ZNF565 Gene
protein-coding GIFtS: 46
GCID: GC19M036673
|
|
zinc finger protein 565
| |
Aliases
for ZNF565 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Zinc Finger Protein 5651 2 | | FLJ369911 |
Export aliases for ZNF565 gene to outside databasesPrevious GC identifers: GC19M041366 GC19M041360 GC19M033177 |
Summaries
for ZNF565 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
UniProtKB/Swiss-Prot: ZN565_HUMAN, Q8N9K5Function: May be involved in transcriptional regulation
|
Genomic Views
for ZNF565 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000019.9 NC_018930.1 NT_011109.16
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the ZNF565 gene promoter:
USF1 USF-1 USF2 USF-1:USF-2 HNF-4alpha1
Other transcription factors
Search SABiosciences Chromatin IP Primers for ZNF565
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZNF565 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 19q13.12 Ensembl cytogenetic band: 19q13.12 HGNC chromosome: 19ZNF565 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 19 GeneLoc Exon Structure GeneLoc location for GC19M036673: view genomic region
(about GC identifiers)
Start:
|
36,673,187 bp from pter |
End:
|
36,737,159 bp from pter |
Size:
|
63,973 bases |
Orientation:
|
minus strand |
|
Proteins
for ZNF565 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: ZN565_HUMAN, Q8N9K5 (See
protein sequence)Recommended Name: Zinc finger protein 565 Size: 499 amino acids; 57827 Da
Subcellular location: Nucleus (Potential)
Secondary accessions: Q6NUS2Explore the universe of human proteins at neXtProt for ZNF565: NX_Q8N9K5
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q8N9K5
ZNF565 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_001035939.1 NP_689690.3
ENSEMBL proteins: ENSP00000376013 ENSP00000347234 ENSP00000465906 ENSP00000468673 ENSP00000306869 Reactome Protein details: Q8N9K5
Human Recombinant Protein Products for ZNF565:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005634 | nucleus |
IEA | -- |
ZNF565 for ontologies About GeneDecksing
ZNF565 Antibody Products:
Assay Products for ZNF565: |
Protein
Domains /
Families
for ZNF565 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ZNF565 for domains About GeneDecksing
4 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q8N9K5ProtoNet protein and cluster: Q8N9K5 1 Blocks protein family: IPB001909 KRAB box
UniProtKB/Swiss-Prot: ZN565_HUMAN, Q8N9K5Similarity: Belongs to the krueppel C2H2-type zinc-finger protein familySimilarity: Contains 12 C2H2-type zinc fingersSimilarity: Contains 1 KRAB domain |
Function
for ZNF565 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Molecular Function:
UniProtKB/Swiss-Prot Summary: ZN565_HUMAN, Q8N9K5Function: May be involved in transcriptional regulation Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table
ZNF565 for ontologies About GeneDecksing
Phenotypes:
1 GenomeRNAi human phenotype for ZNF565:
Animal Models:
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF565 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF565 (see all 2)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 2): ZNF565 (NM_152477) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ZNF565 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF565 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF565 |
|
Pathways & Interactions
for ZNF565 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Generic Transcription Pathway | |
Pathway sources
See GeneCards unified pathways
Show all pathways
2 
Reactome Pathways for ZNF565
ZNF565 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ZNF565
Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006351 | transcription, DNA-dependent |
IEA | -- | | GO:0006355 | regulation of transcription, DNA-dependent |
IEA | -- |
ZNF565 for ontologies About GeneDecksing
|
Drugs & Compounds
for ZNF565 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for ZNF565
Search CenterWatch for drugs/clinical trials and news about ZNF565 / ZN565
|
Transcripts
for ZNF565 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for ZNF565 gene (2 alternative transcripts): NM_001042474.1 NM_152477.3 Unigene Cluster for ZNF565: Zinc finger protein 565 Hs.596338 [show with all ESTs]Unigene Representative Sequence: AK0572907 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000392173(uc002odo.3) ENST00000355114 ENST00000591473 ENST00000585994
ENST00000587803 ENST00000586648 ENST00000304116(uc002odn.3 uc010ees.3 uc002odp.1)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF565 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF565 (see all 2)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 2): ZNF565 (NM_152477) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ZNF565 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF565 |
Additional cDNA sequence: AK057290.1 AK094310.1 AK308212.1 2 DOTS entries: DT.100020997 DT.210816 24/45 AceView cDNA sequences (see all 45): CA306561 AK094310 AA476586 CA396857 CD251687 AA448909 AA973170 BG432401 BF064261 CB960081 AK057290 AA353953 AI022739 AI680830 CK819275 AW051368 BC068453 CB959667 BI827546 BE466825 H65544 AW957690 NM_152477 AI032079
