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Aliases for ZNF572 Gene

Aliases for ZNF572 Gene

  • Zinc Finger Protein 572 2 3 5

External Ids for ZNF572 Gene

Previous GeneCards Identifiers for ZNF572 Gene

  • GC08P125943
  • GC08P126054
  • GC08P121308
  • GC08P125985
  • GC08P124973

Summaries for ZNF572 Gene

GeneCards Summary for ZNF572 Gene

ZNF572 (Zinc Finger Protein 572) is a Protein Coding gene. An important paralog of this gene is ZNF629.

UniProtKB/Swiss-Prot for ZNF572 Gene

  • May be involved in transcriptional regulation.

Additional gene information for ZNF572 Gene

No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF572 Gene

Genomics for ZNF572 Gene

GeneHancer (GH) Regulatory Elements for ZNF572 Gene

Promoters and enhancers for ZNF572 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH08I124972 Promoter/Enhancer 2 EPDnew Ensembl ENCODE 550.1 +125.0 125026 1.8 ARID4B SIN3A DMAP1 ZBTB7B YY1 POLR2B E2F8 ZNF143 ZHX2 MXD4 ZNF572 TRMT12 WASHC5-AS1 RNF139 PIR59755 PIR40025
GH08I124846 Enhancer 1.4 Ensembl ENCODE dbSUPER 550.8 -0.5 -459 3.1 PKNOX1 ATF1 ARNT YY1 TCF12 ZNF766 ATF7 RUNX3 CAVIN1 JUNB ZNF572 LINC00964 MTSS1 LOC105375744 SQLE LOC105375743 MIR4662B
GH08I124194 Enhancer 1.7 FANTOM5 Ensembl ENCODE dbSUPER 19.7 -650.2 -650203 8.7 HDGF PKNOX1 ARNT NEUROD1 SIN3A FEZF1 YBX1 ZNF2 ZBTB7B IRF4 TRMT12 FAM91A1 TMEM65 WASHC5 WASHC5-AS1 RNF139-AS1 ZNF572 RNF139 NSMCE2 FER1L6-AS2
GH08I124685 Enhancer 1.4 Ensembl ENCODE dbSUPER 19.8 -160.5 -160533 5.7 HDGF PKNOX1 FOXA2 ZFP64 ARID4B SIN3A YBX1 FEZF1 ZNF48 ETS1 FAM91A1 WASHC5-AS1 ZNF572 TRMT12 MTSS1 WASHC5 RNF139 TATDN1 NDUFB9 GC08P124718
GH08I124592 Enhancer 1.5 FANTOM5 Ensembl ENCODE dbSUPER 12.3 -253.6 -253641 4.3 RB1 ARID4B BATF ZNF48 RAD21 RFX5 ARID2 ZNF143 ATF7 BCLAF1 MTSS1 ZNF572 NDUFB9 TATDN1 LOC105375744 SQLE TRMT12 NSMCE2 RNF139 WASHC5
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around ZNF572 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the ZNF572 gene promoter:

Genomic Locations for ZNF572 Gene

Genomic Locations for ZNF572 Gene
chr8:124,848,552-124,979,511
(GRCh38/hg38)
Size:
130,960 bases
Orientation:
Plus strand
chr8:125,985,539-125,991,631
(GRCh37/hg19)

Genomic View for ZNF572 Gene

Genes around ZNF572 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF572 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF572 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF572 Gene

Proteins for ZNF572 Gene

  • Protein details for ZNF572 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q7Z3I7-ZN572_HUMAN
    Recommended name:
    Zinc finger protein 572
    Protein Accession:
    Q7Z3I7
    Secondary Accessions:
    • A1L4E9
    • A1L4F1
    • Q8N1Q0

    Protein attributes for ZNF572 Gene

    Size:
    529 amino acids
    Molecular mass:
    61238 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZNF572 Gene

Post-translational modifications for ZNF572 Gene

No Post-translational modifications

Other Protein References for ZNF572 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ZNF572 Gene

Domains & Families for ZNF572 Gene

Gene Families for ZNF572 Gene

HGNC:
Human Protein Atlas (HPA):
  • Predicted intracellular proteins
  • Transcription factors

Protein Domains for ZNF572 Gene

Suggested Antigen Peptide Sequences for ZNF572 Gene

Graphical View of Domain Structure for InterPro Entry

Q7Z3I7

UniProtKB/Swiss-Prot:

ZN572_HUMAN :
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
genes like me logo Genes that share domains with ZNF572: view

Function for ZNF572 Gene

Molecular function for ZNF572 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Phenotypes From GWAS Catalog for ZNF572 Gene

Gene Ontology (GO) - Molecular Function for ZNF572 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
GO:0003700 DNA binding transcription factor activity IBA --
GO:0005515 protein binding IPI 25416956
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF572: view

Phenotypes for ZNF572 Gene

GenomeRNAi human phenotypes for ZNF572:
genes like me logo Genes that share phenotypes with ZNF572: view

miRNA for ZNF572 Gene

miRTarBase miRNAs that target ZNF572

Clone Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF572 Gene

Localization for ZNF572 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF572 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZNF572 gene
Compartment Confidence
nucleus 5
cytosol 2

Subcellular locations from the

Human Protein Atlas (HPA)
  • Nuclear speckles (2)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for ZNF572 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IDA --
genes like me logo Genes that share ontologies with ZNF572: view

Pathways & Interactions for ZNF572 Gene

SuperPathways for ZNF572 Gene

No Data Available

Gene Ontology (GO) - Biological Process for ZNF572 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IBA --
genes like me logo Genes that share ontologies with ZNF572: view

No data available for Pathways by source and SIGNOR curated interactions for ZNF572 Gene

