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Aliases for ZNF550 Gene

Aliases for ZNF550 Gene

  • Zinc Finger Protein 550 2 3

External Ids for ZNF550 Gene

Previous GeneCards Identifiers for ZNF550 Gene

  • GC19M062746
  • GC19M062747
  • GC19M058053
  • GC19M054370
  • GC19M058061

Summaries for ZNF550 Gene

GeneCards Summary for ZNF550 Gene

ZNF550 (Zinc Finger Protein 550) is a Protein Coding gene. Among its related pathways are Gene Expression and Gene Expression. An important paralog of this gene is ZNF460.

UniProtKB/Swiss-Prot for ZNF550 Gene

  • May be involved in transcriptional regulation

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF550 Gene

Genomics for ZNF550 Gene

Regulatory Elements for ZNF550 Gene

Genomic Location for ZNF550 Gene

Start:
57,535,257 bp from pter
End:
57,559,863 bp from pter
Size:
24,607 bases
Orientation:
Minus strand

Genomic View for ZNF550 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZNF550 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF550 Gene

Proteins for ZNF550 Gene

  • Protein details for ZNF550 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q7Z398-ZN550_HUMAN
    Recommended name:
    Zinc finger protein 550
    Protein Accession:
    Q7Z398
    Secondary Accessions:
    • B3KVF6
    • O43337
    • Q7Z6D7
    • Q8NE45

    Protein attributes for ZNF550 Gene

    Size:
    422 amino acids
    Molecular mass:
    48381 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAH34810.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=AAH53858.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305};

    Alternative splice isoforms for ZNF550 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZNF550 Gene

Proteomics data for ZNF550 Gene at MOPED

Post-translational modifications for ZNF550 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF550 Gene

No data available for DME Specific Peptides for ZNF550 Gene

Domains for ZNF550 Gene

Gene Families for ZNF550 Gene

HGNC:
  • ZNF :Zinc fingers, C2H2-type

Protein Domains for ZNF550 Gene

Suggested Antigen Peptide Sequences for ZNF550 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q7Z398

UniProtKB/Swiss-Prot:

ZN550_HUMAN :
  • Q7Z398
Domain:
  • Contains 1 KRAB domain.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 8 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF550: view

Function for ZNF550 Gene

Molecular function for ZNF550 Gene

UniProtKB/Swiss-Prot Function: May be involved in transcriptional regulation

Gene Ontology (GO) - Molecular Function for ZNF550 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding --
GO:0003677 DNA binding IEA --
GO:0005515 protein binding IPI 25416956
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF550: view
genes like me logo Genes that share phenotypes with ZNF550: view

Animal Model Products

CRISPR Products

No data available for Enzyme Numbers (IUBMB) , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for ZNF550 Gene

Localization for ZNF550 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF550 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF550 Gene COMPARTMENTS Subcellular localization image for ZNF550 gene
Compartment Confidence
nucleus 4
cytosol 2
cytoskeleton 1
mitochondrion 1

Gene Ontology (GO) - Cellular Components for ZNF550 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF550: view

Pathways for ZNF550 Gene

SuperPathways for ZNF550 Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF550: view

Pathways by source for ZNF550 Gene

2 Reactome pathways for ZNF550 Gene

Interacting Proteins for ZNF550 Gene

Gene Ontology (GO) - Biological Process for ZNF550 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF550: view

Transcripts for ZNF550 Gene

Unigene Clusters for ZNF550 Gene

Zinc finger protein 550:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZNF550

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF550 Gene

No ASD Table

Relevant External Links for ZNF550 Gene

GeneLoc Exon Structure for
ZNF550
ECgene alternative splicing isoforms for
ZNF550

Expression for ZNF550 Gene

mRNA expression in normal human tissues for ZNF550 Gene

SOURCE GeneReport for Unigene cluster for ZNF550 Gene Hs.180257

genes like me logo Genes that share expressions with ZNF550: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein expression and mRNA Expression by UniProt/SwissProt for ZNF550 Gene

Orthologs for ZNF550 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZNF550 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF550 35
  • 99.68 (n)
  • 99.53 (a)
ZNF550 36
  • 90 (a)
OneToOne
cow
(Bos Taurus)
Mammalia ZNF550 35
  • 78.97 (n)
  • 76.28 (a)
ZNF550 36
  • 38 (a)
OneToOne
dog
(Canis familiaris)
Mammalia ZNF550 35
  • 84.84 (n)
  • 81.9 (a)
ZNF550 36
  • 75 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia -- 36
  • 29 (a)
OneToMany
zebrafish
(Danio rerio)
Actinopterygii CU138542.3 36
  • 29 (a)
ManyToMany
si:dkey-7j22.3 36
  • 35 (a)
ManyToMany
Species with no ortholog for ZNF550:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ZNF550 Gene

ENSEMBL:
Gene Tree for ZNF550 (if available)
TreeFam:
Gene Tree for ZNF550 (if available)

Paralogs for ZNF550 Gene

Paralogs for ZNF550 Gene

Selected SIMAP similar genes for ZNF550 Gene using alignment to 3 proteins:

genes like me logo Genes that share paralogs with ZNF550: view

Variants for ZNF550 Gene

Sequence variations from dbSNP and Humsavar for ZNF550 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type MAF
rs1548475 -- 57,546,878(+) TTGCA(C/T)TCGAA utr-variant-3-prime, intron-variant
rs1548476 - 57,547,168(+) GCTGT(A/G)TGAGT missense, reference, intron-variant
rs2188922 -- 57,559,272(+) GGGGG(A/G)GAAGA intron-variant
rs2188923 -- 57,559,273(+) GGGGG(A/G)AAGAG intron-variant
rs2269816 -- 57,552,919(+) GTTGA(C/T)GCCCT intron-variant

Relevant External Links for ZNF550 Gene

HapMap Linkage Disequilibrium report
ZNF550

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for ZNF550 Gene

Disorders for ZNF550 Gene

No disorders were found for ZNF550 Gene.

No data available for UniProtKB/Swiss-Prot for ZNF550 Gene

Publications for ZNF550 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. The DNA sequence and biology of human chromosome 19. (PMID: 15057824) Grimwood J. … Lucas S.M. (Nature 2004) 3 4
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  5. Immunoaffinity profiling of tyrosine phosphorylation in cancer cells. (PMID: 15592455) Rush J. … Comb M.J. (Nat. Biotechnol. 2005) 3

Products for ZNF550 Gene

Sources for ZNF550 Gene

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