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Aliases for ZNF585A Gene

Aliases for ZNF585A Gene

  • Zinc Finger Protein 585A 2 3 5

External Ids for ZNF585A Gene

Previous GeneCards Identifiers for ZNF585A Gene

  • GC19M042334
  • GC19M042337
  • GC19M042289
  • GC19M037597
  • GC19M034110
  • GC19M037109
  • GC19M037114

Summaries for ZNF585A Gene

GeneCards Summary for ZNF585A Gene

ZNF585A (Zinc Finger Protein 585A) is a Protein Coding gene. Among its related pathways are Gene Expression. GO annotations related to this gene include nucleic acid binding and transcription factor activity, sequence-specific DNA binding. An important paralog of this gene is ZNF607.

UniProtKB/Swiss-Prot for ZNF585A Gene

  • May be involved in transcriptional regulation.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF585A Gene

Genomics for ZNF585A Gene

Regulatory Elements for ZNF585A Gene

Enhancers for ZNF585A Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around ZNF585A on UCSC Golden Path with GeneCards custom track

Promoters for ZNF585A Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around ZNF585A on UCSC Golden Path with GeneCards custom track

Transcription factor binding sites by QIAGEN in the ZNF585A gene promoter:

Genomic Location for ZNF585A Gene

Chromosome:
19
Start:
37,106,734 bp from pter
End:
37,172,741 bp from pter
Size:
66,008 bases
Orientation:
Minus strand

Genomic View for ZNF585A Gene

Genes around ZNF585A on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF585A Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF585A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF585A Gene

Proteins for ZNF585A Gene

  • Protein details for ZNF585A Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6P3V2-Z585A_HUMAN
    Recommended name:
    Zinc finger protein 585A
    Protein Accession:
    Q6P3V2
    Secondary Accessions:
    • Q8TE95
    • Q96MV3

    Protein attributes for ZNF585A Gene

    Size:
    769 amino acids
    Molecular mass:
    87974 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAB85057.1; Type=Erroneous initiation; Evidence={ECO:0000305};

    Alternative splice isoforms for ZNF585A Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZNF585A Gene

Proteomics data for ZNF585A Gene at MOPED

Post-translational modifications for ZNF585A Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF585A Gene

No data available for DME Specific Peptides for ZNF585A Gene

Domains & Families for ZNF585A Gene

Gene Families for ZNF585A Gene

Protein Domains for ZNF585A Gene

Suggested Antigen Peptide Sequences for ZNF585A Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q6P3V2

UniProtKB/Swiss-Prot:

Z585A_HUMAN :
  • Contains 1 KRAB domain.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 22 C2H2-type zinc fingers.
Domain:
  • Contains 1 KRAB domain.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 22 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF585A: view

Function for ZNF585A Gene

Molecular function for ZNF585A Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Gene Ontology (GO) - Molecular Function for ZNF585A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding IEA --
genes like me logo Genes that share ontologies with ZNF585A: view
genes like me logo Genes that share phenotypes with ZNF585A: view

Animal Model Products

CRISPR Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF585A Gene

Localization for ZNF585A Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF585A Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF585A Gene COMPARTMENTS Subcellular localization image for ZNF585A gene
Compartment Confidence
nucleus 5
cytosol 2

No data available for Gene Ontology (GO) - Cellular Components for ZNF585A Gene

Pathways & Interactions for ZNF585A Gene

SuperPathways for ZNF585A Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF585A: view

Pathways by source for ZNF585A Gene

2 Reactome pathways for ZNF585A Gene

Interacting Proteins for ZNF585A Gene

Gene Ontology (GO) - Biological Process for ZNF585A Gene

None

No data available for SIGNOR curated interactions for ZNF585A Gene

Drugs & Compounds for ZNF585A Gene

No Compound Related Data Available

Transcripts for ZNF585A Gene

Unigene Clusters for ZNF585A Gene

Zinc finger protein 585A:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF585A Gene

ExUns: 1a · 1b · 1c ^ 2a · 2b ^ 3 ^ 4a · 4b ^ 5 ^ 6 ^ 7 ^ 8a · 8b · 8c · 8d ^ 9
SP1: - - - -
SP2: - -
SP3: - - - - - - - - -
SP4: - - - - -
SP5: - - - - -
SP6: - - - -
SP7: - - - -
SP8: - -

