Free for academic non-profit institutions. Other users need a Commercial license

Aliases for ZNF512 Gene

Aliases for ZNF512 Gene

  • Zinc Finger Protein 512 2 3 5
  • KIAA1805 4

External Ids for ZNF512 Gene

Previous GeneCards Identifiers for ZNF512 Gene

  • GC02P027780
  • GC02P027717
  • GC02P027659
  • GC02P027805
  • GC02P027547

Summaries for ZNF512 Gene

Entrez Gene Summary for ZNF512 Gene

  • This gene encodes a protein containing four putative zinc finger motifs. Zinc finger motifs may bind to proteins or nucleic acids. Zinc finger-containing proteins are involved in a variety of processes, including regulation of transcription. Alternative splicing results in multiple transcript variants for this gene. [provided by RefSeq, Sep 2012]

GeneCards Summary for ZNF512 Gene

ZNF512 (Zinc Finger Protein 512) is a Protein Coding gene. An important paralog of this gene is ZNF512B.

UniProtKB/Swiss-Prot for ZNF512 Gene

  • May be involved in transcriptional regulation.

No data available for Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF512 Gene

Genomics for ZNF512 Gene

Regulatory Elements for ZNF512 Gene

Enhancers for ZNF512 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around ZNF512 on UCSC Golden Path with GeneCards custom track

Promoters for ZNF512 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around ZNF512 on UCSC Golden Path with GeneCards custom track

Genomic Location for ZNF512 Gene

Chromosome:
2
Start:
27,582,969 bp from pter
End:
27,623,215 bp from pter
Size:
40,247 bases
Orientation:
Plus strand

Genomic View for ZNF512 Gene

Genes around ZNF512 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF512 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF512 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF512 Gene

Proteins for ZNF512 Gene

  • Protein details for ZNF512 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q96ME7-ZN512_HUMAN
    Recommended name:
    Zinc finger protein 512
    Protein Accession:
    Q96ME7
    Secondary Accessions:
    • B4DSM5
    • Q53RZ7
    • Q86XK6
    • Q96JM0

    Protein attributes for ZNF512 Gene

    Size:
    567 amino acids
    Molecular mass:
    64682 Da
    Quaternary structure:
    No Data Available

    Three dimensional structures from OCA and Proteopedia for ZNF512 Gene

    Alternative splice isoforms for ZNF512 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZNF512 Gene

Proteomics data for ZNF512 Gene at MOPED

Post-translational modifications for ZNF512 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for ZNF512 Gene

Domains & Families for ZNF512 Gene

Gene Families for ZNF512 Gene

Protein Domains for ZNF512 Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

Q96ME7

UniProtKB/Swiss-Prot:

ZN512_HUMAN :
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 4 C2H2-type zinc fingers.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 4 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF512: view

Function for ZNF512 Gene

Molecular function for ZNF512 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.
genes like me logo Genes that share phenotypes with ZNF512: view

Animal Model Products

CRISPR Products

miRNA for ZNF512 Gene

miRTarBase miRNAs that target ZNF512

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF512 Gene

Localization for ZNF512 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF512 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF512 Gene COMPARTMENTS Subcellular localization image for ZNF512 gene
Compartment Confidence
nucleus 5

No data available for Gene Ontology (GO) - Cellular Components for ZNF512 Gene

Pathways & Interactions for ZNF512 Gene

SuperPathways for ZNF512 Gene

No Data Available

Interacting Proteins for ZNF512 Gene

Gene Ontology (GO) - Biological Process for ZNF512 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF512: view

No data available for Pathways by source and SIGNOR curated interactions for ZNF512 Gene

Drugs & Compounds for ZNF512 Gene

No Compound Related Data Available

Transcripts for ZNF512 Gene

Unigene Clusters for ZNF512 Gene

Zinc finger protein 512:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF512 Gene

No ASD Table

Relevant External Links for ZNF512 Gene

GeneLoc Exon Structure for
ZNF512
ECgene alternative splicing isoforms for
ZNF512

Expression for ZNF512 Gene

mRNA expression in normal human tissues for ZNF512 Gene

Protein differential expression in normal tissues from HIPED for ZNF512 Gene

This gene is overexpressed in Peripheral blood mononuclear cells (14.0), Adrenal (11.4), CD8 Tcells (9.6), and Retina (7.5).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MOPED, and MaxQB for ZNF512 Gene



