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Aliases for ZNF574 Gene

Aliases for ZNF574 Gene

  • Zinc Finger Protein 574 2 3
  • FP972 3

External Ids for ZNF574 Gene

Previous GeneCards Identifiers for ZNF574 Gene

  • GC19P047273
  • GC19P047264
  • GC19P042572
  • GC19P039012

Summaries for ZNF574 Gene

GeneCards Summary for ZNF574 Gene

ZNF574 (Zinc Finger Protein 574) is a Protein Coding gene. An important paralog of this gene is ZNF526.

UniProtKB/Swiss-Prot for ZNF574 Gene

  • May be involved in transcriptional regulation

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF574 Gene

Genomics for ZNF574 Gene

Regulatory Elements for ZNF574 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for ZNF574 Gene

Start:
42,068,477 bp from pter
End:
42,081,567 bp from pter
Size:
13,091 bases
Orientation:
Plus strand

Genomic View for ZNF574 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZNF574 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF574 Gene

Proteins for ZNF574 Gene

  • Protein details for ZNF574 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6ZN55-ZN574_HUMAN
    Recommended name:
    Zinc finger protein 574
    Protein Accession:
    Q6ZN55
    Secondary Accessions:
    • Q6IPE0
    • Q6ZN10
    • Q7L5Z5
    • Q8NCE3
    • Q9H6N0

    Protein attributes for ZNF574 Gene

    Size:
    896 amino acids
    Molecular mass:
    98900 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ZNF574 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZNF574 Gene

Proteomics data for ZNF574 Gene at MOPED

Post-translational modifications for ZNF574 Gene

  • Ubiquitination at Lys405 and Lys558
  • Modification sites at PhosphoSitePlus

Other Protein References for ZNF574 Gene

No data available for DME Specific Peptides for ZNF574 Gene

Domains for ZNF574 Gene

Gene Families for ZNF574 Gene

HGNC:
  • ZNF :Zinc fingers, C2H2-type

Protein Domains for ZNF574 Gene

Suggested Antigen Peptide Sequences for ZNF574 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q6ZN55

UniProtKB/Swiss-Prot:

ZN574_HUMAN :
  • Q6ZN55
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 20 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF574: view

Function for ZNF574 Gene

Molecular function for ZNF574 Gene

UniProtKB/Swiss-Prot Function: May be involved in transcriptional regulation

Gene Ontology (GO) - Molecular Function for ZNF574 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF574: view

Phenotypes for ZNF574 Gene

GenomeRNAi human phenotypes for ZNF574:
genes like me logo Genes that share phenotypes with ZNF574: view

Animal Model Products

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZNF574

In Situ Assay Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for ZNF574 Gene

Localization for ZNF574 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF574 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF574 Gene COMPARTMENTS Subcellular localization image for ZNF574 gene
Compartment Confidence
nucleus 4

Gene Ontology (GO) - Cellular Components for ZNF574 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF574: view

Pathways for ZNF574 Gene

SuperPathways for ZNF574 Gene

No Data Available

Interacting Proteins for ZNF574 Gene

Gene Ontology (GO) - Biological Process for ZNF574 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF574: view

No data available for Pathways by source for ZNF574 Gene

Transcripts for ZNF574 Gene

Unigene Clusters for ZNF574 Gene

Zinc finger protein 574:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZNF574

Primer Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF574 Gene

ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6a · 6b · 6c · 6d
SP1: -
SP2:
SP3: - - - -
SP4: - - -

Relevant External Links for ZNF574 Gene

GeneLoc Exon Structure for
ZNF574
ECgene alternative splicing isoforms for
ZNF574

Expression for ZNF574 Gene

mRNA expression in normal human tissues for ZNF574 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for ZNF574 Gene

SOURCE GeneReport for Unigene cluster for ZNF574 Gene Hs.13323

genes like me logo Genes that share expressions with ZNF574: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ZNF574 Gene

Orthologs for ZNF574 Gene

This gene was present in the common ancestor of animals.

Orthologs for ZNF574 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF574 36
  • 97 (a)
OneToOne
cow
(Bos Taurus)
Mammalia ZNF574 35
  • 89.77 (n)
  • 95.54 (a)
ZNF574 36
  • 95 (a)
OneToOne
dog
(Canis familiaris)
Mammalia ZNF574 35
  • 88.04 (n)
  • 93.97 (a)
ZNF574 36
  • 87 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Zfp574 35
  • 87.6 (n)
  • 93.52 (a)
Zfp574 16
Zfp574 36
  • 94 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia ZNF574 36
  • 86 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Zfp574 35
  • 87.46 (n)
  • 93.84 (a)
lizard
(Anolis carolinensis)
Reptilia ZNF574 36
  • 57 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia znf574 35
  • 56.56 (n)
  • 53.46 (a)
zebrafish
(Danio rerio)
Actinopterygii znf574 36
  • 21 (a)
ManyToMany
worm
(Caenorhabditis elegans)
Secernentea Y48G8AL.10 36
  • 14 (a)
OneToMany
Species with no ortholog for ZNF574:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for ZNF574 Gene

ENSEMBL:
Gene Tree for ZNF574 (if available)
TreeFam:
Gene Tree for ZNF574 (if available)

Paralogs for ZNF574 Gene

Paralogs for ZNF574 Gene

genes like me logo Genes that share paralogs with ZNF574: view

Variants for ZNF574 Gene

Sequence variations from dbSNP and Humsavar for ZNF574 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type MAF
rs3745226 - 42,079,601(+) TCACC(A/G)GGAGG missense, reference
rs3745227 -- 42,079,862(+) TGTCC(C/T)TCTGC reference, missense
rs3745228 - 42,080,960(+) CCACC(A/G)GCGCC missense, reference
rs10413896 -- 42,081,681(+) GAGAA(G/T)GACCT downstream-variant-500B
rs10414151 -- 42,081,822(+) AACTT(G/T)CAGAG downstream-variant-500B

Structural Variations from Database of Genomic Variants (DGV) for ZNF574 Gene

Variant ID Type Subtype PubMed ID
nsv522854 CNV Gain 19592680
nsv520239 CNV Loss 19592680
nsv911782 CNV Loss 21882294
nsv911783 CNV Loss 21882294
esv25421 CNV Loss 19812545

Relevant External Links for ZNF574 Gene

HapMap Linkage Disequilibrium report
ZNF574

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF574 Gene

Disorders for ZNF574 Gene

No disorders were found for ZNF574 Gene.

No data available for UniProtKB/Swiss-Prot for ZNF574 Gene

Publications for ZNF574 Gene

  1. A probability-based approach for high-throughput protein phosphorylation analysis and site localization. (PMID: 16964243) Beausoleil S.A. … Gygi S.P. (Nat. Biotechnol. 2006) 3 4
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  5. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3

Products for ZNF574 Gene

Sources for ZNF574 Gene

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