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Aliases for ZNF532 Gene

Aliases for ZNF532 Gene

  • Zinc Finger Protein 532 2 3
  • KIAA1629 4

External Ids for ZNF532 Gene

Summaries for ZNF532 Gene

GeneCards Summary for ZNF532 Gene

ZNF532 (Zinc Finger Protein 532) is a Protein Coding gene. An important paralog of this gene is ZNF592.

UniProtKB/Swiss-Prot for ZNF532 Gene

  • May be involved in transcriptional regulation

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF532 Gene

Genomics for ZNF532 Gene

Genomic Location for ZNF532 Gene

Start:
58,862,600 bp from pter
End:
58,986,480 bp from pter
Size:
123,881 bases
Orientation:
Plus strand

Genomic View for ZNF532 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZNF532 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF532 Gene

Regulatory Elements for ZNF532 Gene

Proteins for ZNF532 Gene

  • Protein details for ZNF532 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9HCE3-ZN532_HUMAN
    Recommended name:
    Zinc finger protein 532
    Protein Accession:
    Q9HCE3
    Secondary Accessions:
    • Q4G0V6
    • Q7L7Z7
    • Q96QR7
    • Q9NVJ6

    Protein attributes for ZNF532 Gene

    Size:
    1301 amino acids
    Molecular mass:
    141696 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAH36366.1; Type=Frameshift; Positions=1077; Evidence={ECO:0000305}; Sequence=BAA91755.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=BAB13455.1; Type=Erroneous initiation; Evidence={ECO:0000305};

neXtProt entry for ZNF532 Gene

Proteomics data for ZNF532 Gene at MOPED

Post-translational modifications for ZNF532 Gene

  • Modification sites at PhosphoSitePlus
  • Ubiquitination at Lys248

No data available for DME Specific Peptides for ZNF532 Gene

Domains for ZNF532 Gene

Gene Families for ZNF532 Gene

HGNC:
  • ZNF :Zinc fingers, C2H2-type

Protein Domains for ZNF532 Gene

UniProtKB/Swiss-Prot:

ZN532_HUMAN
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.:
    • Q9HCE3
Similarity:
  • Contains 12 C2H2-type zinc fingers.:
    • Q9HCE3
genes like me logo Genes that share domains with ZNF532: view

Function for ZNF532 Gene

Molecular function for ZNF532 Gene

UniProtKB/Swiss-Prot Function: May be involved in transcriptional regulation

Gene Ontology (GO) - Molecular Function for ZNF532 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding --
GO:0003677 DNA binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF532: view

Phenotypes for ZNF532 Gene

GenomeRNAi human phenotypes for ZNF532:
genes like me logo Genes that share phenotypes with ZNF532: view

miRNA for ZNF532 Gene

miRTarBase miRNAs that target ZNF532

No data available for Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for ZNF532 Gene

Localization for ZNF532 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF532 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF532 Gene COMPARTMENTS Subcellular localization image for ZNF532 gene
Compartment Confidence
nucleus 4
golgi apparatus 1

Gene Ontology (GO) - Cellular Components for ZNF532 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF532: view

Pathways for ZNF532 Gene

SuperPathways for ZNF532 Gene

No Data Available

Interacting Proteins for ZNF532 Gene

Gene Ontology (GO) - Biological Process for ZNF532 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF532: view

No data available for Pathways by source for ZNF532 Gene

Transcripts for ZNF532 Gene

Unigene Clusters for ZNF532 Gene

Zinc finger protein 532:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF532 Gene

ExUns: 1a · 1b ^ 2a · 2b · 2c · 2d ^ 3 ^ 4 ^ 5a · 5b · 5c ^ 6 ^ 7 ^ 8 ^ 9a · 9b · 9c · 9d · 9e · 9f · 9g ^ 10a · 10b ^ 11 ^ 12 ^ 13a ·
SP1:
SP2:
SP3: - - - - - - - - - -
SP4: - - - - - - -
SP5: - - - - - -
SP6: - - - - -
SP7: -
SP8: - -
SP9:
SP10:
SP11:
SP12:
SP13:
SP14: - - - - - - - - - - -
SP15: - - - - - - - -
SP16: - - - - - -
SP17: - - - - -
SP18: - -
SP19: - -
SP20: - - -
SP21: -
SP22: - - -
SP23:
SP24:
SP25: - - -

ExUns: 13b · 13c ^ 14 ^ 15a · 15b ^ 16 ^ 17a · 17b · 17c · 17d ^ 18a · 18b ^ 19 ^ 20a · 20b ^ 21a · 21b · 21c ^ 22a · 22b · 22c · 22d
SP1: -
SP2:
SP3:
SP4:
SP5:
SP6:
SP7:
SP8:
SP9:
SP10: - - -
SP11: - - -
SP12: - - - -
SP13: -
SP14:
SP15:
SP16:
SP17:
SP18:
SP19:
SP20: - - -
SP21:
SP22: - -
SP23:
SP24:
SP25:

