ZNF529 Gene
protein-coding GIFtS: 47
GCID: GC19M037034
|
|
zinc finger protein 529
| |
Aliases
for ZNF529 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Zinc Finger Protein 5291 2 | | KIAA16151 3 |
Export aliases for ZNF529 gene to outside databasesPrevious GC identifers: GC19M041727 GC19M033502 |
Summaries
for ZNF529 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
UniProtKB/Swiss-Prot: ZN529_HUMAN, Q6P280Function: May be involved in transcriptional regulation
|
Genomic Views
for ZNF529 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000019.9 NC_018930.1 NT_011109.16
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the ZNF529 gene promoter:
Egr-3 AhR MEF-2 Nkx2-5 Arnt MEF-2A Egr-2 FAC1 aMEF-2
Other transcription factors
Search SABiosciences Chromatin IP Primers for ZNF529
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZNF529 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 19q13.13 Ensembl cytogenetic band: 19q13.12 HGNC cytogenetic band: 19q13.13ZNF529 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 19 GeneLoc Exon Structure GeneLoc location for GC19M037034: view genomic region
(about GC identifiers)
Start:
|
37,025,676 bp from pter |
End:
|
37,096,178 bp from pter |
Size:
|
70,503 bases |
Orientation:
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minus strand |
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Proteins
for ZNF529 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: ZN529_HUMAN, Q6P280 (See
protein sequence)Recommended Name: Zinc finger protein 529 Size: 530 amino acids; 62249 Da
Subcellular location: Nucleus (Probable)
Secondary accessions: Q9H731 Q9HCF7Alternative splicing: 2 isoforms: Q6P280-1 Q6P280-2 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for ZNF529: NX_Q6P280
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q6P280
ZNF529 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (3 alternative transcripts):
NP_001139121.1 NP_001139122.1 NP_066002.3
ENSEMBL proteins: ENSP00000465917 ENSP00000468594 ENSP00000334695 ENSP00000465578 ENSP00000465682 ENSP00000468619 ENSP00000466182 Reactome Protein details: Q6P280
Human Recombinant Protein Products:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005634 | nucleus |
IEA | -- |
ZNF529 for ontologies About GeneDecksing
ZNF529 Antibody Products:
Assay Products for ZNF529: |
Protein
Domains /
Families
for ZNF529 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ZNF529 for domains About GeneDecksing
4 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q6P280ProtoNet protein and cluster: Q6P280 1 Blocks protein family: IPB001909 KRAB box
UniProtKB/Swiss-Prot: ZN529_HUMAN, Q6P280Similarity: Belongs to the krueppel C2H2-type zinc-finger protein familySimilarity: Contains 12 C2H2-type zinc fingersSimilarity: Contains 1 KRAB domain |
Function
for ZNF529 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: ZN529_HUMAN, Q6P280Function: May be involved in transcriptional regulation
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF529 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF529 (see all 4)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 3): ZNF529 (NM_001145650) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ZNF529 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF529 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF529 |
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table
ZNF529 for ontologies About GeneDecksing
1 GenomeRNAi human phenotype for ZNF529:
|
Pathways & Interactions
for ZNF529 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Generic Transcription Pathway | |
Pathway sources
See GeneCards unified pathways
Show all pathways
2 
Reactome Pathways for ZNF529
ZNF529 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ZNF529
Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006351 | transcription, DNA-dependent |
IEA | -- | | GO:0006355 | regulation of transcription, DNA-dependent |
IEA | -- |
ZNF529 for ontologies About GeneDecksing
|
Drugs & Compounds
for ZNF529 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for ZNF529
Search CenterWatch for drugs/clinical trials and news about ZNF529 / ZN529
|
Transcripts
for ZNF529 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for ZNF529 gene (3 alternative transcripts): NM_001145649.1 NM_001145650.1 NM_020951.4 Unigene Cluster for ZNF529: Zinc finger protein 529 Hs.654960 [show with all ESTs]Unigene Representative Sequence: NM_0011456499 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000452073 ENST00000590656 ENST00000334116(uc002oeh.4 uc002oeg.4 uc010xth.2 uc010xti.2)
ENST00000591340 ENST00000586115 ENST00000585983 ENST00000585960 ENST00000586458
ENST00000587286
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF529 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF529 (see all 4)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 3): ZNF529 (NM_001145650) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ZNF529 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF529 |
