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Aliases for ZNF514 Gene

Aliases for ZNF514 Gene

  • Zinc Finger Protein 514 2 3 5

External Ids for ZNF514 Gene

Previous GeneCards Identifiers for ZNF514 Gene

  • GC02M095298
  • GC02M095235
  • GC02M095813
  • GC02M089842

Summaries for ZNF514 Gene

GeneCards Summary for ZNF514 Gene

ZNF514 (Zinc Finger Protein 514) is a Protein Coding gene. Among its related pathways are Gene Expression. GO annotations related to this gene include nucleic acid binding and transcription factor activity, sequence-specific DNA binding. An important paralog of this gene is ZFP69.

UniProtKB/Swiss-Prot for ZNF514 Gene

  • May be involved in transcriptional regulation.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF514 Gene

Genomics for ZNF514 Gene

Regulatory Elements for ZNF514 Gene

Promoters for ZNF514 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around ZNF514 on UCSC Golden Path with GeneCards custom track

Genomic Location for ZNF514 Gene

Chromosome:
2
Start:
95,130,110 bp from pter
End:
95,165,413 bp from pter
Size:
35,304 bases
Orientation:
Minus strand

Genomic View for ZNF514 Gene

Genes around ZNF514 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF514 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF514 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF514 Gene

Proteins for ZNF514 Gene

  • Protein details for ZNF514 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q96K75-ZN514_HUMAN
    Recommended name:
    Zinc finger protein 514
    Protein Accession:
    Q96K75
    Secondary Accessions:
    • Q5JPJ3

    Protein attributes for ZNF514 Gene

    Size:
    400 amino acids
    Molecular mass:
    45938 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZNF514 Gene

Proteomics data for ZNF514 Gene at MOPED

Post-translational modifications for ZNF514 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF514 Gene

Antibody Products

No data available for DME Specific Peptides for ZNF514 Gene

Domains & Families for ZNF514 Gene

Gene Families for ZNF514 Gene

Protein Domains for ZNF514 Gene

Suggested Antigen Peptide Sequences for ZNF514 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q96K75

UniProtKB/Swiss-Prot:

ZN514_HUMAN :
  • Contains 1 KRAB domain.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 7 C2H2-type zinc fingers.
Domain:
  • Contains 1 KRAB domain.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 7 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF514: view

Function for ZNF514 Gene

Molecular function for ZNF514 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.
genes like me logo Genes that share phenotypes with ZNF514: view

Animal Model Products

CRISPR Products

miRNA for ZNF514 Gene

miRTarBase miRNAs that target ZNF514

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF514 Gene

Localization for ZNF514 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF514 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF514 Gene COMPARTMENTS Subcellular localization image for ZNF514 gene
Compartment Confidence
nucleus 5
cytosol 2

No data available for Gene Ontology (GO) - Cellular Components for ZNF514 Gene

Pathways & Interactions for ZNF514 Gene

SuperPathways for ZNF514 Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF514: view

Pathways by source for ZNF514 Gene

2 Reactome pathways for ZNF514 Gene

Interacting Proteins for ZNF514 Gene

Gene Ontology (GO) - Biological Process for ZNF514 Gene

None

No data available for SIGNOR curated interactions for ZNF514 Gene

Drugs & Compounds for ZNF514 Gene

No Compound Related Data Available

Transcripts for ZNF514 Gene

Unigene Clusters for ZNF514 Gene

Zinc finger protein 514:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF514 Gene

ExUns: 1a · 1b · 1c · 1d · 1e ^ 2a · 2b ^ 3a · 3b · 3c ^ 4a · 4b · 4c ^ 5 ^ 6a · 6b · 6c
SP1: - - - - - -
SP2: -
SP3: - -
SP4: - - - - -
SP5:
SP6:

Relevant External Links for ZNF514 Gene

GeneLoc Exon Structure for
ZNF514
ECgene alternative splicing isoforms for
ZNF514

Expression for ZNF514 Gene

mRNA expression in normal human tissues for ZNF514 Gene

SOURCE GeneReport for Unigene cluster for ZNF514 Gene Hs.655109

genes like me logo Genes that share expression patterns with ZNF514: view

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for ZNF514 Gene

Orthologs for ZNF514 Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for ZNF514 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia ZNF514 35
  • 86.08 (n)
  • 79.5 (a)
ZNF514 36
  • 62 (a)
OneToOne
dog
(Canis familiaris)
Mammalia ZNF514 35
  • 87 (n)
  • 82.78 (a)
ZNF514 36
  • 56 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia ZNF514 35
  • 99.33 (n)
  • 99 (a)
ZNF514 36
  • 99 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 37 (a)
OneToMany
-- 36
  • 42 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 43 (a)
OneToMany
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes ZAP1 38
Species with no ortholog for ZNF514:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF514 Gene

ENSEMBL:
Gene Tree for ZNF514 (if available)
TreeFam:
Gene Tree for ZNF514 (if available)

Paralogs for ZNF514 Gene

Paralogs for ZNF514 Gene

(509) SIMAP similar genes for ZNF514 Gene using alignment to 2 proteins:

Pseudogenes.org Pseudogenes for ZNF514 Gene

genes like me logo Genes that share paralogs with ZNF514: view

Variants for ZNF514 Gene

Sequence variations from dbSNP and Humsavar for ZNF514 Gene

SNP ID Clin Chr 02 pos Sequence Context AA Info Type
rs1128971 -- 95,145,347(-) ttgtc(A/G)gtctt intron-variant, utr-variant-3-prime
rs1128973 -- 95,145,321(-) atgtt(A/G)atgct intron-variant, utr-variant-3-prime
rs1128976 -- 95,145,292(-) tccaa(A/G)gagag intron-variant, utr-variant-3-prime
rs2001254 -- 95,143,493(+) GCATG(C/T)CTGTA intron-variant
rs2320621 -- 95,131,928(-) tgacc(G/T)taagc intron-variant

Variation tolerance for ZNF514 Gene

Residual Variation Intolerance Score: 28.3% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.46; 28.48% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ZNF514 Gene

HapMap Linkage Disequilibrium report
ZNF514

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for ZNF514 Gene

Disorders for ZNF514 Gene

Relevant External Links for ZNF514

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ZNF514

No disorders were found for ZNF514 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF514 Gene

Publications for ZNF514 Gene

  1. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PMID: 15815621) Hillier L.W. … Wilson R.K. (Nature 2005) 3 4 67
  2. The protein interaction landscape of the human CMGC kinase group. (PMID: 23602568) Varjosalo M. … Gstaiger M. (Cell Rep 2013) 3
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for ZNF514 Gene

Sources for ZNF514 Gene

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