Free for academic non-profit institutions. Other users need a Commercial license

Aliases for ZNF562 Gene

Aliases for ZNF562 Gene

  • Zinc Finger Protein 562 2 3 5

External Ids for ZNF562 Gene

Previous GeneCards Identifiers for ZNF562 Gene

  • GC19M009621
  • GC19M009759
  • GC19M009340

Summaries for ZNF562 Gene

GeneCards Summary for ZNF562 Gene

ZNF562 (Zinc Finger Protein 562) is a Protein Coding gene. Among its related pathways are Gene Expression. GO annotations related to this gene include nucleic acid binding. An important paralog of this gene is ZNF561.

UniProtKB/Swiss-Prot for ZNF562 Gene

  • May be involved in transcriptional regulation.

Additional gene information for ZNF562 Gene

No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF562 Gene

Genomics for ZNF562 Gene

Regulatory Elements for ZNF562 Gene

Enhancers for ZNF562 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH19H010100 1.8 FANTOM5 ENCODE dbSUPER 60.5 -429.1 -429086 8.3 HDGF FOXA2 PKNOX1 MLX ZFP64 ARID4B SIN3A DMAP1 YBX1 ZNF2 ILF3 ZNF699 ZNF317 KRI1 FBXL12 LOC100419831 ZNF561 ZNF559 PPAN ZNF562
GH19H010379 1.1 ENCODE 37.1 -705.2 -705225 1.9 HDGF PKNOX1 ZFP64 ARID4B SIN3A DMAP1 ZNF2 YY1 ZNF416 ZNF207 ILF3 KRI1 FBXL12 PPAN RAVER1 DNMT1 LOC100419831 ZNF561 ZNF426 TIMM29
GH19H010651 1.4 ENCODE dbSUPER 22.4 -978.9 -978913 5.1 MLX FEZF1 DMAP1 YY1 SLC30A9 ZNF143 SP3 NFYC ZC3H11A MEF2D ILF3 ZNF627 LOC100419831 FBXL12 ZNF562 SLC44A2 ILF3-AS1 KRI1 ZNF887P QTRT1
GH19H010331 1.1 ENCODE 19.5 -658.4 -658375 3.7 HDGF PKNOX1 FOXA2 ARNT ARID4B SIN3A FEZF1 DMAP1 ZNF2 ZBTB7B ILF3 LOC100419831 RAVER1 ZNF846 ZNF266 ZNF562 ZNF561 FBXL12 LOC100418883 ZNF177
GH19H010514 1.6 FANTOM5 ENCODE dbSUPER 12.4 -841.9 -841915 5.2 FOXA2 ZNF121 GLIS2 KLF7 SP3 ZNF623 ZNF610 GLIS1 WT1 FOXP1 S1PR5 LOC100419831 ILF3 KRI1 QTRT1 ATG4D ZNF846 CDKN2D SLC44A2 ZNF562
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around ZNF562 on UCSC Golden Path with GeneCards custom track

Promoters for ZNF562 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000106908 401 1799 PKNOX1 ARNT ARID4B SIN3A DMAP1 YY1 CBX5 ZNF143 SP3 ZHX2

Genomic Locations for ZNF562 Gene

Genomic Locations for ZNF562 Gene
33,495 bases
Minus strand

Genomic View for ZNF562 Gene

Genes around ZNF562 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF562 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF562 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF562 Gene

Proteins for ZNF562 Gene

  • Protein details for ZNF562 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Zinc finger protein 562
    Protein Accession:
    Secondary Accessions:
    • Q32MN2
    • Q9NXS5

    Protein attributes for ZNF562 Gene

    426 amino acids
    Molecular mass:
    48563 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ZNF562 Gene


neXtProt entry for ZNF562 Gene

Post-translational modifications for ZNF562 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for ZNF562 Gene

Domains & Families for ZNF562 Gene

Gene Families for ZNF562 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins
  • Transcription factors

Protein Domains for ZNF562 Gene

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
genes like me logo Genes that share domains with ZNF562: view

Function for ZNF562 Gene

Molecular function for ZNF562 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Phenotypes From GWAS Catalog for ZNF562 Gene

Gene Ontology (GO) - Molecular Function for ZNF562 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF562: view

