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Aliases for ZNF565 Gene

Aliases for ZNF565 Gene

  • Zinc Finger Protein 565 2 3 5

External Ids for ZNF565 Gene

Previous GeneCards Identifiers for ZNF565 Gene

  • GC19M041366
  • GC19M041360
  • GC19M036673
  • GC19M033177
  • GC19M036371
  • GC19M036703
  • GC19M036889
  • GC19M036906

Summaries for ZNF565 Gene

GeneCards Summary for ZNF565 Gene

ZNF565 (Zinc Finger Protein 565) is a Protein Coding gene. Among its related pathways are Gene Expression. GO annotations related to this gene include nucleic acid binding and transcription factor activity, sequence-specific DNA binding. An important paralog of this gene is ZFP14.

UniProtKB/Swiss-Prot for ZNF565 Gene

  • May be involved in transcriptional regulation.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF565 Gene

Genomics for ZNF565 Gene

Regulatory Elements for ZNF565 Gene

Enhancers for ZNF565 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH19F036213 1.2 ENCODE 22.2 +30.9 30948 3.3 HDGF PKNOX1 CREB3L1 MLX WRNIP1 ARID4B SIN3A YBX1 DMAP1 ZNF2 ZNF345 ZNF850 TMEM147-AS1 ZNF567 KMT2B HAUS5 RBM42 LINC00665 ZNF146 ZNF565
GH19F036224 0.9 Ensembl ENCODE 22.7 +21.0 20950 2.2 ZNF362 ZNF211 JUN ZNF670 ATF2 ZNF239 KLF9 FOS ZNF280C ZNF565 LINC00665 ZNF585B TMEM147-AS1 ZNF790 ZNF529-AS1 ZNF585A ZNF568 ZNF790-AS1 ZNF420
GH19F035710 1.7 FANTOM5 Ensembl ENCODE 10.8 +531.1 531065 10.0 HDGF PKNOX1 CREB3L1 WRNIP1 ZFP64 ARID4B SIN3A DMAP1 ZNF2 YY1 U2AF1L4 KMT2B ZNF792 RBM42 TMEM147-AS1 COX6B1 ENSG00000267049 LOC101927572 HAUS5 ENSG00000269086
GH19F035701 1.7 FANTOM5 Ensembl ENCODE 10.8 +543.7 543657 1.6 HDGF PKNOX1 ARID4B SIN3A FEZF1 ZNF2 ZNF416 ZNF143 ZNF548 FOS ZNF567 TMEM147-AS1 U2AF1L4 HAUS5 ZNF792 KMT2B RBM42 COX6B1 ZNF146 LRFN3
GH19F035897 1.6 FANTOM5 ENCODE 10.8 +342.2 342200 13.0 HDGF PKNOX1 CREB3L1 WRNIP1 ARID4B SIN3A FEZF1 ZNF2 YY1 ZNF302 TMEM147-AS1 ZNF345 ZNF850 KMT2B ZNF792 RBM42 ENSG00000267049 ZNF790-AS1 ZNF529-AS1 ZNF790
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around ZNF565 on UCSC Golden Path with GeneCards custom track

Promoters for ZNF565 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00001817328 856 800 CTCF POLR2A MAX ZNF600 RAD21 ETS1

Genomic Location for ZNF565 Gene

Chromosome:
19
Start:
36,182,060 bp from pter
End:
36,246,257 bp from pter
Size:
64,198 bases
Orientation:
Minus strand

Genomic View for ZNF565 Gene

Genes around ZNF565 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF565 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF565 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF565 Gene

Proteins for ZNF565 Gene

  • Protein details for ZNF565 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8N9K5-ZN565_HUMAN
    Recommended name:
    Zinc finger protein 565
    Protein Accession:
    Q8N9K5
    Secondary Accessions:
    • B3KQ35
    • Q6NUS2

    Protein attributes for ZNF565 Gene

    Size:
    539 amino acids
    Molecular mass:
    62445 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ZNF565 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZNF565 Gene

Post-translational modifications for ZNF565 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for ZNF565 Gene

Domains & Families for ZNF565 Gene

Gene Families for ZNF565 Gene

Protein Domains for ZNF565 Gene

Suggested Antigen Peptide Sequences for ZNF565 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q8N9K5

UniProtKB/Swiss-Prot:

ZN565_HUMAN :
  • Contains 1 KRAB domain.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 12 C2H2-type zinc fingers.
Domain:
  • Contains 1 KRAB domain.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 12 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF565: view

