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Aliases for ZNF570 Gene

Aliases for ZNF570 Gene

  • Zinc Finger Protein 570 2 3

External Ids for ZNF570 Gene

Previous GeneCards Identifiers for ZNF570 Gene

  • GC19P042653
  • GC19P042654
  • GC19P037959
  • GC19P034410

Summaries for ZNF570 Gene

GeneCards Summary for ZNF570 Gene

ZNF570 (Zinc Finger Protein 570) is a Protein Coding gene. Among its related pathways are Gene Expression and Gene Expression. An important paralog of this gene is ZNF529.

UniProtKB/Swiss-Prot for ZNF570 Gene

  • May be involved in transcriptional regulation

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF570 Gene

Genomics for ZNF570 Gene

Regulatory Elements for ZNF570 Gene

Genomic Location for ZNF570 Gene

Start:
37,467,585 bp from pter
End:
37,488,652 bp from pter
Size:
21,068 bases
Orientation:
Plus strand

Genomic View for ZNF570 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZNF570 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF570 Gene

Proteins for ZNF570 Gene

  • Protein details for ZNF570 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q96NI8-ZN570_HUMAN
    Recommended name:
    Zinc finger protein 570
    Protein Accession:
    Q96NI8
    Secondary Accessions:
    • A1L472
    • B4DMP1

    Protein attributes for ZNF570 Gene

    Size:
    536 amino acids
    Molecular mass:
    62330 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ZNF570 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZNF570 Gene

Proteomics data for ZNF570 Gene at MOPED

Post-translational modifications for ZNF570 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF570 Gene

No data available for DME Specific Peptides for ZNF570 Gene

Domains for ZNF570 Gene

Gene Families for ZNF570 Gene

HGNC:
  • ZNF :Zinc fingers, C2H2-type

Suggested Antigen Peptide Sequences for ZNF570 Gene

Graphical View of Domain Structure for InterPro Entry

Q96NI8

UniProtKB/Swiss-Prot:

ZN570_HUMAN :
  • Q96NI8
Domain:
  • Contains 1 KRAB domain.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 11 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF570: view

Function for ZNF570 Gene

Molecular function for ZNF570 Gene

UniProtKB/Swiss-Prot Function: May be involved in transcriptional regulation

Gene Ontology (GO) - Molecular Function for ZNF570 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding --
GO:0003677 DNA binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF570: view

Phenotypes for ZNF570 Gene

GenomeRNAi human phenotypes for ZNF570:
genes like me logo Genes that share phenotypes with ZNF570: view

No data available for Enzyme Numbers (IUBMB) , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for ZNF570 Gene

Localization for ZNF570 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF570 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF570 Gene COMPARTMENTS Subcellular localization image for ZNF570 gene
Compartment Confidence
nucleus 3
cytoskeleton 1
mitochondrion 1
peroxisome 1

Gene Ontology (GO) - Cellular Components for ZNF570 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF570: view

Pathways for ZNF570 Gene

SuperPathways for ZNF570 Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF570: view

Pathways by source for ZNF570 Gene

2 Reactome pathways for ZNF570 Gene

Interacting Proteins for ZNF570 Gene

Gene Ontology (GO) - Biological Process for ZNF570 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF570: view

Transcripts for ZNF570 Gene

mRNA/cDNA for ZNF570 Gene

(5) Additional mRNA sequences :
(9) REFSEQ mRNAs :
(6) Selected AceView cDNA sequences:
(7) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ZNF570 Gene

Zinc finger protein 570:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF570 Gene

ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7a · 7b · 7c
SP1: - -
SP2: -
SP3: - - -
SP4: -

Relevant External Links for ZNF570 Gene

GeneLoc Exon Structure for
ZNF570
ECgene alternative splicing isoforms for
ZNF570

Expression for ZNF570 Gene

mRNA expression in normal human tissues for ZNF570 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for ZNF570 Gene

SOURCE GeneReport for Unigene cluster for ZNF570 Gene Hs.350875

genes like me logo Genes that share expressions with ZNF570: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ZNF570 Gene

Orthologs for ZNF570 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZNF570 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF570 35
  • 99.69 (n)
  • 100 (a)
ZNF570 36
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia ZNF570 35
  • 92.09 (n)
  • 91.03 (a)
ZNF570 36
  • 91 (a)
OneToOne
dog
(Canis familiaris)
Mammalia ZNF570 36
  • 93 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Zfp78 36
  • 53 (a)
ManyToMany
rat
(Rattus norvegicus)
Mammalia LOC100359523 35
  • 80.64 (n)
  • 80.04 (a)
zebrafish
(Danio rerio)
Actinopterygii LOC101883198 35
  • 56.6 (n)
  • 50.31 (a)
Species with no ortholog for ZNF570:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ZNF570 Gene

ENSEMBL:
Gene Tree for ZNF570 (if available)
TreeFam:
Gene Tree for ZNF570 (if available)

Paralogs for ZNF570 Gene

Selected SIMAP similar genes for ZNF570 Gene using alignment to 7 proteins:

genes like me logo Genes that share paralogs with ZNF570: view

Variants for ZNF570 Gene

Sequence variations from dbSNP and Humsavar for ZNF570 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type MAF
rs1236810 -- 37,475,759(-) ATATT(C/T)GTACT intron-variant
rs2081095 -- 37,473,896(-) atgtc(A/T)atcac intron-variant
rs2081096 -- 37,473,798(-) TTACT(C/T)TCTTC intron-variant
rs4801803 -- 37,476,021(+) ATCTT(C/T)TTGCA intron-variant
rs4802702 -- 37,483,897(+) ATGTG(A/G)GACTG reference, missense, utr-variant-5-prime

Structural Variations from Database of Genomic Variants (DGV) for ZNF570 Gene

Variant ID Type Subtype PubMed ID
dgv1081e1 CNV Complex 17122850
nsv833819 CNV Gain 17160897
esv2675530 CNV Deletion 23128226
esv2718519 CNV Deletion 23290073
esv28496 CNV Loss 19812545

Relevant External Links for ZNF570 Gene

HapMap Linkage Disequilibrium report
ZNF570

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF570 Gene

Disorders for ZNF570 Gene

No disorders were found for ZNF570 Gene.

No data available for UniProtKB/Swiss-Prot for ZNF570 Gene

Publications for ZNF570 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  2. Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition. (PMID: 22505724) Udeshi N.D. … Carr S.A. (Mol. Cell Proteomics 2012) 3
  3. The DNA sequence and biology of human chromosome 19. (PMID: 15057824) Grimwood J. … Lucas S.M. (Nature 2004) 4
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for ZNF570 Gene

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat
  • QIAGEN qRT-PCR Assays for microRNAs that regulate ZNF570
    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat
    • Predesigned siRNA for gene silencing in human,mouse,rat for ZNF570
    • Block miRNA regulation of ZNF570 using miScript Target Protectors

    Sources for ZNF570 Gene

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