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Aliases for ZNF563 Gene

Aliases for ZNF563 Gene

  • Zinc Finger Protein 563 2 3

External Ids for ZNF563 Gene

Summaries for ZNF563 Gene

GeneCards Summary for ZNF563 Gene

ZNF563 (Zinc Finger Protein 563) is a Protein Coding gene. Among its related pathways are Gene Expression and Gene Expression. An important paralog of this gene is ZNF709.

UniProtKB/Swiss-Prot for ZNF563 Gene

  • May be involved in transcriptional regulation

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF563 Gene

Genomics for ZNF563 Gene

Genomic Location for ZNF563 Gene

Start:
12,317,477 bp from pter
End:
12,333,720 bp from pter
Size:
16,244 bases
Orientation:
Minus strand

Genomic View for ZNF563 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZNF563 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF563 Gene

No data available for Regulatory Elements for ZNF563 Gene

Proteins for ZNF563 Gene

  • Protein details for ZNF563 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8TA94-ZN563_HUMAN
    Recommended name:
    Zinc finger protein 563
    Protein Accession:
    Q8TA94
    Secondary Accessions:
    • B2R9E7
    • Q8NAT7

    Protein attributes for ZNF563 Gene

    Size:
    476 amino acids
    Molecular mass:
    55434 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ZNF563 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZNF563 Gene

Proteomics data for ZNF563 Gene at MOPED

Post-translational modifications for ZNF563 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF563 Gene

ENSEMBL proteins:
Reactome Protein details:
REFSEQ proteins:

No data available for DME Specific Peptides for ZNF563 Gene

Domains for ZNF563 Gene

Gene Families for ZNF563 Gene

HGNC:
  • ZNF :Zinc fingers, C2H2-type

Protein Domains for ZNF563 Gene

UniProtKB/Swiss-Prot:

ZN563_HUMAN
Domain:
  • Contains 1 KRAB domain.:
    • Q8TA94
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.:
    • Q8TA94
Similarity:
  • Contains 12 C2H2-type zinc fingers.:
    • Q8TA94
genes like me logo Genes that share domains with ZNF563: view

Function for ZNF563 Gene

Molecular function for ZNF563 Gene

UniProtKB/Swiss-Prot Function: May be involved in transcriptional regulation

Gene Ontology (GO) - Molecular Function for ZNF563 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding --
GO:0003677 DNA binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF563: view

miRNA for ZNF563 Gene

miRTarBase miRNAs that target ZNF563

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for ZNF563 Gene

Localization for ZNF563 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF563 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF563 Gene COMPARTMENTS Subcellular localization image for ZNF563 gene
Compartment Confidence
nucleus 3
cytosol 2

Gene Ontology (GO) - Cellular Components for ZNF563 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF563: view

Pathways for ZNF563 Gene

SuperPathways for ZNF563 Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF563: view

Pathways by source for ZNF563 Gene

2 Reactome pathways for ZNF563 Gene

Interacting Proteins for ZNF563 Gene

Gene Ontology (GO) - Biological Process for ZNF563 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF563: view

Transcripts for ZNF563 Gene

mRNA/cDNA for ZNF563 Gene

Unigene Clusters for ZNF563 Gene

Zinc finger protein 563:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF563 Gene

ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5a · 5b ^ 6a · 6b
SP1: -
SP2:
SP3: -

Relevant External Links for ZNF563 Gene

GeneLoc Exon Structure for
ZNF563
ECgene alternative splicing isoforms for
ZNF563

Expression for ZNF563 Gene

mRNA expression in normal human tissues for ZNF563 Gene

mRNA differential expression in normal tissues according to GTEx for ZNF563 Gene

This gene is overexpressed in Testis (5.7).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for ZNF563 Gene

SOURCE GeneReport for Unigene cluster for ZNF563 Gene Hs.663510

genes like me logo Genes that share expressions with ZNF563: view

Orthologs for ZNF563 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF563 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF563 36
  • 99.72 (n)
  • 99.58 (a)
ZNF563 37
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia -- 37
  • 47 (a)
ManyToMany
mouse
(Mus musculus)
Mammalia Zfp563 36
  • 64.34 (n)
  • 50.23 (a)
Zfp563 16
rat
(Rattus norvegicus)
Mammalia Zfp563 36
  • 64.19 (n)
  • 50.45 (a)
Species with no ortholog for ZNF563:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF563 Gene

ENSEMBL:
Gene Tree for ZNF563 (if available)
TreeFam:
Gene Tree for ZNF563 (if available)

Paralogs for ZNF563 Gene

Selected SIMAP similar genes for ZNF563 Gene using alignment to 3 proteins:

genes like me logo Genes that share paralogs with ZNF563: view

Variants for ZNF563 Gene

Sequence variations from dbSNP and Humsavar for ZNF563 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type MAF
rs1592998 -- 12,329,276(-) caagc(A/T)ggtct intron-variant
rs1592999 -- 12,329,274(-) agcag(A/G)tctcg intron-variant
rs1593000 -- 12,329,054(-) ttaga(A/G)tttta intron-variant
rs1862507 -- 12,325,760(-) ctttg(C/T)ggatg intron-variant
rs2194175 -- 12,333,782(-) actca(G/T)tgccc upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for ZNF563 Gene

Variant ID Type Subtype PubMed ID
nsv911068 CNV Gain 21882294
nsv911069 CNV Loss 21882294
nsv911070 CNV Gain 21882294
esv2718192 CNV Deletion 23290073
nsv911071 CNV Gain 21882294

Relevant External Links for ZNF563 Gene

HapMap Linkage Disequilibrium report
ZNF563

Disorders for ZNF563 Gene

No disorders were found for ZNF563 Gene.

No data available for UniProtKB/Swiss-Prot for ZNF563 Gene

Publications for ZNF563 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  3. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  4. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PMID: 17207965) Lamesch P. … Vidal M. (Genomics 2007) 3
  5. Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition. (PMID: 22505724) Udeshi N.D. … Carr S.A. (Mol. Cell Proteomics 2012) 3

Products for ZNF563 Gene

Sources for ZNF563 Gene

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