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Aliases for ZNF575 Gene

Aliases for ZNF575 Gene

  • Zinc Finger Protein 575 2 3 5

External Ids for ZNF575 Gene

Previous GeneCards Identifiers for ZNF575 Gene

  • GC19P048730
  • GC19P048731
  • GC19P044030
  • GC19P040468

Summaries for ZNF575 Gene

GeneCards Summary for ZNF575 Gene

ZNF575 (Zinc Finger Protein 575) is a Protein Coding gene. GO annotations related to this gene include nucleic acid binding. An important paralog of this gene is ZNF497.

UniProtKB/Swiss-Prot for ZNF575 Gene

  • May be involved in transcriptional regulation.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF575 Gene

Genomics for ZNF575 Gene

Regulatory Elements for ZNF575 Gene

Enhancers for ZNF575 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around ZNF575 on UCSC Golden Path with GeneCards custom track

Promoters for ZNF575 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around ZNF575 on UCSC Golden Path with GeneCards custom track

Genomic Location for ZNF575 Gene

Chromosome:
19
Start:
43,525,497 bp from pter
End:
43,536,138 bp from pter
Size:
10,642 bases
Orientation:
Plus strand

Genomic View for ZNF575 Gene

Genes around ZNF575 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF575 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF575 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF575 Gene

Proteins for ZNF575 Gene

  • Protein details for ZNF575 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q86XF7-ZN575_HUMAN
    Recommended name:
    Zinc finger protein 575
    Protein Accession:
    Q86XF7
    Secondary Accessions:
    • B4DX54

    Protein attributes for ZNF575 Gene

    Size:
    245 amino acids
    Molecular mass:
    26763 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZNF575 Gene

Proteomics data for ZNF575 Gene at MOPED

Post-translational modifications for ZNF575 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF575 Gene

No data available for DME Specific Peptides for ZNF575 Gene

Domains & Families for ZNF575 Gene

Gene Families for ZNF575 Gene

Protein Domains for ZNF575 Gene

Suggested Antigen Peptide Sequences for ZNF575 Gene

Graphical View of Domain Structure for InterPro Entry

Q86XF7

UniProtKB/Swiss-Prot:

ZN575_HUMAN :
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 6 C2H2-type zinc fingers.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 6 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF575: view

Function for ZNF575 Gene

Molecular function for ZNF575 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.
genes like me logo Genes that share phenotypes with ZNF575: view

Animal Model Products

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for ZNF575 Gene

Localization for ZNF575 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF575 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF575 Gene COMPARTMENTS Subcellular localization image for ZNF575 gene
Compartment Confidence
nucleus 5
cytosol 2

No data available for Gene Ontology (GO) - Cellular Components for ZNF575 Gene

Pathways & Interactions for ZNF575 Gene

SuperPathways for ZNF575 Gene

No Data Available

Interacting Proteins for ZNF575 Gene

Gene Ontology (GO) - Biological Process for ZNF575 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF575: view

No data available for Pathways by source and SIGNOR curated interactions for ZNF575 Gene

Drugs & Compounds for ZNF575 Gene

No Compound Related Data Available

Transcripts for ZNF575 Gene

Unigene Clusters for ZNF575 Gene

Zinc finger protein 575:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF575 Gene

ExUns: 1a · 1b ^ 2 ^ 3a · 3b ^ 4a · 4b
SP1:
SP2: -

Relevant External Links for ZNF575 Gene

GeneLoc Exon Structure for
ZNF575
ECgene alternative splicing isoforms for
ZNF575

Expression for ZNF575 Gene

mRNA expression in normal human tissues for ZNF575 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for ZNF575 Gene



SOURCE GeneReport for Unigene cluster for ZNF575 Gene Hs.213534

genes like me logo Genes that share expression patterns with ZNF575: view

Primer Products

No data available for mRNA differential expression in normal tissues , Protein differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for ZNF575 Gene

Orthologs for ZNF575 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF575 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia ZNF575 35
  • 88.39 (n)
  • 90.98 (a)
ZNF575 36
  • 64 (a)
OneToOne
dog
(Canis familiaris)
Mammalia ZNF575 35
  • 88.16 (n)
  • 91.02 (a)
ZNF575 36
  • 64 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Zfp575 35
  • 84.66 (n)
  • 84.52 (a)
Zfp575 16
Zfp575 36
  • 83 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia ZNF575 35
  • 99.46 (n)
  • 98.78 (a)
ZNF575 36
  • 70 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Zfp575 35
  • 83.26 (n)
  • 82.43 (a)
Species with no ortholog for ZNF575:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF575 Gene

ENSEMBL:
Gene Tree for ZNF575 (if available)
TreeFam:
Gene Tree for ZNF575 (if available)

Paralogs for ZNF575 Gene

Paralogs for ZNF575 Gene

(201) SIMAP similar genes for ZNF575 Gene using alignment to 3 proteins:

genes like me logo Genes that share paralogs with ZNF575: view

Variants for ZNF575 Gene

Sequence variations from dbSNP and Humsavar for ZNF575 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
rs8100211 -- 43,531,006(+) GGGCG(C/T)GGTGG upstream-variant-2KB
rs12981701 -- 43,532,265(+) gtcag(C/G)tgatc intron-variant, upstream-variant-2KB
rs71169255 -- 43,530,311(+) TTTTT(-/T)GAGAT upstream-variant-2KB
rs71169258 -- 43,536,498(+) AAAAA(-/A)GCTGG downstream-variant-500B
rs8108980 -- 43,533,496(+) GCCCC(C/G)CCCCC intron-variant, utr-variant-5-prime

Structural Variations from Database of Genomic Variants (DGV) for ZNF575 Gene

Variant ID Type Subtype PubMed ID
nsv912107 CNV Loss 21882294

Variation tolerance for ZNF575 Gene

Residual Variation Intolerance Score: 76% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.60; 30.89% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for ZNF575 Gene

Disorders for ZNF575 Gene

Relevant External Links for ZNF575

Genetic Association Database (GAD)
ZNF575
Human Genome Epidemiology (HuGE) Navigator
ZNF575
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ZNF575

No disorders were found for ZNF575 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF575 Gene

Publications for ZNF575 Gene

  1. Association between genetic variants in VEGF, ERCC3 and occupational benzene haematotoxicity. (PMID: 19773279) Hosgood H.D. … Lan Q. (Occup Environ Med 2009) 3 48 67
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for ZNF575 Gene

Sources for ZNF575 Gene

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