Relevant External Links for ZNF532 Gene

GeneLoc Exon Structure for
ZNF532
ECgene alternative splicing isoforms for
ZNF532

Expression for ZNF532 Gene

mRNA expression in normal human tissues for ZNF532 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for ZNF532 Gene

SOURCE GeneReport for Unigene cluster for ZNF532 Gene Hs.529023

genes like me logo Genes that share expressions with ZNF532: view

Orthologs for ZNF532 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZNF532 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia LOC455444 36
  • 99.4 (n)
  • 99.2 (a)
ZNF532 37
  • 92 (a)
OneToOne
cow
(Bos Taurus)
Mammalia ZNF532 36
  • 83.29 (n)
  • 90.55 (a)
ZNF532 37
  • 90 (a)
OneToOne
dog
(Canis familiaris)
Mammalia ZNF532 36
  • 88.73 (n)
  • 94.15 (a)
ZNF532 37
  • 93 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Zfp532 16
Zfp532 37
  • 91 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia ZNF532 37
  • 90 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia ZNF532 37
  • 91 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Zfp532 36
  • 87.47 (n)
  • 92.06 (a)
chicken
(Gallus gallus)
Aves -- 37
  • 82 (a)
OneToMany
-- 37
  • 93 (a)
OneToMany
-- 37
  • 88 (a)
OneToMany
LOC100857356 36
  • 80.96 (n)
  • 88.36 (a)
lizard
(Anolis carolinensis)
Reptilia ZNF532 37
  • 86 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia Str.18390 36
znf532 36
  • 70.82 (n)
  • 75.14 (a)
zebrafish
(Danio rerio)
Actinopterygii Dr.11710 36
znf532 36
  • 65.18 (n)
  • 68.95 (a)
znf532 37
  • 66 (a)
OneToOne
sea squirt
(Ciona savignyi)
Ascidiacea -- 37
  • 27 (a)
OneToMany
Species with no ortholog for ZNF532:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ZNF532 Gene

ENSEMBL:
Gene Tree for ZNF532 (if available)
TreeFam:
Gene Tree for ZNF532 (if available)

Paralogs for ZNF532 Gene

Paralogs for ZNF532 Gene

genes like me logo Genes that share paralogs with ZNF532: view

Variants for ZNF532 Gene

Sequence variations from dbSNP and Humsavar for ZNF532 Gene

SNP ID Clin Chr 18 pos Sequence Context AA Info Type MAF
rs937815 -- 58,900,674(+) CCTTG(G/T)CTTTG intron-variant
rs952270 -- 58,895,124(+) TTGCT(A/G)AAGTT intron-variant
rs1046352 -- 58,920,607(-) ATTTC(C/G)AGCAG reference, missense, nc-transcript-variant
rs1052783 -- 58,985,371(+) ACACA(A/G)CTAAG utr-variant-3-prime
rs1052784 -- 58,985,507(+) TGCAC(A/G)ACTTC utr-variant-3-prime

Structural Variations from Database of Genomic Variants (DGV) for ZNF532 Gene

Variant ID Type Subtype PubMed ID
esv28415 CNV Loss 19812545
esv1419346 CNV Insertion 17803354
nsv2325 CNV Insertion 18451855
nsv833664 CNV Loss 17160897
nsv2326 CNV Loss 18451855

Relevant External Links for ZNF532 Gene

HapMap Linkage Disequilibrium report
ZNF532
Human Gene Mutation Database (HGMD)
ZNF532

Disorders for ZNF532 Gene

Relevant External Links for ZNF532

Genetic Association Database (GAD)
ZNF532
Human Genome Epidemiology (HuGE) Navigator
ZNF532
genes like me logo Genes that share disorders with ZNF532: view

No data available for UniProtKB/Swiss-Prot for ZNF532 Gene

Publications for ZNF532 Gene

  1. Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PMID: 10997877) Nagase T. … Ohara O. (DNA Res. 2000) 2 3 4
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3 49
  4. A data set of human endogenous protein ubiquitination sites. (PMID: 20972266) Shi Y. … Qin J. (Mol. Cell Proteomics 2011) 3
  5. A genome-wide association study identifies IL23R as an inflammatory bowel disease gene. (PMID: 17068223) Duerr R.H. … Cho J.H. (Science 2006) 49

Products for ZNF532 Gene

Sources for ZNF532 Gene

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