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Aliases for ZNF530 Gene

Aliases for ZNF530 Gene

  • Zinc Finger Protein 530 2 3 5
  • KIAA1508 4

External Ids for ZNF530 Gene

Previous GeneCards Identifiers for ZNF530 Gene

  • GC19P062803
  • GC19P058111
  • GC19P054423

Summaries for ZNF530 Gene

GeneCards Summary for ZNF530 Gene

ZNF530 (Zinc Finger Protein 530) is a Protein Coding gene. Among its related pathways are Gene Expression. GO annotations related to this gene include nucleic acid binding. An important paralog of this gene is ZNF256.

UniProtKB/Swiss-Prot for ZNF530 Gene

  • May be involved in transcriptional regulation.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF530 Gene

Genomics for ZNF530 Gene

Regulatory Elements for ZNF530 Gene

Enhancers for ZNF530 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH19F057583 0.5 ENCODE 13.6 -15.9 -15913 1.4 TBP CBX3 ZNF76 ARID4B RAD21 ZBTB40 ZEB1 ETS1 GLIS2 ZNF416 ZNF549 ZNF17 ZIK1 LOC100128398 ZNF324B MZF1 ZSCAN22 ZNF606 ZNF544 ZNF551
GH19F057681 0.5 ENCODE 13.5 +82.3 82262 1.6 PKNOX1 ATF1 CREB3L1 ARID4B SIN3A GLI4 DMAP1 ETS1 YY1 ELK1 ZNF17 ZNF549 ZNF134 ZNF773 ZNF211 ZNF544 ZNF551 ZNF749 ZNF606 ZNF543
GH19F058517 0.9 FANTOM5 ENCODE 13.3 +919.8 919824 4.9 CREB3L1 MLX ZFP64 FEZF1 DMAP1 YY1 SLC30A9 ZNF416 ZNF143 ZNF263 ZNF324B CENPBD1P1 ZNF134 LOC105372483 TRIM28 ZNF549 MZF1 ZNF324 ZBTB45 ZNF584
GH19F056954 0.2 ENCODE 13.3 -642.4 -642371 5.9 ATF1 MLX ZFP64 ARID4B YBX1 DMAP1 ZNF48 YY1 SLC30A9 ZNF416 ZNF543 ZNF134 ZNF17 ZNF805 ZNF256 ZNF264 ZNF530 LOC100506374 ZNF773 ENSG00000268392
GH19F058553 0.4 ENCODE 12.3 +957.2 957228 7.2 CREB3L1 FEZF1 DMAP1 YY1 SLC30A9 ZNF143 SP3 NFYC ZFP41 MEF2D TRIM28 LOC105372483 ZNF550 ZNF584 CENPBD1P1 ZNF776 ZNF551 ZNF418 ZIK1 ZNF606
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around ZNF530 on UCSC Golden Path with GeneCards custom track

Promoters for ZNF530 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000045627 216 1799 PKNOX1 ATF1 CREB3L1 ARID4B SIN3A GLI4 DMAP1 ZNF48 ETS1 YY1

Genomic Location for ZNF530 Gene

Chromosome:
19
Start:
57,599,885 bp from pter
End:
57,612,722 bp from pter
Size:
12,838 bases
Orientation:
Plus strand

Genomic View for ZNF530 Gene

Genes around ZNF530 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF530 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF530 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF530 Gene

Proteins for ZNF530 Gene

  • Protein details for ZNF530 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6P9A1-ZN530_HUMAN
    Recommended name:
    Zinc finger protein 530
    Protein Accession:
    Q6P9A1
    Secondary Accessions:
    • O43340
    • Q9P220

    Protein attributes for ZNF530 Gene

    Size:
    599 amino acids
    Molecular mass:
    68837 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAC24609.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305}; Sequence=BAA96032.1; Type=Miscellaneous discrepancy; Note=Intron retention.; Evidence={ECO:0000305};

neXtProt entry for ZNF530 Gene

Post-translational modifications for ZNF530 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF530 Gene

No data available for DME Specific Peptides for ZNF530 Gene

Domains & Families for ZNF530 Gene

Gene Families for ZNF530 Gene

Suggested Antigen Peptide Sequences for ZNF530 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q6P9A1

UniProtKB/Swiss-Prot:

