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Aliases for ZNF544 Gene

Aliases for ZNF544 Gene

  • Zinc Finger Protein 544 2 3 5
  • Zinc Finger Protein AF020591 2

External Ids for ZNF544 Gene

Previous GeneCards Identifiers for ZNF544 Gene

  • GC00U914382
  • GC19P063061
  • GC19P063433
  • GC19P058740
  • GC19P055050

Summaries for ZNF544 Gene

GeneCards Summary for ZNF544 Gene

ZNF544 (Zinc Finger Protein 544) is a Protein Coding gene. Among its related pathways are Gene Expression. GO annotations related to this gene include nucleic acid binding and transcription factor activity, sequence-specific DNA binding. An important paralog of this gene is ZNF180.

UniProtKB/Swiss-Prot for ZNF544 Gene

  • May be involved in transcriptional regulation.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF544 Gene

Genomics for ZNF544 Gene

Regulatory Elements for ZNF544 Gene

Enhancers for ZNF544 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
- Elite enhancer/Elite enhancer-gene association

Enhancers around ZNF544 on UCSC Golden Path with GeneCards custom track

Promoters for ZNF544 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

Genomic Location for ZNF544 Gene

Chromosome:
19
Start:
58,227,783 bp from pter
End:
58,277,495 bp from pter
Size:
49,713 bases
Orientation:
Plus strand

Genomic View for ZNF544 Gene

Genes around ZNF544 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF544 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF544 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF544 Gene

Proteins for ZNF544 Gene

  • Protein details for ZNF544 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6NX49-ZN544_HUMAN
    Recommended name:
    Zinc finger protein 544
    Protein Accession:
    Q6NX49
    Secondary Accessions:
    • A8K6J1
    • Q9UEX4

    Protein attributes for ZNF544 Gene

    Size:
    715 amino acids
    Molecular mass:
    81742 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZNF544 Gene

Post-translational modifications for ZNF544 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for ZNF544 Gene

Domains & Families for ZNF544 Gene

Gene Families for ZNF544 Gene

Protein Domains for ZNF544 Gene

Suggested Antigen Peptide Sequences for ZNF544 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q6NX49

UniProtKB/Swiss-Prot:

ZN544_HUMAN :
  • Contains 1 KRAB domain.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 13 C2H2-type zinc fingers.
Domain:
  • Contains 1 KRAB domain.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 13 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF544: view

Function for ZNF544 Gene

Molecular function for ZNF544 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Gene Ontology (GO) - Molecular Function for ZNF544 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
GO:0003700 transcription factor activity, sequence-specific DNA binding IBA --
GO:0005515 protein binding IPI 25416956
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF544: view

Phenotypes for ZNF544 Gene

genes like me logo Genes that share phenotypes with ZNF544: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF544 Gene

Localization for ZNF544 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF544 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF544 Gene COMPARTMENTS Subcellular localization image for ZNF544 gene
Compartment Confidence
nucleus 5
cytosol 2

Gene Ontology (GO) - Cellular Components for ZNF544 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF544: view

Pathways & Interactions for ZNF544 Gene

SuperPathways for ZNF544 Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF544: view

Pathways by source for ZNF544 Gene

2 Reactome pathways for ZNF544 Gene

Gene Ontology (GO) - Biological Process for ZNF544 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IBA --
genes like me logo Genes that share ontologies with ZNF544: view

No data available for SIGNOR curated interactions for ZNF544 Gene

Drugs & Compounds for ZNF544 Gene

No Compound Related Data Available

Transcripts for ZNF544 Gene

Unigene Clusters for ZNF544 Gene

Zinc finger protein 544:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF544 Gene

No ASD Table

Relevant External Links for ZNF544 Gene

GeneLoc Exon Structure for
ZNF544
ECgene alternative splicing isoforms for
ZNF544

Expression for ZNF544 Gene

mRNA expression in normal human tissues for ZNF544 Gene

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for ZNF544 Gene



NURSA nuclear receptor signaling pathways regulating expression of ZNF544 Gene:

ZNF544

SOURCE GeneReport for Unigene cluster for ZNF544 Gene:

Hs.438994
genes like me logo Genes that share expression patterns with ZNF544: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for ZNF544 Gene

Orthologs for ZNF544 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZNF544 Gene

Organism Taxonomy Gene Similarity Type Details
dog
(Canis familiaris)
Mammalia ZNF544 34
  • 73.03 (n)
  • 61.06 (a)
-- 35
  • 47 (a)
ManyToMany
chimpanzee
(Pan troglodytes)
Mammalia ZNF544 34
  • 99.39 (n)
  • 98.87 (a)
ZNF544 35
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia -- 35
  • 42 (a)
ManyToMany
oppossum
(Monodelphis domestica)
Mammalia -- 35
  • 47 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 35
  • 45 (a)
OneToMany
chicken
(Gallus gallus)
Aves -- 35
  • 37 (a)
OneToMany
Species where no ortholog for ZNF544 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF544 Gene

ENSEMBL:
Gene Tree for ZNF544 (if available)
TreeFam:
Gene Tree for ZNF544 (if available)

Paralogs for ZNF544 Gene

(571) SIMAP similar genes for ZNF544 Gene using alignment to 9 proteins:

genes like me logo Genes that share paralogs with ZNF544: view

Variants for ZNF544 Gene

Sequence variations from dbSNP and Humsavar for ZNF544 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
VAR_052859 -
VAR_052860 -
rs28635351 -- 58,234,268(+) CTGGG(A/G)TGAGG intron-variant
rs28693398 -- 58,230,300(+) TGTGC(C/T)CCTTT intron-variant
rs4801571 -- 58,228,282(+) CTATT(A/T)TTTTC upstream-variant-2KB, utr-variant-5-prime

Structural Variations from Database of Genomic Variants (DGV) for ZNF544 Gene

Variant ID Type Subtype PubMed ID
dgv1827n106 CNV deletion 24896259
esv1001037 CNV deletion 20482838
esv1435930 CNV deletion 17803354
esv1513336 CNV insertion 17803354
esv2087272 CNV deletion 18987734
esv2664815 CNV deletion 23128226
esv3556693 CNV deletion 23714750
esv3644928 CNV loss 21293372
esv3644929 CNV loss 21293372
esv3644930 CNV loss 21293372
esv3644931 CNV gain 21293372
esv989961 CNV insertion 20482838
nsv1058109 CNV gain 25217958
nsv1066059 CNV gain 25217958
nsv833886 CNV gain 17160897
nsv833887 CNV loss 17160897

Variation tolerance for ZNF544 Gene

Residual Variation Intolerance Score: 88% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 4.14; 61.46% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ZNF544 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ZNF544

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF544 Gene

Disorders for ZNF544 Gene

Relevant External Links for ZNF544

Genetic Association Database (GAD)
ZNF544
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ZNF544

No disorders were found for ZNF544 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF544 Gene

Publications for ZNF544 Gene

  1. Genome-wide association scan of quantitative traits for attention deficit hyperactivity disorder identifies novel associations and confirms candidate gene associations. (PMID: 18821565) Lasky-Su J. … Faraone S.V. (Am. J. Med. Genet. B Neuropsychiatr. Genet. 2008) 3 46 65
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 65
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 65
  4. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3 65
  5. Uncovering global SUMOylation signaling networks in a site-specific manner. (PMID: 25218447) Hendriks I.A. … Vertegaal A.C. (Nat. Struct. Mol. Biol. 2014) 4 65

Products for ZNF544 Gene

Sources for ZNF544 Gene

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