Phenotypes for ZNF562 Gene

genes like me logo Genes that share phenotypes with ZNF562: view

miRNA for ZNF562 Gene

miRTarBase miRNAs that target ZNF562

Clone Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF562 Gene

Localization for ZNF562 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF562 Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZNF562 gene
Compartment Confidence
nucleus 5
cytosol 2

Subcellular locations from the

Human Protein Atlas (HPA)

Gene Ontology (GO) - Cellular Components for ZNF562 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular IEA --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF562: view

Pathways & Interactions for ZNF562 Gene

SuperPathways for ZNF562 Gene

SuperPathway Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF562: view

Pathways by source for ZNF562 Gene

2 Reactome pathways for ZNF562 Gene

Gene Ontology (GO) - Biological Process for ZNF562 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF562: view

No data available for SIGNOR curated interactions for ZNF562 Gene

Drugs & Compounds for ZNF562 Gene

No Compound Related Data Available

Transcripts for ZNF562 Gene

Unigene Clusters for ZNF562 Gene

Zinc finger protein 562:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF562 Gene

ExUns: 1a · 1b ^ 2 ^ 3 ^ 4a · 4b ^ 5a · 5b ^ 6a · 6b · 6c · 6d
SP1: -
SP2: -
SP3: - - -
SP4: - -
SP6: - - -

Relevant External Links for ZNF562 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ZNF562 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ZNF562 Gene

NURSA nuclear receptor signaling pathways regulating expression of ZNF562 Gene:


SOURCE GeneReport for Unigene cluster for ZNF562 Gene:


Evidence on tissue expression from TISSUES for ZNF562 Gene

  • Intestine(4.2)
genes like me logo Genes that share expression patterns with ZNF562: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZNF562 Gene

Orthologs for ZNF562 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF562 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia ZNF562 34
  • 99 (a)
(Mus musculus)
Mammalia Zfp266 34
  • 41 (a)
(Canis familiaris)
Mammalia -- 34
  • 35 (a)
(Bos Taurus)
Mammalia -- 34
  • 23 (a)
Species where no ortholog for ZNF562 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF562 Gene

Gene Tree for ZNF562 (if available)
Gene Tree for ZNF562 (if available)

Paralogs for ZNF562 Gene

(500) SIMAP similar genes for ZNF562 Gene using alignment to 9 proteins: Pseudogenes for ZNF562 Gene

genes like me logo Genes that share paralogs with ZNF562: view

Variants for ZNF562 Gene

Sequence variations from dbSNP and Humsavar for ZNF562 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
rs1000196481 -- 9,669,894(+) CTGTC(A/T)CTACT intron-variant
rs1000224318 -- 9,669,733(+) GCGCG(-/CGCACACACA)CACAC intron-variant
rs1000595317 -- 9,649,837(+) ACCTA(G/T)TTGCA utr-variant-3-prime
rs1000597178 -- 9,665,395(+) CAAGG(C/T)GGACA intron-variant
rs1000672349 -- 9,675,142(+) GCTCC(A/G)GGGCT upstream-variant-2KB, utr-variant-5-prime

Structural Variations from Database of Genomic Variants (DGV) for ZNF562 Gene

Variant ID Type Subtype PubMed ID
nsv963003 CNV duplication 23825009
nsv1060112 CNV gain 25217958
esv3643640 CNV loss 21293372
esv3643639 CNV loss 21293372
esv2718156 CNV deletion 23290073
esv2661640 CNV deletion 23128226

Variation tolerance for ZNF562 Gene

Residual Variation Intolerance Score: 74.3% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.58; 30.53% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ZNF562 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF562 Gene

Disorders for ZNF562 Gene

Relevant External Links for ZNF562

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator
Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for ZNF562 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF562 Gene

Publications for ZNF562 Gene

  1. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose JE … Uhl GR (Molecular medicine (Cambridge, Mass.) 2010) 3 45 60
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 60
  3. Architecture of the human interactome defines protein communities and disease networks. (PMID: 28514442) Huttlin EL … Harper JW (Nature 2017) 3 60
  4. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin EL … Gygi SP (Cell 2015) 3 60
  5. Ubiquitin-mediated proteolysis of HuR by heat shock. (PMID: 19322201) Abdelmohsen K … Gorospe M (The EMBO journal 2009) 3 60

Products for ZNF562 Gene

Sources for ZNF562 Gene

Loading form....