Free for academic non-profit institutions. Other users need a Commercial license

Aliases for ZNF559 Gene

Aliases for ZNF559 Gene

  • Zinc Finger Protein 559 2 3
  • Putative Protein Product Of Nbla00121 3
  • NBLA00121 3

External Ids for ZNF559 Gene

Previous GeneCards Identifiers for ZNF559 Gene

  • GC19P009296
  • GC19P009434
  • GC19P009016

Summaries for ZNF559 Gene

GeneCards Summary for ZNF559 Gene

ZNF559 (Zinc Finger Protein 559) is a Protein Coding gene. Among its related pathways are Gene Expression. GO annotations related to this gene include nucleic acid binding. An important paralog of this gene is ZNF426.

UniProtKB/Swiss-Prot for ZNF559 Gene

  • May be involved in transcriptional regulation

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF559 Gene

Genomics for ZNF559 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for ZNF559 Gene

Chromosome:
19
Start:
9,323,772 bp from pter
End:
9,351,162 bp from pter
Size:
27,391 bases
Orientation:
Plus strand

Genomic View for ZNF559 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZNF559 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF559 Gene

No data available for Regulatory Elements for ZNF559 Gene

Proteins for ZNF559 Gene

  • Protein details for ZNF559 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9BR84-ZN559_HUMAN
    Recommended name:
    Zinc finger protein 559
    Protein Accession:
    Q9BR84
    Secondary Accessions:
    • K7EMG6

    Protein attributes for ZNF559 Gene

    Size:
    538 amino acids
    Molecular mass:
    62318 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ZNF559 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZNF559 Gene

Proteomics data for ZNF559 Gene at MOPED

Post-translational modifications for ZNF559 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for ZNF559 Gene

Domains & Families for ZNF559 Gene

Gene Families for ZNF559 Gene

Protein Domains for ZNF559 Gene

Suggested Antigen Peptide Sequences for ZNF559 Gene

Graphical View of Domain Structure for InterPro Entry

Q9BR84

UniProtKB/Swiss-Prot:

ZN559_HUMAN :
  • Contains 1 KRAB domain.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 13 C2H2-type zinc fingers.
Domain:
  • Contains 1 KRAB domain.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 13 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF559: view

Function for ZNF559 Gene

Molecular function for ZNF559 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation

Gene Ontology (GO) - Molecular Function for ZNF559 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding --
GO:0003677 DNA binding IEA --
GO:0005515 protein binding IPI 16189514
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF559: view

Phenotypes for ZNF559 Gene

GenomeRNAi human phenotypes for ZNF559:
genes like me logo Genes that share phenotypes with ZNF559: view

Animal Model Products

CRISPR Products

miRNA for ZNF559 Gene

miRTarBase miRNAs that target ZNF559

No data available for Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF559 Gene

Localization for ZNF559 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF559 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF559 Gene COMPARTMENTS Subcellular localization image for ZNF559 gene
Compartment Confidence
nucleus 3

Gene Ontology (GO) - Cellular Components for ZNF559 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF559: view

Pathways & Interactions for ZNF559 Gene

SuperPathways for ZNF559 Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF559: view

Pathways by source for ZNF559 Gene

2 Reactome pathways for ZNF559 Gene

Gene Ontology (GO) - Biological Process for ZNF559 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF559: view

No data available for SIGNOR curated interactions for ZNF559 Gene

Drugs & Compounds for ZNF559 Gene

No Compound Related Data Available

Transcripts for ZNF559 Gene

Unigene Clusters for ZNF559 Gene

Zinc finger protein 559:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZNF559

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF559 Gene

ExUns: 1a · 1b · 1c ^ 2a · 2b · 2c · 2d ^ 3a · 3b · 3c ^ 4 ^ 5 ^ 6a · 6b ^ 7a · 7b ^ 8 ^ 9a · 9b ^ 10a · 10b · 10c · 10d · 10e · 10f ^ 11a ·
SP1: - - - - - - - - - - - - - -
SP2: - - - - - - - - - -
SP3: - - - - - - - - - - - - - - -
SP4: - - - - - - - - - - - - - - - -
SP5: - - - - - - - - - - - - - - - - -
SP6: - - - - - - - - - -
SP7: - - - - - - - -
SP8: - - - - -
SP9: - - - - - - - - - - - - - - - - -
SP10: - - - - - - - - - - - - - - - - - -
SP11: - - - - - - - - - - - - -
SP12: - - - - - - - - - -
SP13: - - - - - - - -
SP14: - - - - - - - - -
SP15: - - - -
SP16: - - -
SP17: - - - - - - - - - - - - - -
SP18: - - - - - - - - - - - - - - - - - -
SP19: - - - - - - - - - - - - - - - - - - -
SP20: - - - - -
SP21: - - - - -
SP22: - - - -
SP23: - - - - - - - -
SP24: - - - - - - - - - - - - - - -
SP25: - -

