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Aliases for ZNF555 Gene

Aliases for ZNF555 Gene

  • Zinc Finger Protein 555 2 3 5

External Ids for ZNF555 Gene

Previous GeneCards Identifiers for ZNF555 Gene

  • GC19P002793
  • GC19P002794
  • GC19P002612

Summaries for ZNF555 Gene

GeneCards Summary for ZNF555 Gene

ZNF555 (Zinc Finger Protein 555) is a Protein Coding gene. Among its related pathways are Gene Expression. GO annotations related to this gene include nucleic acid binding. An important paralog of this gene is ZNF791.

UniProtKB/Swiss-Prot for ZNF555 Gene

  • May be involved in transcriptional regulation.

No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF555 Gene

Genomics for ZNF555 Gene

Regulatory Elements for ZNF555 Gene

Enhancers for ZNF555 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH19G003605 1.4 ENCODE dbSUPER 23.9 +766.2 766169 4.6 HDGF PKNOX1 CREB3L1 ARNT SIN3A YBX1 ZNF2 ZNF766 ZNF207 SP3 CACTIN ZNF77 ENSG00000267030 CACTIN-AS1 ZNF555 ENSG00000267769 ENSG00000267205 ZNF554 ENSG00000267138 APBA3
GH19G003150 2 FANTOM5 Ensembl ENCODE dbSUPER 14.4 +312.0 311954 6.0 HDGF FOXA2 PKNOX1 CREB3L1 ARNT SIN3A YBX1 ZNF766 FOS DEK ZNF77 CACTIN GNA15 ZNF555 ENSG00000267138 NCLN FZR1 ENSG00000267205 GNA11 AES
GH19G002887 1.4 FANTOM5 Ensembl ENCODE 17.1 +47.0 46984 2.1 HDAC1 TBP FOXA2 CBX3 CREB3L1 ARID4B RAD21 ZBTB40 ZNF335 GATA2 ZNF555 LOC101928631 ZNF556 ZNF77 ZNF554 THOP1 SLC39A3 LOC100419704 ENSG00000267398
GH19G001939 1.8 FANTOM5 ENCODE dbSUPER 11.7 -899.4 -899418 5.4 HDGF CREB3L1 MLX AGO1 ZFP64 ARID4B SIN3A DMAP1 ZNF2 ZNF766 KLF16 CSNK1G2 ZNF555 SF3A2 BTBD2 CSNK1G2-AS1 C19orf35 ENSG00000267283 REXO1 LOC105372239
GH19G002490 1.9 FANTOM5 Ensembl ENCODE dbSUPER 9.9 -347.3 -347256 7.0 ATF1 CREB3L1 SIN3A ZNF207 ZNF143 FOS SMARCB1 PPARG ZNF592 MEF2D ZNF77 ZNF554 GADD45B ZNF555 THOP1 TMPRSS9 DOT1L GC19M002492 GC19P002492
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around ZNF555 on UCSC Golden Path with GeneCards custom track

Promoters for ZNF555 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000105948 66 2200 PKNOX1 ARID4B SIN3A DMAP1 FEZF1 ZNF2 YY1 SLC30A9 ZNF302 ZNF143

Transcription factor binding sites by QIAGEN in the ZNF555 gene promoter:

Genomic Location for ZNF555 Gene

2,841,435 bp from pter
2,860,484 bp from pter
19,050 bases
Plus strand

Genomic View for ZNF555 Gene

Genes around ZNF555 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF555 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF555 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF555 Gene

Proteins for ZNF555 Gene

  • Protein details for ZNF555 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Zinc finger protein 555
    Protein Accession:
    Secondary Accessions:
    • A8KA89
    • K7EQM2
    • Q8NA46
    • Q96MP1

    Protein attributes for ZNF555 Gene

    628 amino acids
    Molecular mass:
    73084 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ZNF555 Gene


neXtProt entry for ZNF555 Gene

Post-translational modifications for ZNF555 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF555 Gene

No data available for DME Specific Peptides for ZNF555 Gene

Domains & Families for ZNF555 Gene

Gene Families for ZNF555 Gene

Protein Domains for ZNF555 Gene

Suggested Antigen Peptide Sequences for ZNF555 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
genes like me logo Genes that share domains with ZNF555: view

Function for ZNF555 Gene

Molecular function for ZNF555 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Gene Ontology (GO) - Molecular Function for ZNF555 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
GO:0005515 protein binding IPI 25416956
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF555: view
genes like me logo Genes that share phenotypes with ZNF555: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF555 Gene

