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Aliases for ZNF573 Gene

Aliases for ZNF573 Gene

  • Zinc Finger Protein 573 2 3 5

External Ids for ZNF573 Gene

Previous GeneCards Identifiers for ZNF573 Gene

  • GC19M042922
  • GC19M042923
  • GC19M038229
  • GC19M034678

Summaries for ZNF573 Gene

GeneCards Summary for ZNF573 Gene

ZNF573 (Zinc Finger Protein 573) is a Protein Coding gene. Among its related pathways are Gene Expression. GO annotations related to this gene include nucleic acid binding and transcription factor activity, sequence-specific DNA binding. An important paralog of this gene is ZNF607.

UniProtKB/Swiss-Prot for ZNF573 Gene

  • May be involved in transcriptional regulation.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF573 Gene

Genomics for ZNF573 Gene

Regulatory Elements for ZNF573 Gene

Enhancers for ZNF573 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around ZNF573 on UCSC Golden Path with GeneCards custom track

Promoters for ZNF573 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around ZNF573 on UCSC Golden Path with GeneCards custom track

Genomic Location for ZNF573 Gene

37,735,131 bp from pter
37,817,300 bp from pter
82,170 bases
Minus strand

Genomic View for ZNF573 Gene

Genes around ZNF573 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF573 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF573 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF573 Gene

Proteins for ZNF573 Gene

  • Protein details for ZNF573 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Zinc finger protein 573
    Protein Accession:
    Secondary Accessions:
    • B7WPE1
    • K7EJ45
    • Q6P1P1
    • Q7Z7Q3
    • Q8N2Q1
    • Q96BM3
    • Q96NH0

    Protein attributes for ZNF573 Gene

    665 amino acids
    Molecular mass:
    78181 Da
    Quaternary structure:
    No Data Available
    • Sequence=AAH42170.2; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305};

    Alternative splice isoforms for ZNF573 Gene


neXtProt entry for ZNF573 Gene

Proteomics data for ZNF573 Gene at MOPED

Post-translational modifications for ZNF573 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for ZNF573 Gene

Domains & Families for ZNF573 Gene

Gene Families for ZNF573 Gene

Protein Domains for ZNF573 Gene

Suggested Antigen Peptide Sequences for ZNF573 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Contains 1 KRAB domain.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 19 C2H2-type zinc fingers.
  • Contains 1 KRAB domain.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 19 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF573: view

Function for ZNF573 Gene

Molecular function for ZNF573 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.
genes like me logo Genes that share phenotypes with ZNF573: view

Animal Model Products

CRISPR Products

miRNA for ZNF573 Gene

miRTarBase miRNAs that target ZNF573

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF573 Gene

Localization for ZNF573 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF573 Gene

Subcellular locations from

Jensen Localization Image for ZNF573 Gene COMPARTMENTS Subcellular localization image for ZNF573 gene
Compartment Confidence
nucleus 5
cytosol 3
cytoskeleton 2

No data available for Gene Ontology (GO) - Cellular Components for ZNF573 Gene

Pathways & Interactions for ZNF573 Gene

SuperPathways for ZNF573 Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF573: view

Pathways by source for ZNF573 Gene

2 Reactome pathways for ZNF573 Gene

Interacting Proteins for ZNF573 Gene

Gene Ontology (GO) - Biological Process for ZNF573 Gene


No data available for SIGNOR curated interactions for ZNF573 Gene

Drugs & Compounds for ZNF573 Gene

No Compound Related Data Available

Transcripts for ZNF573 Gene

Unigene Clusters for ZNF573 Gene

Zinc finger protein 573:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF573 Gene

ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9a · 9b · 9c · 9d · 9e · 9f
SP1: - -
SP2: - - -
SP3: - - - -
SP4: - - - - -
SP5: - - - - - -
SP6: - - - - -

Relevant External Links for ZNF573 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ZNF573 Gene

mRNA expression in normal human tissues for ZNF573 Gene

Protein differential expression in normal tissues from HIPED for ZNF573 Gene

This gene is overexpressed in Ovary (21.2), Plasma (19.1), Spleen (17.9), and Testis (9.8).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MOPED, and MaxQB for ZNF573 Gene

SOURCE GeneReport for Unigene cluster for ZNF573 Gene Hs.531262

genes like me logo Genes that share expression patterns with ZNF573: view

Protein tissue co-expression partners for ZNF573 Gene

- Elite partner

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ZNF573 Gene

Orthologs for ZNF573 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF573 Gene

Organism Taxonomy Gene Similarity Type Details
(Canis familiaris)
Mammalia ZNF573 35
  • 84.4 (n)
  • 77.66 (a)
(Bos Taurus)
Mammalia -- 36
  • 53 (a)
(Monodelphis domestica)
Mammalia -- 36
  • 47 (a)
Species with no ortholog for ZNF573:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF573 Gene

Gene Tree for ZNF573 (if available)
Gene Tree for ZNF573 (if available)

Paralogs for ZNF573 Gene

(555) SIMAP similar genes for ZNF573 Gene using alignment to 8 proteins:

genes like me logo Genes that share paralogs with ZNF573: view

Variants for ZNF573 Gene

Sequence variations from dbSNP and Humsavar for ZNF573 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
rs3752365 -, - 37,739,819(+) CCTTC(C/G/T)CACAC reference, missense
rs766395 -- 37,739,932(-) ACTGG(G/T)GAGAA reference, synonymous-codon
rs12975895 -- 37,742,599(+) taaat(C/G)gtgct intron-variant
rs12979306 -- 37,769,752(+) aaaag(A/T)aaaGA intron-variant
rs8101476 -- 37,758,378(+) ggtgg(A/G)tcacc intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF573 Gene

Variant ID Type Subtype PubMed ID
nsv833820 CNV Loss 17160897
esv2718522 CNV Deletion 23290073
esv2718523 CNV Deletion 23290073
esv2718524 CNV Deletion 23290073
esv2718525 CNV Deletion 23290073
esv2718526 CNV Deletion 23290073
esv1564972 CNV Deletion 17803354
esv2718527 CNV Deletion 23290073
esv2718528 CNV Deletion 23290073
esv2437108 CNV Deletion 19546169

Variation tolerance for ZNF573 Gene

Residual Variation Intolerance Score: 48.4% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 6.61; 78.17% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for ZNF573 Gene

Disorders for ZNF573 Gene

Relevant External Links for ZNF573

Genetic Association Database (GAD)
Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for ZNF573 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF573 Gene

Publications for ZNF573 Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 67
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  3. Ubiquitin-mediated proteolysis of HuR by heat shock. (PMID: 19322201) Abdelmohsen K. … Gorospe M. (EMBO J. 2009) 3
  4. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3

Products for ZNF573 Gene

Sources for ZNF573 Gene