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Aliases for ZNF583 Gene

Aliases for ZNF583 Gene

  • Zinc Finger Protein 583 2 3
  • Zinc Finger Protein L3-5 4

External Ids for ZNF583 Gene

Previous GeneCards Identifiers for ZNF583 Gene

  • GC19P061611
  • GC19P061612
  • GC19P056930
  • GC19P053224
  • GC19P056932
  • GC19P056934
  • GC19P056936
  • GC19P056941
  • GC19P056946
  • GC19P056953
  • GC19P056962

Summaries for ZNF583 Gene

GeneCards Summary for ZNF583 Gene

ZNF583 (Zinc Finger Protein 583) is a Protein Coding gene. Among its related pathways are Gene Expression and Gene Expression. An important paralog of this gene is ZNF529.

UniProtKB/Swiss-Prot for ZNF583 Gene

  • May be involved in transcriptional regulation

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF583 Gene

Genomics for ZNF583 Gene

Regulatory Elements for ZNF583 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for ZNF583 Gene

56,397,966 bp from pter
56,436,035 bp from pter
38,070 bases
Plus strand

Genomic View for ZNF583 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZNF583 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF583 Gene

Proteins for ZNF583 Gene

  • Protein details for ZNF583 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Zinc finger protein 583
    Protein Accession:
    Secondary Accessions:
    • O14850
    • Q2NKK3

    Protein attributes for ZNF583 Gene

    569 amino acids
    Molecular mass:
    66033 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZNF583 Gene

Proteomics data for ZNF583 Gene at MOPED

Post-translational modifications for ZNF583 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF583 Gene

ENSEMBL proteins:
Reactome Protein details:
REFSEQ proteins:

No data available for DME Specific Peptides for ZNF583 Gene

Domains for ZNF583 Gene

Gene Families for ZNF583 Gene

  • ZNF :Zinc fingers, C2H2-type

Protein Domains for ZNF583 Gene

Suggested Antigen Peptide Sequences for ZNF583 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Q96ND8
  • Contains 1 KRAB domain.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 12 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF583: view

Function for ZNF583 Gene

Molecular function for ZNF583 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation

Gene Ontology (GO) - Molecular Function for ZNF583 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding --
GO:0003677 DNA binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF583: view

Phenotypes for ZNF583 Gene

GenomeRNAi human phenotypes for ZNF583:
genes like me logo Genes that share phenotypes with ZNF583: view

Animal Model Products

CRISPR Products

No data available for Enzyme Numbers (IUBMB) , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for ZNF583 Gene

Localization for ZNF583 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF583 Gene

Subcellular locations from

Jensen Localization Image for ZNF583 Gene COMPARTMENTS Subcellular localization image for ZNF583 gene
Compartment Confidence
nucleus 3
cytosol 2

Gene Ontology (GO) - Cellular Components for ZNF583 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF583: view

Pathways for ZNF583 Gene

SuperPathways for ZNF583 Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF583: view

Pathways by source for ZNF583 Gene

2 Reactome pathways for ZNF583 Gene

Interacting Proteins for ZNF583 Gene

Gene Ontology (GO) - Biological Process for ZNF583 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF583: view

Transcripts for ZNF583 Gene

CRISPR Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZNF583

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF583 Gene

ExUns: 1 ^ 2a · 2b · 2c · 2d ^ 3 ^ 4a · 4b ^ 5a · 5b ^ 6a · 6b · 6c
SP1: - - - - - -
SP2: - -
SP3: - - -
SP4: -

Relevant External Links for ZNF583 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ZNF583 Gene

mRNA expression in normal human tissues for ZNF583 Gene

Protein differential expression in normal tissues for ZNF583 Gene

This gene is overexpressed in Retina (50.3) and Esophagus (18.2).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for ZNF583 Gene

SOURCE GeneReport for Unigene cluster for ZNF583 Gene Hs.146854

genes like me logo Genes that share expressions with ZNF583: view

Expression partners for ZNF583 Gene

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ZNF583 Gene

Orthologs for ZNF583 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF583 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia ZNF583 35
  • 89.34 (n)
  • 90.41 (a)
ZNF583 36
  • 90 (a)
(Mus musculus)
Mammalia Zfp583 35
  • 85.27 (n)
  • 82.75 (a)
Zfp583 16
Zfp583 36
  • 83 (a)
(Pan troglodytes)
Mammalia ZNF583 35
  • 99.59 (n)
  • 99.82 (a)
ZNF583 36
  • 100 (a)
(Rattus norvegicus)
Mammalia Zfp583 35
  • 83.8 (n)
  • 82.57 (a)
(Canis familiaris)
Mammalia ZNF583 36
  • 91 (a)
Species with no ortholog for ZNF583:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF583 Gene

Gene Tree for ZNF583 (if available)
Gene Tree for ZNF583 (if available)

Paralogs for ZNF583 Gene

Selected SIMAP similar genes for ZNF583 Gene using alignment to 3 proteins:

genes like me logo Genes that share paralogs with ZNF583: view

Variants for ZNF583 Gene

Sequence variations from dbSNP and Humsavar for ZNF583 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type MAF
rs917649 -- 56,413,392(+) TCAGT(A/G)TATAA intron-variant, upstream-variant-2KB
rs917650 -- 56,420,303(+) GGTTT(C/T)GGTAC intron-variant
rs917651 -- 56,422,495(+) GCCTA(C/G)TGTTG intron-variant
rs917652 -- 56,422,742(+) CTTAA(A/G)TTCTT intron-variant
rs1134488 -- 56,407,120(-) TCCTT(A/G)GACAT reference, synonymous-codon

Structural Variations from Database of Genomic Variants (DGV) for ZNF583 Gene

Variant ID Type Subtype PubMed ID
nsv912516 CNV Gain 21882294

Relevant External Links for ZNF583 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF583 Gene

Disorders for ZNF583 Gene

No disorders were found for ZNF583 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for ZNF583 Gene

Publications for ZNF583 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  3. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  4. Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions. (PMID: 15342556) Suzuki Y. … Sugano S. (Genome Res. 2004) 3
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for ZNF583 Gene

Sources for ZNF583 Gene

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