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Aliases for ZNF548 Gene

Aliases for ZNF548 Gene

  • Zinc Finger Protein 548 2 3 5

External Ids for ZNF548 Gene

Previous GeneCards Identifiers for ZNF548 Gene

  • GC19P062594
  • GC19P062595
  • GC19P057902
  • GC19P054213

Summaries for ZNF548 Gene

GeneCards Summary for ZNF548 Gene

ZNF548 (Zinc Finger Protein 548) is a Protein Coding gene. Among its related pathways are Gene Expression. GO annotations related to this gene include nucleic acid binding. An important paralog of this gene is ZNF17.

UniProtKB/Swiss-Prot for ZNF548 Gene

  • May be involved in transcriptional regulation.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF548 Gene

Genomics for ZNF548 Gene

Regulatory Elements for ZNF548 Gene

Enhancers for ZNF548 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around ZNF548 on UCSC Golden Path with GeneCards custom track

Promoters for ZNF548 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around ZNF548 on UCSC Golden Path with GeneCards custom track

Transcription factor binding sites by QIAGEN in the ZNF548 gene promoter:

Genomic Location for ZNF548 Gene

57,389,850 bp from pter
57,402,992 bp from pter
13,143 bases
Plus strand

Genomic View for ZNF548 Gene

Genes around ZNF548 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF548 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF548 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF548 Gene

Proteins for ZNF548 Gene

  • Protein details for ZNF548 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Zinc finger protein 548
    Protein Accession:
    Secondary Accessions:
    • Q96M05

    Protein attributes for ZNF548 Gene

    533 amino acids
    Molecular mass:
    62728 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ZNF548 Gene


neXtProt entry for ZNF548 Gene

Proteomics data for ZNF548 Gene at MOPED

Post-translational modifications for ZNF548 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for ZNF548 Gene

Domains & Families for ZNF548 Gene

Gene Families for ZNF548 Gene

Protein Domains for ZNF548 Gene

Suggested Antigen Peptide Sequences for ZNF548 Gene

Graphical View of Domain Structure for InterPro Entry



  • Contains 1 KRAB domain.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 11 C2H2-type zinc fingers.
  • Contains 1 KRAB domain.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 11 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF548: view

Function for ZNF548 Gene

Molecular function for ZNF548 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Gene Ontology (GO) - Molecular Function for ZNF548 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding IEA --
genes like me logo Genes that share ontologies with ZNF548: view

Phenotypes for ZNF548 Gene

GenomeRNAi human phenotypes for ZNF548:
genes like me logo Genes that share phenotypes with ZNF548: view

Animal Model Products

CRISPR Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF548 Gene

Localization for ZNF548 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF548 Gene

Subcellular locations from

Jensen Localization Image for ZNF548 Gene COMPARTMENTS Subcellular localization image for ZNF548 gene
Compartment Confidence
nucleus 5

No data available for Gene Ontology (GO) - Cellular Components for ZNF548 Gene

Pathways & Interactions for ZNF548 Gene

SuperPathways for ZNF548 Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF548: view

Pathways by source for ZNF548 Gene

2 Reactome pathways for ZNF548 Gene

Interacting Proteins for ZNF548 Gene

Gene Ontology (GO) - Biological Process for ZNF548 Gene


No data available for SIGNOR curated interactions for ZNF548 Gene

Drugs & Compounds for ZNF548 Gene

No Compound Related Data Available

Transcripts for ZNF548 Gene

Unigene Clusters for ZNF548 Gene

Zinc finger protein 548:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF548 Gene

ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3a · 3b ^ 4a · 4b ^ 5a · 5b ^ 6a · 6b ^ 7a · 7b · 7c · 7d · 7e
SP1: - - - - - -
SP2: - - - - -
SP3: - -
SP4: - - -
SP5: - -
SP6: - - - - - - - -
SP7: - - - - - -

Relevant External Links for ZNF548 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ZNF548 Gene

mRNA expression in normal human tissues for ZNF548 Gene

Protein differential expression in normal tissues from HIPED for ZNF548 Gene

This gene is overexpressed in Platelet (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for ZNF548 Gene

SOURCE GeneReport for Unigene cluster for ZNF548 Gene Hs.126905

genes like me logo Genes that share expression patterns with ZNF548: view

Protein tissue co-expression partners for ZNF548 Gene

- Elite partner

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ZNF548 Gene

Orthologs for ZNF548 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF548 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia ZNF548 35
  • 78.33 (n)
  • 67.5 (a)
ZNF548 36
  • 63 (a)
(Canis familiaris)
Mammalia ZNF548 35
  • 81.3 (n)
  • 71.4 (a)
ZNF548 36
  • 64 (a)
(Pan troglodytes)
Mammalia ZNF548 35
  • 99.39 (n)
  • 99.27 (a)
ZNF548 36
  • 99 (a)
Species with no ortholog for ZNF548:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF548 Gene

Gene Tree for ZNF548 (if available)
Gene Tree for ZNF548 (if available)

Paralogs for ZNF548 Gene

genes like me logo Genes that share paralogs with ZNF548: view

Variants for ZNF548 Gene

Sequence variations from dbSNP and Humsavar for ZNF548 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
rs17856896 - 57,398,459(+) AGGAG(A/G/T)CACCT reference, missense
rs4801478 - 57,398,504(+) TTACA(A/G)CTTCA reference, missense
rs7256963 -- 57,392,078(+) acagg(C/T)gtgag intron-variant
rs7256988 -- 57,392,135(+) ttgtt(G/T)ttttg intron-variant
rs12978811 -- 57,400,966(+) tgatt(A/G)atgat utr-variant-3-prime

Variation tolerance for ZNF548 Gene

Residual Variation Intolerance Score: 59.3% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 3.04; 50.34% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Relevant External Links for ZNF548 Gene

Disorders for ZNF548 Gene

Relevant External Links for ZNF548

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for ZNF548 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF548 Gene

Publications for ZNF548 Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 67
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3
  4. Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions. (PMID: 15342556) Suzuki Y. … Sugano S. (Genome Res. 2004) 3

Products for ZNF548 Gene

Sources for ZNF548 Gene