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Aliases for ZNF550 Gene

Aliases for ZNF550 Gene

  • Zinc Finger Protein 550 2 3 5

External Ids for ZNF550 Gene

Previous GeneCards Identifiers for ZNF550 Gene

  • GC19M062746
  • GC19M062747
  • GC19M058053
  • GC19M054370
  • GC19M058061

Summaries for ZNF550 Gene

GeneCards Summary for ZNF550 Gene

ZNF550 (Zinc Finger Protein 550) is a Protein Coding gene. Among its related pathways are Gene Expression. GO annotations related to this gene include nucleic acid binding. An important paralog of this gene is ZNF460.

UniProtKB/Swiss-Prot for ZNF550 Gene

  • May be involved in transcriptional regulation.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF550 Gene

Genomics for ZNF550 Gene

Regulatory Elements for ZNF550 Gene

Genomic Location for ZNF550 Gene

57,535,257 bp from pter
57,561,647 bp from pter
26,391 bases
Minus strand

Genomic View for ZNF550 Gene

Genes around ZNF550 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF550 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF550 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF550 Gene

Proteins for ZNF550 Gene

  • Protein details for ZNF550 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Zinc finger protein 550
    Protein Accession:
    Secondary Accessions:
    • B3KVF6
    • O43337
    • Q7Z6D7
    • Q8NE45

    Protein attributes for ZNF550 Gene

    422 amino acids
    Molecular mass:
    48381 Da
    Quaternary structure:
    No Data Available
    • Sequence=AAH34810.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=AAH53858.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305};

    Alternative splice isoforms for ZNF550 Gene


neXtProt entry for ZNF550 Gene

Proteomics data for ZNF550 Gene at MOPED

Post-translational modifications for ZNF550 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Antibody Products

No data available for DME Specific Peptides for ZNF550 Gene

Domains & Families for ZNF550 Gene

Gene Families for ZNF550 Gene

Protein Domains for ZNF550 Gene

Suggested Antigen Peptide Sequences for ZNF550 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Contains 1 KRAB domain.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 8 C2H2-type zinc fingers.
  • Contains 1 KRAB domain.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 8 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF550: view

Function for ZNF550 Gene

Molecular function for ZNF550 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.
genes like me logo Genes that share phenotypes with ZNF550: view

Animal Model Products

CRISPR Products

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF550 Gene

Localization for ZNF550 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF550 Gene

Subcellular locations from

Jensen Localization Image for ZNF550 Gene COMPARTMENTS Subcellular localization image for ZNF550 gene
Compartment Confidence
nucleus 5
cytosol 2

No data available for Gene Ontology (GO) - Cellular Components for ZNF550 Gene

Pathways & Interactions for ZNF550 Gene

SuperPathways for ZNF550 Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF550: view

Pathways by source for ZNF550 Gene

2 Reactome pathways for ZNF550 Gene

Interacting Proteins for ZNF550 Gene

Gene Ontology (GO) - Biological Process for ZNF550 Gene


No data available for SIGNOR curated interactions for ZNF550 Gene

Drugs & Compounds for ZNF550 Gene

No Compound Related Data Available

Transcripts for ZNF550 Gene

Unigene Clusters for ZNF550 Gene

Zinc finger protein 550:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF550 Gene

No ASD Table

Relevant External Links for ZNF550 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ZNF550 Gene

mRNA expression in normal human tissues for ZNF550 Gene

SOURCE GeneReport for Unigene cluster for ZNF550 Gene Hs.180257

genes like me logo Genes that share expression patterns with ZNF550: view

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for ZNF550 Gene

Orthologs for ZNF550 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZNF550 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia ZNF550 35
  • 78.97 (n)
  • 76.28 (a)
ZNF550 36
  • 38 (a)
(Canis familiaris)
Mammalia ZNF550 35
  • 84.84 (n)
  • 81.9 (a)
ZNF550 36
  • 75 (a)
(Pan troglodytes)
Mammalia ZNF550 35
  • 99.68 (n)
  • 99.53 (a)
ZNF550 36
  • 90 (a)
(Anolis carolinensis)
Reptilia -- 36
  • 29 (a)
(Danio rerio)
Actinopterygii CU138542.3 36
  • 29 (a)
si:dkey-7j22.3 36
  • 35 (a)
Species with no ortholog for ZNF550:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ZNF550 Gene

Gene Tree for ZNF550 (if available)
Gene Tree for ZNF550 (if available)

Paralogs for ZNF550 Gene

Paralogs for ZNF550 Gene

(517) SIMAP similar genes for ZNF550 Gene using alignment to 3 proteins:

genes like me logo Genes that share paralogs with ZNF550: view

Variants for ZNF550 Gene

Sequence variations from dbSNP and Humsavar for ZNF550 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
rs1548476 - 57,547,168(+) GCTGT(A/G)TGAGT intron-variant, reference, missense
rs1548475 -- 57,546,878(+) TTGCA(C/T)TCGAA intron-variant, utr-variant-3-prime
rs2285668 -- 57,550,906(+) AGTTA(C/T)AGGGT intron-variant
rs2188922 -- 57,559,272(+) GGGGG(A/G)GAAGA intron-variant
rs2188923 -- 57,559,273(+) GGGGG(A/G)AAGAG intron-variant

Variation tolerance for ZNF550 Gene

Residual Variation Intolerance Score: 92.9% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.60; 30.76% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ZNF550 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for ZNF550 Gene

Disorders for ZNF550 Gene

Relevant External Links for ZNF550

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for ZNF550 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF550 Gene

Publications for ZNF550 Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 67
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  3. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3
  4. Immunoaffinity profiling of tyrosine phosphorylation in cancer cells. (PMID: 15592455) Rush J. … Comb M.J. (Nat. Biotechnol. 2005) 3
  5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3

Products for ZNF550 Gene

Sources for ZNF550 Gene

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