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Aliases for ZNF576 Gene

Aliases for ZNF576 Gene

  • Zinc Finger Protein 576 2 3

External Ids for ZNF576 Gene

Previous GeneCards Identifiers for ZNF576 Gene

  • GC19P048793
  • GC19P048794
  • GC19P044100
  • GC19P040531

Summaries for ZNF576 Gene

GeneCards Summary for ZNF576 Gene

ZNF576 (Zinc Finger Protein 576) is a Protein Coding gene. GO annotations related to this gene include sequence-specific DNA binding RNA polymerase II transcription factor activity.

UniProtKB/Swiss-Prot for ZNF576 Gene

  • May be involved in transcriptional regulation

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF576 Gene

Genomics for ZNF576 Gene

Regulatory Elements for ZNF576 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for ZNF576 Gene

Start:
43,596,392 bp from pter
End:
43,601,157 bp from pter
Size:
4,766 bases
Orientation:
Plus strand

Genomic View for ZNF576 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZNF576 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF576 Gene

Proteins for ZNF576 Gene

  • Protein details for ZNF576 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9H609-ZN576_HUMAN
    Recommended name:
    Zinc finger protein 576
    Protein Accession:
    Q9H609
    Secondary Accessions:
    • Q9BU03

    Protein attributes for ZNF576 Gene

    Size:
    170 amino acids
    Molecular mass:
    18890 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZNF576 Gene

Proteomics data for ZNF576 Gene at MOPED

Post-translational modifications for ZNF576 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF576 Gene

No data available for DME Specific Peptides for ZNF576 Gene

Domains for ZNF576 Gene

Gene Families for ZNF576 Gene

HGNC:
  • ZNF :Zinc fingers, C2H2-type

Protein Domains for ZNF576 Gene

Suggested Antigen Peptide Sequences for ZNF576 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q9H609

UniProtKB/Swiss-Prot:

ZN576_HUMAN :
  • Q9H609
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 4 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF576: view

Function for ZNF576 Gene

Molecular function for ZNF576 Gene

UniProtKB/Swiss-Prot Function: May be involved in transcriptional regulation

Gene Ontology (GO) - Molecular Function for ZNF576 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000981 sequence-specific DNA binding RNA polymerase II transcription factor activity IBA --
GO:0003677 DNA binding IEA --
GO:0005515 protein binding IPI 25416956
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF576: view
genes like me logo Genes that share phenotypes with ZNF576: view

Animal Model Products

CRISPR Products

No data available for Enzyme Numbers (IUBMB) , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for ZNF576 Gene

Localization for ZNF576 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF576 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF576 Gene COMPARTMENTS Subcellular localization image for ZNF576 gene
Compartment Confidence
nucleus 3
golgi apparatus 1

Gene Ontology (GO) - Cellular Components for ZNF576 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IBA --
genes like me logo Genes that share ontologies with ZNF576: view

Pathways for ZNF576 Gene

SuperPathways for ZNF576 Gene

No Data Available

Gene Ontology (GO) - Biological Process for ZNF576 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006357 regulation of transcription from RNA polymerase II promoter IBA --
GO:0006366 transcription from RNA polymerase II promoter IBA --
genes like me logo Genes that share ontologies with ZNF576: view

No data available for Pathways by source for ZNF576 Gene

Transcripts for ZNF576 Gene

mRNA/cDNA for ZNF576 Gene

Unigene Clusters for ZNF576 Gene

Zinc finger protein 576:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZNF576

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF576 Gene

ExUns: 1a · 1b · 1c · 1d · 1e · 1f · 1g ^ 2a · 2b ^ 3a · 3b · 3c · 3d
SP1: - - - - -
SP2: - - - - -
SP3: - -
SP4: -
SP5: -
SP6:

Relevant External Links for ZNF576 Gene

GeneLoc Exon Structure for
ZNF576
ECgene alternative splicing isoforms for
ZNF576

Expression for ZNF576 Gene

mRNA expression in normal human tissues for ZNF576 Gene

SOURCE GeneReport for Unigene cluster for ZNF576 Gene Hs.11110

genes like me logo Genes that share expressions with ZNF576: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein expression and mRNA Expression by UniProt/SwissProt for ZNF576 Gene

Orthologs for ZNF576 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZNF576 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF576 36
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia ZNF576 35
  • 88.43 (n)
  • 82.94 (a)
ZNF576 36
  • 83 (a)
OneToOne
dog
(Canis familiaris)
Mammalia ZNF576 35
  • 89.02 (n)
  • 84.71 (a)
zebrafish
(Danio rerio)
Actinopterygii ZNF576 (1 of 2) 36
  • 22 (a)
OneToMany
ZNF576 (2 of 2) 36
  • 2 (a)
OneToMany
Species with no ortholog for ZNF576:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ZNF576 Gene

ENSEMBL:
Gene Tree for ZNF576 (if available)
TreeFam:
Gene Tree for ZNF576 (if available)

Paralogs for ZNF576 Gene

No data available for Paralogs for ZNF576 Gene

Variants for ZNF576 Gene

Sequence variations from dbSNP and Humsavar for ZNF576 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type MAF
rs304723 -- 43,598,186(+) gacag(C/T)attca intron-variant
rs2240932 -- 43,598,858(+) CACCC(A/G)CTGCC missense, reference
rs2240933 -- 43,599,632(+) GCCCT(A/G)GACCT utr-variant-3-prime
rs8111680 -- 43,599,094(+) CTGAC(G/T)GTGGC missense, reference
rs10410931 -- 43,600,716(+) tgtgg(G/T)ggcat downstream-variant-500B

Structural Variations from Database of Genomic Variants (DGV) for ZNF576 Gene

Variant ID Type Subtype PubMed ID
nsv833839 CNV Loss 17160897

Relevant External Links for ZNF576 Gene

HapMap Linkage Disequilibrium report
ZNF576

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF576 Gene

Disorders for ZNF576 Gene

No disorders were found for ZNF576 Gene.

No data available for UniProtKB/Swiss-Prot for ZNF576 Gene

Publications for ZNF576 Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  4. Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions. (PMID: 15342556) Suzuki Y. … Sugano S. (Genome Res. 2004) 3
  5. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PMID: 17081983) Olsen J.V. … Mann M. (Cell 2006) 3

Products for ZNF576 Gene

Sources for ZNF576 Gene

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