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Aliases for ZNF526 Gene

Aliases for ZNF526 Gene

  • Zinc Finger Protein 526 2 3 5
  • KIAA1951 4

External Ids for ZNF526 Gene

Previous GeneCards Identifiers for ZNF526 Gene

  • GC19P047416
  • GC19P042724
  • GC19P039154

Summaries for ZNF526 Gene

GeneCards Summary for ZNF526 Gene

ZNF526 (Zinc Finger Protein 526) is a Protein Coding gene. An important paralog of this gene is ZNF574.

UniProtKB/Swiss-Prot for ZNF526 Gene

  • May be involved in transcriptional regulation.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF526 Gene

Genomics for ZNF526 Gene

Regulatory Elements for ZNF526 Gene

Enhancers for ZNF526 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around ZNF526 on UCSC Golden Path with GeneCards custom track

Promoters for ZNF526 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around ZNF526 on UCSC Golden Path with GeneCards custom track

Genomic Location for ZNF526 Gene

Chromosome:
19
Start:
42,220,271 bp from pter
End:
42,228,201 bp from pter
Size:
7,931 bases
Orientation:
Plus strand

Genomic View for ZNF526 Gene

Genes around ZNF526 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF526 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF526 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF526 Gene

Proteins for ZNF526 Gene

  • Protein details for ZNF526 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8TF50-ZN526_HUMAN
    Recommended name:
    Zinc finger protein 526
    Protein Accession:
    Q8TF50
    Secondary Accessions:
    • B3KV29
    • Q69YI2
    • Q96E24

    Protein attributes for ZNF526 Gene

    Size:
    670 amino acids
    Molecular mass:
    73622 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAB85537.1; Type=Erroneous initiation; Evidence={ECO:0000305};

neXtProt entry for ZNF526 Gene

Proteomics data for ZNF526 Gene at MOPED

Post-translational modifications for ZNF526 Gene

  • Ubiquitination at Lys 570
  • Modification sites at PhosphoSitePlus

Other Protein References for ZNF526 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ZNF526 Gene

Domains & Families for ZNF526 Gene

Gene Families for ZNF526 Gene

Protein Domains for ZNF526 Gene

Suggested Antigen Peptide Sequences for ZNF526 Gene

Graphical View of Domain Structure for InterPro Entry

Q8TF50

UniProtKB/Swiss-Prot:

ZN526_HUMAN :
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 13 C2H2-type zinc fingers.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 13 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF526: view

Function for ZNF526 Gene

Molecular function for ZNF526 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.
genes like me logo Genes that share phenotypes with ZNF526: view

Animal Model Products

CRISPR Products

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF526 Gene

Localization for ZNF526 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF526 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF526 Gene COMPARTMENTS Subcellular localization image for ZNF526 gene
Compartment Confidence
nucleus 5
cytosol 2
golgi apparatus 2

No data available for Gene Ontology (GO) - Cellular Components for ZNF526 Gene

Pathways & Interactions for ZNF526 Gene

SuperPathways for ZNF526 Gene

No Data Available

Interacting Proteins for ZNF526 Gene

Gene Ontology (GO) - Biological Process for ZNF526 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF526: view

No data available for Pathways by source and SIGNOR curated interactions for ZNF526 Gene

Drugs & Compounds for ZNF526 Gene

No Compound Related Data Available

Transcripts for ZNF526 Gene

mRNA/cDNA for ZNF526 Gene

Unigene Clusters for ZNF526 Gene

Zinc finger protein 526:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF526 Gene

ExUns: 1a · 1b · 1c ^ 2 ^ 3a · 3b
SP1: -
SP2:

Relevant External Links for ZNF526 Gene

GeneLoc Exon Structure for
ZNF526
ECgene alternative splicing isoforms for
ZNF526

Expression for ZNF526 Gene

mRNA expression in normal human tissues for ZNF526 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for ZNF526 Gene

This gene is overexpressed in Urinary Bladder (36.8) and Fetal ovary (30.5).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MOPED, and MaxQB for ZNF526 Gene



SOURCE GeneReport for Unigene cluster for ZNF526 Gene Hs.137282

genes like me logo Genes that share expression patterns with ZNF526: view

Primer Products

No data available for mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for ZNF526 Gene

Orthologs for ZNF526 Gene

This gene was present in the common ancestor of animals.

Orthologs for ZNF526 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia ZNF526 35
  • 84.74 (n)
  • 86.98 (a)
ZNF526 36
  • 86 (a)
OneToOne
dog
(Canis familiaris)
Mammalia ZNF526 35
  • 85.22 (n)
  • 88.36 (a)
ZNF526 36
  • 87 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Zfp526 35
  • 82.76 (n)
  • 86.21 (a)
Zfp526 16
Zfp526 36
  • 86 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia ZNF526 35
  • 99.6 (n)
  • 99.1 (a)
ZNF526 36
  • 99 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Zfp526 35
  • 82.65 (n)
  • 86.54 (a)
oppossum
(Monodelphis domestica)
Mammalia ZNF526 36
  • 65 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia -- 36
  • 20 (a)
ManyToMany
tropical clawed frog
(Silurana tropicalis)
Amphibia Str.8424 35
zebrafish
(Danio rerio)
Actinopterygii znf526 36
  • 24 (a)
OneToOne
worm
(Caenorhabditis elegans)
Secernentea Y48G8AL.10 36
  • 10 (a)
OneToMany
Species with no ortholog for ZNF526:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for ZNF526 Gene

ENSEMBL:
Gene Tree for ZNF526 (if available)
TreeFam:
Gene Tree for ZNF526 (if available)

Paralogs for ZNF526 Gene

Paralogs for ZNF526 Gene

(7) SIMAP similar genes for ZNF526 Gene using alignment to 3 proteins:

genes like me logo Genes that share paralogs with ZNF526: view

Variants for ZNF526 Gene

Sequence variations from dbSNP and Humsavar for ZNF526 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
rs3810151 - 42,224,684(-) GGCCA(A/G)CATTC reference, missense
rs17850994 - 42,225,935(+) TGCTT(C/T)TTTGG reference, missense
rs1205965 -- 42,223,413(+) caggc(A/G)ggcag intron-variant
rs140577838 -- 42,228,262(+) AGCTA(A/G)GCAGA downstream-variant-500B
rs140760551 -- 42,223,512(+) TGCAG(G/T)CGCCT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF526 Gene

Variant ID Type Subtype PubMed ID
nsv522854 CNV Gain 19592680
nsv520239 CNV Loss 19592680
nsv911782 CNV Loss 21882294
nsv833833 CNV Loss 17160897
nsv526186 CNV Gain 19592680

Variation tolerance for ZNF526 Gene

Residual Variation Intolerance Score: 20% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 4.58; 65.14% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ZNF526 Gene

Human Gene Mutation Database (HGMD)
ZNF526

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF526 Gene

Disorders for ZNF526 Gene

Relevant External Links for ZNF526

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ZNF526

No disorders were found for ZNF526 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF526 Gene

Publications for ZNF526 Gene

  1. Prediction of the coding sequences of unidentified human genes. XXII. The complete sequences of 50 new cDNA clones which code for large proteins. (PMID: 11853319) Nagase T. … Ohara O. (DNA Res. 2001) 2 3 4 67
  2. A human interactome in three quantitative dimensions organized by stoichiometries and abundances. (PMID: 26496610) Hein M.Y. … Mann M. (Cell 2015) 3
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for ZNF526 Gene

Sources for ZNF526 Gene

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