ZNF544 Gene
protein-coding GIFtS: 47
GCID: GC19P058740
|
|
zinc finger protein 544
| |
Aliases
for ZNF544 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Zinc Finger Protein 5441 2 | | AF0205911 |
Export aliases for ZNF544 gene to outside databasesPrevious GC identifers: GC00U914382 GC19P063061 GC19P063433 GC19P055050 |
Summaries
for ZNF544 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
UniProtKB/Swiss-Prot: ZN544_HUMAN, Q6NX49Function: May be involved in transcriptional regulation
|
Genomic Views
for ZNF544 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000019.9 NC_018930.1 NT_011109.16
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the ZNF544 gene promoter:
CRE-BP1 CREB NF-AT4 NF-AT2 NF-kappaB2 ATF-2 NF-AT3 NF-kappaB NF-kappaB1 RSRFC4
Other transcription factors
Search SABiosciences Chromatin IP Primers for ZNF544
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZNF544 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 19q13.43 Ensembl cytogenetic band: 19q13.43 HGNC cytogenetic band: 19q13.43ZNF544 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 19 GeneLoc Exon Structure GeneLoc location for GC19P058740: view genomic region
(about GC identifiers)
Start:
|
58,740,070 bp from pter |
End:
|
58,775,010 bp from pter |
Size:
|
34,941 bases |
Orientation:
|
plus strand |
|
Proteins
for ZNF544 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: ZN544_HUMAN, Q6NX49 (See
protein sequence)Recommended Name: Zinc finger protein 544 Size: 715 amino acids; 81742 Da
Subcellular location: Nucleus (Potential)
Secondary accessions: A8K6J1 Q9UEX4Explore the universe of human proteins at neXtProt for ZNF544: NX_Q6NX49
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q6NX49
ZNF544 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_055295.2
ENSEMBL proteins: ENSP00000269829 ENSP00000394341 ENSP00000329320 Reactome Protein details: Q6NX49
Human Recombinant Protein Products:
Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table
ZNF544 for ontologies About GeneDecksing
ZNF544 Antibody Products:
Assay Products for ZNF544: |
Protein
Domains /
Families
for ZNF544 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ZNF544 for domains About GeneDecksing
4 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q6NX49ProtoNet protein and cluster: Q6NX49 1 Blocks protein family: IPB001909 KRAB box
UniProtKB/Swiss-Prot: ZN544_HUMAN, Q6NX49Similarity: Belongs to the krueppel C2H2-type zinc-finger protein familySimilarity: Contains 13 C2H2-type zinc fingersSimilarity: Contains 1 KRAB domain |
Function
for ZNF544 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: ZN544_HUMAN, Q6NX49Function: May be involved in transcriptional regulation
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF544
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF544
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: ZNF544 (NM_014480) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ZNF544 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF544 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF544 |
Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table
ZNF544 for ontologies About GeneDecksing
|
Pathways & Interactions
for ZNF544 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Generic Transcription Pathway | |
Pathway sources
See GeneCards unified pathways
Show all pathways
2 
Reactome Pathways for ZNF544
ZNF544 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ZNF544
1 Interacting protein for ZNF544 (Q6NX493) via UniProtKB, MINT, STRING, and/or I2DAbout this table
Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006351 | transcription, DNA-dependent |
IEA | -- | | GO:0006355 | regulation of transcription, DNA-dependent |
IEA | -- |
ZNF544 for ontologies About GeneDecksing
|
Drugs & Compounds
for ZNF544 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for ZNF544
Search CenterWatch for drugs/clinical trials and news about ZNF544 / ZN544
|
Transcripts
for ZNF544 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for ZNF544 gene: NM_014480.2 Unigene Cluster for ZNF544: Zinc finger protein 544 Hs.438994 [show with all ESTs]Unigene Representative Sequence: AK2260803 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000269829(uc010eun.1 uc010yhw.1 uc010euo.3 uc010yhx.2 uc010yhy.2 uc002qrt.4 uc002qru.4)
ENST00000415203 ENST00000333581(uc002qrv.3)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF544
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF544
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: ZNF544 (NM_014480) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ZNF544 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF544 |