ZN530_HUMAN :
  • Contains 1 KRAB domain.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 13 C2H2-type zinc fingers.
Domain:
  • Contains 1 KRAB domain.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 13 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF530: view

Function for ZNF530 Gene

Molecular function for ZNF530 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Gene Ontology (GO) - Molecular Function for ZNF530 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF530: view
genes like me logo Genes that share phenotypes with ZNF530: view

Animal Model Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for ZNF530 Gene

Localization for ZNF530 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF530 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF530 Gene COMPARTMENTS Subcellular localization image for ZNF530 gene
Compartment Confidence
nucleus 5
cytosol 2

Gene Ontology (GO) - Cellular Components for ZNF530 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular IEA --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF530: view

Pathways & Interactions for ZNF530 Gene

SuperPathways for ZNF530 Gene

SuperPathway Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF530: view

Pathways by source for ZNF530 Gene

2 Reactome pathways for ZNF530 Gene

Interacting Proteins for ZNF530 Gene

Gene Ontology (GO) - Biological Process for ZNF530 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF530: view

No data available for SIGNOR curated interactions for ZNF530 Gene

Transcripts for ZNF530 Gene

Unigene Clusters for ZNF530 Gene

Zinc finger protein 530:
Representative Sequences:

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF530 Gene

ExUns: 1a · 1b ^ 2 ^ 3 ^ 4a · 4b · 4c ^ 5 ^ 6a · 6b
SP1:
SP2: - - - -
SP3: -
SP4: -
SP5:

Relevant External Links for ZNF530 Gene

GeneLoc Exon Structure for
ZNF530
ECgene alternative splicing isoforms for
ZNF530

Expression for ZNF530 Gene

mRNA expression in normal human tissues for ZNF530 Gene

NURSA nuclear receptor signaling pathways regulating expression of ZNF530 Gene:

ZNF530

SOURCE GeneReport for Unigene cluster for ZNF530 Gene:

Hs.97111
genes like me logo Genes that share expression patterns with ZNF530: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for ZNF530 Gene

Orthologs for ZNF530 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF530 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF530 34 35
  • 99.33 (n)
cow
(Bos Taurus)
Mammalia ZNF154 35
  • 40 (a)
ManyToMany
dog
(Canis familiaris)
Mammalia -- 35
  • 39 (a)
ManyToMany
Species where no ortholog for ZNF530 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF530 Gene

ENSEMBL:
Gene Tree for ZNF530 (if available)
TreeFam:
Gene Tree for ZNF530 (if available)

Paralogs for ZNF530 Gene

(480) SIMAP similar genes for ZNF530 Gene using alignment to 3 proteins:

genes like me logo Genes that share paralogs with ZNF530: view

Variants for ZNF530 Gene

Sequence variations from dbSNP and Humsavar for ZNF530 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
rs10405139 -- 57,602,672(+) GTGAA(C/T)ATAAG intron-variant
rs10407985 -- 57,607,207(+) AAATC(A/T)CCTCA intron-variant, nc-transcript-variant, reference, missense
rs10408652 -- 57,607,411(+) gcaat(C/G)tcagc intron-variant, nc-transcript-variant, utr-variant-3-prime
rs10413803 -- 57,607,449(+) aagtg(A/G)ttctc intron-variant, nc-transcript-variant, utr-variant-3-prime
rs10414968 -- 57,600,530(+) GAAGG(A/G)CAGTG intron-variant

Variation tolerance for ZNF530 Gene

Residual Variation Intolerance Score: 93.8% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 3.68; 57.19% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ZNF530 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ZNF530

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for ZNF530 Gene

Disorders for ZNF530 Gene

Relevant External Links for ZNF530

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ZNF530

No disorders were found for ZNF530 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF530 Gene

Publications for ZNF530 Gene

  1. Prediction of the coding sequences of unidentified human genes. XVII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PMID: 10819331) Nagase T. … Ohara O. (DNA Res. 2000) 2 3 4 64
  2. Exome sequencing supports a de novo mutational paradigm for schizophrenia. (PMID: 21822266) Xu B. … Karayiorgou M. (Nat. Genet. 2011) 3 64
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 64
  4. The DNA sequence and biology of human chromosome 19. (PMID: 15057824) Grimwood J. … Lucas S.M. (Nature 2004) 4 64
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4 64

Products for ZNF530 Gene

Sources for ZNF530 Gene

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