Function for ZNF565 Gene

Molecular function for ZNF565 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Gene Ontology (GO) - Molecular Function for ZNF565 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding IEA --
GO:0003677 DNA binding IEA --
GO:0003700 transcription factor activity, sequence-specific DNA binding IBA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF565: view
genes like me logo Genes that share phenotypes with ZNF565: view

Animal Models for ZNF565 Gene

MGI Knock Outs for ZNF565:

Animal Model Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for ZNF565 Gene

Localization for ZNF565 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF565 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZNF565 gene
Compartment Confidence
nucleus 5
cytosol 2

Gene Ontology (GO) - Cellular Components for ZNF565 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular IEA --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF565: view

Pathways & Interactions for ZNF565 Gene

SuperPathways for ZNF565 Gene

SuperPathway Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF565: view

Pathways by source for ZNF565 Gene

2 Reactome pathways for ZNF565 Gene

Interacting Proteins for ZNF565 Gene

Gene Ontology (GO) - Biological Process for ZNF565 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IBA --
GO:0010646 regulation of cell communication IEA --
GO:0022007 convergent extension involved in neural plate elongation IEA --
GO:0060028 convergent extension involved in axis elongation IEA --
genes like me logo Genes that share ontologies with ZNF565: view

No data available for SIGNOR curated interactions for ZNF565 Gene

Transcripts for ZNF565 Gene

Unigene Clusters for ZNF565 Gene

Zinc finger protein 565:
Representative Sequences:

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF565 Gene

ExUns: 1 ^ 2a · 2b ^ 3 ^ 4 ^ 5a · 5b ^ 6 ^ 7a · 7b · 7c · 7d · 7e
SP1: - - - -
SP2: - -
SP3: -
SP4: - - -
SP5: - -
SP6:

Relevant External Links for ZNF565 Gene

GeneLoc Exon Structure for
ZNF565
ECgene alternative splicing isoforms for
ZNF565

Expression for ZNF565 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for ZNF565 Gene

NURSA nuclear receptor signaling pathways regulating expression of ZNF565 Gene:

ZNF565

SOURCE GeneReport for Unigene cluster for ZNF565 Gene:

Hs.596338
genes like me logo Genes that share expression patterns with ZNF565: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for ZNF565 Gene

Orthologs for ZNF565 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF565 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF565 34 35
  • 99.8 (n)
dog
(Canis familiaris)
Mammalia ZNF565 34
  • 89.89 (n)
cow
(Bos Taurus)
Mammalia ZNF565 34 35
  • 88.35 (n)
mouse
(Mus musculus)
Mammalia Zfp84 34 16
  • 62.31 (n)
rat
(Rattus norvegicus)
Mammalia Zfp84 34
  • 61.34 (n)
Species where no ortholog for ZNF565 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF565 Gene

ENSEMBL:
Gene Tree for ZNF565 (if available)
TreeFam:
Gene Tree for ZNF565 (if available)

Paralogs for ZNF565 Gene

(552) SIMAP similar genes for ZNF565 Gene using alignment to 4 proteins:

genes like me logo Genes that share paralogs with ZNF565: view

Variants for ZNF565 Gene

Sequence variations from dbSNP and Humsavar for ZNF565 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
rs10405434 -- 36,216,776(+) GACTG(A/T)GAAAG intron-variant, upstream-variant-2KB
rs10409091 -- 36,201,380(+) TTCAT(C/G)TTTGG intron-variant
rs10411031 -- 36,201,221(+) tgctt(A/G)agccc intron-variant
rs10411418 -- 36,187,378(+) ttttt(C/T)tgaga intron-variant
rs10412772 -- 36,205,540(+) aaaaa(A/G)aaaga intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for ZNF565 Gene

Variant ID Type Subtype PubMed ID
nsv579425 CNV loss 21841781
nsv509739 CNV insertion 20534489
esv1010122 CNV insertion 20482838

Variation tolerance for ZNF565 Gene

Residual Variation Intolerance Score: 25.8% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.16; 39.17% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ZNF565 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ZNF565

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF565 Gene

Disorders for ZNF565 Gene

Relevant External Links for ZNF565

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ZNF565

No disorders were found for ZNF565 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF565 Gene

Publications for ZNF565 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 64
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 64
  3. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3 64
  4. The DNA sequence and biology of human chromosome 19. (PMID: 15057824) Grimwood J. … Lucas S.M. (Nature 2004) 4 64
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3 64

Products for ZNF565 Gene

Sources for ZNF565 Gene

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