Localization for ZNF555 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF555 Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZNF555 gene
Compartment Confidence
nucleus 5
cytosol 2

Gene Ontology (GO) - Cellular Components for ZNF555 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular IEA --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF555: view

Pathways & Interactions for ZNF555 Gene

SuperPathways for ZNF555 Gene

SuperPathway Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF555: view

Pathways by source for ZNF555 Gene

2 Reactome pathways for ZNF555 Gene

Gene Ontology (GO) - Biological Process for ZNF555 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF555: view

No data available for SIGNOR curated interactions for ZNF555 Gene

Drugs & Compounds for ZNF555 Gene

No Compound Related Data Available

Transcripts for ZNF555 Gene

Unigene Clusters for ZNF555 Gene

Zinc finger protein 555:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF555 Gene

ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4a · 4b · 4c
SP2: -

Relevant External Links for ZNF555 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ZNF555 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ZNF555 Gene

Protein differential expression in normal tissues from HIPED for ZNF555 Gene

This gene is overexpressed in Synovial fluid (68.9).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for ZNF555 Gene

Protein tissue co-expression partners for ZNF555 Gene

NURSA nuclear receptor signaling pathways regulating expression of ZNF555 Gene:


SOURCE GeneReport for Unigene cluster for ZNF555 Gene:


Evidence on tissue expression from TISSUES for ZNF555 Gene

  • Intestine(4.1)
genes like me logo Genes that share expression patterns with ZNF555: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZNF555 Gene

Orthologs for ZNF555 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZNF555 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia ZNF555 34 35
  • 99.15 (n)
(Canis familiaris)
Mammalia ZNF555 34 35
  • 85.81 (n)
(Bos Taurus)
Mammalia ZNF555 34 35
  • 85.36 (n)
(Monodelphis domestica)
Mammalia -- 35
  • 53 (a)
-- 35
  • 49 (a)
-- 35
  • 47 (a)
-- 35
  • 45 (a)
(Mus musculus)
Mammalia Gm14391 35
  • 50 (a)
(Ornithorhynchus anatinus)
Mammalia -- 35
  • 47 (a)
(Anolis carolinensis)
Reptilia -- 35
  • 45 (a)
(Danio rerio)
Actinopterygii CR388132.2 35
  • 42 (a)
CT573234.2 35
  • 42 (a)
Species where no ortholog for ZNF555 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ZNF555 Gene

Gene Tree for ZNF555 (if available)
Gene Tree for ZNF555 (if available)

Paralogs for ZNF555 Gene

(481) SIMAP similar genes for ZNF555 Gene using alignment to 2 proteins: Pseudogenes for ZNF555 Gene

genes like me logo Genes that share paralogs with ZNF555: view

Variants for ZNF555 Gene

Sequence variations from dbSNP and Humsavar for ZNF555 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
rs1000217973 -- 2,849,236(+) CATCT(C/T)GGGGG intron-variant
rs1000291602 -- 2,849,025(+) ACACT(C/G)CAAAT intron-variant
rs1000318270 -- 2,843,256(+) CCTCC(G/T)GGGCT intron-variant
rs1000387075 -- 2,856,166(+) ATAAA(C/T)GTTAT utr-variant-3-prime
rs1000464593 -- 2,844,310(+) ATTGG(C/G)CAGGC intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF555 Gene

Variant ID Type Subtype PubMed ID
dgv6226n54 CNV loss 21841781
esv2670441 CNV deletion 23128226
esv27111 CNV loss 19812545
nsv1143407 CNV deletion 24896259
nsv482209 CNV loss 20164927
nsv509715 CNV insertion 20534489
nsv528638 CNV gain 19592680

Variation tolerance for ZNF555 Gene

Residual Variation Intolerance Score: 8.69% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.05; 21.46% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ZNF555 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF555 Gene

Disorders for ZNF555 Gene

Relevant External Links for ZNF555

Genetic Association Database (GAD)
Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for ZNF555 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF555 Gene

Publications for ZNF555 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 64
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 64
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3 64
  4. ZNF555 protein binds to transcriptional activator site of 4qA allele and ANT1: potential implication in Facioscapulohumeral dystrophy. (PMID: 26184877) Kim E. … Pirozhkova I. (Nucleic Acids Res. 2015) 3 64
  5. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3 64

Products for ZNF555 Gene

Sources for ZNF555 Gene

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