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Aliases for ZNF550 Gene

Aliases for ZNF550 Gene

  • Zinc Finger Protein 550 2 3 5

External Ids for ZNF550 Gene

Previous GeneCards Identifiers for ZNF550 Gene

  • GC19M062746
  • GC19M062747
  • GC19M058053
  • GC19M054370
  • GC19M058061

Summaries for ZNF550 Gene

GeneCards Summary for ZNF550 Gene

ZNF550 (Zinc Finger Protein 550) is a Protein Coding gene. Among its related pathways are Gene Expression. GO annotations related to this gene include nucleic acid binding. An important paralog of this gene is ZNF805.

UniProtKB/Swiss-Prot for ZNF550 Gene

  • May be involved in transcriptional regulation.

No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF550 Gene

Genomics for ZNF550 Gene

Regulatory Elements for ZNF550 Gene

Enhancers for ZNF550 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH19G058181 1.1 ENCODE 43.8 -621.6 -621590 2.5 HDGF PKNOX1 CREB3L1 ARNT AGO1 ARID4B SIN3A DMAP1 ZNF2 ZBTB7B ZNF134 ZNF549 ZNF606 ZNF773 ZNF17 ZNF418 ZNF550 ZNF417 ZNF256 ZNF543
GH19G056594 1 ENCODE 47.4 +966.2 966207 1.4 HDGF PKNOX1 ZNF133 ARID4B SIN3A FEZF1 YBX1 GLI4 ZNF48 YY1 ZNF17 ENSG00000269696 ZNF549 ZNF773 ZNF543 U2AF2 ZFP28 ZNF667 ZNF470 FIZ1
GH19G057809 1.7 FANTOM5 ENCODE dbSUPER 25.8 -251.6 -251571 7.2 CREB3L1 MLX ZFP64 DMAP1 FEZF1 YY1 SLC30A9 ZNF416 ZNF143 ZNF548 ZNF134 ZNF264 TRIM28 ZNF17 ZNF417 ZNF256 ZNF543 ZNF805 ZNF606 ZNF773
GH19G058553 1.4 ENCODE dbSUPER 19.5 -995.5 -995466 7.2 CREB3L1 AGO1 FEZF1 DMAP1 YY1 SLC30A9 ZNF143 SP3 NFYC ZFP41 ZNF606 ZNF417 TRIM28 MZF1-AS1 ZNF550 ZNF134 ZNF584 CENPBD1P1 ZNF776 ZNF551
GH19G057599 1.1 ENCODE 23.6 -38.4 -38391 1.5 PKNOX1 CREB3L1 ARID4B SIN3A DMAP1 YY1 ZNF207 ZNF143 SP3 ZHX2 ZNF606 ZNF549 ZNF417 ZNF418 LOC100128398 ZNF17 ZNF773 LOC105372482 ZNF211 ENSG00000268201
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around ZNF550 on UCSC Golden Path with GeneCards custom track

Genomic Location for ZNF550 Gene

Chromosome:
19
Start:
57,535,257 bp from pter
End:
57,561,647 bp from pter
Size:
26,391 bases
Orientation:
Minus strand

Genomic View for ZNF550 Gene

Genes around ZNF550 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF550 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF550 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF550 Gene

Proteins for ZNF550 Gene

  • Protein details for ZNF550 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q7Z398-ZN550_HUMAN
    Recommended name:
    Zinc finger protein 550
    Protein Accession:
    Q7Z398
    Secondary Accessions:
    • B3KVF6
    • O43337
    • Q7Z6D7
    • Q8NE45

    Protein attributes for ZNF550 Gene

    Size:
    422 amino acids
    Molecular mass:
    48381 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAH34810.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=AAH53858.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305};

    Alternative splice isoforms for ZNF550 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZNF550 Gene

Post-translational modifications for ZNF550 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for ZNF550 Gene

Domains & Families for ZNF550 Gene

Gene Families for ZNF550 Gene

Protein Domains for ZNF550 Gene

Suggested Antigen Peptide Sequences for ZNF550 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q7Z398

UniProtKB/Swiss-Prot:

