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Aliases for ZNF562 Gene

Aliases for ZNF562 Gene

  • Zinc Finger Protein 562 2 3 5

External Ids for ZNF562 Gene

Previous GeneCards Identifiers for ZNF562 Gene

  • GC19M009621
  • GC19M009759
  • GC19M009340

Summaries for ZNF562 Gene

GeneCards Summary for ZNF562 Gene

ZNF562 (Zinc Finger Protein 562) is a Protein Coding gene. Among its related pathways are Gene Expression. GO annotations related to this gene include nucleic acid binding. An important paralog of this gene is ZNF561.

UniProtKB/Swiss-Prot for ZNF562 Gene

  • May be involved in transcriptional regulation.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF562 Gene

Genomics for ZNF562 Gene

Regulatory Elements for ZNF562 Gene

Enhancers for ZNF562 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH19F010100 1.5 FANTOM5 ENCODE 40.5 -429.1 -429086 8.3 HDGF PKNOX1 CREB3L1 MLX WRNIP1 ZFP64 ARID4B SIN3A YBX1 DMAP1 FBXL12 ZNF699 ZNF561 LOC100419831 ZNF559 TIMM29 YIPF2 ZNF562 EIF3G ZNF121
GH19F010379 1.1 ENCODE 27.7 -705.2 -705225 1.9 HDGF PKNOX1 CREB3L1 WRNIP1 ZFP64 ARID4B SIN3A DMAP1 ZNF2 YY1 FBXL12 ZNF561 LOC100419831 RAVER1 TIMM29 ZNF426 YIPF2 ZNF121 ZNF562 EIF3G
GH19F010267 1.2 ENCODE 19.3 -595.0 -595036 5.6 MLX CREB3L1 ZFP64 DMAP1 YY1 SLC30A9 ZNF416 ZNF143 ZNF263 SP3 ZNF699 FBXL12 ZNF559 LOC100419831 ZNF561 ZNF426 RAVER1 TIMM29 EIF3G ZNF121
GH19F010423 1.9 FANTOM5 Ensembl ENCODE 10.2 -753.3 -753316 10.4 HDGF PKNOX1 ARNT WRNIP1 ARID4B SIN3A YBX1 ZNF2 YY1 ZNF143 ZNF561 EIF3G FBXL12 ZNF121 PDE4A C19orf38 RAVER1 ICAM1 TIMM29 LOC100419831
GH19F010005 1.4 FANTOM5 ENCODE 10.9 -333.0 -333011 4.8 HDGF PKNOX1 ARNT CREB3L1 ARID4B SIN3A DMAP1 FEZF1 ZNF2 YY1 COL5A3 FBXL12 LOC100419831 ZNF559 ZNF561 ZNF699 ZNF121 LOC100418883 OR7E24 OR7D1P
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around ZNF562 on UCSC Golden Path with GeneCards custom track

Promoters for ZNF562 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000214786 601 2199 HDGF PKNOX1 ARNT CREB3L1 ARID4B SIN3A DMAP1 YY1 CBX5 ZNF143

Genomic Location for ZNF562 Gene

Chromosome:
19
Start:
9,641,808 bp from pter
End:
9,675,302 bp from pter
Size:
33,495 bases
Orientation:
Minus strand

Genomic View for ZNF562 Gene

Genes around ZNF562 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF562 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF562 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF562 Gene

Proteins for ZNF562 Gene

  • Protein details for ZNF562 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6V9R5-ZN562_HUMAN
    Recommended name:
    Zinc finger protein 562
    Protein Accession:
    Q6V9R5
    Secondary Accessions:
    • Q32MN2
    • Q9NXS5

    Protein attributes for ZNF562 Gene

    Size:
    426 amino acids
    Molecular mass:
    48563 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ZNF562 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZNF562 Gene

Post-translational modifications for ZNF562 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for ZNF562 Gene

Domains & Families for ZNF562 Gene

Gene Families for ZNF562 Gene

Graphical View of Domain Structure for InterPro Entry

Q6V9R5

UniProtKB/Swiss-Prot:

ZN562_HUMAN :
  • Contains 1 KRAB domain.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 8 C2H2-type zinc fingers.
Domain:
  • Contains 1 KRAB domain.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 8 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF562: view

Function for ZNF562 Gene

Molecular function for ZNF562 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Gene Ontology (GO) - Molecular Function for ZNF562 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding IBA --
GO:0003676 nucleic acid binding IEA --
GO:0003677 DNA binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF562: view