Relevant External Links for ZNF585A Gene

GeneLoc Exon Structure for
ZNF585A
ECgene alternative splicing isoforms for
ZNF585A

Expression for ZNF585A Gene

mRNA expression in normal human tissues for ZNF585A Gene

Protein differential expression in normal tissues from HIPED for ZNF585A Gene

This gene is overexpressed in Liver, secretome (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for ZNF585A Gene



SOURCE GeneReport for Unigene cluster for ZNF585A Gene Hs.659236

genes like me logo Genes that share expression patterns with ZNF585A: view

Protein tissue co-expression partners for ZNF585A Gene

- Elite partner

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ZNF585A Gene

Orthologs for ZNF585A Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZNF585A Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia ZNF585A 35
  • 89.03 (n)
  • 90.51 (a)
ZNF484 36
  • 46 (a)
OneToMany
dog
(Canis familiaris)
Mammalia ZNF585A 35
  • 77.06 (n)
  • 74.97 (a)
-- 36
  • 45 (a)
OneToMany
mouse
(Mus musculus)
Mammalia Zfp27 35
  • 81.1 (n)
  • 82.44 (a)
Zfp27 16
Zfp27 36
  • 69 (a)
OneToMany
chimpanzee
(Pan troglodytes)
Mammalia ZNF585A 35
  • 99.09 (n)
  • 98.83 (a)
ZNF585A 36
  • 99 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia LOC102550277 35
  • 79.52 (n)
  • 80.87 (a)
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 38 (a)
ManyToMany
-- 36
  • 42 (a)
ManyToMany
-- 36
  • 40 (a)
ManyToMany
-- 36
  • 45 (a)
ManyToMany
-- 36
  • 41 (a)
ManyToMany
-- 36
  • 45 (a)
ManyToMany
-- 36
  • 38 (a)
ManyToMany
-- 36
  • 41 (a)
ManyToMany
-- 36
  • 36 (a)
ManyToMany
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC101733764 35
  • 55.78 (n)
  • 50.69 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 35 (a)
ManyToMany
-- 36
  • 33 (a)
ManyToMany
-- 36
  • 43 (a)
ManyToMany
-- 36
  • 37 (a)
ManyToMany
-- 36
  • 39 (a)
ManyToMany
CSA.1668 36
  • 32 (a)
ManyToMany
Species with no ortholog for ZNF585A:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF585A Gene

ENSEMBL:
Gene Tree for ZNF585A (if available)
TreeFam:
Gene Tree for ZNF585A (if available)

Paralogs for ZNF585A Gene

(538) SIMAP similar genes for ZNF585A Gene using alignment to 5 proteins:

genes like me logo Genes that share paralogs with ZNF585A: view

Variants for ZNF585A Gene

Sequence variations from dbSNP and Humsavar for ZNF585A Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
rs7258160 -- 37,155,063(+) tggcg(C/T)gatct intron-variant
rs7258808 -- 37,173,136(+) GCCAG(A/G)GAAAA upstream-variant-2KB
rs7260386 -- 37,158,656(+) gactt(A/T)agagc intron-variant
rs8100552 -- 37,168,463(+) tctgt(A/C)attat intron-variant
rs8100725 -- 37,146,965(+) CTGTG(C/T)GGGGC downstream-variant-500B

Structural Variations from Database of Genomic Variants (DGV) for ZNF585A Gene

Variant ID Type Subtype PubMed ID
dgv3856n71 CNV Gain 21882294
nsv2477 CNV Loss 18451855
nsv828545 CNV Loss 20364138
nsv911655 CNV Loss 21882294

Variation tolerance for ZNF585A Gene

Residual Variation Intolerance Score: 51.6% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 4.86; 67.35% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for ZNF585A Gene

Disorders for ZNF585A Gene

Relevant External Links for ZNF585A

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ZNF585A

No disorders were found for ZNF585A Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF585A Gene

Publications for ZNF585A Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 67
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  3. Human POGZ modulates dissociation of HP1alpha from mitotic chromosome arms through Aurora B activation. (PMID: 20562864) Nozawa R.S. … Obuse C. (Nat. Cell Biol. 2010) 3
  4. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3

Products for ZNF585A Gene

Sources for ZNF585A Gene

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