ZNF563 Gene
protein-coding GIFtS: 44
GCID: GC19M012429
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zinc finger protein 563
| |
Aliases
for ZNF563 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Zinc Finger Protein 5631 2 | | FLJ347971 |
Export aliases for ZNF563 gene to outside databasesPrevious GC identifers: GC19M012291 GC19M012292 GC19M012004 |
Summaries
for ZNF563 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
UniProtKB/Swiss-Prot: ZN563_HUMAN, Q8TA94Function: May be involved in transcriptional regulation
|
Genomic Views
for ZNF563 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000019.9 NC_018930.1 NT_011295.11
Regulatory elements:
 Search SABiosciences Regulatory transcription factor binding sites for ZNF563
Other transcription factors
Search SABiosciences Chromatin IP Primers for ZNF563
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZNF563 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 19p13.2 Ensembl cytogenetic band: 19p13.2 HGNC chromosome: 19ZNF563 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 19 GeneLoc Exon Structure GeneLoc location for GC19M012429: view genomic region
(about GC identifiers)
Start:
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12,428,291 bp from pter |
End:
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12,444,534 bp from pter |
Size:
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16,244 bases |
Orientation:
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minus strand |
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Proteins
for ZNF563 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: ZN563_HUMAN, Q8TA94 (See
protein sequence)Recommended Name: Zinc finger protein 563 Size: 476 amino acids; 55434 Da
Subcellular location: Nucleus (Potential)
Secondary accessions: B2R9E7 Q8NAT7Alternative splicing: 2 isoforms: Q8TA94-1 Q8TA94-2 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for ZNF563: NX_Q8TA94
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q8TA94
ZNF563 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_660319.1
ENSEMBL proteins: ENSP00000293725 Reactome Protein details: Q8TA94
Human Recombinant Protein Products for ZNF563:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005634 | nucleus |
IEA | -- |
ZNF563 for ontologies About GeneDecksing
ZNF563 Antibody Products:
Assay Products for ZNF563: |
Protein
Domains /
Families
for ZNF563 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ZNF563 for domains About GeneDecksing
4 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q8TA94ProtoNet protein and cluster: Q8TA94 1 Blocks protein family: IPB001909 KRAB box
UniProtKB/Swiss-Prot: ZN563_HUMAN, Q8TA94Similarity: Belongs to the krueppel C2H2-type zinc-finger protein familySimilarity: Contains 12 C2H2-type zinc fingersSimilarity: Contains 1 KRAB domain |
Function
for ZNF563 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Molecular Function:
UniProtKB/Swiss-Prot Summary: ZN563_HUMAN, Q8TA94Function: May be involved in transcriptional regulation Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table
ZNF563 for ontologies About GeneDecksing
Animal Models:
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF563 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF563
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: ZNF563 (NM_145276) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ZNF563 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF563 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF563 |
|
Pathways & Interactions
for ZNF563 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Generic Transcription Pathway | |
Pathway sources
See GeneCards unified pathways
Show all pathways
2 
Reactome Pathways for ZNF563
ZNF563 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ZNF563
Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006351 | transcription, DNA-dependent |
IEA | -- | | GO:0006355 | regulation of transcription, DNA-dependent |
IEA | -- |
ZNF563 for ontologies About GeneDecksing
|
Drugs & Compounds
for ZNF563 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for ZNF563
Search CenterWatch for drugs/clinical trials and news about ZNF563 / ZN563
|
Transcripts
for ZNF563 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for ZNF563 gene: NM_145276.2 Unigene Cluster for ZNF563: Zinc finger protein 563 Hs.663510 [show with all ESTs]Unigene Representative Sequence: NM_1452761 Ensembl transcript including schematic representation, and UCSC links where relevant: ENST00000293725(uc002mtp.3 uc002mtq.2)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF563 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF563
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: ZNF563 (NM_145276) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ZNF563 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF563 |
Additional cDNA sequence: AK092116.1 AK313755.1 BC022523.1 5 DOTS entries: DT.70103203 DT.100010845 DT.91697593 DT.121488331 DT.97786887 14 AceView cDNA sequences: AW239538 AA535963 AW450494 AW239273 AK092116 AL042822 AX747362 AA730339 BG706839 AI635114 AL042823 BF980369 AW069493 BE766909
GeneLoc Exon Structure
3 Alternative Splicing Database (ASD) splice patterns (SP) for ZNF563 About this scheme
| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5a | · | 5b | ^ | 6a | · | 6b |
|---|
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| SP1: | | | | | - | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | - | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for ZNF563
|
Expression
for ZNF563 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ZNF563 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CCAAGTCCTT
About this image
See ZNF563 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for ZNF563
SOURCE GeneReport for Unigene cluster: Hs.663510
SABiosciences Custom PCR Arrays for ZNF563
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZNF563
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat ZNF563 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZNF563 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZNF563 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF563 |
Orthologs
for ZNF563 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
--
ENSEMBL Gene Tree for ZNF563 (if available)
TreeFam Gene Tree for ZNF563 (if available) |
Paralogs
for ZNF563 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for ZNF563 gene
- ZNF6692 ZNF4902 ZNF5642 ZNF4412 ZNF8782 ENSG000002671792 ZNF142 ENSG000001968262
- ZNF7002 ZNF692 ZNF4402 ZNF4432 ZNF442 ZNF4392 ZNF8232 ZNF4912
- ENSG000001884742 ZNF5552 ZNF7092 ZNF6252 ZNF7992 ZNF202 ZNF1012 ZNF7912
- ZNF4422 ZNF4332 ZNF572 ZNF6272 ENSG000002573552 ZNF1362 ZNF5562 ZNF6702
- ZNF7632 ZNF1242 ZNF6992 ZNF8442 ZNF772
18/443 SIMAP similar genes for ZNF563 using alignment to 3 protein entries: ZN563_HUMAN (see all proteins)
(see all similar genes):ZNF799 ZNF823 DKFZp666C237 HZF36 ZNF443 ZNF442
ZNF44 ZNF627 ZNF397 ZNF491 ZNF763 ZNF833P
zf30 ZNF844 ZNF14 ZNF136 DKFZp666M039 ZFS-1
ZNF563 for paralogs About GeneDecksing
|
Genomic Variants
for ZNF563 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 19 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for ZNF563 (12428291 - 12444534 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for ZNF563: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ZNF563 |
|
Disorders
/ Diseases
for ZNF563 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications
for ZNF563 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ZNF563 gene integrated from 9 sources:
(articles sorted by number of sources associating them with ZNF563) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)
- hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PubMed id 17207965)1 Lamesch P.... Vidal M. (2007)
- Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
|
External Searches for ZNF563 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing ZNF563 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing ZNF563 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing ZNF563 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for ZNF563 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for ZNF563 gene:
Search GeneIP for patents involving ZNF563
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for ZNF563 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for ZNF563 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ZNF563 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZNF563 | | | OriGene Protein Over-expression Lysate for ZNF563 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for ZNF563 | | OriGene 3'-UTR Clone for ZNF563 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF563 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF563 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ZNF563 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ZNF563 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZNF563 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ZNF563 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZNF563 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZNF563 |
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 |  |  |  | |
| | | | Search Tocris compounds for ZNF563 |
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 | | | ZNF563 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF563 |
|  |  |  |  | | | | Search ThermoFisher Antibodies for ZNF563 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF563 |
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