ZNF555 Gene
protein-coding GIFtS: 45
GCID: GC19P002841
|
|
zinc finger protein 555
| |
Aliases
for ZNF555 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Zinc Finger Protein 5551 2 | | MGC267071 |
Export aliases for ZNF555 gene to outside databasesPrevious GC identifers: GC19P002793 GC19P002794 GC19P002612 |
Summaries
for ZNF555 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
UniProtKB/Swiss-Prot: ZN555_HUMAN, Q8NEP9Function: May be involved in transcriptional regulation
|
Genomic Views
for ZNF555 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000019.9 NC_018930.1 NT_011255.14
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the ZNF555 gene promoter:
AP-1 HTF p300
Other transcription factors
Search SABiosciences Chromatin IP Primers for ZNF555
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZNF555 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 19p13.3 Ensembl cytogenetic band: 19p13.3 HGNC chromosome: 19ZNF555 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 19 GeneLoc Exon Structure GeneLoc location for GC19P002841: view genomic region
(about GC identifiers)
Start:
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2,841,433 bp from pter |
End:
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2,860,482 bp from pter |
Size:
|
19,050 bases |
Orientation:
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plus strand |
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Proteins
for ZNF555 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: ZN555_HUMAN, Q8NEP9 (See
protein sequence)Recommended Name: Zinc finger protein 555 Size: 628 amino acids; 73084 Da
Subcellular location: Nucleus (Probable)
Secondary accessions: Q8NA46 Q96MP1Alternative splicing: 2 isoforms: Q8NEP9-1 Q8NEP9-2 Explore the universe of human proteins at neXtProt for ZNF555: NX_Q8NEP9
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q8NEP9
ZNF555 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_001166246.1 NP_690004.4
ENSEMBL proteins: ENSP00000334853 ENSP00000466982 ENSP00000467893 Reactome Protein details: Q8NEP9
Human Recombinant Protein Products:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005634 | nucleus |
IEA | -- |
ZNF555 for ontologies About GeneDecksing
ZNF555 Antibody Products:
Assay Products for ZNF555: |
Protein
Domains /
Families
for ZNF555 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ZNF555 for domains About GeneDecksing
4 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q8NEP9ProtoNet protein and cluster: Q8NEP9 1 Blocks protein family: IPB001909 KRAB box
UniProtKB/Swiss-Prot: ZN555_HUMAN, Q8NEP9Similarity: Belongs to the krueppel C2H2-type zinc-finger protein familySimilarity: Contains 15 C2H2-type zinc fingersSimilarity: Contains 1 KRAB domain |
Function
for ZNF555 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: ZN555_HUMAN, Q8NEP9Function: May be involved in transcriptional regulation
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF555 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF555 (see all 3)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 2): ZNF555 (NM_001172775) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ZNF555 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF555 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF555 |
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table
ZNF555 for ontologies About GeneDecksing
|
Pathways & Interactions
for ZNF555 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Generic Transcription Pathway | |
Pathway sources
See GeneCards unified pathways
Show all pathways
2 
Reactome Pathways for ZNF555
ZNF555 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ZNF555
Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006351 | transcription, DNA-dependent |
IEA | -- | | GO:0006355 | regulation of transcription, DNA-dependent |
IEA | -- |
ZNF555 for ontologies About GeneDecksing
|
Drugs & Compounds
for ZNF555 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for ZNF555
Search CenterWatch for drugs/clinical trials and news about ZNF555 / ZN555
|
Transcripts
for ZNF555 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for ZNF555 gene (2 alternative transcripts): NM_001172775.1 NM_152791.4 Unigene Cluster for ZNF555: Zinc finger protein 555 Hs.47712 [show with all ESTs]Unigene Representative Sequence: NM_1527913 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000334241(uc002lwn.4 uc002lwo.3) ENST00000585966 ENST00000591539
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF555 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF555 (see all 3)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 2): ZNF555 (NM_001172775) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ZNF555 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF555 |
Additional cDNA sequence: AF052118.1 AK056659.1 AK093163.1 AK123888.1 AK292954.1 AL832140.1 BC022022.2 BX647423.1 5 DOTS entries: DT.40291078 DT.100019126 DT.95356597 DT.100786337 DT.407662 24/44 AceView cDNA sequences (see all 44): BM127722 BM819236 CK819098 BM825796 CB215961 AA774606 BX647423 AL539396 BX445136 BX445135 BG719533 BC022022 BM127975 AK056659 BG284252 AK093163 CK819099 AA773786 AW852237 AL832140 BE904252 AX747966 BG716971 NM_152791
