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ZNF562 Gene

protein-coding   GIFtS: 48
GCID: GC19M009759

Zinc Finger Protein 562

  Search for ZNF562
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Zinc Finger Protein 5621 2

External Ids:    HGNC: 259501   Entrez Gene: 548112   Ensembl: ENSG000001714667   UniProtKB: Q6V9R53   

Export aliases for ZNF562 gene to outside databases

Previous GC identifers: GC19M009621 GC19M009622 GC19M009340


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for ZNF562 Gene:
ZNF562 (zinc finger protein 562) is a protein-coding gene. An important paralog of this gene is ZNF812.

UniProtKB/Swiss-Prot: ZN562_HUMAN, Q6V9R5
Function: May be involved in transcriptional regulation




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000019.9  NT_011295.12  NC_018930.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the ZNF562 gene promoter:
         Nkx3-1   Max1   Pbx1a   Nkx3-1 v1   LCR-F1   YY1   C/EBPalpha   CHOP-10   FAC1   c-Myc   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidZNF562 promoter sequence
   Search Chromatin IP Primers for ZNF562

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat ZNF562


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 19p13.2   Ensembl cytogenetic band:  19p13.2   HGNC cytogenetic band: 19p13.2

ZNF562 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ZNF562 gene location

GeneLoc information about chromosome 19         GeneLoc Exon Structure

GeneLoc location for GC19M009759:  view genomic region     (about GC identifiers)

Start:
9,759,330 bp from pter      End:
9,785,776 bp from pter
Size:
26,447 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: ZN562_HUMAN, Q6V9R5 (See protein sequence)
Recommended Name: Zinc finger protein 562  
Size: 426 amino acids; 48563 Da
Secondary accessions: Q32MN2 Q9NXS5
Alternative splicing: 2 isoforms:  Q6V9R5-1   Q6V9R5-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for ZNF562: NX_Q6V9R5

Explore proteomics data for ZNF562 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See ZNF562 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (3 alternative transcripts): 
    NP_001123503.1  NP_001123504.1  NP_060126.2  

    ENSEMBL proteins: 
     ENSP00000293648   ENSP00000410734   ENSP00000464716   ENSP00000466728   ENSP00000468039  
     ENSP00000466911   ENSP00000466039   ENSP00000468775   ENSP00000411784   ENSP00000442614  
     ENSP00000440451   ENSP00000445816  
    Reactome Protein details: Q6V9R5

    ZNF562 Human Recombinant Protein Products:

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    Cloud-Clone Corp. Proteins for ZNF562

     
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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    ZNF: Zinc fingers, C2H2-type

    4 InterPro protein domains:
     IPR001909 Krueppel-associated_box
     IPR015880 Znf_C2H2-like
     IPR013087 Znf_C2H2/integrase_DNA-bd
     IPR007087 Znf_C2H2

    Graphical View of Domain Structure for InterPro Entry Q6V9R5

    ProtoNet protein and cluster: Q6V9R5

    2 Blocks protein domains:
    IPB001909 KRAB box
    IPB007086 C2H2-type zinc finger signature


    UniProtKB/Swiss-Prot: ZN562_HUMAN, Q6V9R5
    Similarity: Belongs to the krueppel C2H2-type zinc-finger protein family
    Similarity: Contains 8 C2H2-type zinc fingers
    Similarity: Contains 1 KRAB domain


    Find genes that share domains with ZNF562           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: ZN562_HUMAN, Q6V9R5
    Function: May be involved in transcriptional regulation

         Gene Ontology (GO): 3 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003676nucleic acid binding ----
    GO:0003677DNA binding IEA--
    GO:0046872metal ion binding IEA--
         
    Find genes that share ontologies with ZNF562           About GenesLikeMe


    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for ZNF562
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for ZNF562

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for ZNF562
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for ZNF562

    miRNA
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    miRTarBase miRNAs that target ZNF562:
    hsa-mir-106b-5p (MIRT044315), hsa-mir-181a-5p (MIRT025146)

