ZNF512 Gene
protein-coding GIFtS: 41
GCID: GC02P027805
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|
zinc finger protein 512
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Aliases
for ZNF512 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Zinc Finger Protein 5121 2 | | KIAA18051 3 |
Export aliases for ZNF512 gene to outside databasesPrevious GC identifers: GC02P027780 GC02P027717 GC02P027659 GC02P027547 |
Summaries
for ZNF512 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for ZNF512:
This gene encodes a protein containing four putative zinc finger motifs. Zinc finger motifs may bind to proteins ornucleic acids. Zinc finger-containing proteins are involved in a variety of processes, including regulation oftranscription. Alternative splicing results in multiple transcript variants for this gene. (provided by RefSeq, Sep2012)
UniProtKB/Swiss-Prot: ZN512_HUMAN, Q96ME7Function: May be involved in transcriptional regulation
|
Genomic Views
for ZNF512 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000002.11 NC_018913.1 NT_022184.15
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the ZNF512 gene promoter:
STAT5B USF1 Sox5 AML1a FOXD1 XBP-1 LCR-F1 Cdc5 PPAR-gamma1 PPAR-gamma2
Other transcription factors
Search SABiosciences Chromatin IP Primers for ZNF512
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZNF512 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 2p23 Ensembl cytogenetic band: 2p23.3 HGNC cytogenetic band: 2p23ZNF512 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 2 GeneLoc Exon Structure GeneLoc location for GC02P027805: view genomic region
(about GC identifiers)
Start:
|
27,805,893 bp from pter |
End:
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27,858,041 bp from pter |
Size:
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52,149 bases |
Orientation:
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plus strand |
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Proteins
for ZNF512 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: ZN512_HUMAN, Q96ME7 (See
protein sequence)Recommended Name: Zinc finger protein 512 Size: 567 amino acids; 64682 Da
Subcellular location: Nucleus (Potential)
1 PDB 3D structure from  and Proteopedia  for ZNF512:2CTD (3D)
Secondary accessions: Q53RZ7 Q96JM0Explore the universe of human proteins at neXtProt for ZNF512: NX_Q96ME7
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q96ME7
ZNF512 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (6 alternative transcripts):
NP_001258215.1 NP_001258216.1 NP_001258217.1 NP_001258218.1 NP_001258247.1 NP_115810.2
ENSEMBL proteins: ENSP00000369040 ENSP00000347648 ENSP00000407038 ENSP00000395660 ENSP00000451572
Human Recombinant Protein Products for ZNF512:
Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table
ZNF512 for ontologies About GeneDecksing
ZNF512 Antibody Products:
Assay Products for ZNF512: |
Protein
Domains /
Families
for ZNF512 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ZNF512 for domains About GeneDecksing
2 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q96ME7ProtoNet protein and cluster: Q96ME7 UniProtKB/Swiss-Prot: ZN512_HUMAN, Q96ME7Similarity: Belongs to the krueppel C2H2-type zinc-finger protein familySimilarity: Contains 4 C2H2-type zinc fingers |
Function
for ZNF512 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Molecular Function:
UniProtKB/Swiss-Prot Summary: ZN512_HUMAN, Q96ME7Function: May be involved in transcriptional regulation Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table
ZNF512 for ontologies About GeneDecksing
Phenotypes:
2 GenomeRNAi human phenotypes for ZNF512:
Animal Models:
Clone
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OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF512
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: ZNF512 (NM_020713) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ZNF512 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF512 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF512 |
|
Pathways & Interactions
for ZNF512 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ZNF512
Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006351 | transcription, DNA-dependent |
IEA | -- | | GO:0006355 | regulation of transcription, DNA-dependent |
IEA | -- |
ZNF512 for ontologies About GeneDecksing
|
Drugs & Compounds
for ZNF512 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for ZNF512
Search CenterWatch for drugs/clinical trials and news about ZNF512 / ZN512
|
Transcripts
for ZNF512 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for ZNF512 gene (6 alternative transcripts): NM_001271286.1 NM_001271287.1 NM_001271288.1 NM_001271289.1 NM_001271318.1 NM_032434.3 Unigene Cluster for ZNF512: Zinc finger protein 512 Hs.529178 [show with all ESTs]Unigene Representative Sequence: NM_0012713188 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000379717 ENST00000355467(uc010ylw.2 uc002rlb.3 uc010ylx.2 uc002rlc.3 uc002rla.3 uc010ylv.2 uc010ylz.2)
ENST00000494548 ENST00000461705 ENST00000488055 ENST00000416005 ENST00000413371
ENST00000556601
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF512 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF512
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: ZNF512 (NM_020713) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ZNF512 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF512 |
