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Aliases for ZNF507 Gene

Aliases for ZNF507 Gene

  • Zinc Finger Protein 507 2 3 5
  • KIAA1084 4

External Ids for ZNF507 Gene

Previous GeneCards Identifiers for ZNF507 Gene

  • GC19P037528
  • GC19P037433
  • GC19P032836
  • GC19P029339

Summaries for ZNF507 Gene

GeneCards Summary for ZNF507 Gene

ZNF507 (Zinc Finger Protein 507) is a Protein Coding gene. GO annotations related to this gene include nucleic acid binding.

UniProtKB/Swiss-Prot for ZNF507 Gene

  • May be involved in transcriptional regulation.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF507 Gene

Genomics for ZNF507 Gene

Regulatory Elements for ZNF507 Gene

Promoters for ZNF507 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around ZNF507 on UCSC Golden Path with GeneCards custom track

Genomic Location for ZNF507 Gene

Chromosome:
19
Start:
32,345,594 bp from pter
End:
32,387,667 bp from pter
Size:
42,074 bases
Orientation:
Plus strand

Genomic View for ZNF507 Gene

Genes around ZNF507 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF507 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF507 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF507 Gene

Proteins for ZNF507 Gene

  • Protein details for ZNF507 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8TCN5-ZN507_HUMAN
    Recommended name:
    Zinc finger protein 507
    Protein Accession:
    Q8TCN5
    Secondary Accessions:
    • A8K911
    • Q2TBF1
    • Q6MZU0
    • Q9UPR8

    Protein attributes for ZNF507 Gene

    Size:
    953 amino acids
    Molecular mass:
    105767 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAA83036.2; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=CAD28536.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=CAD28536.1; Type=Frameshift; Positions=56; Evidence={ECO:0000305}; Sequence=CAE45937.1; Type=Erroneous initiation; Evidence={ECO:0000305};

    Alternative splice isoforms for ZNF507 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZNF507 Gene

Proteomics data for ZNF507 Gene at MOPED

Post-translational modifications for ZNF507 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF507 Gene

No data available for DME Specific Peptides for ZNF507 Gene

Domains & Families for ZNF507 Gene

Gene Families for ZNF507 Gene

Protein Domains for ZNF507 Gene

Suggested Antigen Peptide Sequences for ZNF507 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q8TCN5

UniProtKB/Swiss-Prot:

ZN507_HUMAN :
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 9 C2H2-type zinc fingers.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 9 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF507: view

Function for ZNF507 Gene

Molecular function for ZNF507 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.
genes like me logo Genes that share phenotypes with ZNF507: view

Animal Model Products

CRISPR Products

miRNA for ZNF507 Gene

miRTarBase miRNAs that target ZNF507

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF507 Gene

Localization for ZNF507 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF507 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF507 Gene COMPARTMENTS Subcellular localization image for ZNF507 gene
Compartment Confidence
nucleus 5
cytosol 2

No data available for Gene Ontology (GO) - Cellular Components for ZNF507 Gene

Pathways & Interactions for ZNF507 Gene

SuperPathways for ZNF507 Gene

No Data Available

Interacting Proteins for ZNF507 Gene

Gene Ontology (GO) - Biological Process for ZNF507 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF507: view

No data available for Pathways by source and SIGNOR curated interactions for ZNF507 Gene

Drugs & Compounds for ZNF507 Gene

No Compound Related Data Available

Transcripts for ZNF507 Gene

Unigene Clusters for ZNF507 Gene

Zinc finger protein 507:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF507 Gene

ExUns: 1 ^ 2 ^ 3 ^ 4a · 4b ^ 5 ^ 6 ^ 7
SP1: - -
SP2:

Relevant External Links for ZNF507 Gene

GeneLoc Exon Structure for
ZNF507
ECgene alternative splicing isoforms for
ZNF507

Expression for ZNF507 Gene

mRNA expression in normal human tissues for ZNF507 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MOPED, and MaxQB for ZNF507 Gene



SOURCE GeneReport for Unigene cluster for ZNF507 Gene Hs.205392

genes like me logo Genes that share expression patterns with ZNF507: view

Protein tissue co-expression partners for ZNF507 Gene

- Elite partner

Primer Products

In Situ Assay Products

No data available for mRNA differential expression in normal tissues , Protein differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ZNF507 Gene

Orthologs for ZNF507 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZNF507 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia ZNF507 35
  • 87.99 (n)
  • 88.83 (a)
ZNF507 36
  • 88 (a)
OneToOne
dog
(Canis familiaris)
Mammalia ZNF507 35
  • 87.37 (n)
  • 89.72 (a)
ZNF507 36
  • 90 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Zfp507 35
  • 80.69 (n)
  • 80.94 (a)
Zfp507 16
Zfp507 36
  • 81 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia ZNF507 35
  • 99.51 (n)
  • 99.69 (a)
ZNF507 36
  • 99 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Zfp507 35
  • 80.38 (n)
  • 81.41 (a)
oppossum
(Monodelphis domestica)
Mammalia ZNF507 36
  • 72 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia ZNF507 36
  • 72 (a)
OneToOne
chicken
(Gallus gallus)
Aves ZNF507 35
  • 69.34 (n)
  • 63.89 (a)
ZNF507 36
  • 62 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia ZNF507 36
  • 60 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia znf507 35
  • 62.09 (n)
  • 57.51 (a)
African clawed frog
(Xenopus laevis)
Amphibia Xl.32184 35
zebrafish
(Danio rerio)
Actinopterygii znf507 35
  • 53.06 (n)
  • 49.23 (a)
ZNF507 36
  • 17 (a)
OneToOne
Species with no ortholog for ZNF507:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ZNF507 Gene

ENSEMBL:
Gene Tree for ZNF507 (if available)
TreeFam:
Gene Tree for ZNF507 (if available)

Paralogs for ZNF507 Gene

(9) SIMAP similar genes for ZNF507 Gene using alignment to 3 proteins:

genes like me logo Genes that share paralogs with ZNF507: view

No data available for Paralogs for ZNF507 Gene

Variants for ZNF507 Gene

Sequence variations from dbSNP and Humsavar for ZNF507 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
rs12596 -- 32,386,219(+) TTGAA(A/G)GTGGC utr-variant-3-prime
rs741444 -- 32,345,018(+) TCATA(A/G)AACAG upstream-variant-2KB
rs741445 -- 32,345,686(-) CCCGG(A/C)TCTTT utr-variant-5-prime
rs741446 -- 32,345,900(-) GCACC(A/G)GGCGG intron-variant
rs1468919 -- 32,368,984(+) AAAGT(G/T)GGGGG intron-variant

Variation tolerance for ZNF507 Gene

Residual Variation Intolerance Score: 2.58% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.89; 35.27% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ZNF507 Gene

HapMap Linkage Disequilibrium report
ZNF507

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for ZNF507 Gene

Disorders for ZNF507 Gene

Relevant External Links for ZNF507

Genetic Association Database (GAD)
ZNF507
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ZNF507

No disorders were found for ZNF507 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF507 Gene

Publications for ZNF507 Gene

  1. Prediction of the coding sequences of unidentified human genes. XIV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PMID: 10470851) Kikuno R. … Ohara O. (DNA Res. 1999) 3 4 67
  2. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3
  3. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  4. Large-scale characterization of HeLa cell nuclear phosphoproteins. (PMID: 15302935) Beausoleil S.A. … Gygi S.P. (Proc. Natl. Acad. Sci. U.S.A. 2004) 3
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for ZNF507 Gene

Sources for ZNF507 Gene

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