    Block miRNA regulation of human, mouse, rat ZNF562 using miScript Target Protectors
    8 qRT-PCR Assays for microRNAs that regulate ZNF562:
    hsa-miR-181c hsa-miR-1260b hsa-miR-181a hsa-miR-181d hsa-miR-1260 hsa-miR-188-3p hsa-miR-181b hsa-miR-4262
    SwitchGear 3'UTR luciferase reporter plasmidZNF562 3' UTR sequence
    Inhib. RNA
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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF562


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    ZN562_HUMAN, Q6V9R5: Nucleus (Potential)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus3
    cytosol2

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005622intracellular ----
    GO:0005634nucleus IEA--

    Find genes that share ontologies with ZNF562           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for ZNF562 About    
    See pathways by source

    SuperPathContained pathways About
    1Gene Expression
    Generic Transcription Pathway0.40
    Gene Expression0.40


    Find genes that share SuperPaths with ZNF562           About GenesLikeMe

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    1 Reactome Pathway for ZNF562
        Generic Transcription Pathway


        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for ZNF562
    Interactions:

        Search GeneGlobe Interaction Network for ZNF562

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    1 Interacting protein for ZNF562 (ENSP000004107344) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ELAVL1ENSP000003852694STRING: ENSP00000385269
    About this table

    Gene Ontology (GO): 2 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006351transcription, DNA-templated IEA--
    GO:0006355regulation of transcription, DNA-templated IEA--

    Find genes that share ontologies with ZNF562           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for ZNF562 (ZN562)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for ZNF562 gene (3 alternative transcripts): 
    NM_001130031.1  NM_001130032.1  NM_017656.3  

    Unigene Cluster for ZNF562:

    Zinc finger protein 562
    Hs.371107  [show with all ESTs]
    Unigene Representative Sequence: NM_001130031
    12 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000293648(uc002mlx.3) ENST00000453372(uc002mly.3 uc010xkt.2 uc010xkv.1 uc010xkw.1)
    ENST00000590155 ENST00000585688 ENST00000587392 ENST00000588653 ENST00000589542
    ENST00000585350 ENST00000448622(uc010xks.2 uc010xku.2) ENST00000541032
    ENST00000453792 ENST00000537617
    miRNA
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    8 qRT-PCR Assays for microRNAs that regulate ZNF562:
    hsa-miR-181c hsa-miR-1260b hsa-miR-181a hsa-miR-181d hsa-miR-1260 hsa-miR-188-3p hsa-miR-181b hsa-miR-4262
    SwitchGear 3'UTR luciferase reporter plasmidZNF562 3' UTR sequence
    Inhib. RNA
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    OriGene RNAi products in human, mouse, rat for ZNF562
    Predesigned siRNA for gene silencing in human, mouse, rat ZNF562
    Clone
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    OriGene clones in human, mouse for ZNF562 (see all 14)
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 3): ZNF562 (NM_001130031)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ZNF562
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF562
    Primer
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    OriGene qSTAR qPCR primer pairs in human, mouse for ZNF562
    Pre-validated RT2 qPCR Primer Assay in human, mouse / rat ZNF562
      QuantiTect SYBR Green Assays in human, mouse, rat ZNF562
      QuantiFast Probe-based Assays in human, mouse, rat ZNF562

    Additional mRNA sequence: 

    AK000086.1 AK127419.1 AK297446.1 AK300115.1 AK303038.1 AK304370.1 AY346375.1 BC109062.2 

    9 DOTS entries:

    DT.410376  DT.95118941  DT.454230  DT.100752178  DT.101961080  DT.100752180  DT.424845  DT.100744600 
    DT.121447077 

    Selected AceView cDNA sequences (see all 95):

    BX446351 AA468747 BM970703 AI660344 BM972677 AA468767 AI001007 AI919165 
    AW002691 AA906706 AW002696 AI655255 AI580903 BE858098 AW262262 AI655988 
    AI753280 AA224581 CR613353 BM972735 CK299087 BQ301014 AA513771 BP351030 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for ZNF562 (see all 6)    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4a · 4b ^ 5a · 5b ^ 6a · 6b · 6c · 6d
    SP1:                          -                                             
    SP2:                          -                                             
    SP3:                          -           -     -                           
    SP4:                          -     -                                       
    SP5:                                                                        


