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Aliases for ZNF555 Gene

Aliases for ZNF555 Gene

  • Zinc Finger Protein 555 2 3 5

External Ids for ZNF555 Gene

Previous GeneCards Identifiers for ZNF555 Gene

  • GC19P002793
  • GC19P002794
  • GC19P002612

Summaries for ZNF555 Gene

GeneCards Summary for ZNF555 Gene

ZNF555 (Zinc Finger Protein 555) is a Protein Coding gene. Among its related pathways are Gene Expression. GO annotations related to this gene include nucleic acid binding. An important paralog of this gene is ENSG00000196826.

UniProtKB/Swiss-Prot for ZNF555 Gene

  • May be involved in transcriptional regulation.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF555 Gene

Genomics for ZNF555 Gene

Regulatory Elements for ZNF555 Gene

Enhancers for ZNF555 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around ZNF555 on UCSC Golden Path with GeneCards custom track

Promoters for ZNF555 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around ZNF555 on UCSC Golden Path with GeneCards custom track

Transcription factor binding sites by QIAGEN in the ZNF555 gene promoter:

Genomic Location for ZNF555 Gene

Chromosome:
19
Start:
2,841,435 bp from pter
End:
2,860,484 bp from pter
Size:
19,050 bases
Orientation:
Plus strand

Genomic View for ZNF555 Gene

Genes around ZNF555 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF555 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF555 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF555 Gene

Proteins for ZNF555 Gene

  • Protein details for ZNF555 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8NEP9-ZN555_HUMAN
    Recommended name:
    Zinc finger protein 555
    Protein Accession:
    Q8NEP9
    Secondary Accessions:
    • A8KA89
    • K7EQM2
    • Q8NA46
    • Q96MP1

    Protein attributes for ZNF555 Gene

    Size:
    628 amino acids
    Molecular mass:
    73084 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ZNF555 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZNF555 Gene

Proteomics data for ZNF555 Gene at MOPED

Post-translational modifications for ZNF555 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF555 Gene

No data available for DME Specific Peptides for ZNF555 Gene

Domains & Families for ZNF555 Gene

Gene Families for ZNF555 Gene

Protein Domains for ZNF555 Gene

Suggested Antigen Peptide Sequences for ZNF555 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q8NEP9

UniProtKB/Swiss-Prot:

ZN555_HUMAN :
  • Contains 1 KRAB domain.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 15 C2H2-type zinc fingers.
Domain:
  • Contains 1 KRAB domain.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 15 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF555: view

Function for ZNF555 Gene

Molecular function for ZNF555 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.
genes like me logo Genes that share phenotypes with ZNF555: view

Animal Model Products

CRISPR Products

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF555 Gene

Localization for ZNF555 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF555 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF555 Gene COMPARTMENTS Subcellular localization image for ZNF555 gene
Compartment Confidence
nucleus 5
cytosol 2

No data available for Gene Ontology (GO) - Cellular Components for ZNF555 Gene

Pathways & Interactions for ZNF555 Gene

SuperPathways for ZNF555 Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF555: view

Pathways by source for ZNF555 Gene

2 Reactome pathways for ZNF555 Gene

Gene Ontology (GO) - Biological Process for ZNF555 Gene

None

No data available for SIGNOR curated interactions for ZNF555 Gene

Drugs & Compounds for ZNF555 Gene

No Compound Related Data Available

Transcripts for ZNF555 Gene

Unigene Clusters for ZNF555 Gene

Zinc finger protein 555:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF555 Gene

ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4a · 4b · 4c
SP1:
SP2: -
SP3:

Relevant External Links for ZNF555 Gene

GeneLoc Exon Structure for
ZNF555
ECgene alternative splicing isoforms for
ZNF555

Expression for ZNF555 Gene

mRNA expression in normal human tissues for ZNF555 Gene

Protein differential expression in normal tissues from HIPED for ZNF555 Gene

This gene is overexpressed in Synovial fluid (68.9).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for ZNF555 Gene



SOURCE GeneReport for Unigene cluster for ZNF555 Gene Hs.47712

genes like me logo Genes that share expression patterns with ZNF555: view

Protein tissue co-expression partners for ZNF555 Gene

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ZNF555 Gene

Orthologs for ZNF555 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZNF555 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia ZNF555 35
  • 85.36 (n)
  • 84.94 (a)
ZNF555 36
  • 85 (a)
OneToOne
dog
(Canis familiaris)
Mammalia ZNF555 35
  • 85.81 (n)
  • 86.08 (a)
ZNF555 36
  • 86 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia ZNF555 35
  • 99.15 (n)
  • 98.72 (a)
ZNF555 36
  • 99 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 47 (a)
ManyToMany
-- 36
  • 53 (a)
ManyToMany
-- 36
  • 49 (a)
ManyToMany
-- 36
  • 45 (a)
ManyToMany
mouse
(Mus musculus)
Mammalia Gm14391 36
  • 50 (a)
ManyToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 47 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia -- 36
  • 45 (a)
OneToMany
zebrafish
(Danio rerio)
Actinopterygii CR388132.2 36
  • 42 (a)
ManyToMany
CT573234.2 36
  • 42 (a)
ManyToMany
Species with no ortholog for ZNF555:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ZNF555 Gene

ENSEMBL:
Gene Tree for ZNF555 (if available)
TreeFam:
Gene Tree for ZNF555 (if available)

Paralogs for ZNF555 Gene

(481) SIMAP similar genes for ZNF555 Gene using alignment to 2 proteins:

Pseudogenes.org Pseudogenes for ZNF555 Gene

genes like me logo Genes that share paralogs with ZNF555: view

Variants for ZNF555 Gene

Sequence variations from dbSNP and Humsavar for ZNF555 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
rs17856648 - 2,853,609(+) TGGGA(A/C)AGCTT reference, missense
rs17856649 - 2,852,384(+) GTAGA(A/G)ATCAT reference, missense
rs36012545 - 2,852,475(-) CAGGT(A/G)GAATT reference, missense
rs17851955 - 2,852,645(+) GAACC(A/C)ACAAT reference, missense
rs758769 -- 2,845,585(+) catgt(A/G)taagc intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF555 Gene

Variant ID Type Subtype PubMed ID
nsv910692 CNV Loss 21882294
nsv509715 CNV Insertion 20534489
nsv528638 CNV Gain 19592680
esv27111 CNV Loss 19812545
nsv482209 CNV Loss 20164927
esv2670441 CNV Deletion 23128226

Variation tolerance for ZNF555 Gene

Residual Variation Intolerance Score: 8.69% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.05; 21.46% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for ZNF555 Gene

Disorders for ZNF555 Gene

Relevant External Links for ZNF555

Genetic Association Database (GAD)
ZNF555
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ZNF555

No disorders were found for ZNF555 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF555 Gene

Publications for ZNF555 Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 67
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  3. ZNF555 protein binds to transcriptional activator site of 4qA allele and ANT1: potential implication in Facioscapulohumeral dystrophy. (PMID: 26184877) Kim E. … Pirozhkova I. (Nucleic Acids Res. 2015) 3
  4. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3
  5. The LIFEdb database in 2006. (PMID: 16381901) Mehrle A. … Wiemann S. (Nucleic Acids Res. 2006) 3

Products for ZNF555 Gene

Sources for ZNF555 Gene

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