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Aliases for ZNF567 Gene

Aliases for ZNF567 Gene

  • Zinc Finger Protein 567 2 3 5

External Ids for ZNF567 Gene

Previous GeneCards Identifiers for ZNF567 Gene

  • GC19P041872
  • GC19P037180
  • GC19P033648

Summaries for ZNF567 Gene

GeneCards Summary for ZNF567 Gene

ZNF567 (Zinc Finger Protein 567) is a Protein Coding gene. Among its related pathways are Gene Expression. GO annotations related to this gene include nucleic acid binding. An important paralog of this gene is ZNF248.

UniProtKB/Swiss-Prot for ZNF567 Gene

  • May be involved in transcriptional regulation.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF567 Gene

Genomics for ZNF567 Gene

Regulatory Elements for ZNF567 Gene

Enhancers for ZNF567 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around ZNF567 on UCSC Golden Path with GeneCards custom track

Promoters for ZNF567 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around ZNF567 on UCSC Golden Path with GeneCards custom track

Transcription factor binding sites by QIAGEN in the ZNF567 gene promoter:

Genomic Location for ZNF567 Gene

Chromosome:
19
Start:
36,687,564 bp from pter
End:
36,727,701 bp from pter
Size:
40,138 bases
Orientation:
Plus strand

Genomic View for ZNF567 Gene

Genes around ZNF567 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF567 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF567 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF567 Gene

Proteins for ZNF567 Gene

  • Protein details for ZNF567 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8N184-ZN567_HUMAN
    Recommended name:
    Zinc finger protein 567
    Protein Accession:
    Q8N184
    Secondary Accessions:
    • B3KX49
    • Q6N044

    Protein attributes for ZNF567 Gene

    Size:
    647 amino acids
    Molecular mass:
    75164 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ZNF567 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZNF567 Gene

Proteomics data for ZNF567 Gene at MOPED

Post-translational modifications for ZNF567 Gene

  • Ubiquitination at Lys 55
  • Modification sites at PhosphoSitePlus

No data available for DME Specific Peptides for ZNF567 Gene

Domains & Families for ZNF567 Gene

Gene Families for ZNF567 Gene

Protein Domains for ZNF567 Gene

Suggested Antigen Peptide Sequences for ZNF567 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q8N184

UniProtKB/Swiss-Prot:

ZN567_HUMAN :
  • Contains 1 KRAB domain.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 15 C2H2-type zinc fingers.
Domain:
  • Contains 1 KRAB domain.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 15 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF567: view

Function for ZNF567 Gene

Molecular function for ZNF567 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Gene Ontology (GO) - Molecular Function for ZNF567 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding IEA --
GO:0005515 protein binding IPI 25416956
GO:0044212 transcription regulatory region DNA binding IBA --
genes like me logo Genes that share ontologies with ZNF567: view
genes like me logo Genes that share phenotypes with ZNF567: view

Animal Model Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF567 Gene

Localization for ZNF567 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF567 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF567 Gene COMPARTMENTS Subcellular localization image for ZNF567 gene
Compartment Confidence
nucleus 5
cytosol 3
mitochondrion 2

No data available for Gene Ontology (GO) - Cellular Components for ZNF567 Gene

Pathways & Interactions for ZNF567 Gene

SuperPathways for ZNF567 Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF567: view

Pathways by source for ZNF567 Gene

2 Reactome pathways for ZNF567 Gene

Gene Ontology (GO) - Biological Process for ZNF567 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000122 negative regulation of transcription from RNA polymerase II promoter IBA --
GO:0045944 positive regulation of transcription from RNA polymerase II promoter IBA --
genes like me logo Genes that share ontologies with ZNF567: view

No data available for SIGNOR curated interactions for ZNF567 Gene

Drugs & Compounds for ZNF567 Gene

No Compound Related Data Available

Transcripts for ZNF567 Gene

Unigene Clusters for ZNF567 Gene

Zinc finger protein 567:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF567 Gene

ExUns: 1a · 1b ^ 2 ^ 3a · 3b ^ 4a · 4b · 4c ^ 5
SP1: -
SP2:
SP3:

Relevant External Links for ZNF567 Gene

GeneLoc Exon Structure for
ZNF567
ECgene alternative splicing isoforms for
ZNF567

Expression for ZNF567 Gene

mRNA expression in normal human tissues for ZNF567 Gene

SOURCE GeneReport for Unigene cluster for ZNF567 Gene Hs.412517

genes like me logo Genes that share expression patterns with ZNF567: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for ZNF567 Gene

Orthologs for ZNF567 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZNF567 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia ZNF567 35
  • 90.69 (n)
  • 90.26 (a)
ZNF567 36
  • 86 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Zfp300 35
  • 61.76 (n)
  • 47.14 (a)
Zfp300 16
Zfp719 36
  • 30 (a)
ManyToMany
chimpanzee
(Pan troglodytes)
Mammalia ZNF567 35
  • 99.73 (n)
  • 99.51 (a)
ZNF567 36
  • 95 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Zfp300 35
  • 60.53 (n)
  • 47.7 (a)
lizard
(Anolis carolinensis)
Reptilia -- 36
  • 32 (a)
OneToMany
Species with no ortholog for ZNF567:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF567 Gene

ENSEMBL:
Gene Tree for ZNF567 (if available)
TreeFam:
Gene Tree for ZNF567 (if available)

Paralogs for ZNF567 Gene

(545) SIMAP similar genes for ZNF567 Gene using alignment to 4 proteins:

genes like me logo Genes that share paralogs with ZNF567: view

Variants for ZNF567 Gene

Sequence variations from dbSNP and Humsavar for ZNF567 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
rs8100465 -- 36,700,927(+) ttcag(C/T)tctgc intron-variant
rs8102705 -- 36,697,408(+) cctgt(C/T)atatg intron-variant
rs12984462 -- 36,691,259(+) gctca(A/G)gtgat intron-variant, upstream-variant-2KB
rs8104992 -- 36,712,100(+) ggagt(C/G)cagtg intron-variant
rs13345382 -- 36,718,161(+) GAACA(G/T)CTGGA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF567 Gene

Variant ID Type Subtype PubMed ID
nsv833817 CNV Loss 17160897
nsv469794 CNV Complex 16826518
esv34384 CNV Loss 17911159
nsv817833 CNV Loss 17921354
nsv470139 CNV Loss 18288195
nsv911649 CNV Loss 21882294

Variation tolerance for ZNF567 Gene

Residual Variation Intolerance Score: 15.4% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 3.04; 50.33% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for ZNF567 Gene

Disorders for ZNF567 Gene

Relevant External Links for ZNF567

Genetic Association Database (GAD)
ZNF567
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ZNF567

No disorders were found for ZNF567 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF567 Gene

Publications for ZNF567 Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 67
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  3. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3
  4. Next-generation sequencing to generate interactome datasets. (PMID: 21516116) Yu H. … Vidal M. (Nat. Methods 2011) 3
  5. An atlas of combinatorial transcriptional regulation in mouse and man. (PMID: 20211142) Ravasi T. … Hayashizaki Y. (Cell 2010) 3

Products for ZNF567 Gene

Sources for ZNF567 Gene

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