ZNF562 Gene
protein-coding GIFtS: 46
GCID: GC19M009759
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|
zinc finger protein 562
| |
Aliases
for ZNF562 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Zinc Finger Protein 5621 2 | | FLJ200791 |
Export aliases for ZNF562 gene to outside databasesPrevious GC identifers: GC19M009621 GC19M009622 GC19M009340 |
Summaries
for ZNF562 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
UniProtKB/Swiss-Prot: ZN562_HUMAN, Q6V9R5Function: May be involved in transcriptional regulation
|
Genomic Views
for ZNF562 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000019.9 NC_018930.1 NT_011295.11
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the ZNF562 gene promoter:
Nkx3-1 Max1 Pbx1a Nkx3-1 v1 LCR-F1 YY1 C/EBPalpha CHOP-10 FAC1 c-Myc
Other transcription factors
Search SABiosciences Chromatin IP Primers for ZNF562
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZNF562 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 19p13.2 Ensembl cytogenetic band: 19p13.2 HGNC chromosome: 19ZNF562 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 19 GeneLoc Exon Structure GeneLoc location for GC19M009759: view genomic region
(about GC identifiers)
Start:
|
9,759,330 bp from pter |
End:
|
9,785,776 bp from pter |
Size:
|
26,447 bases |
Orientation:
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minus strand |
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Proteins
for ZNF562 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: ZN562_HUMAN, Q6V9R5 (See
protein sequence)Recommended Name: Zinc finger protein 562 Size: 426 amino acids; 48563 Da
Subcellular location: Nucleus (Potential)
Secondary accessions: Q32MN2 Q9NXS5Alternative splicing: 2 isoforms: Q6V9R5-1 Q6V9R5-2 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for ZNF562: NX_Q6V9R5
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q6V9R5
ZNF562 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (3 alternative transcripts):
NP_001123503.1 NP_001123504.1 NP_060126.2
ENSEMBL proteins: ENSP00000293648 ENSP00000410734 ENSP00000464716 ENSP00000466728 ENSP00000468039 ENSP00000466911 ENSP00000466039 ENSP00000468775 ENSP00000411784 ENSP00000442614 ENSP00000440451 ENSP00000445816 Reactome Protein details: Q6V9R5
Human Recombinant Protein Products:
Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table
ZNF562 for ontologies About GeneDecksing
ZNF562 Antibody Products:
Assay Products for ZNF562: |
Protein
Domains /
Families
for ZNF562 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ZNF562 for domains About GeneDecksing
4 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q6V9R5ProtoNet protein and cluster: Q6V9R5 2 Blocks protein families: IPB001909 KRAB box IPB007086 C2H2-type zinc finger signature
UniProtKB/Swiss-Prot: ZN562_HUMAN, Q6V9R5Similarity: Belongs to the krueppel C2H2-type zinc-finger protein familySimilarity: Contains 8 C2H2-type zinc fingersSimilarity: Contains 1 KRAB domain |
Function
for ZNF562 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: ZN562_HUMAN, Q6V9R5Function: May be involved in transcriptional regulation
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF562 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF562 (see all 3)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 3): ZNF562 (NM_001130031) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ZNF562 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF562 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF562 |
Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table
ZNF562 for ontologies About GeneDecksing
|
Pathways & Interactions
for ZNF562 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Generic Transcription Pathway | |
Pathway sources
See GeneCards unified pathways
Show all pathways
2 
Reactome Pathways for ZNF562
ZNF562 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ZNF562
STRING Interaction
Network Preview (showing 1 interactants - click image to see more details)
1 Interacting protein for ZNF562 (ENSP000004107344) via UniProtKB, MINT, STRING, and/or I2DAbout this table
Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006351 | transcription, DNA-dependent |
IEA | -- | | GO:0006355 | regulation of transcription, DNA-dependent |
IEA | -- |
ZNF562 for ontologies About GeneDecksing
|
Drugs & Compounds
for ZNF562 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for ZNF562
Search CenterWatch for drugs/clinical trials and news about ZNF562 / ZN562
|
Transcripts
for ZNF562 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for ZNF562 gene (3 alternative transcripts): NM_001130031.1 NM_001130032.1 NM_017656.3 Unigene Cluster for ZNF562: Zinc finger protein 562 Hs.371107 [show with all ESTs]Unigene Representative Sequence: NM_00113003112 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000293648(uc002mlx.3) ENST00000453372(uc002mly.3 uc010xkt.2 uc010xkv.1 uc010xkw.1)
ENST00000590155 ENST00000585688 ENST00000587392 ENST00000588653 ENST00000589542
ENST00000585350 ENST00000448622(uc010xks.2 uc010xku.2) ENST00000541032
ENST00000453792 ENST00000537617
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF562 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF562 (see all 3)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 3): ZNF562 (NM_001130031) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ZNF562 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF562 |
