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Aliases for ZNF529 Gene

Aliases for ZNF529 Gene

  • Zinc Finger Protein 529 2 3 5
  • KIAA1615 4

External Ids for ZNF529 Gene

Previous GeneCards Identifiers for ZNF529 Gene

  • GC19M041727
  • GC19M037034
  • GC19M033502
  • GC19M037157
  • GC19M036677
  • GC19M036709
  • GC19M036893
  • GC19M036911
  • GC19M037448

Summaries for ZNF529 Gene

GeneCards Summary for ZNF529 Gene

ZNF529 (Zinc Finger Protein 529) is a Protein Coding gene. Among its related pathways are Gene Expression. GO annotations related to this gene include nucleic acid binding. An important paralog of this gene is ZFP14.

UniProtKB/Swiss-Prot for ZNF529 Gene

  • May be involved in transcriptional regulation.

No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF529 Gene

Genomics for ZNF529 Gene

Regulatory Elements for ZNF529 Gene

Enhancers for ZNF529 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH19G035946 1.6 FANTOM5 Ensembl ENCODE 63.2 +658.0 658019 0.8 HDGF ARNT ARID4B SIN3A FEZF1 ZNF2 ZNF302 ZNF416 ZNF143 ZNF548 ZNF567 ZNF345 TMEM147-AS1 ZNF850 ZNF529 ZNF790-AS1 HAUS5 ZNF461 ZNF790 LINC00665
GH19G035820 1.1 ENCODE 89.5 +785.2 785238 0.2 FOXA2 ARID4B FEZF1 ZNF2 ZNF302 ZNF416 ZNF143 ZNF263 SP3 MCM3 ZNF529 ZNF461 ZNF790-AS1 LINC01534 ZNF567 ZFP82 ZFP14 ZNF260 ZNF529-AS1 LINC00665
GH19G035710 2 FANTOM5 Ensembl ENCODE dbSUPER 44.1 +890.2 890219 10.0 CREB3L1 ZFP64 DMAP1 YY1 ZNF143 ZNF548 ZNF263 SP3 TBX21 ZFP41 ZFP82 ZNF529 U2AF1L4 TMEM147-AS1 LINC00665 ZNF461 ZNF567 COX6B1 ZNF792 ZNF529-AS1
GH19G037593 1.1 ENCODE 68.4 -989.3 -989289 2.0 PKNOX1 CREB3L1 ARID4B SIN3A FEZF1 DMAP1 ZNF2 YY1 SLC30A9 ZNF302 ZNF383 ZNF567 ZNF345 ZNF585B ZNF850 ZNF571 ZNF793 ZNF607 ZNF790-AS1 LINC01535
GH19G037505 1.1 ENCODE 67.5 -901.2 -901189 2.4 PKNOX1 SIN3A ZNF2 YY1 ZNF302 ZNF416 ZNF143 ZNF548 FOS SP3 ZNF793 ZNF529 ZNF383 ZNF790-AS1 ZNF345 ZNF461 ZNF607 ZNF567 ZNF850 ZNF585B
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around ZNF529 on UCSC Golden Path with GeneCards custom track

Promoters for ZNF529 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000109143 111 1801 HDGF PKNOX1 ARID4B SIN3A FEZF1 DMAP1 ZNF2 CBX5 ZNF416 ZNF143

Genomic Location for ZNF529 Gene

Chromosome:
19
Start:
36,534,518 bp from pter
End:
36,605,411 bp from pter
Size:
70,894 bases
Orientation:
Minus strand

Genomic View for ZNF529 Gene

Genes around ZNF529 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF529 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF529 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF529 Gene

Proteins for ZNF529 Gene

  • Protein details for ZNF529 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6P280-ZN529_HUMAN
    Recommended name:
    Zinc finger protein 529
    Protein Accession:
    Q6P280
    Secondary Accessions:
    • K7EKE1
    • Q9H731
    • Q9HCF7

    Protein attributes for ZNF529 Gene

    Size:
    563 amino acids
    Molecular mass:
    65865 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAH64690.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=BAB15068.1; Type=Frameshift; Positions=78; Evidence={ECO:0000305};

neXtProt entry for ZNF529 Gene

Post-translational modifications for ZNF529 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for ZNF529 Gene

Domains & Families for ZNF529 Gene

Gene Families for ZNF529 Gene

Protein Domains for ZNF529 Gene

Suggested Antigen Peptide Sequences for ZNF529 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q6P280

UniProtKB/Swiss-Prot:

ZN529_HUMAN :
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
genes like me logo Genes that share domains with ZNF529: view

Function for ZNF529 Gene

Molecular function for ZNF529 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Gene Ontology (GO) - Molecular Function for ZNF529 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF529: view
genes like me logo Genes that share phenotypes with ZNF529: view