Drugs & Compounds for ZNF572 Gene

No Compound Related Data Available

Transcripts for ZNF572 Gene

mRNA/cDNA for ZNF572 Gene

(1) REFSEQ mRNAs :
(4) Additional mRNA sequences :
(7) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ZNF572 Gene

Zinc finger protein 572:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF572 Gene

No ASD Table

Relevant External Links for ZNF572 Gene

GeneLoc Exon Structure for
ZNF572
ECgene alternative splicing isoforms for
ZNF572

Expression for ZNF572 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ZNF572 Gene

Protein differential expression in normal tissues from HIPED for ZNF572 Gene

This gene is overexpressed in Urine (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for ZNF572 Gene



Protein tissue co-expression partners for ZNF572 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of ZNF572 Gene:

ZNF572

SOURCE GeneReport for Unigene cluster for ZNF572 Gene:

Hs.175350
genes like me logo Genes that share expression patterns with ZNF572: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZNF572 Gene

Orthologs for ZNF572 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZNF572 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF572 33 34
  • 99.29 (n)
dog
(Canis familiaris)
Mammalia ZNF572 33 34
  • 86.98 (n)
cow
(Bos Taurus)
Mammalia ZNF572 33 34
  • 85.82 (n)
oppossum
(Monodelphis domestica)
Mammalia ZNF572 34
  • 70 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia -- 34
  • 60 (a)
ManyToMany
-- 34
  • 60 (a)
ManyToMany
-- 34
  • 59 (a)
ManyToMany
-- 34
  • 58 (a)
ManyToMany
-- 34
  • 58 (a)
ManyToMany
-- 34
  • 57 (a)
ManyToMany
-- 34
  • 57 (a)
ManyToMany
-- 34
  • 57 (a)
ManyToMany
-- 34
  • 56 (a)
ManyToMany
-- 34
  • 56 (a)
ManyToMany
-- 34
  • 56 (a)
ManyToMany
-- 34
  • 56 (a)
ManyToMany
-- 34
  • 55 (a)
ManyToMany
-- 34
  • 55 (a)
ManyToMany
-- 34
  • 55 (a)
ManyToMany
-- 34
  • 55 (a)
ManyToMany
-- 34
  • 54 (a)
ManyToMany
-- 34
  • 54 (a)
ManyToMany
-- 34
  • 54 (a)
ManyToMany
-- 34
  • 53 (a)
ManyToMany
-- 34
  • 53 (a)
ManyToMany
-- 34
  • 53 (a)
ManyToMany
-- 34
  • 53 (a)
ManyToMany
-- 34
  • 53 (a)
ManyToMany
-- 34
  • 53 (a)
ManyToMany
-- 34
  • 53 (a)
ManyToMany
-- 34
  • 52 (a)
ManyToMany
-- 34
  • 52 (a)
ManyToMany
-- 34
  • 52 (a)
ManyToMany
-- 34
  • 51 (a)
ManyToMany
-- 34
  • 51 (a)
ManyToMany
-- 34
  • 50 (a)
ManyToMany
-- 34
  • 50 (a)
ManyToMany
-- 34
  • 50 (a)
ManyToMany
-- 34
  • 50 (a)
ManyToMany
-- 34
  • 49 (a)
ManyToMany
-- 34
  • 49 (a)
ManyToMany
-- 34
  • 49 (a)
ManyToMany
-- 34
  • 49 (a)
ManyToMany
-- 34
  • 48 (a)
ManyToMany
-- 34
  • 47 (a)
ManyToMany
-- 34
  • 46 (a)
ManyToMany
-- 34
  • 45 (a)
ManyToMany
-- 34
  • 44 (a)
ManyToMany
-- 34
  • 43 (a)
ManyToMany
-- 34
  • 41 (a)
ManyToMany
-- 34
  • 31 (a)
ManyToMany
-- 34
  • 30 (a)
ManyToMany
Species where no ortholog for ZNF572 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF572 Gene

ENSEMBL:
Gene Tree for ZNF572 (if available)
TreeFam:
Gene Tree for ZNF572 (if available)

Paralogs for ZNF572 Gene

Paralogs for ZNF572 Gene

(500) SIMAP similar genes for ZNF572 Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with ZNF572: view

Variants for ZNF572 Gene

Sequence variations from dbSNP and Humsavar for ZNF572 Gene

SNP ID Clin Chr 08 pos Variation AA Info Type
VAR_035591 A colorectal cancer sample p.Cys512Phe
rs1000045801 -- 124,972,648(+) C/T upstream_transcript_variant
rs1000312373 -- 124,972,854(+) A/G upstream_transcript_variant
rs1000537200 -- 124,977,836(+) C/T coding_sequence_variant, missense_variant
rs1000849748 -- 124,976,971(+) C/T coding_sequence_variant, missense_variant

Variation tolerance for ZNF572 Gene

Residual Variation Intolerance Score: 58.7% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 7.02; 80.15% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for ZNF572 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ZNF572

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for ZNF572 Gene

Disorders for ZNF572 Gene

Additional Disease Information for ZNF572

No disorders were found for ZNF572 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF572 Gene

Publications for ZNF572 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 58
  2. Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation. (PMID: 28112733) Hendriks IA … Nielsen ML (Nature structural & molecular biology 2017) 4 58
  3. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T … Vidal M (Cell 2014) 3 58
  4. The full-ORF clone resource of the German cDNA Consortium. (PMID: 17974005) Bechtel S … Schupp I (BMC genomics 2007) 4 58
  5. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K … Sugano S (Genome research 2006) 3 58

Products for ZNF572 Gene

Sources for ZNF572 Gene

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