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Aliases for ZNF541 Gene

Aliases for ZNF541 Gene

  • Zinc Finger Protein 541 2 3

External Ids for ZNF541 Gene

Summaries for ZNF541 Gene

GeneCards Summary for ZNF541 Gene

ZNF541 (Zinc Finger Protein 541) is a Protein Coding gene. GO annotations related to this gene include chromatin binding. An important paralog of this gene is ELMSAN1.

UniProtKB/Swiss-Prot for ZNF541 Gene

  • Component of some chromatin remodeling multiprotein complex that plays a role during spermatogenesis.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF541 Gene

Genomics for ZNF541 Gene

Genomic Location for ZNF541 Gene

Start:
47,520,685 bp from pter
End:
47,572,737 bp from pter
Size:
52,053 bases
Orientation:
Minus strand

Genomic View for ZNF541 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZNF541 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF541 Gene

Regulatory Elements for ZNF541 Gene

Proteins for ZNF541 Gene

  • Protein details for ZNF541 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9H0D2-ZN541_HUMAN
    Recommended name:
    Zinc finger protein 541
    Protein Accession:
    Q9H0D2
    Secondary Accessions:
    • Q8NDK8

    Protein attributes for ZNF541 Gene

    Size:
    1346 amino acids
    Molecular mass:
    145587 Da
    Quaternary structure:
    • Interacts with DNTTIP1. Identified in a complex with KCDT19, HDAC1 and HSPA2.
    SequenceCaution:
    • Sequence=AAI01051.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=AAI01052.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=AAI01053.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=AAI01054.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=CAB66780.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=CAD38720.2; Type=Frameshift; Positions=473; Evidence={ECO:0000305};

    Alternative splice isoforms for ZNF541 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZNF541 Gene

Proteomics data for ZNF541 Gene at MOPED

Post-translational modifications for ZNF541 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF541 Gene

No data available for DME Specific Peptides for ZNF541 Gene

Domains for ZNF541 Gene

Gene Families for ZNF541 Gene

HGNC:
  • ZNF :Zinc fingers, C2H2-type

Suggested Antigen Peptide Sequences for ZNF541 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q9H0D2

UniProtKB/Swiss-Prot:

ZN541_HUMAN
Domain:
  • Contains 1 ELM2 domain.:
    • Q9H0D2
  • Contains 1 SANT domain.:
    • Q9H0D2
Similarity:
  • Contains 5 C2H2-type zinc fingers.:
    • Q9H0D2
genes like me logo Genes that share domains with ZNF541: view

Function for ZNF541 Gene

Molecular function for ZNF541 Gene

UniProtKB/Swiss-Prot Function: Component of some chromatin remodeling multiprotein complex that plays a role during spermatogenesis.

Gene Ontology (GO) - Molecular Function for ZNF541 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
GO:0003682 chromatin binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF541: view

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for ZNF541 Gene

Localization for ZNF541 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF541 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF541 Gene COMPARTMENTS Subcellular localization image for ZNF541 gene
Compartment Confidence
nucleus 3

Gene Ontology (GO) - Cellular Components for ZNF541 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000118 histone deacetylase complex ISS --
GO:0005634 nucleus ISS --
genes like me logo Genes that share ontologies with ZNF541: view

Pathways for ZNF541 Gene

SuperPathways for ZNF541 Gene

No Data Available

Interacting Proteins for ZNF541 Gene

Gene Ontology (GO) - Biological Process for ZNF541 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
GO:0007275 multicellular organismal development IEA --
GO:0007283 spermatogenesis IEA --
GO:0030154 cell differentiation IEA --
genes like me logo Genes that share ontologies with ZNF541: view

No data available for Pathways by source for ZNF541 Gene

Transcripts for ZNF541 Gene

Unigene Clusters for ZNF541 Gene

Zinc finger protein 541:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF541 Gene

ExUns: 1 ^ 2a · 2b ^ 3 ^ 4 ^ 5 ^ 6 ^ 7a · 7b ^ 8a · 8b ^ 9 ^ 10 ^ 11 ^ 12 ^ 13
SP1: - -
SP2: -
SP3:

Relevant External Links for ZNF541 Gene

GeneLoc Exon Structure for
ZNF541
ECgene alternative splicing isoforms for
ZNF541

Expression for ZNF541 Gene

mRNA expression in normal human tissues for ZNF541 Gene

mRNA differential expression in normal tissues according to GTEx for ZNF541 Gene

This gene is overexpressed in Testis (30.1).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for ZNF541 Gene

SOURCE GeneReport for Unigene cluster for ZNF541 Gene Hs.14161

genes like me logo Genes that share expressions with ZNF541: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for ZNF541 Gene

Orthologs for ZNF541 Gene

This gene was present in the common ancestor of animals.