Additional cDNA sequence: AB046835.1 AK025110.1 AK094618.1 AL109722.1 BC036578.2 BC064690.1 NR_027239.1 9 DOTS entries: DT.40212310 DT.99971817 DT.99977061 DT.100660741 DT.121470682 DT.121470697 DT.40228167 DT.91986271 DT.99939157 24/49 AceView cDNA sequences (see all 49): BM803732 F02879 BQ723028 AK025110 N48921 AI333429 AB046835 BX503547 NM_020951 BP354728 BE858324 BC036578 N71870 BP428550 BG251457 BE835504 AI333427 AA234931 BM688342 BP336437 BU726740 BX646254 BC064690 AI807166
GeneLoc Exon Structure
4 Alternative Splicing Database (ASD) splice patterns (SP) for ZNF529 About this scheme
| ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5a | · | 5b | · | 5c | ^ | 6a | · | 6b | · | 6c |
|---|
|
| SP1: | | | | | | | | | | | - | | - | | | | | | | | |
| SP2: | | | | | | | | | | | | | - | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | - | | - | | - | | | | | | | |
ECgene alternative splicing isoforms for ZNF529
|
Expression
for ZNF529 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ZNF529 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TCCTACACAG
About this image
See ZNF529 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for ZNF529
SOURCE GeneReport for Unigene cluster: Hs.654960
SABiosciences Custom PCR Arrays for ZNF529
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZNF529
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat ZNF529 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZNF529 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZNF529 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF529 |
Orthologs
for ZNF529 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
--
ENSEMBL Gene Tree for ZNF529 (if available)
TreeFam Gene Tree for ZNF529 (if available) |
Paralogs
for ZNF529 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for ZNF529 gene
- ZNF4202 ZFP302 ZNF1402 ZNF780A2 ZNF3832 ZNF7902 ZNF5822 ZFP822
- ZNF302 ZNF5732 ZNF5402 ZNF5712 ZNF3312 ZFP142 ZNF4612 ZNF2832
- ZNF4042 ZNF8292 ZNF6072 ZNF5652 ZNF5662 ENSG000002675522
18/518 SIMAP similar genes for ZNF529 using alignment to 7 protein entries: ZN529_HUMAN (see all proteins)
(see all similar genes):KRBOX4 ZNF577 MGC12518 ZNF81 ZNF596 ZNF761
ZNF78L1 ZNF705A ZFP90 ZNF195 HZF36 ZNF3
ZNF169 ZNF720 ZNF506 ZNF283 ZNF397 ZNF846
ZNF529 for paralogs About GeneDecksing
|
Genomic Variants
for ZNF529 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 19 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for ZNF529 (37025676 - 37096178 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 5 variations for ZNF529
1 CNV: 102833
4 Indels: 26270 45766 12025 40279 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ZNF529 |
|
Disorders
/ Diseases
for ZNF529 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications
for ZNF529 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ZNF529 gene integrated from 9 sources:
(articles sorted by number of sources associating them with ZNF529) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10997877)1, 2, 3 Nagase T.... Ohara O. (2000)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)
- Ubiquitin-mediated proteolysis of HuR by heat shock. (PubMed id 19322201)1 Abdelmohsen K....Gorospe M. (2009)
- hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PubMed id 17207965)1 Lamesch P.... Vidal M. (2007)
- Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)
- Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions. (PubMed id 15342556)1 Suzuki Y.... Sugano S. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
|
External Searches for ZNF529 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing ZNF529 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing ZNF529 gene
(According to HUGE)
About This Section
| |
Specialized Databases showing ZNF529 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for ZNF529 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for ZNF529 gene:
Search GeneIP for patents involving ZNF529
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for ZNF529 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for ZNF529 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ZNF529 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZNF529 | | | OriGene Protein Over-expression Lysate for ZNF529 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for ZNF529 | | OriGene 3'-UTR Clone for ZNF529 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF529 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF529 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for ZNF529 | | OriGene Custom Protein Services for ZNF529 | | | OriGene Custom Immunoassay Development | | |
| |
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 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ZNF529 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ZNF529 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZNF529 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ZNF529 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZNF529 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZNF529 |
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 |  |  |  | |
| | | | Search Tocris compounds for ZNF529 |
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 | | | ZNF529 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF529 |
|  |  |  | | | | Search ThermoFisher Antibodies for ZNF529 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF529 |
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