Additional cDNA sequence: AF020591.1 AF024692.1 AK226080.1 AK290297.1 AK291656.1 AK296846.1 AK301650.1 AK316446.1 AL833618.1 BC018980.1 BC042177.1 BC067271.1 24/27 DOTS entries (see all 27): DT.100790588 DT.95270405 DT.121495959 DT.100719564 DT.121496013 DT.97842675 DT.121495965 DT.95270403 DT.121495917 DT.40126218 DT.86846050 DT.92023018 DT.100659309 DT.100790587 DT.101964588 DT.121495984 DT.121495986 DT.100790586 DT.112822 DT.121495912 DT.121495926 DT.121495941 DT.121496022 DT.91962397 24/146 AceView cDNA sequences (see all 146): CR597557 BQ961408 BC067271 AI280139 AA706475 BE391947 BU147513 AL833618 CB140664 BM665516 BC018980 BM713737 T60903 AA336185 BI258819 AF024692 AI420720 CB134436 BF528232 BQ330577 BC042177 BI711059 AL044289 BE466962
GeneLoc Exon Structure
|
Expression
for ZNF544 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ZNF544 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TGCATCAGAA
About this image
See ZNF544 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for ZNF544
SOURCE GeneReport for Unigene cluster: Hs.438994
SABiosciences Custom PCR Arrays for ZNF544
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZNF544
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat ZNF544 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZNF544 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZNF544 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF544 |
Orthologs
for ZNF544 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for ZNF544 gene from 2/8 species (see all 8) About this table
Species with no ortholog for ZNF544
ENSEMBL Gene Tree for ZNF544 (if available)
TreeFam Gene Tree for ZNF544 (if available) |
Paralogs
for ZNF544 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for ZNF544 gene
- ZNF1802 ZNF3292 ZNF102 ZNF6062
18/559 SIMAP similar genes for ZNF544 using alignment to 9 protein entries: ZN544_HUMAN (see all proteins)
(see all similar genes):AVGR4 kr-znf3 ZNF56 HZF36 ZNF78L1 DKFZp686H10254
ZNF774 ZNF818P ZSCAN21 DKFZp434J0650 DKFZp666C237 DKFZp666M039
ZNF146 ZNF32 ZNF696 HZF30 ZNF22 zf30
ZNF544 for paralogs About GeneDecksing
|
Genomic Variants
for ZNF544 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 19 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for ZNF544 (58740070 - 58775010 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 2 variations for ZNF544
2 Indels: 45810 26362
Human Gene Mutation Database (HGMD): ZNF544
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ZNF544 |
|
Disorders
/ Diseases
for ZNF544 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
ZNF544 for disorders About GeneDecksing
1  disease for ZNF544: About MalaCardsattention deficit hyperactivity disorder
Export disorders for ZNF544 gene to outside databases
|
Publications
for ZNF544 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ZNF544 gene integrated from 9 sources:
(articles sorted by number of sources associating them with ZNF544) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Genome-wide association scan of quantitative traits for attention deficit hyperactivity disorder identifies novel associations and confirms candidate gene associations. (PubMed id 18821565)1 Lasky-Su J....Faraone S.V. (2008)
- Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)1 Barbe L....Andersson-Svahn H. (2008)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)2 Ota T.... Sugano S. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
- Hepatitis C virus core protein interacts with 14-3-3 protein and activates the kinase Raf-1. (PubMed id )2 Aoki H.... Hino O. (2000)
|
External Searches for ZNF544 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing ZNF544 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing ZNF544 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing ZNF544 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for ZNF544 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for ZNF544 gene:
Search GeneIP for patents involving ZNF544
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for ZNF544 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for ZNF544 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ZNF544 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZNF544 | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for ZNF544 | | OriGene 3'-UTR Clone for ZNF544 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF544 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF544 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for ZNF544 | | OriGene Custom Protein Services for ZNF544 | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ZNF544 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ZNF544 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZNF544 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ZNF544 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZNF544 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZNF544 |
| |
 |  |  |  | |
| | | | Search Tocris compounds for ZNF544 |
| |  |  |  |  | | | | |
 |
 |
 |
 | | | ZNF544 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF544 |
|  |  |  | | | | Search ThermoFisher Antibodies for ZNF544 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF544 |
|
|
|
|