Orthologs for ZNF541 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF541 35
  • 99.23 (n)
  • 99.11 (a)
ZNF541 36
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia ZNF541 35
  • 81.68 (n)
  • 78.5 (a)
ZNF541 36
  • 76 (a)
OneToOne
dog
(Canis familiaris)
Mammalia ZNF541 35
  • 84.17 (n)
  • 83.07 (a)
ZNF541 36
  • 80 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Zfp541 35
  • 77.94 (n)
  • 76.89 (a)
Zfp541 16
Zfp541 36
  • 74 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia ZNF541 36
  • 71 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Zfp541 35
  • 79.77 (n)
  • 78.47 (a)
chicken
(Gallus gallus)
Aves ZNF541 36
  • 33 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia ZNF541 36
  • 41 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii ZNF541 36
  • 22 (a)
OneToOne
fruit fly
(Drosophila melanogaster)
Insecta CG16779 36
  • 6 (a)
OneToMany
worm
(Caenorhabditis elegans)
Secernentea saeg-1 36
  • 11 (a)
OneToMany
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 24 (a)
OneToMany
Species with no ortholog for ZNF541:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)

Evolution for ZNF541 Gene

ENSEMBL:
Gene Tree for ZNF541 (if available)
TreeFam:
Gene Tree for ZNF541 (if available)

Paralogs for ZNF541 Gene

Paralogs for ZNF541 Gene

Selected SIMAP similar genes for ZNF541 Gene using alignment to 3 proteins:

genes like me logo Genes that share paralogs with ZNF541: view

Variants for ZNF541 Gene

Sequence variations from dbSNP and Humsavar for ZNF541 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type MAF
rs1809011 -- 47,530,178(+) ttttt(C/T)ttttt intron-variant
rs2019589 -- 47,530,357(-) AAAAT(A/C/G)CAAAA intron-variant
rs2081893 -- 47,544,021(+) TAAAA(C/T)TGCAT intron-variant
rs2340938 -- 47,535,245(-) CCAGG(C/T)GCGGT intron-variant
rs2463091 -- 47,521,168(+) GAGAG(C/G)CCGAA utr-variant-3-prime

Structural Variations from Database of Genomic Variants (DGV) for ZNF541 Gene

Variant ID Type Subtype PubMed ID
dgv1107e1 CNV Complex 17122850
nsv428366 CNV Loss 18775914
nsv912202 CNV Loss 21882294

Relevant External Links for ZNF541 Gene

HapMap Linkage Disequilibrium report
ZNF541

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF541 Gene

Disorders for ZNF541 Gene

No disorders were found for ZNF541 Gene.

No data available for UniProtKB/Swiss-Prot for ZNF541 Gene

Publications for ZNF541 Gene

  1. Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PMID: 11230166) Wiemann S. … Poustka A. (Genome Res. 2001) 2 3 4
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  3. Systematic and quantitative assessment of the ubiquitin-modified proteome. (PMID: 21906983) Kim W. … Gygi S.P. (Mol. Cell 2011) 3
  4. The DNA sequence and biology of human chromosome 19. (PMID: 15057824) Grimwood J. … Lucas S.M. (Nature 2004) 4
  5. The consensus coding sequences of human breast and colorectal cancers. (PMID: 16959974) Sjoeblom T. … Velculescu V.E. (Science 2006) 4

Products for ZNF541 Gene

  • antibodies-online peptides for ZNF541
  • antibodies-online antibodies for ZNF541
  • antibodies-online kits for ZNF541

Sources for ZNF541 Gene

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