Additional cDNA sequence: AB058708.1 AK057028.1 AK293771.1 AK294055.1 AK299818.1 AK316011.1 AK316299.1 AL833748.1 BC015707.1 BC043221.2 BC093041.1 BX647996.1 12 DOTS entries: DT.116138 DT.121010758 DT.95173172 DT.121010677 DT.95173176 DT.95206056 DT.95302977 DT.121010770 DT.97813177 DT.100025195 DT.443941 DT.95173171 24/195 AceView cDNA sequences (see all 195): BQ215308 BE503175 BM782796 AL136898 N39719 BE220056 BI861228 BM717631 AW955248 AA292267 BE669524 AW016695 BU508484 BU782559 AL833748 CR749335 AW189183 AI768018 AA306083 BQ478203 BM970272 CD652891 BG057669 NM_032266
GeneLoc Exon Structure
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Expression
for ZNF512 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ZNF512 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GTATATGCAC
About this image
See ZNF512 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for ZNF512
SOURCE GeneReport for Unigene cluster: Hs.529178
SABiosciences Custom PCR Arrays for ZNF512
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZNF512
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat ZNF512 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZNF512 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZNF512 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF512 |
Orthologs
for ZNF512 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for ZNF512 gene from 3/11 species (see all 11) About this table
ENSEMBL Gene Tree for ZNF512 (if available)
TreeFam Gene Tree for ZNF512 (if available) |
Paralogs
for ZNF512 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for ZNF512 gene
- ZNF512B2
2 SIMAP similar genes for ZNF512 using alignment to 5 protein entries: ZN512_HUMAN (see all proteins):DKFZp666L156 ZNF512B
ZNF512 for paralogs About GeneDecksing
|
Genomic Variants
for ZNF512 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 2 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for ZNF512 (27805893 - 27858041 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for ZNF512
1 CNV: 9400 | SABiosciences Cancer Mutation PCR Assays |
|
Disorders
/ Diseases
for ZNF512 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
 ZNF512 for disorders About MalaCards
ZNF512 for disorders About GeneDecksing
Human Genome Epidemiology (HuGE) Navigator: ZNF512 (1 document)
Export disorders for ZNF512 gene to outside databases
|
Publications
for ZNF512 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ZNF512 gene, integrated from 9 sources (see all 12):
(articles sorted by number of sources associating them with ZNF512) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Prediction of the coding sequences of unidentified human genes. XX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 11347906)1, 2, 3 Nagase T.... Ohara O. (2001)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Functional proteomics establishes the interaction of S IRT7 with chromatin remodeling complexes and expands its role in regulation of R NA polymerase I transcription. (PubMed id 22586326)1 Tsai Y.C....Cristea I.M. (2012)
- Genome-wide association study identifies novel loci as sociated with circulating phospho- and sphingolipid concentrations. (PubMed id 22359512)1 Demirkan A....Schmitz G. (2012)
- A bivariate genome-wide approach to metabolic syndrom e: STAMPEED consortium. (PubMed id 21386085)1 Kraja A.T....Borecki I.B. (2011)
- Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)
- Generalist genes analysis of DNA markers associated w ith mathematical ability and disability reveals shared influence across ages an d abilities. (PubMed id 20602751)1 Docherty S.J....Plomin R. (2010)
- In vitro nuclear interactome of the HIV-1 Tat protein . (PubMed id 19454010)1 Gautier V.W....Hall W.W. (2009)
- Sticky fingers: zinc-fingers as protein-recognition m otifs. (PubMed id 17210253)1 Gamsjaeger R....Mackay J.P. (2007)
- Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PubMed id 15815621)2 Hillier L.W....Wilson R.K. (2005)
|
External Searches for ZNF512 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing ZNF512 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing ZNF512 gene
(According to HUGE)
About This Section
| |
Specialized Databases showing ZNF512 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for ZNF512 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for ZNF512 gene:
Search GeneIP for patents involving ZNF512
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for ZNF512 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | Browse OriGene shRNA RFPs | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ZNF512 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZNF512 | | | OriGene Protein Over-expression Lysate for ZNF512 | | Browse OriGene Fluorogenic Cell Assay Kits | | | Browse OriGene siRNAs | | OriGene 3'-UTR Clone for ZNF512 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF512 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF512 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ZNF512 | | | Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ZNF512 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZNF512 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ZNF512 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZNF512 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZNF512 |
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| | | | Search Tocris compounds for ZNF512 |
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 | | | ZNF512 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF512 |
|  |  |  |  | | | | Search ThermoFisher Antibodies for ZNF512 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF512 |
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