ZNF567 Gene
protein-coding GIFtS: 48
GCID: GC19P037180
|
|
zinc finger protein 567
| |
Aliases
for ZNF567 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Zinc Finger Protein 5671 2 | | MGC455861 |
Export aliases for ZNF567 gene to outside databasesPrevious GC identifers: GC19P041872 GC19P033648 |
Summaries
for ZNF567 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
UniProtKB/Swiss-Prot: ZN567_HUMAN, Q8N184Function: May be involved in transcriptional regulation
|
Genomic Views
for ZNF567 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000019.9 NC_018930.1 NT_011109.16
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the ZNF567 gene promoter:
PPAR-alpha RP58
Other transcription factors
Search SABiosciences Chromatin IP Primers for ZNF567
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZNF567 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 19q13.12 Ensembl cytogenetic band: 19q13.12 HGNC chromosome: 19ZNF567 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 19 GeneLoc Exon Structure GeneLoc location for GC19P037180: view genomic region
(about GC identifiers)
Start:
|
37,178,514 bp from pter |
End:
|
37,218,603 bp from pter |
Size:
|
40,090 bases |
Orientation:
|
plus strand |
|
Proteins
for ZNF567 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: ZN567_HUMAN, Q8N184 (See
protein sequence)Recommended Name: Zinc finger protein 567 Size: 647 amino acids; 75164 Da
Subcellular location: Nucleus (Potential)
Secondary accessions: B3KX49 Q6N044Alternative splicing: 3 isoforms: Q8N184-3 Q8N184-1 Q8N184-2 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for ZNF567: NX_Q8N184
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q8N184
ZNF567 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_689816.2
ENSEMBL proteins: ENSP00000441838 ENSP00000353957 ENSP00000467712 ENSP00000467379 ENSP00000466458 ENSP00000468750 ENSP00000376003 Reactome Protein details: Q8N184
Human Recombinant Protein Products:
Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table
ZNF567 for ontologies About GeneDecksing
ZNF567 Antibody Products:
Assay Products for ZNF567: |
Protein
Domains /
Families
for ZNF567 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ZNF567 for domains About GeneDecksing
4 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q8N184ProtoNet protein and cluster: Q8N184 1 Blocks protein family: IPB001909 KRAB box
UniProtKB/Swiss-Prot: ZN567_HUMAN, Q8N184Similarity: Belongs to the krueppel C2H2-type zinc-finger protein familySimilarity: Contains 15 C2H2-type zinc fingersSimilarity: Contains 1 KRAB domain |
Function
for ZNF567 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: ZN567_HUMAN, Q8N184Function: May be involved in transcriptional regulation
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF567 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF567
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
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Synthesis Service for ZNF567 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF567 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF567 |
Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table
ZNF567 for ontologies About GeneDecksing
|
Pathways & Interactions
for ZNF567 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Generic Transcription Pathway | |
Pathway sources
See GeneCards unified pathways
Show all pathways
2 
Reactome Pathways for ZNF567
ZNF567 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ZNF567
STRING Interaction
Network Preview (showing 2 interactants - click image to see more details)
2 Interacting proteins for ZNF567 (Q8N1842, 3 ENSP000003539574) via UniProtKB, MINT, STRING, and/or I2DAbout this table
Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006351 | transcription, DNA-dependent |
IEA | -- | | GO:0006355 | regulation of transcription, DNA-dependent |
IEA | -- |
ZNF567 for ontologies About GeneDecksing
|
Drugs & Compounds
for ZNF567 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for ZNF567
Search CenterWatch for drugs/clinical trials and news about ZNF567 / ZN567
|
Transcripts
for ZNF567 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for ZNF567 gene: NM_152603.2 Unigene Cluster for ZNF567: Zinc finger protein 567 Hs.412517 [show with all ESTs]Unigene Representative Sequence: AK1266918 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000590392 ENST00000536254(uc002oeo.1 uc010xtk.1) ENST00000360729(uc010xtl.2 uc002oep.4)
ENST00000588311 ENST00000585696 ENST00000589264 ENST00000591308 ENST00000392163(uc002oeq.1)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF567 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF567
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: ZNF567 (NM_152603) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ZNF567 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF567 |
