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Aliases for ZNF526 Gene

Aliases for ZNF526 Gene

  • Zinc Finger Protein 526 2 3
  • KIAA1951 4 6

External Ids for ZNF526 Gene

Previous GeneCards Identifiers for ZNF526 Gene

  • GC19P047416
  • GC19P042724
  • GC19P039154

Summaries for ZNF526 Gene

GeneCards Summary for ZNF526 Gene

ZNF526 (Zinc Finger Protein 526) is a Protein Coding gene. An important paralog of this gene is ZNF574.

UniProtKB/Swiss-Prot for ZNF526 Gene

  • May be involved in transcriptional regulation.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF526 Gene

Genomics for ZNF526 Gene

Regulatory Elements for ZNF526 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for ZNF526 Gene

Start:
42,220,271 bp from pter
End:
42,228,201 bp from pter
Size:
7,931 bases
Orientation:
Plus strand

Genomic View for ZNF526 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZNF526 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF526 Gene

Proteins for ZNF526 Gene

  • Protein details for ZNF526 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8TF50-ZN526_HUMAN
    Recommended name:
    Zinc finger protein 526
    Protein Accession:
    Q8TF50
    Secondary Accessions:
    • B3KV29
    • Q69YI2
    • Q96E24

    Protein attributes for ZNF526 Gene

    Size:
    670 amino acids
    Molecular mass:
    73622 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAB85537.1; Type=Erroneous initiation; Evidence={ECO:0000305};

neXtProt entry for ZNF526 Gene

Proteomics data for ZNF526 Gene at MOPED

Post-translational modifications for ZNF526 Gene

  • Ubiquitination at Lys570
  • Modification sites at PhosphoSitePlus

Other Protein References for ZNF526 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ZNF526 Gene

Domains for ZNF526 Gene

Gene Families for ZNF526 Gene

HGNC:
  • ZNF :Zinc fingers, C2H2-type

Protein Domains for ZNF526 Gene

Suggested Antigen Peptide Sequences for ZNF526 Gene

Graphical View of Domain Structure for InterPro Entry

Q8TF50

UniProtKB/Swiss-Prot:

ZN526_HUMAN :
  • Q8TF50
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 13 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF526: view

Function for ZNF526 Gene

Molecular function for ZNF526 Gene

UniProtKB/Swiss-Prot Function: May be involved in transcriptional regulation.

Gene Ontology (GO) - Molecular Function for ZNF526 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF526: view

Animal Model Products

CRISPR Products

miRNA for ZNF526 Gene

miRTarBase miRNAs that target ZNF526

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for ZNF526 Gene

Localization for ZNF526 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF526 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF526 Gene COMPARTMENTS Subcellular localization image for ZNF526 gene
Compartment Confidence
nucleus 4

Gene Ontology (GO) - Cellular Components for ZNF526 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF526: view

Pathways for ZNF526 Gene

SuperPathways for ZNF526 Gene

No Data Available

Interacting Proteins for ZNF526 Gene

Gene Ontology (GO) - Biological Process for ZNF526 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF526: view

No data available for Pathways by source for ZNF526 Gene

Transcripts for ZNF526 Gene

mRNA/cDNA for ZNF526 Gene

Unigene Clusters for ZNF526 Gene

Zinc finger protein 526:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZNF526

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF526 Gene

ExUns: 1a · 1b · 1c ^ 2 ^ 3a · 3b
SP1: -
SP2:

Relevant External Links for ZNF526 Gene

GeneLoc Exon Structure for
ZNF526
ECgene alternative splicing isoforms for
ZNF526

Expression for ZNF526 Gene

mRNA expression in normal human tissues for ZNF526 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for ZNF526 Gene

SOURCE GeneReport for Unigene cluster for ZNF526 Gene Hs.137282

genes like me logo Genes that share expressions with ZNF526: view

In Situ Assay Products

No data available for mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ZNF526 Gene

Orthologs for ZNF526 Gene

This gene was present in the common ancestor of animals.

Orthologs for ZNF526 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF526 35
  • 99.6 (n)
  • 99.1 (a)
ZNF526 36
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia ZNF526 35
  • 84.74 (n)
  • 86.98 (a)
ZNF526 36
  • 86 (a)
OneToOne
dog
(Canis familiaris)
Mammalia ZNF526 35
  • 85.22 (n)
  • 88.36 (a)
ZNF526 36
  • 87 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Zfp526 35
  • 82.76 (n)
  • 86.21 (a)
Zfp526 16
Zfp526 36
  • 86 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia ZNF526 36
  • 65 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Zfp526 35
  • 82.65 (n)
  • 86.54 (a)
lizard
(Anolis carolinensis)
Reptilia -- 36
  • 20 (a)
ManyToMany
tropical clawed frog
(Silurana tropicalis)
Amphibia Str.8424 35
zebrafish
(Danio rerio)
Actinopterygii znf526 36
  • 24 (a)
OneToOne
worm
(Caenorhabditis elegans)
Secernentea Y48G8AL.10 36
  • 10 (a)
OneToMany
Species with no ortholog for ZNF526:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for ZNF526 Gene

ENSEMBL:
Gene Tree for ZNF526 (if available)
TreeFam:
Gene Tree for ZNF526 (if available)

Paralogs for ZNF526 Gene

Paralogs for ZNF526 Gene

Selected SIMAP similar genes for ZNF526 Gene using alignment to 3 proteins:

genes like me logo Genes that share paralogs with ZNF526: view

Variants for ZNF526 Gene

Sequence variations from dbSNP and Humsavar for ZNF526 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type MAF
rs1205965 -- 42,223,413(+) caggc(A/G)ggcag intron-variant
rs3810150 -- 42,225,296(-) ATGCC(A/G)GGCTG reference, missense
rs3810151 Likely benign, - 42,224,684(-) GGCCA(A/G)CATTC missense, reference
rs4803529 -- 42,224,090(+) GGAGC(A/G)AGAGG intron-variant
rs7251519 -- 42,227,684(+) aaccc(A/G)ggagg utr-variant-3-prime

Structural Variations from Database of Genomic Variants (DGV) for ZNF526 Gene

Variant ID Type Subtype PubMed ID
nsv522854 CNV Gain 19592680
nsv520239 CNV Loss 19592680
nsv911782 CNV Loss 21882294
nsv833833 CNV Loss 17160897
nsv526186 CNV Gain 19592680

Relevant External Links for ZNF526 Gene

HapMap Linkage Disequilibrium report
ZNF526
Human Gene Mutation Database (HGMD)
ZNF526

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF526 Gene

Disorders for ZNF526 Gene

No disorders were found for ZNF526 Gene.

No data available for UniProtKB/Swiss-Prot for ZNF526 Gene

Publications for ZNF526 Gene

  1. Prediction of the coding sequences of unidentified human genes. XXII. The complete sequences of 50 new cDNA clones which code for large proteins. (PMID: 11853319) Nagase T. … Ohara O. (DNA Res. 2001) 2 3 4
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4
  4. The full-ORF clone resource of the German cDNA consortium. (PMID: 17974005) Bechtel S. … Schupp I. (BMC Genomics 2007) 4
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for ZNF526 Gene

Sources for ZNF526 Gene

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