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Aliases for ZNF548 Gene

Aliases for ZNF548 Gene

  • Zinc Finger Protein 548 2 3

External Ids for ZNF548 Gene

Previous GeneCards Identifiers for ZNF548 Gene

  • GC19P062594
  • GC19P062595
  • GC19P057902
  • GC19P054213

Summaries for ZNF548 Gene

GeneCards Summary for ZNF548 Gene

ZNF548 (Zinc Finger Protein 548) is a Protein Coding gene. Among its related pathways are Gene Expression and Gene Expression. An important paralog of this gene is ZNF17.

UniProtKB/Swiss-Prot for ZNF548 Gene

  • May be involved in transcriptional regulation

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF548 Gene

Genomics for ZNF548 Gene

Regulatory Elements for ZNF548 Gene

Transcription factor binding sites by QIAGEN in the ZNF548 gene promoter:

Genomic Location for ZNF548 Gene

Start:
57,389,850 bp from pter
End:
57,402,551 bp from pter
Size:
12,702 bases
Orientation:
Plus strand

Genomic View for ZNF548 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZNF548 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF548 Gene

Proteins for ZNF548 Gene

  • Protein details for ZNF548 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8NEK5-ZN548_HUMAN
    Recommended name:
    Zinc finger protein 548
    Protein Accession:
    Q8NEK5
    Secondary Accessions:
    • Q96M05

    Protein attributes for ZNF548 Gene

    Size:
    533 amino acids
    Molecular mass:
    62728 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ZNF548 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZNF548 Gene

Proteomics data for ZNF548 Gene at MOPED

Post-translational modifications for ZNF548 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for ZNF548 Gene

Domains for ZNF548 Gene

Gene Families for ZNF548 Gene

HGNC:
  • ZNF :Zinc fingers, C2H2-type

Protein Domains for ZNF548 Gene

Suggested Antigen Peptide Sequences for ZNF548 Gene

Graphical View of Domain Structure for InterPro Entry

Q8NEK5

UniProtKB/Swiss-Prot:

ZN548_HUMAN :
  • Q8NEK5
Domain:
  • Contains 1 KRAB domain.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 11 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF548: view

Function for ZNF548 Gene

Molecular function for ZNF548 Gene

UniProtKB/Swiss-Prot Function: May be involved in transcriptional regulation

Gene Ontology (GO) - Molecular Function for ZNF548 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding --
GO:0003677 DNA binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF548: view

miRNA for ZNF548 Gene

miRTarBase miRNAs that target ZNF548

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for ZNF548 Gene

Localization for ZNF548 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF548 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF548 Gene COMPARTMENTS Subcellular localization image for ZNF548 gene
Compartment Confidence
nucleus 4

Gene Ontology (GO) - Cellular Components for ZNF548 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF548: view

Pathways for ZNF548 Gene

SuperPathways for ZNF548 Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF548: view

Pathways by source for ZNF548 Gene

2 Reactome pathways for ZNF548 Gene

Interacting Proteins for ZNF548 Gene

Gene Ontology (GO) - Biological Process for ZNF548 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF548: view

Transcripts for ZNF548 Gene

Unigene Clusters for ZNF548 Gene

Zinc finger protein 548:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF548 Gene

ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3a · 3b ^ 4a · 4b ^ 5a · 5b ^ 6a · 6b ^ 7a · 7b · 7c · 7d · 7e
SP1: - - - - - -
SP2: - - - - -
SP3: - -
SP4: - - -
SP5: - -
SP6: - - - - - - - -
SP7: - - - - - -
SP8:

Relevant External Links for ZNF548 Gene

GeneLoc Exon Structure for
ZNF548
ECgene alternative splicing isoforms for
ZNF548

Expression for ZNF548 Gene

mRNA expression in normal human tissues for ZNF548 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for ZNF548 Gene

SOURCE GeneReport for Unigene cluster for ZNF548 Gene Hs.126905

genes like me logo Genes that share expressions with ZNF548: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ZNF548 Gene

Orthologs for ZNF548 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF548 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF548 35
  • 99.39 (n)
  • 99.27 (a)
ZNF548 36
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia ZNF548 35
  • 78.33 (n)
  • 67.5 (a)
ZNF548 36
  • 63 (a)
OneToOne
dog
(Canis familiaris)
Mammalia ZNF548 35
  • 81.3 (n)
  • 71.4 (a)
ZNF548 36
  • 64 (a)
OneToOne
Species with no ortholog for ZNF548:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF548 Gene

ENSEMBL:
Gene Tree for ZNF548 (if available)
TreeFam:
Gene Tree for ZNF548 (if available)

Paralogs for ZNF548 Gene

Selected SIMAP similar genes for ZNF548 Gene using alignment to 11 proteins:

genes like me logo Genes that share paralogs with ZNF548: view

Variants for ZNF548 Gene

Sequence variations from dbSNP and Humsavar for ZNF548 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type MAF
rs1808188 -- 57,395,034(+) GGAGA(C/T)GTCCA intron-variant
rs2020178 -- 57,395,012(+) TCCTG(A/G)TGGAG intron-variant
rs4801478 - 57,398,504(+) TTACA(A/G)CTTCA missense, reference
rs4801479 -- 57,402,462(+) TTACT(C/G)TGTTT utr-variant-3-prime
rs7246889 -- 57,388,303(+) TTCTG(G/T)TTTTT upstream-variant-2KB

Relevant External Links for ZNF548 Gene

HapMap Linkage Disequilibrium report
ZNF548

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for ZNF548 Gene

Disorders for ZNF548 Gene

No disorders were found for ZNF548 Gene.

No data available for UniProtKB/Swiss-Prot for ZNF548 Gene

Publications for ZNF548 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  4. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PMID: 21890473) Wagner S.A. … Choudhary C. (Mol. Cell Proteomics 2011) 3
  5. The DNA sequence and biology of human chromosome 19. (PMID: 15057824) Grimwood J. … Lucas S.M. (Nature 2004) 4

Products for ZNF548 Gene

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat
  • QIAGEN qRT-PCR Assays for microRNAs that regulate ZNF548
    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat
    • Predesigned siRNA for gene silencing in human,mouse,rat for ZNF548
    • Block miRNA regulation of ZNF548 using miScript Target Protectors

    Sources for ZNF548 Gene

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