Additional cDNA sequence: AK093034.1 AK126691.1 AK298556.1 AK303326.1 AK313647.1 BC033849.2 BX640706.1 5 DOTS entries: DT.100020362 DT.40124482 DT.100020363 DT.97823669 DT.65287473 24/37 AceView cDNA sequences (see all 37): AI805475 BE882972 BE501233 BE549839 NM_152603 AI670951 AI696232 BC033849 AW512510 BQ923822 AK093034 AI820881 AK126691 AX747871 AU121463 AW439492 AI572781 BX640706 AA742659 BM973060 CD357551 AL701314 AW003457 BI829499
GeneLoc Exon Structure
3 Alternative Splicing Database (ASD) splice patterns (SP) for ZNF567 About this scheme
| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3a | · | 3b | ^ | 4a | · | 4b | · | 4c | ^ | 5 |
|---|
|
| SP1: | | | | | | | | | | | | | | | - | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for ZNF567
|
Expression
for ZNF567 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ZNF567 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TGGCAGTAGT
About this image
See ZNF567 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for ZNF567
SOURCE GeneReport for Unigene cluster: Hs.412517
SABiosciences Custom PCR Arrays for ZNF567
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZNF567
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat ZNF567 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZNF567 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZNF567 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF567 |
Orthologs
for ZNF567 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for ZNF567 gene from 2/6 species (see all 6) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
mouse
(Mus musculus) |
Mammalia |
Zfp3001 , 5 |
zinc finger protein 3001, 5 |
62.92(n)1
51.07(a)1 |
|
X (16.59 cM)5
2453681 NM_183185.31 NP_899008.21
210791745 |
tropical clawed frog
(Xenopus tropicalis) |
Amphibia |
BX710168.12 |
-- |
75.2(n) |
|
BX710168.1 |
ENSEMBL Gene Tree for ZNF567 (if available)
TreeFam Gene Tree for ZNF567 (if available) |
Paralogs
for ZNF567 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for ZNF567 gene
- ZNF3342 ENSG000002673602 ZNF7822 ZNF122 ZNF5102 ZNF33A2 ZNF7172 RBAK2
- ZNF487P2 ZNF37A2 ZNF2482 ZNF33B2 ZNF3822
18/538 SIMAP similar genes for ZNF567 using alignment to 4 protein entries: ZN567_HUMAN (see all proteins)
(see all similar genes):ZNF78L1 ZFS-5 kr-znf3 DKFZp666C237 ZNF684 ZNF696
ZNF84 DKFZp313M0722 HZF36 ZNF146 ZNF323 ZNF56
ZNF826P ZNF MGC12518 ZFP90 ZNF239 ZNF436
ZNF567 for paralogs About GeneDecksing
|
Genomic Variants
for ZNF567 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 19 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for ZNF567 (37178514 - 37218603 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 2 variations for ZNF567
2 CNVs: 10553 9306 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ZNF567 |
|
Disorders
/ Diseases
for ZNF567 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications
for ZNF567 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ZNF567 gene integrated from 9 sources:
(articles sorted by number of sources associating them with ZNF567) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (2002)
- A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
- An atlas of combinatorial transcriptional regulation in mouse and man. (PubMed id 20211142)1 Ravasi T....Hayashizaki Y. (2010)
- The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (2007)
- Towards a proteome-scale map of the human protein-protein interaction network. (PubMed id 16189514)1 Rual J.F....Vidal M. (2005)
|
External Searches for ZNF567 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing ZNF567 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing ZNF567 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing ZNF567 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for ZNF567 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for ZNF567 gene:
Search GeneIP for patents involving ZNF567
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for ZNF567 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for ZNF567 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ZNF567 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZNF567 | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for ZNF567 | | OriGene 3'-UTR Clone for ZNF567 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF567 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF567 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for ZNF567 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for ZNF567 | | OriGene Custom Protein Services for ZNF567 | | | OriGene Custom Immunoassay Development | | |
| |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ZNF567 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ZNF567 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZNF567 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ZNF567 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZNF567 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZNF567 |
| |
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| |  |  |  |  | | | | |
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 | | | ZNF567 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF567 |
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| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF567 |
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