon
rs1047333 -- 37,151,263(-) GTTAA(C/T)GATAA utr-variant-3-prime
rs1129452 -- 37,151,214(-) GAATG(A/G)TAAGA utr-variant-3-prime
rs1129453 -- 37,151,210(-) GGTAA(A/G)ACAAC utr-variant-3-prime
rs1129978 -- 37,170,023(-) TGGGC(A/C)AGATT utr-variant-5-prime, nc-transcript-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF585A Gene

Variant ID Type Subtype PubMed ID
dgv3856n71 CNV Gain 21882294
nsv2477 CNV Loss 18451855
nsv828545 CNV Loss 20364138
nsv911655 CNV Loss 21882294

Relevant External Links for ZNF585A Gene

HapMap Linkage Disequilibrium report
ZNF585A

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF585A Gene

Disorders for ZNF585A Gene

No disorders were found for ZNF585A Gene.

No data available for UniProtKB/Swiss-Prot for ZNF585A Gene

Publications for ZNF585A Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  4. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  5. Human POGZ modulates dissociation of HP1alpha from mitotic chromosome arms through Aurora B activation. (PMID: 20562864) Nozawa R.S. … Obuse C. (Nat. Cell Biol. 2010) 3

Products for ZNF585A Gene

Sources for ZNF585A Gene

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