Free for academic non-profit institutions. Other users need a Commercial license

Aliases for ZNF525 Gene

Aliases for ZNF525 Gene

  • Zinc Finger Protein 525 2 3
  • KIAA1979 4

External Ids for ZNF525 Gene

Summaries for ZNF525 Gene

GeneCards Summary for ZNF525 Gene

ZNF525 (Zinc Finger Protein 525) is a Protein Coding gene. An important paralog of this gene is ZNF860.

UniProtKB/Swiss-Prot for ZNF525 Gene

  • May be involved in transcriptional regulation

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF525 Gene

Genomics for ZNF525 Gene

Genomic Location for ZNF525 Gene

Start:
53,330,675 bp from pter
End:
53,392,217 bp from pter
Size:
61,543 bases
Orientation:
Plus strand

Genomic View for ZNF525 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZNF525 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF525 Gene

Regulatory Elements for ZNF525 Gene

Proteins for ZNF525 Gene

  • Protein details for ZNF525 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8N782-ZN525_HUMAN
    Recommended name:
    Zinc finger protein 525
    Protein Accession:
    Q8N782
    Secondary Accessions:
    • Q8TF23

    Protein attributes for ZNF525 Gene

    Size:
    197 amino acids
    Molecular mass:
    23070 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAB85565.1; Type=Erroneous translation; Note=Wrong choice of CDS.; Evidence={ECO:0000305}; Sequence=BAC05417.1; Type=Frameshift; Positions=103; Evidence={ECO:0000305};

neXtProt entry for ZNF525 Gene

Proteomics data for ZNF525 Gene at MOPED

Post-translational modifications for ZNF525 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF525 Gene

No data available for DME Specific Peptides for ZNF525 Gene

Domains for ZNF525 Gene

Gene Families for ZNF525 Gene

HGNC:
  • ZNF :Zinc fingers, C2H2-type

Protein Domains for ZNF525 Gene

UniProtKB/Swiss-Prot:

ZN525_HUMAN
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.:
    • Q8N782
Similarity:
  • Contains 7 C2H2-type zinc fingers.:
    • Q8N782
genes like me logo Genes that share domains with ZNF525: view

Function for ZNF525 Gene

Molecular function for ZNF525 Gene

UniProtKB/Swiss-Prot Function: May be involved in transcriptional regulation

Gene Ontology (GO) - Molecular Function for ZNF525 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding --
GO:0003677 DNA binding IEA --
GO:0003700 sequence-specific DNA binding transcription factor activity IBA --
GO:0003735 structural constituent of ribosome --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF525: view

miRNA for ZNF525 Gene

miRTarBase miRNAs that target ZNF525

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for ZNF525 Gene

Localization for ZNF525 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF525 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF525 Gene COMPARTMENTS Subcellular localization image for ZNF525 gene
Compartment Confidence
nucleus 3
cytosol 2

Gene Ontology (GO) - Cellular Components for ZNF525 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular --
GO:0005634 nucleus IEA --
GO:0005840 ribosome --
genes like me logo Genes that share ontologies with ZNF525: view

Pathways for ZNF525 Gene

SuperPathways for ZNF525 Gene

No Data Available

Interacting Proteins for ZNF525 Gene

Gene Ontology (GO) - Biological Process for ZNF525 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IBA --
GO:0006412 translation --
genes like me logo Genes that share ontologies with ZNF525: view

No data available for Pathways by source for ZNF525 Gene

Transcripts for ZNF525 Gene

mRNA/cDNA for ZNF525 Gene

(2) Additional mRNA sequences :
(11) Selected AceView cDNA sequences:
(9) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ZNF525 Gene

Zinc finger protein 525:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF525 Gene

No ASD Table

Relevant External Links for ZNF525 Gene

GeneLoc Exon Structure for
ZNF525
ECgene alternative splicing isoforms for
ZNF525

Expression for ZNF525 Gene

mRNA expression in normal human tissues for ZNF525 Gene

SOURCE GeneReport for Unigene cluster for ZNF525 Gene Hs.352638

genes like me logo Genes that share expressions with ZNF525: view

Orthologs for ZNF525 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF525 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF525 37
  • 96 (a)
OneToOne
cow
(Bos Taurus)
Mammalia -- 37
  • 34 (a)
ManyToMany
dog
(Canis familiaris)
Mammalia -- 37
  • 45 (a)
ManyToMany
Species with no ortholog for ZNF525:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF525 Gene

ENSEMBL:
Gene Tree for ZNF525 (if available)
TreeFam:
Gene Tree for ZNF525 (if available)

Paralogs for ZNF525 Gene

Selected SIMAP similar genes for ZNF525 Gene using alignment to 6 proteins:

genes like me logo Genes that share paralogs with ZNF525: view

Variants for ZNF525 Gene

Sequence variations from dbSNP and Humsavar for ZNF525 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type MAF
rs1529483 -- 53,366,152(-) AGAAC(A/T)CGGCC intron-variant
rs1529484 -- 53,366,133(-) ACCGG(A/G)GCTGC intron-variant
rs1817396 -- 53,383,782(-) TGAAC(G/T)GCAAT nc-transcript-variant
rs1824791 -- 53,383,768(-) TGAAC(A/G)ATGTC nc-transcript-variant
rs2115303 -- 53,365,182(-) TCCCA(G/T)CTACT upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for ZNF525 Gene

Variant ID Type Subtype PubMed ID
esv2718787 CNV Deletion 23290073
nsv912342 CNV Gain 21882294
esv2718812 CNV Deletion 23290073
nsv912352 CNV Gain 21882294
esv2670793 CNV Deletion 23128226
dgv571e201 CNV Deletion 23290073
nsv512593 CNV Loss 21212237
nsv458767 CNV Loss 19166990
esv2718819 CNV Deletion 23290073
esv2659102 CNV Deletion 23128226
esv8848 CNV Loss 19470904
nsv521988 CNV Loss 19592680
nsv527524 CNV Loss 19592680
nsv912353 CNV Loss 21882294
nsv912354 CNV Loss 21882294
esv2718821 CNV Deletion 23290073
esv2368045 CNV Deletion 18987734
esv2462032 CNV Deletion 19546169

Relevant External Links for ZNF525 Gene

HapMap Linkage Disequilibrium report
ZNF525

Disorders for ZNF525 Gene

Relevant External Links for ZNF525

Genetic Association Database (GAD)
ZNF525
genes like me logo Genes that share disorders with ZNF525: view

No data available for UniProtKB/Swiss-Prot for ZNF525 Gene

Publications for ZNF525 Gene

  1. Prediction of the coding sequences of unidentified human genes. XXII. The complete sequences of 50 new cDNA clones which code for large proteins. (PMID: 11853319) Nagase T. … Ohara O. (DNA Res. 2001) 2 3 4
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  4. Dynamics of cullin-RING ubiquitin ligase network revealed by systematic quantitative proteomics. (PMID: 21145461) Bennett E.J. … Harper J.W. (Cell 2010) 3
  5. Systematic and quantitative assessment of the ubiquitin-modified proteome. (PMID: 21906983) Kim W. … Gygi S.P. (Mol. Cell 2011) 3

Products for ZNF525 Gene

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat
  • QIAGEN qRT-PCR Assays for microRNAs that regulate ZNF525
    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat
    • Predesigned siRNA for gene silencing in human,mouse,rat for ZNF525
    • Block miRNA regulation of ZNF525 using miScript Target Protectors

    Sources for ZNF525 Gene

    Back to Top

    Content