GeneLoc Exon Structure
3 Alternative Splicing Database (ASD) splice patterns (SP) for ZNF555 About this scheme
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2 | ^ | 3 | ^ | 4a | · | 4b | · | 4c |
|---|
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| SP1: | | | | | | | | | | | | | | | | | |
| SP2: | | | | | - | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for ZNF555
|
Expression
for ZNF555 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ZNF555 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TTAACATAAG
About this image
See ZNF555 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for ZNF555
SOURCE GeneReport for Unigene cluster: Hs.47712
SABiosciences Custom PCR Arrays for ZNF555
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZNF555
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat ZNF555 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZNF555 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZNF555 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF555 |
Orthologs
for ZNF555 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for ZNF555 gene from 2/10 species (see all 10) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
fruit fly
(Drosophila melanogaster) |
Insecta |
CG178296 |
-- |
13(a) |
1 → many |
X(519588-522052) |
worm
(Caenorhabditis elegans) |
Secernentea |
F39B2.16 |
-- |
13(a) |
1 → many |
I(14791027-14793977) |
ENSEMBL Gene Tree for ZNF555 (if available)
TreeFam Gene Tree for ZNF555 (if available) |
Paralogs
for ZNF555 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for ZNF555 gene
- ZNF6692 ZNF4902 ZNF5642 ZNF4412 ZNF8782 ENSG000002671792 ZNF142 ENSG000001968262
- ZNF7002 ZNF692 ZNF4402 ZNF4432 ZNF442 ZNF4392 ZNF8232 ZNF4912
- ENSG000001884742 ZNF7092 ZNF6252 ZNF7992 ZNF202 ZNF1012 ZNF7912 ZNF4422
- ZNF4332 ZNF572 ZNF5632 ZNF6272 ENSG000002573552 ZNF1362 ZNF5562 ZNF6702
- ZNF7632 ZNF1242 ZNF6992 ZNF8442 ZNF772
18/512 SIMAP similar genes for ZNF555 using alignment to 3 protein entries: ZN555_HUMAN (see all proteins)
(see all similar genes):KRBOX4 MGC12518 ZFS-4 HZF16 ZNF826P DKFZp666C237
HZF36 ZNF78L1 ZNF833P ZNF669 ZNF789 ZNF761
DKFZp686M04222 ZIC1 ZNF232 ZNF55 ZNF684 ZNF226
ZNF555 for paralogs About GeneDecksing
1 Pseudogenes.org Pseudogene for ZNF555
PGOHUM00000263109
|
Genomic Variants
for ZNF555 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 19 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for ZNF555 (2841433 - 2860482 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for ZNF555
1 Indel: 67436 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ZNF555 |
|
Disorders
/ Diseases
for ZNF555 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications
for ZNF555 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ZNF555 gene, integrated from 9 sources (see all 11):
(articles sorted by number of sources associating them with ZNF555) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (2002)
- The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (2007)
- The LIFEdb database in 2006. (PubMed id 16381901)1 Mehrle A....Wiemann S. (2006)
- From ORFeome to biology: a functional genomics pipeline. (PubMed id 15489336)1 Wiemann S....Poustka A. (2004)
- The DNA sequence and biology of human chromosome 19. (PubMed id 15057824)2 Grimwood J.... Lucas S.M. (2004)
- Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PubMed id 11230166)1 Wiemann S.... Poustka A. (2001)
- DNA cloning using in vitro site-specific recombination. (PubMed id 11076863)1 Hartley J.L....Brasch M.A. (2000)
- Large-scale concatenation cDNA sequencing. (PubMed id 9110174)1 Yu W.... Gibbs R.A. (1997)
|
External Searches for ZNF555 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing ZNF555 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing ZNF555 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing ZNF555 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for ZNF555 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for ZNF555 gene:
Search GeneIP for patents involving ZNF555
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for ZNF555 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for ZNF555 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ZNF555 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZNF555 | | | OriGene Protein Over-expression Lysate for ZNF555 | | Browse OriGene Fluorogenic Cell Assay Kits | | | Browse OriGene siRNAs | | OriGene 3'-UTR Clone for ZNF555 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF555 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF555 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ZNF555 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ZNF555 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZNF555 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ZNF555 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZNF555 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZNF555 |
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 | | | ZNF555 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF555 |
|  |  |  | | | | Search ThermoFisher Antibodies for ZNF555 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF555 |
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