Additional cDNA sequence: AK000086.1 AK127419.1 AK297446.1 AK300115.1 AK303038.1 AK304370.1 AY346375.1 BC109062.2 9 DOTS entries: DT.410376 DT.95118941 DT.454230 DT.100752178 DT.101961080 DT.100752180 DT.424845 DT.100744600 DT.121447077 24/95 AceView cDNA sequences (see all 95): BP351030 BX446351 AA468767 AW002691 AA906706 CK299087 AI580903 BQ301014 BM972735 AI655255 AW002696 AI660344 BX332481 C01104 AI655988 AI001007 CR613353 AI919165 AI753280 AW262262 AA513771 BE858098 BM972677 AA224581
GeneLoc Exon Structure
5/6 Alternative Splicing Database (ASD) splice patterns (SP) for ZNF562 (see all 6) About this scheme
| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3 | ^ | 4a | · | 4b | ^ | 5a | · | 5b | ^ | 6a | · | 6b | · | 6c | · | 6d |
|---|
|
| SP1: | | | | | | | | | - | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | - | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | - | | | | - | | - | | | | | | | | | | |
| SP4: | | | | | | | | | - | | - | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for ZNF562
|
Expression
for ZNF562 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ZNF562 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CCTATAGTTT
About this image
See ZNF562 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for ZNF562
SOURCE GeneReport for Unigene cluster: Hs.371107
SABiosciences Custom PCR Arrays for ZNF562
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZNF562
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat ZNF562 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZNF562 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZNF562 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF562 |
Orthologs
for ZNF562 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
--
ENSEMBL Gene Tree for ZNF562 (if available)
TreeFam Gene Tree for ZNF562 (if available) |
Paralogs
for ZNF562 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for ZNF562 gene
- ZNF8122 ZNF7782 ZNF2662 ZNF4262 ZNF5602 ZNF8462 ZNF1212 ZNF5612
- ZNF5592
18/488 SIMAP similar genes for ZNF562 using alignment to 9 protein entries: ZN562_HUMAN (see all proteins)
(see all similar genes):ZNF812 ZNF561 ZNF78L1 ZNF81 ZFS-4 MGC12518
ZNF84 ZFP90 ZNF268 ZSCAN31 ZNF721 KRBOX4
ZFS-6 ZNF56 ZNF761 ZNF331 ZNF175 ZNF227
ZNF562 for paralogs About GeneDecksing
2 Pseudogenes.org Pseudogenes for ZNF562
PGOHUM00000250558 PGOHUM00000234152
|
Genomic Variants
for ZNF562 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 19 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for ZNF562 (9759330 - 9785776 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for ZNF562: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ZNF562 |
|
Disorders
/ Diseases
for ZNF562 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
 ZNF562 for disorders About MalaCards
ZNF562 for disorders About GeneDecksing
Human Genome Epidemiology (HuGE) Navigator: ZNF562 (1 document)
Export disorders for ZNF562 gene to outside databases
|
Publications
for ZNF562 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ZNF562 gene integrated from 9 sources:
(articles sorted by number of sources associating them with ZNF562) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1 Rose J.E....Uhl G.R. (2010)
- Ubiquitin-mediated proteolysis of HuR by heat shock. (PubMed id 19322201)1 Abdelmohsen K....Gorospe M. (2009)
- Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions. (PubMed id 15342556)1 Suzuki Y.... Sugano S. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
- Gene expression profile of human bone marrow stromal cells: high-throughput expressed sequence tag sequencing analysis. (PubMed id 11827452)1 Jia L....Francomano C.A. (2002)
|
External Searches for ZNF562 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing ZNF562 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing ZNF562 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing ZNF562 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for ZNF562 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for ZNF562 gene:
Search GeneIP for patents involving ZNF562
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for ZNF562 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for ZNF562 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ZNF562 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZNF562 | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for ZNF562 | | OriGene 3'-UTR Clone for ZNF562 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF562 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF562 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for ZNF562 | | OriGene Custom Protein Services for ZNF562 | | | OriGene Custom Immunoassay Development | | |
| |
 |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ZNF562 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ZNF562 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZNF562 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ZNF562 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZNF562 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZNF562 |
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| | | | Search Tocris compounds for ZNF562 |
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 | | | ZNF562 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF562 |
|  |  |  | | | | Search ThermoFisher Antibodies for ZNF562 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF562 |
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