    ECgene alternative splicing isoforms for ZNF562

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    ZNF562 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CCTATAGTTT
    ZNF562 Expression
    About this image

    ZNF562 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    ZNF562 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.371107
        Custom PCR Arrays for ZNF562
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF562

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    ENSEMBL Gene Tree for ZNF562 (if available)
    TreeFam Gene Tree for ZNF562 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for ZNF562 gene
    ZNF8122  ZNF7782  ZNF2662  ZNF4262  ZNF5602  ZNF8462  ZNF1212  ZNF5612  
    ZNF5592  
    Selected SIMAP similar genes for ZNF562 using alignment to 9 protein entries:     ZN562_HUMAN (see all proteins) (see all similar genes):
    ZNF812    ZNF561    ZNF78L1    ZNF274    ZNF625-ZNF20    ZNF81
    ZFS-4    ZNF208    MGC12518    ZNF84    FIK    ZFP90
    ZNF788    ZNF268    ZNF615    ZNF169    ZNF614    ZNF721

    Find genes that share paralogs with ZNF562           About GenesLikeMe


    2 Pseudogenes.org Pseudogenes for ZNF562
    PGOHUM00000250558 PGOHUM00000234152


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for ZNF562 (see all 701)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 19 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs711888341,2
    C--9351631(-) GTAGG-/TT/T  
      TTTTTT
    TTTTT
    3 -- int12NA 4
    rs1412036861,2
    --9758855(+) CTCCAA/TAACAT 3 -- int10--------
    rs1435604811,2
    C--9759044(+) TGCAAC/TCTTGG 3 -- int10--------
    rs1509803021,2
    --9759231(+) ACCCCC/TACCTC 3 -- int10--------
    rs1408992291,2
    --9759288(+) CACATC/TTGTTT 3 -- int10--------
    rs1159274341,2
    C,F--9759303(+) AAAGCG/ACCTTT 3 -- int11Minor allele frequency- A:0.03WA 118
    rs1501665321,2
    C--9759335(+) TTTTTG/TTTTTG 3 -- ut310--------
    rs1896296281,2
    --9759503(+) AGGTGA/CAGTTC 3 -- ut310--------
    rs1807439361,2
    --9759513(+) CTAGGG/TATTGA 3 -- ut310--------
    rs1162937441,2
    C,F--9759537(+) ATAAAC/TATGAT 3 -- ut311Minor allele frequency- T:0.03WA 118

    HapMap Linkage Disequilibrium report for ZNF562 (9759330 - 9785776 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for ZNF562:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2718156CNV Deletion23290073
    esv2661640CNV Deletion23128226

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing ZNF562
    DNA2.0 Custom Variant and Variant Library Synthesis for ZNF562

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    Find genes that share disorders with ZNF562           About GenesLikeMe

    Genetic Association Database (GAD): ZNF562
    Human Genome Epidemiology (HuGE) Navigator: ZNF562 (1 document)

    Export disorders for ZNF562 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for ZNF562 gene integrated from 10 sources:
    (articles sorted by number of sources associating them with ZNF562)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
    2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    3. Ubiquitin-mediated proteolysis of HuR by heat shock. (PubMed id 19322201)1 Abdelmohsen K....Gorospe M. (EMBO J. 2009)
    4. Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions. (PubMed id 15342556)1 Suzuki Y.... Sugano S. (Genome Res. 2004)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    6. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
    7. Gene expression profile of human bone marrow stromal cells: high-throughput expressed sequence tag sequencing analysis. (PubMed id 11827452)1 Jia L....Francomano C.A. (Genomics 2002)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 54811 HGNC: 25950 AceView: ZNF562 Ensembl:ENSG00000171466 euGenes: HUgn54811
    ECgene: ZNF562 H-InvDB: ZNF562

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for ZNF562 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for ZNF562 gene:
    Search GeneIP for patents involving ZNF562

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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