Phenotypes for ZNF562 Gene

genes like me logo Genes that share phenotypes with ZNF562: view

Animal Model Products

miRNA for ZNF562 Gene

miRTarBase miRNAs that target ZNF562

Inhibitory RNA Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF562 Gene

Localization for ZNF562 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF562 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZNF562 gene
Compartment Confidence
nucleus 5
cytosol 2

Gene Ontology (GO) - Cellular Components for ZNF562 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular IEA --
GO:0005634 nucleus IEA,IBA --
genes like me logo Genes that share ontologies with ZNF562: view

Pathways & Interactions for ZNF562 Gene

SuperPathways for ZNF562 Gene

SuperPathway Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF562: view

Pathways by source for ZNF562 Gene

2 Reactome pathways for ZNF562 Gene

Gene Ontology (GO) - Biological Process for ZNF562 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA,IBA --
genes like me logo Genes that share ontologies with ZNF562: view

No data available for SIGNOR curated interactions for ZNF562 Gene

Transcripts for ZNF562 Gene

Unigene Clusters for ZNF562 Gene

Zinc finger protein 562:
Representative Sequences:

Inhibitory RNA Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF562 Gene

ExUns: 1a · 1b ^ 2 ^ 3 ^ 4a · 4b ^ 5a · 5b ^ 6a · 6b · 6c · 6d
SP1: -
SP2: -
SP3: - - -
SP4: - -
SP5:
SP6: - - -

Relevant External Links for ZNF562 Gene

GeneLoc Exon Structure for
ZNF562
ECgene alternative splicing isoforms for
ZNF562

Expression for ZNF562 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for ZNF562 Gene

NURSA nuclear receptor signaling pathways regulating expression of ZNF562 Gene:

ZNF562

SOURCE GeneReport for Unigene cluster for ZNF562 Gene:

Hs.371107
genes like me logo Genes that share expression patterns with ZNF562: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for ZNF562 Gene

Orthologs for ZNF562 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF562 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF562 35
  • 99 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Zfp266 35
  • 41 (a)
OneToMany
dog
(Canis familiaris)
Mammalia -- 35
  • 35 (a)
OneToMany
cow
(Bos Taurus)
Mammalia -- 35
  • 23 (a)
OneToMany
Species where no ortholog for ZNF562 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF562 Gene

ENSEMBL:
Gene Tree for ZNF562 (if available)
TreeFam:
Gene Tree for ZNF562 (if available)

Paralogs for ZNF562 Gene

Paralogs for ZNF562 Gene

(500) SIMAP similar genes for ZNF562 Gene using alignment to 9 proteins:

Pseudogenes.org Pseudogenes for ZNF562 Gene

genes like me logo Genes that share paralogs with ZNF562: view

Variants for ZNF562 Gene

Sequence variations from dbSNP and Humsavar for ZNF562 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
rs10401755 -- 9,672,034(+) ATAAA(A/G)GAATA intron-variant
rs10404587 -- 9,675,801(+) aaata(G/T)ctggg upstream-variant-2KB
rs10404643 -- 9,672,297(+) TTTTT(A/T)ATTTA intron-variant
rs10405425 -- 9,660,455(+) aaccc(A/G)tctcc intron-variant
rs10405461 -- 9,659,795(+) GAATT(C/T)TAAAA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF562 Gene

Variant ID Type Subtype PubMed ID
nsv963003 CNV duplication 23825009
nsv1060112 CNV gain 25217958
esv3643640 CNV loss 21293372
esv3643639 CNV loss 21293372
esv2718156 CNV deletion 23290073
esv2661640 CNV deletion 23128226

Variation tolerance for ZNF562 Gene

Residual Variation Intolerance Score: 74.3% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.58; 30.53% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ZNF562 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ZNF562

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF562 Gene

Disorders for ZNF562 Gene

Relevant External Links for ZNF562

Genetic Association Database (GAD)
ZNF562
Human Genome Epidemiology (HuGE) Navigator
ZNF562
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ZNF562

No disorders were found for ZNF562 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF562 Gene

Publications for ZNF562 Gene

  1. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3 46 64
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 64
  3. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3 64
  4. Ubiquitin-mediated proteolysis of HuR by heat shock. (PMID: 19322201) Abdelmohsen K. … Gorospe M. (EMBO J. 2009) 3 64
  5. Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions. (PMID: 15342556) Suzuki Y. … Sugano S. (Genome Res. 2004) 3 64

Products for ZNF562 Gene

Sources for ZNF562 Gene

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