Animal Model Products

CRISPR Products

miRNA for ZNF529 Gene

miRTarBase miRNAs that target ZNF529

Inhibitory RNA Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF529 Gene

Localization for ZNF529 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF529 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZNF529 gene
Compartment Confidence
nucleus 5
cytosol 3
golgi apparatus 2

Gene Ontology (GO) - Cellular Components for ZNF529 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular IEA --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF529: view

Pathways & Interactions for ZNF529 Gene

SuperPathways for ZNF529 Gene

SuperPathway Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF529: view

Pathways by source for ZNF529 Gene

2 Reactome pathways for ZNF529 Gene

Gene Ontology (GO) - Biological Process for ZNF529 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF529: view

No data available for SIGNOR curated interactions for ZNF529 Gene

Drugs & Compounds for ZNF529 Gene

No Compound Related Data Available

Transcripts for ZNF529 Gene

Unigene Clusters for ZNF529 Gene

Zinc finger protein 529:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF529 Gene

ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5a · 5b · 5c ^ 6a · 6b · 6c
SP1: - -
SP2: -
SP3:
SP4: - - -

Relevant External Links for ZNF529 Gene

GeneLoc Exon Structure for
ZNF529
ECgene alternative splicing isoforms for
ZNF529

Expression for ZNF529 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ZNF529 Gene

NURSA nuclear receptor signaling pathways regulating expression of ZNF529 Gene:

ZNF529

SOURCE GeneReport for Unigene cluster for ZNF529 Gene:

Hs.654960

Evidence on tissue expression from TISSUES for ZNF529 Gene

  • Nervous system(4.5)
  • Intestine(4.1)
genes like me logo Genes that share expression patterns with ZNF529: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZNF529 Gene

Orthologs for ZNF529 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF529 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF529 34 35
  • 99.29 (n)
cow
(Bos Taurus)
Mammalia ZNF529 34
  • 86.58 (n)
dog
(Canis familiaris)
Mammalia ZNF529 35
  • 80 (a)
OneToOne
Species where no ortholog for ZNF529 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF529 Gene

ENSEMBL:
Gene Tree for ZNF529 (if available)
TreeFam:
Gene Tree for ZNF529 (if available)

Paralogs for ZNF529 Gene

(531) SIMAP similar genes for ZNF529 Gene using alignment to 6 proteins:

Pseudogenes.org Pseudogenes for ZNF529 Gene

genes like me logo Genes that share paralogs with ZNF529: view

Variants for ZNF529 Gene

Sequence variations from dbSNP and Humsavar for ZNF529 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
rs1000027576 -- 36,583,680(+) AATGG(-/A)AAAAA intron-variant
rs1000059156 -- 36,595,215(+) CCTTC(A/C)GTAGC intron-variant, downstream-variant-500B
rs1000156644 -- 36,589,737(+) GTGAA(C/G)ATATA intron-variant
rs1000165260 -- 36,602,441(+) TACTC(C/T)CCTTT intron-variant
rs1000184058 -- 36,555,034(+) AACCA(C/T)GTCTG intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF529 Gene

Variant ID Type Subtype PubMed ID
dgv1778n106 CNV deletion 24896259
esv1008911 CNV deletion 20482838
esv1768990 CNV deletion 17803354
esv2205269 CNV deletion 18987734
esv2570514 CNV deletion 19546169
esv2664896 CNV deletion 23128226
esv2718504 CNV deletion 23290073
esv3556341 CNV deletion 23714750
esv3644261 CNV loss 21293372
esv3644264 CNV loss 21293372
nsv1056134 CNV loss 25217958
nsv1064851 CNV loss 25217958
nsv1071931 CNV deletion 25765185
nsv1146826 CNV deletion 26484159
nsv138053 CNV deletion 16902084
nsv833817 CNV loss 17160897

Variation tolerance for ZNF529 Gene

Residual Variation Intolerance Score: 46.3% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.13; 22.83% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ZNF529 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ZNF529

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF529 Gene

Disorders for ZNF529 Gene

Relevant External Links for ZNF529

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ZNF529

No disorders were found for ZNF529 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF529 Gene

Publications for ZNF529 Gene

  1. Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PMID: 10997877) Nagase T. … Ohara O. (DNA Res. 2000) 2 3 4 64
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 64
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 64
  4. SR protein kinases promote splicing of nonconsensus introns. (PMID: 26167880) Lipp J.J. … Guthrie C. (Nat. Struct. Mol. Biol. 2015) 3 64
  5. Ubiquitin-mediated proteolysis of HuR by heat shock. (PMID: 19322201) Abdelmohsen K. … Gorospe M. (EMBO J. 2009) 3 64

Products for ZNF529 Gene

Sources for ZNF529 Gene

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