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Aliases for ZNF566 Gene

Aliases for ZNF566 Gene

  • Zinc Finger Protein 566 2 3

External Ids for ZNF566 Gene

Previous GeneCards Identifiers for ZNF566 Gene

  • GC19M041629
  • GC19M041631
  • GC19M036936
  • GC19M033404

Summaries for ZNF566 Gene

GeneCards Summary for ZNF566 Gene

ZNF566 (Zinc Finger Protein 566) is a Protein Coding gene. Among its related pathways are Gene Expression and Gene Expression. An important paralog of this gene is ZFP92.

UniProtKB/Swiss-Prot for ZNF566 Gene

  • May be involved in transcriptional regulation

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF566 Gene

Genomics for ZNF566 Gene

Regulatory Elements for ZNF566 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for ZNF566 Gene

Start:
36,445,119 bp from pter
End:
36,489,902 bp from pter
Size:
44,784 bases
Orientation:
Minus strand

Genomic View for ZNF566 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZNF566 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF566 Gene

Proteins for ZNF566 Gene

  • Protein details for ZNF566 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q969W8-ZN566_HUMAN
    Recommended name:
    Zinc finger protein 566
    Protein Accession:
    Q969W8
    Secondary Accessions:
    • B7ZL95
    • Q2M3J1

    Protein attributes for ZNF566 Gene

    Size:
    418 amino acids
    Molecular mass:
    49219 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ZNF566 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZNF566 Gene

Proteomics data for ZNF566 Gene at MOPED

Post-translational modifications for ZNF566 Gene

  • Ubiquitination at Lys62
  • Modification sites at PhosphoSitePlus

No data available for DME Specific Peptides for ZNF566 Gene

Domains for ZNF566 Gene

Gene Families for ZNF566 Gene

HGNC:
  • ZNF :Zinc fingers, C2H2-type

Suggested Antigen Peptide Sequences for ZNF566 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q969W8

UniProtKB/Swiss-Prot:

ZN566_HUMAN :
  • Q969W8
Domain:
  • Contains 1 KRAB domain.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 8 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF566: view

Function for ZNF566 Gene

Molecular function for ZNF566 Gene

UniProtKB/Swiss-Prot Function: May be involved in transcriptional regulation

Gene Ontology (GO) - Molecular Function for ZNF566 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding --
GO:0003677 DNA binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF566: view

Phenotypes for ZNF566 Gene

GenomeRNAi human phenotypes for ZNF566:
genes like me logo Genes that share phenotypes with ZNF566: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZNF566

In Situ Assay Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for ZNF566 Gene

Localization for ZNF566 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF566 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF566 Gene COMPARTMENTS Subcellular localization image for ZNF566 gene
Compartment Confidence
nucleus 4
cytosol 2

Gene Ontology (GO) - Cellular Components for ZNF566 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF566: view

Pathways for ZNF566 Gene

SuperPathways for ZNF566 Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF566: view

Pathways by source for ZNF566 Gene

2 Reactome pathways for ZNF566 Gene

Interacting Proteins for ZNF566 Gene

Gene Ontology (GO) - Biological Process for ZNF566 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF566: view

Transcripts for ZNF566 Gene

Unigene Clusters for ZNF566 Gene

Zinc finger protein 566:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZNF566

Primer Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF566 Gene

ExUns: 1a · 1b · 1c · 1d · 1e ^ 2a · 2b ^ 3a · 3b ^ 4a · 4b ^ 5 ^ 6a · 6b · 6c · 6d · 6e
SP1: - - - -
SP2: - - -
SP3: - - -
SP4: - - - - -
SP5: - - - - -
SP6: - - - - - - -
SP7: -
SP8: - -
SP9: -

Relevant External Links for ZNF566 Gene

GeneLoc Exon Structure for
ZNF566
ECgene alternative splicing isoforms for
ZNF566

Expression for ZNF566 Gene

mRNA expression in normal human tissues for ZNF566 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for ZNF566 Gene

SOURCE GeneReport for Unigene cluster for ZNF566 Gene Hs.533939

genes like me logo Genes that share expressions with ZNF566: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ZNF566 Gene

Orthologs for ZNF566 Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for ZNF566 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF566 35
  • 99.2 (n)
  • 99.28 (a)
ZNF566 36
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia ZNF566 35
  • 91.31 (n)
  • 89.23 (a)
ZNF566 36
  • 89 (a)
OneToOne
dog
(Canis familiaris)
Mammalia ZNF566 36
  • 91 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Zfp566 35
  • 81.69 (n)
  • 80.31 (a)
Zfp566 16
Zfp566 36
  • 80 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 40 (a)
ManyToMany
rat
(Rattus norvegicus)
Mammalia LOC100910651 35
  • 80.57 (n)
  • 79.53 (a)
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes ZAP1 36
  • 12 (a)
OneToMany
Species with no ortholog for ZNF566:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF566 Gene

ENSEMBL:
Gene Tree for ZNF566 (if available)
TreeFam:
Gene Tree for ZNF566 (if available)

Paralogs for ZNF566 Gene

Paralogs for ZNF566 Gene

Selected SIMAP similar genes for ZNF566 Gene using alignment to 5 proteins:

Pseudogenes.org Pseudogenes for ZNF566 Gene

genes like me logo Genes that share paralogs with ZNF566: view

Variants for ZNF566 Gene

Sequence variations from dbSNP and Humsavar for ZNF566 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type MAF
rs1878927 -- 36,450,499(+) tctag(C/T)ggggc intron-variant
rs2052729 -- 36,483,174(+) agata(C/G)ttcat intron-variant
rs2052730 -- 36,483,181(+) TCATA(G/T)TTCTT intron-variant
rs2114288 -- 36,469,915(+) ACTGC(A/T)CTAAA intron-variant
rs2114289 -- 36,477,239(+) tctcc(C/T)gacct intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF566 Gene

Variant ID Type Subtype PubMed ID
nsv833816 CNV Gain 17160897
nsv911648 CNV Loss 21882294
esv2675393 CNV Deletion 23128226
nsv833817 CNV Loss 17160897

Relevant External Links for ZNF566 Gene

HapMap Linkage Disequilibrium report
ZNF566

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF566 Gene

Disorders for ZNF566 Gene

No disorders were found for ZNF566 Gene.

No data available for UniProtKB/Swiss-Prot for ZNF566 Gene

Publications for ZNF566 Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  4. Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions. (PMID: 15342556) Suzuki Y. … Sugano S. (Genome Res. 2004) 3
  5. Systematic analysis of human protein complexes identifies chromosome segregation proteins. (PMID: 20360068) Hutchins J.R. … Peters J.M. (Science 2010) 3

Products for ZNF566 Gene

Sources for ZNF566 Gene

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