Free for academic non-profit institutions. Other users need a Commercial license

Aliases for ZNF506 Gene

Aliases for ZNF506 Gene

  • Zinc Finger Protein 506 2 3

External Ids for ZNF506 Gene

Summaries for ZNF506 Gene

GeneCards Summary for ZNF506 Gene

ZNF506 (Zinc Finger Protein 506) is a Protein Coding gene. Among its related pathways are Gene Expression and Gene Expression. An important paralog of this gene is ZNF253.

UniProtKB/Swiss-Prot for ZNF506 Gene

  • May be involved in transcriptional regulation

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF506 Gene

Genomics for ZNF506 Gene

Genomic Location for ZNF506 Gene

Start:
19,785,839 bp from pter
End:
19,821,751 bp from pter
Size:
35,913 bases
Orientation:
Minus strand

Genomic View for ZNF506 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZNF506 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF506 Gene

Regulatory Elements for ZNF506 Gene

Proteins for ZNF506 Gene

  • Protein details for ZNF506 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q5JVG8-ZN506_HUMAN
    Recommended name:
    Zinc finger protein 506
    Protein Accession:
    Q5JVG8
    Secondary Accessions:
    • B3KTH6

    Protein attributes for ZNF506 Gene

    Size:
    444 amino acids
    Molecular mass:
    51537 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ZNF506 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZNF506 Gene

Proteomics data for ZNF506 Gene at MOPED

Post-translational modifications for ZNF506 Gene

  • Modification sites at PhosphoSitePlus
  • Ubiquitination at Lys97 and Lys320

No data available for DME Specific Peptides for ZNF506 Gene

Domains for ZNF506 Gene

Gene Families for ZNF506 Gene

HGNC:
  • ZNF :Zinc fingers, C2H2-type

UniProtKB/Swiss-Prot:

ZN506_HUMAN
Domain:
  • Contains 1 KRAB domain.:
    • Q5JVG8
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.:
    • Q5JVG8
Similarity:
  • Contains 8 C2H2-type zinc fingers.:
    • Q5JVG8
genes like me logo Genes that share domains with ZNF506: view

Function for ZNF506 Gene

Molecular function for ZNF506 Gene

UniProtKB/Swiss-Prot Function: May be involved in transcriptional regulation

Gene Ontology (GO) - Molecular Function for ZNF506 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding --
GO:0003677 DNA binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF506: view

Phenotypes for ZNF506 Gene

GenomeRNAi human phenotypes for ZNF506:
genes like me logo Genes that share phenotypes with ZNF506: view

miRNA for ZNF506 Gene

miRTarBase miRNAs that target ZNF506

No data available for Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for ZNF506 Gene

Localization for ZNF506 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF506 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF506 Gene COMPARTMENTS Subcellular localization image for ZNF506 gene
Compartment Confidence
nucleus 4

Gene Ontology (GO) - Cellular Components for ZNF506 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular --
GO:0005730 nucleolus IDA --
genes like me logo Genes that share ontologies with ZNF506: view

Pathways for ZNF506 Gene

SuperPathways for ZNF506 Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF506: view

Pathways by source for ZNF506 Gene

2 Reactome pathways for ZNF506 Gene

Gene Ontology (GO) - Biological Process for ZNF506 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF506: view

Transcripts for ZNF506 Gene

Unigene Clusters for ZNF506 Gene

Zinc finger protein 506:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF506 Gene

No ASD Table

Relevant External Links for ZNF506 Gene

GeneLoc Exon Structure for
ZNF506
ECgene alternative splicing isoforms for
ZNF506

Expression for ZNF506 Gene

mRNA expression in normal human tissues for ZNF506 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for ZNF506 Gene

SOURCE GeneReport for Unigene cluster for ZNF506 Gene Hs.351906

genes like me logo Genes that share expressions with ZNF506: view

Orthologs for ZNF506 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZNF506 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF506 36
  • 99.17 (n)
  • 98.42 (a)
ZNF506 37
  • 98 (a)
OneToOne
cow
(Bos Taurus)
Mammalia -- 37
  • 41 (a)
OneToMany
dog
(Canis familiaris)
Mammalia -- 37
  • 29 (a)
OneToMany
mouse
(Mus musculus)
Mammalia Zfp386 37
  • 30 (a)
OneToMany
Zfp71-rs1 16
oppossum
(Monodelphis domestica)
Mammalia -- 37
  • 29 (a)
ManyToMany
-- 37
  • 43 (a)
ManyToMany
lizard
(Anolis carolinensis)
Reptilia -- 37
  • 37 (a)
ManyToMany
-- 37
  • 25 (a)
ManyToMany
-- 37
  • 30 (a)
ManyToMany
-- 37
  • 30 (a)
ManyToMany
-- 37
  • 23 (a)
ManyToMany
-- 37
  • 22 (a)
ManyToMany
-- 37
  • 22 (a)
ManyToMany
-- 37
  • 22 (a)
ManyToMany
Species with no ortholog for ZNF506:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF506 Gene

ENSEMBL:
Gene Tree for ZNF506 (if available)
TreeFam:
Gene Tree for ZNF506 (if available)

Paralogs for ZNF506 Gene

Selected SIMAP similar genes for ZNF506 Gene using alignment to 8 proteins:

Pseudogenes.org Pseudogenes for ZNF506 Gene

genes like me logo Genes that share paralogs with ZNF506: view

Variants for ZNF506 Gene

Sequence variations from dbSNP and Humsavar for ZNF506 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type MAF
rs4808996 -- 19,817,433(+) aatct(A/G)atttt intron-variant
rs7250144 -- 19,821,082(+) tttag(C/T)agaca intron-variant
rs9676800 -- 19,818,857(+) GTGGC(A/G)GGCAC intron-variant
rs10404296 -- 19,816,884(+) gcgcc(A/G)tcttg intron-variant
rs10411953 -- 19,817,940(+) ctcct(A/C/G)cctca intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF506 Gene

Variant ID Type Subtype PubMed ID
dgv3790n71 CNV Gain 21882294
nsv458375 CNV Gain 19166990
dgv3791n71 CNV Loss 21882294
nsv519535 CNV Gain 19592680
esv2669979 CNV Deletion 23128226
esv2718296 CNV Deletion 23290073
esv2665024 CNV Deletion 23128226

Relevant External Links for ZNF506 Gene

HapMap Linkage Disequilibrium report
ZNF506

Disorders for ZNF506 Gene

No disorders were found for ZNF506 Gene.

No data available for UniProtKB/Swiss-Prot for ZNF506 Gene

Publications for ZNF506 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  2. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  3. PML-associated repressor of transcription (PAROT), a novel KRAB-zinc finger repressor, is regulated through association with PML nuclear bodies. (PMID: 16412420) Fleischer S. … Hofmann T.G. (Exp. Cell Res. 2006) 3
  4. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PMID: 21890473) Wagner S.A. … Choudhary C. (Mol. Cell Proteomics 2011) 3
  5. Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition. (PMID: 22505724) Udeshi N.D. … Carr S.A. (Mol. Cell Proteomics 2012) 3

Products for ZNF506 Gene

Sources for ZNF506 Gene

Back to Top

Content