ExUns: 11b · 11c · 11d · 11e · 11f · 11g · 11h · 11i · 11j
SP1:
SP2:
SP3:
SP4:
SP5:
SP6:
SP7:
SP8:
SP9:
SP10:
SP11:
SP12:
SP13:
SP14:
SP15:
SP16:
SP17:
SP18:
SP19:
SP20:
SP21:
SP22:
SP23:
SP24:
SP25:

Relevant External Links for ZNF559 Gene

GeneLoc Exon Structure for
ZNF559
ECgene alternative splicing isoforms for
ZNF559

Expression for ZNF559 Gene

mRNA expression in normal human tissues for ZNF559 Gene

mRNA differential expression in normal tissues according to GTEx for ZNF559 Gene

This gene is overexpressed in Brain - Cerebellar Hemisphere (x4.2).

Protein differential expression in normal tissues from HIPED for ZNF559 Gene

This gene is overexpressed in Adipocyte (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for ZNF559 Gene



SOURCE GeneReport for Unigene cluster for ZNF559 Gene Hs.172979

genes like me logo Genes that share expression patterns with ZNF559: view

Protein tissue co-expression partners for ZNF559 Gene

- Elite partner

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for ZNF559 Gene

Orthologs for ZNF559 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for ZNF559 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF559 35
  • 99.48 (n)
  • 98.77 (a)
-- 36
  • 98 (a)
OneToMany
-- 36
  • 98 (a)
OneToMany
Species with no ortholog for ZNF559:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF559 Gene

ENSEMBL:
Gene Tree for ZNF559 (if available)
TreeFam:
Gene Tree for ZNF559 (if available)

Paralogs for ZNF559 Gene

Paralogs for ZNF559 Gene

(540) SIMAP similar genes for ZNF559 Gene using alignment to 10 proteins:

genes like me logo Genes that share paralogs with ZNF559: view

Variants for ZNF559 Gene

Sequence variations from dbSNP and Humsavar for ZNF559 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type MAF
rs10416297 -- 9,322,204(+) caatc(A/G)acact upstream-variant-2KB
rs35774793 -- 9,322,183(+) GCTCA(-/G)GGTTT upstream-variant-2KB
rs55904221 -- 9,322,081(+) TTGGA(A/G)AACCT upstream-variant-2KB
rs56201147 -- 9,321,991(+) ATGGC(A/G)CGGGA upstream-variant-2KB
rs56276160 -- 9,321,863(+) CTACC(C/T)CCTCC upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for ZNF559 Gene

Variant ID Type Subtype PubMed ID
nsv911020 CNV Gain 21882294
nsv523472 CNV Loss 19592680
nsv521091 CNV Loss 19592680
esv2678521 CNV Deletion 23128226
nsv911023 CNV Loss 21882294
esv2674742 CNV Deletion 23128226
nsv819521 CNV Gain 19587683

Variation tolerance for ZNF559 Gene

Residual Variation Intolerance Score: 96.67% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 5.00; 68.39% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ZNF559 Gene

HapMap Linkage Disequilibrium report
ZNF559
Human Gene Mutation Database (HGMD)
ZNF559

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF559 Gene

Disorders for ZNF559 Gene

Relevant External Links for ZNF559

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ZNF559
genes like me logo Genes that share disorders with ZNF559: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF559 Gene

Publications for ZNF559 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 67
  2. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 67
  3. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 67
  4. Towards a proteome-scale map of the human protein-protein interaction network. (PMID: 16189514) Rual J.F. … Vidal M. (Nature 2005) 67
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 67

Products for ZNF559 Gene

Sources for ZNF559 Gene

Back to Top

Content