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Aliases for ZNF556 Gene

Aliases for ZNF556 Gene

  • Zinc Finger Protein 556 2 3

External Ids for ZNF556 Gene

Previous GeneCards Identifiers for ZNF556 Gene

  • GC19P002819
  • GC19P002820
  • GC19P002638

Summaries for ZNF556 Gene

GeneCards Summary for ZNF556 Gene

ZNF556 (Zinc Finger Protein 556) is a Protein Coding gene. Among its related pathways are Gene Expression and Gene Expression. An important paralog of this gene is ZNF709.

UniProtKB/Swiss-Prot for ZNF556 Gene

  • May be involved in transcriptional regulation

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF556 Gene

Genomics for ZNF556 Gene

Regulatory Elements for ZNF556 Gene

Genomic Location for ZNF556 Gene

Start:
2,867,335 bp from pter
End:
2,883,445 bp from pter
Size:
16,111 bases
Orientation:
Plus strand

Genomic View for ZNF556 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZNF556 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF556 Gene

Proteins for ZNF556 Gene

  • Protein details for ZNF556 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9HAH1-ZN556_HUMAN
    Recommended name:
    Zinc finger protein 556
    Protein Accession:
    Q9HAH1
    Secondary Accessions:
    • Q96GM3

    Protein attributes for ZNF556 Gene

    Size:
    456 amino acids
    Molecular mass:
    51581 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZNF556 Gene

Proteomics data for ZNF556 Gene at MOPED

Post-translational modifications for ZNF556 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF556 Gene

ENSEMBL proteins:
Reactome Protein details:
REFSEQ proteins:

Antibody Products

No data available for DME Specific Peptides for ZNF556 Gene

Domains for ZNF556 Gene

Gene Families for ZNF556 Gene

HGNC:
  • ZNF :Zinc fingers, C2H2-type

Suggested Antigen Peptide Sequences for ZNF556 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q9HAH1

UniProtKB/Swiss-Prot:

ZN556_HUMAN :
  • Q9HAH1
Domain:
  • Contains 1 KRAB domain.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 9 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF556: view

Function for ZNF556 Gene

Molecular function for ZNF556 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation

Gene Ontology (GO) - Molecular Function for ZNF556 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding --
GO:0003677 DNA binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF556: view

Phenotypes for ZNF556 Gene

GenomeRNAi human phenotypes for ZNF556:
genes like me logo Genes that share phenotypes with ZNF556: view

Animal Model Products

CRISPR Products

miRNA for ZNF556 Gene

miRTarBase miRNAs that target ZNF556

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZNF556

In Situ Assay Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for ZNF556 Gene

Localization for ZNF556 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF556 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF556 Gene COMPARTMENTS Subcellular localization image for ZNF556 gene
Compartment Confidence
nucleus 4
cytosol 2

Gene Ontology (GO) - Cellular Components for ZNF556 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF556: view

Pathways for ZNF556 Gene

SuperPathways for ZNF556 Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF556: view

Pathways by source for ZNF556 Gene

2 Reactome pathways for ZNF556 Gene

Gene Ontology (GO) - Biological Process for ZNF556 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF556: view

Transcripts for ZNF556 Gene

mRNA/cDNA for ZNF556 Gene

(3) Additional mRNA sequences :
(2) REFSEQ mRNAs :
(6) Selected AceView cDNA sequences:
(3) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ZNF556 Gene

Zinc finger protein 556:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZNF556

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF556 Gene

ExUns: 1 ^ 2 ^ 3 ^ 4a · 4b · 4c
SP1:
SP2:
SP3:

Relevant External Links for ZNF556 Gene

GeneLoc Exon Structure for
ZNF556
ECgene alternative splicing isoforms for
ZNF556

Expression for ZNF556 Gene

mRNA expression in normal human tissues for ZNF556 Gene

mRNA differential expression in normal tissues according to GTEx for ZNF556 Gene

This gene is overexpressed in Brain - Cerebellar Hemisphere (10.2), Ovary (7.7), Brain - Cerebellum (7.4), and Muscle - Skeletal (5.3).

Protein differential expression in normal tissues for ZNF556 Gene

This gene is overexpressed in Bone (68.3).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for ZNF556 Gene

SOURCE GeneReport for Unigene cluster for ZNF556 Gene Hs.287433

genes like me logo Genes that share expressions with ZNF556: view

Expression partners for ZNF556 Gene

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for ZNF556 Gene

Orthologs for ZNF556 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZNF556 Gene

Organism Taxonomy Gene Similarity Type Details
dog
(Canis familiaris)
Mammalia ZNF556 35
  • 78.23 (n)
  • 67.65 (a)
ZNF556 36
  • 58 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia ZNF556 35
  • 99.12 (n)
  • 98.46 (a)
ZNF556 36
  • 98 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 29 (a)
ManyToMany
-- 36
  • 34 (a)
ManyToMany
-- 36
  • 31 (a)
ManyToMany
-- 36
  • 31 (a)
ManyToMany
mouse
(Mus musculus)
Mammalia C330013J21Rik 36
  • 36 (a)
ManyToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 31 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia -- 36
  • 25 (a)
OneToMany
zebrafish
(Danio rerio)
Actinopterygii CR388132.2 36
  • 25 (a)
ManyToMany
CT573234.2 36
  • 25 (a)
ManyToMany
Species with no ortholog for ZNF556:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ZNF556 Gene

ENSEMBL:
Gene Tree for ZNF556 (if available)
TreeFam:
Gene Tree for ZNF556 (if available)

Paralogs for ZNF556 Gene

Selected SIMAP similar genes for ZNF556 Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with ZNF556: view

Variants for ZNF556 Gene

Sequence variations from dbSNP and Humsavar for ZNF556 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type MAF
rs482730 -- 2,872,081(+) gtgta(C/T)aggat intron-variant
rs482766 -- 2,872,099(+) gaaag(C/T)ggact intron-variant
rs487458 -- 2,872,601(+) tctta(C/T)ttgat intron-variant
rs498796 -- 2,872,754(+) gtgga(A/G)gttgc intron-variant
rs499791 -- 2,872,887(+) cagca(C/T)tttgg intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF556 Gene

Variant ID Type Subtype PubMed ID
nsv910692 CNV Loss 21882294
nsv509715 CNV Insertion 20534489

Relevant External Links for ZNF556 Gene

HapMap Linkage Disequilibrium report
ZNF556

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF556 Gene

Disorders for ZNF556 Gene

No disorders were found for ZNF556 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for ZNF556 Gene

Publications for ZNF556 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  4. Ubiquitin-mediated proteolysis of HuR by heat shock. (PMID: 19322201) Abdelmohsen K. … Gorospe M. (EMBO J. 2009) 3
  5. An atlas of combinatorial transcriptional regulation in mouse and man. (PMID: 20211142) Ravasi T. … Hayashizaki Y. (Cell 2010) 3

Products for ZNF556 Gene

Sources for ZNF556 Gene

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