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Aliases for ZNF534 Gene

Aliases for ZNF534 Gene

  • Zinc Finger Protein 534 2 3
  • KRAB Domain Only Protein 3 3 4
  • KRAB Domain Only 3 2 3
  • KRBO3 3 4

External Ids for ZNF534 Gene

Previous Symbols for ZNF534 Gene

  • KRBO3

Summaries for ZNF534 Gene

GeneCards Summary for ZNF534 Gene

ZNF534 (Zinc Finger Protein 534) is a Protein Coding gene. Among its related pathways are Gene Expression and Gene Expression. An important paralog of this gene is ZNF860.

UniProtKB/Swiss-Prot for ZNF534 Gene

  • May be involved in transcriptional regulation.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF534 Gene

Genomics for ZNF534 Gene

Genomic Location for ZNF534 Gene

Start:
52,429,187 bp from pter
End:
52,452,315 bp from pter
Size:
23,129 bases
Orientation:
Plus strand

Genomic View for ZNF534 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZNF534 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF534 Gene

Regulatory Elements for ZNF534 Gene

Proteins for ZNF534 Gene

  • Protein details for ZNF534 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q76KX8-ZN534_HUMAN
    Recommended name:
    Zinc finger protein 534
    Protein Accession:
    Q76KX8
    Secondary Accessions:
    • Q76KX9

    Protein attributes for ZNF534 Gene

    Size:
    674 amino acids
    Molecular mass:
    77167 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ZNF534 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZNF534 Gene

Proteomics data for ZNF534 Gene at MOPED

Post-translational modifications for ZNF534 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for ZNF534 Gene

Domains for ZNF534 Gene

Gene Families for ZNF534 Gene

HGNC:
  • ZNF :Zinc fingers, C2H2-type

Protein Domains for ZNF534 Gene

Suggested Antigen Peptide Sequences for ZNF534 Gene

Graphical View of Domain Structure for InterPro Entry

Q76KX8

UniProtKB/Swiss-Prot:

ZN534_HUMAN
Domain:
  • Contains 1 KRAB domain.:
    • Q76KX8
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.:
    • Q76KX8
Similarity:
  • Contains 17 C2H2-type zinc fingers.:
    • Q76KX8
genes like me logo Genes that share domains with ZNF534: view

Function for ZNF534 Gene

Molecular function for ZNF534 Gene

UniProtKB/Swiss-Prot Function: May be involved in transcriptional regulation.

Gene Ontology (GO) - Molecular Function for ZNF534 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding --
GO:0003677 DNA binding IEA --
GO:0003700 sequence-specific DNA binding transcription factor activity IBA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF534: view

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for ZNF534 Gene

Localization for ZNF534 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF534 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF534 Gene COMPARTMENTS Subcellular localization image for ZNF534 gene
Compartment Confidence
nucleus 4
cytosol 2

Gene Ontology (GO) - Cellular Components for ZNF534 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF534: view

Pathways for ZNF534 Gene

SuperPathways for ZNF534 Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF534: view

Pathways by source for ZNF534 Gene

2 Reactome pathways for ZNF534 Gene

Interacting Proteins for ZNF534 Gene

Gene Ontology (GO) - Biological Process for ZNF534 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IBA --
genes like me logo Genes that share ontologies with ZNF534: view

Transcripts for ZNF534 Gene

mRNA/cDNA for ZNF534 Gene

(6) REFSEQ mRNAs :
(2) Selected AceView cDNA sequences:
(5) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF534 Gene

No ASD Table

Relevant External Links for ZNF534 Gene

GeneLoc Exon Structure for
ZNF534
ECgene alternative splicing isoforms for
ZNF534

Expression for ZNF534 Gene

mRNA expression in normal human tissues for ZNF534 Gene

mRNA differential expression in normal tissues according to GTEx for ZNF534 Gene

This gene is overexpressed in Brain - Nucleus accumbens (basal ganglia) (4.6) and Brain - Cerebellar Hemisphere (4.5).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for ZNF534 Gene

SOURCE GeneReport for Unigene cluster for ZNF534 Gene Hs.447583

genes like me logo Genes that share expressions with ZNF534: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for ZNF534 Gene

Orthologs for ZNF534 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZNF534 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia -- 36
  • 85 (a)
ManyToMany
ZNF534 35
  • 98.76 (n)
  • 96.88 (a)
cow
(Bos Taurus)
Mammalia -- 36
  • 48 (a)
ManyToMany
dog
(Canis familiaris)
Mammalia -- 36
  • 49 (a)
ManyToMany
mouse
(Mus musculus)
Mammalia Gm13248 16
tropical clawed frog
(Silurana tropicalis)
Amphibia znf484 35
  • 58.8 (n)
  • 57.08 (a)
Species with no ortholog for ZNF534:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF534 Gene

ENSEMBL:
Gene Tree for ZNF534 (if available)
TreeFam:
Gene Tree for ZNF534 (if available)

Paralogs for ZNF534 Gene

Selected SIMAP similar genes for ZNF534 Gene using alignment to 4 proteins:

genes like me logo Genes that share paralogs with ZNF534: view

Variants for ZNF534 Gene

Sequence variations from dbSNP and Humsavar for ZNF534 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type MAF
rs324104 -- 52,451,254(+) GGTGC(C/T)GAGGA synonymous-codon, reference
rs324105 -- 52,451,065(+) attgc(A/G)tttgg intron-variant
rs324106 -- 52,450,976(+) ccacc(G/T)caccc intron-variant
rs324107 -- 52,450,812(+) ctcct(C/G)agtag intron-variant
rs1366257 -- 52,438,287(+) ATGTG(A/G)GAAAG missense, reference, intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF534 Gene

Variant ID Type Subtype PubMed ID
nsv833873 CNV Gain 17160897
nsv828615 CNV Loss 20364138

Relevant External Links for ZNF534 Gene

HapMap Linkage Disequilibrium report
ZNF534

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF534 Gene

Disorders for ZNF534 Gene

No disorders were found for ZNF534 Gene.

No data available for UniProtKB/Swiss-Prot for ZNF534 Gene

Publications for ZNF534 Gene

  1. Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition. (PMID: 22505724) Udeshi N.D. … Carr S.A. (Mol. Cell Proteomics 2012) 3
  2. The DNA sequence and biology of human chromosome 19. (PMID: 15057824) Grimwood J. … Lucas S.M. (Nature 2004) 4

Products for ZNF534 Gene

Sources for ZNF534 Gene

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