SOURCE GeneReport for Unigene cluster for ZNF512 Gene Hs.529178

genes like me logo Genes that share expression patterns with ZNF512: view

Protein tissue co-expression partners for ZNF512 Gene

- Elite partner

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ZNF512 Gene

Orthologs for ZNF512 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZNF512 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia ZNF512 35
  • 92.59 (n)
  • 95.77 (a)
ZNF512 36
  • 96 (a)
OneToOne
dog
(Canis familiaris)
Mammalia ZNF512 35
  • 92.82 (n)
  • 95.41 (a)
-- 36
  • 95 (a)
OneToMany
-- 36
  • 96 (a)
OneToMany
-- 36
  • 93 (a)
OneToMany
mouse
(Mus musculus)
Mammalia Zfp512 35
  • 86.05 (n)
  • 87.84 (a)
Zfp512 16
Zfp512 36
  • 86 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia ZNF512 35
  • 99.65 (n)
  • 100 (a)
ZNF512 36
  • 100 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Zfp512 35
  • 84.44 (n)
  • 86.94 (a)
oppossum
(Monodelphis domestica)
Mammalia ZNF512 36
  • 70 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia ZNF512 36
  • 66 (a)
OneToOne
chicken
(Gallus gallus)
Aves ZNF512 35
  • 62.41 (n)
  • 59.43 (a)
ZNF512 36
  • 53 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia ZNF512 36
  • 59 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii znf512 36
  • 37 (a)
OneToOne
Species with no ortholog for ZNF512:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ZNF512 Gene

ENSEMBL:
Gene Tree for ZNF512 (if available)
TreeFam:
Gene Tree for ZNF512 (if available)

Paralogs for ZNF512 Gene

Paralogs for ZNF512 Gene

(2) SIMAP similar genes for ZNF512 Gene using alignment to 3 proteins:

genes like me logo Genes that share paralogs with ZNF512: view

Variants for ZNF512 Gene

Sequence variations from dbSNP and Humsavar for ZNF512 Gene

SNP ID Clin Chr 02 pos Sequence Context AA Info Type
rs1881395 -- 27,615,682(+) CTTCA(A/G)AATTT intron-variant
rs1881396 -- 27,621,734(+) GCTCC(G/T)CTTGC utr-variant-3-prime
rs1881397 -- 27,609,418(+) AGGAT(A/G)TCATA intron-variant
rs1919129 -- 27,595,854(-) atact(C/G)tcaac intron-variant
rs3074776 -- 27,606,289(+) AGTTT(-/GATTT)ATGTA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF512 Gene

Variant ID Type Subtype PubMed ID
nsv817684 CNV Gain 17921354
esv2677128 CNV Deletion 23128226

Variation tolerance for ZNF512 Gene

Residual Variation Intolerance Score: 10.5% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.79; 16.72% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for ZNF512 Gene

Disorders for ZNF512 Gene

Relevant External Links for ZNF512

Genetic Association Database (GAD)
ZNF512
Human Genome Epidemiology (HuGE) Navigator
ZNF512
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ZNF512

No disorders were found for ZNF512 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF512 Gene

Publications for ZNF512 Gene

  1. Prediction of the coding sequences of unidentified human genes. XX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PMID: 11347906) Nagase T. … Ohara O. (DNA Res. 2001) 2 3 4 67
  2. Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes. (PMID: 25281560) Lambert J.P. … Gingras A.C. (J Proteomics 2015) 3
  3. Interactions of the Antiviral Factor Interferon Gamma-Inducible Protein 16 (IFI16) Mediate Immune Signaling and Herpes Simplex Virus-1 Immunosuppression. (PMID: 25693804) Diner B.A. … Cristea I.M. (Mol. Cell Proteomics 2015) 3
  4. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3
  5. A human interactome in three quantitative dimensions organized by stoichiometries and abundances. (PMID: 26496610) Hein M.Y. … Mann M. (Cell 2015) 3

Products for ZNF512 Gene

Sources for ZNF512 Gene

Content