GeneLoc Exon Structure
5/6 Alternative Splicing Database (ASD) splice patterns (SP) for ZNF565 (see all 6) About this scheme
| ExUns: | 1 | ^ | 2a | · | 2b | ^ | 3 | ^ | 4 | ^ | 5a | · | 5b | ^ | 6 | ^ | 7a | · | 7b | · | 7c | · | 7d | · | 7e |
|---|
|
| SP1: | | | - | | - | | - | | | | | | - | | | | | | | | | | | | | | |
| SP2: | | | | | | | - | | | | | | - | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | - | | | | | | | | | | | | | | |
| SP4: | | | | | | | - | | - | | | | - | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | - | | | | - | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for ZNF565
|
Expression
for ZNF565 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ZNF565 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: AATGTGGGAA
About this image
See ZNF565 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for ZNF565
SOURCE GeneReport for Unigene cluster: Hs.596338
SABiosciences Custom PCR Arrays for ZNF565
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZNF565
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat ZNF565 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZNF565 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZNF565 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF565 |
Orthologs
for ZNF565 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for ZNF565 gene from 1/7 species (see all 7) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
honey bee
(Apis mellifera) |
Insecta |
-- |
-- |
20(a) |
1 → many |
GroupUn.197(18775-21878) |
ENSEMBL Gene Tree for ZNF565 (if available)
TreeFam Gene Tree for ZNF565 (if available) |
Paralogs
for ZNF565 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for ZNF565 gene
- ZNF4202 ZNF5292 ZFP302 ZNF1402 ZNF780A2 ZNF3832 ZNF7902 ZNF5822
- ZFP822 ZNF302 ZNF5732 ZNF5402 ZNF5712 ZNF3312 ZFP142 ZNF4612
- ZNF2832 ZNF4042 ZNF6072 ZNF8292 ZNF5662 ENSG000002675522
18/550 SIMAP similar genes for ZNF565 using alignment to 4 protein entries: ZN565_HUMAN (see all proteins)
(see all similar genes):ZNF818P MGC12518 ZNF738 ZNF78L1 ZNF721 ZNF66
kr-znf3 KRBOX4 ZNF267 ZNF93 ZNF283 ZNF726
ZFP3 ZNF397 ZNF484 ZNF616 ZNF623 ZNF140
ZNF565 for paralogs About GeneDecksing
1 Pseudogenes.org Pseudogene for ZNF565
PGOHUM00000260464
|
Genomic Variants
for ZNF565 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 19 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for ZNF565 (36673187 - 36737159 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for ZNF565: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ZNF565 |
|
Disorders
/ Diseases
for ZNF565 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
 ZNF565 for disorders About MalaCards
ZNF565 for disorders About GeneDecksing
OMIM gene information: 614275
OMIM disorders: --
Export disorders for ZNF565 gene to outside databases
|
Publications
for ZNF565 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ZNF565 gene integrated from 9 sources:
(articles sorted by number of sources associating them with ZNF565) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
|
External Searches for ZNF565 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing ZNF565 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing ZNF565 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing ZNF565 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for ZNF565 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for ZNF565 gene:
Search GeneIP for patents involving ZNF565
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for ZNF565 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for ZNF565 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ZNF565 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZNF565 | | | OriGene Protein Over-expression Lysate for ZNF565 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for ZNF565 | | OriGene 3'-UTR Clone for ZNF565 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF565 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF565 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for ZNF565 | | OriGene Custom Protein Services for ZNF565 | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ZNF565 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ZNF565 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZNF565 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ZNF565 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZNF565 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZNF565 |
| |
 |  |  |  | |
| | | | Search Tocris compounds for ZNF565 |
| |  |  |  |  | | | | |
 |
 |
 |
 | | | ZNF565 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF565 |
|  |  |  |  | | | | Search ThermoFisher Antibodies for ZNF565 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF565 |
| |  | |
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