ZN550_HUMAN :
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
genes like me logo Genes that share domains with ZNF550: view

Function for ZNF550 Gene

Molecular function for ZNF550 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Gene Ontology (GO) - Molecular Function for ZNF550 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
GO:0005515 protein binding IPI 25416956
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF550: view
genes like me logo Genes that share phenotypes with ZNF550: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF550 Gene

Localization for ZNF550 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF550 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZNF550 gene
Compartment Confidence
nucleus 5
cytosol 2

Gene Ontology (GO) - Cellular Components for ZNF550 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular IEA --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF550: view

Pathways & Interactions for ZNF550 Gene

SuperPathways for ZNF550 Gene

SuperPathway Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF550: view

Pathways by source for ZNF550 Gene

2 Reactome pathways for ZNF550 Gene

Gene Ontology (GO) - Biological Process for ZNF550 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF550: view

No data available for SIGNOR curated interactions for ZNF550 Gene

Drugs & Compounds for ZNF550 Gene

No Compound Related Data Available

Transcripts for ZNF550 Gene

Unigene Clusters for ZNF550 Gene

Zinc finger protein 550:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF550 Gene

No ASD Table

Relevant External Links for ZNF550 Gene

GeneLoc Exon Structure for
ZNF550
ECgene alternative splicing isoforms for
ZNF550

Expression for ZNF550 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ZNF550 Gene

NURSA nuclear receptor signaling pathways regulating expression of ZNF550 Gene:

ZNF550

SOURCE GeneReport for Unigene cluster for ZNF550 Gene:

Hs.180257

Evidence on tissue expression from TISSUES for ZNF550 Gene

  • Nervous system(4.1)
genes like me logo Genes that share expression patterns with ZNF550: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZNF550 Gene

Orthologs for ZNF550 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZNF550 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF550 34 35
  • 99.68 (n)
dog
(Canis familiaris)
Mammalia ZNF550 34 35
  • 84.84 (n)
cow
(Bos Taurus)
Mammalia ZNF550 34 35
  • 78.97 (n)
lizard
(Anolis carolinensis)
Reptilia -- 35
  • 29 (a)
OneToMany
zebrafish
(Danio rerio)
Actinopterygii si:dkey-7j22.3 35
  • 35 (a)
ManyToMany
CU138542.3 35
  • 29 (a)
ManyToMany
Species where no ortholog for ZNF550 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ZNF550 Gene

ENSEMBL:
Gene Tree for ZNF550 (if available)
TreeFam:
Gene Tree for ZNF550 (if available)

Paralogs for ZNF550 Gene

Paralogs for ZNF550 Gene

(517) SIMAP similar genes for ZNF550 Gene using alignment to 3 proteins:

genes like me logo Genes that share paralogs with ZNF550: view

Variants for ZNF550 Gene

Sequence variations from dbSNP and Humsavar for ZNF550 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
rs1000003470 -- 57,553,769(+) TTGGG(A/G)ATGCG intron-variant
rs1000183925 -- 57,545,838(+) TAAAA(C/T)CTTGT intron-variant
rs1000231384 -- 57,545,537(+) TAAAG(-/AC)ACAAC intron-variant
rs1000239305 -- 57,553,555(+) AGGGA(A/C/T)TACAG intron-variant
rs1000344498 -- 57,551,556(+) AGCTA(C/T)GTGGT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF550 Gene

Variant ID Type Subtype PubMed ID
esv3644905 CNV loss 21293372

Variation tolerance for ZNF550 Gene

Residual Variation Intolerance Score: 92.9% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.60; 30.76% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ZNF550 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ZNF550

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF550 Gene

Disorders for ZNF550 Gene

Relevant External Links for ZNF550

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ZNF550

No disorders were found for ZNF550 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF550 Gene

Publications for ZNF550 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 64
  2. The DNA sequence and biology of human chromosome 19. (PMID: 15057824) Grimwood J. … Lucas S.M. (Nature 2004) 3 4 64
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 64
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3 64
  5. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3 64

Products for ZNF550 Gene

Sources for ZNF550 Gene

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