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Aliases for ZNF502 Gene

Aliases for ZNF502 Gene

  • Zinc Finger Protein 502 2 3 5

External Ids for ZNF502 Gene

Previous GeneCards Identifiers for ZNF502 Gene

  • GC03P044714
  • GC03P044559
  • GC03P044729
  • GC03P044754
  • GC03P044756
  • GC03P044833
  • GC03P044841

Summaries for ZNF502 Gene

GeneCards Summary for ZNF502 Gene

ZNF502 (Zinc Finger Protein 502) is a Protein Coding gene. An important paralog of this gene is ZNF665.

UniProtKB/Swiss-Prot for ZNF502 Gene

  • May be involved in transcriptional regulation.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF502 Gene

Genomics for ZNF502 Gene

Regulatory Elements for ZNF502 Gene

Enhancers for ZNF502 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH03F044233 1.3 Ensembl ENCODE 20.2 -476.7 -476741 5.6 PKNOX1 ATF1 ARNT BRCA1 ELK1 GATA2 ZNF143 FOS JUNB REST ZNF660 ZNF502 ZKSCAN7 RNU6-367P ZNF35 SNRK-AS1 MIR138-1 ZNF197 TCAIM ENSG00000271941
GH03F045130 1.7 FANTOM5 Ensembl ENCODE 14.1 +423.3 423349 11.1 HDGF PKNOX1 ARNT CREB3L1 SIN3A FEZF1 CBX5 FOS KLF13 JUNB SACM1L ZNF660 ZNF502 ENSG00000272077 LINC00694 ZNF197-AS1 ZKSCAN7 ZNF501 RNU5B-3P CLEC3B
GH03F044860 1 ENCODE 18.6 +149.3 149340 2.1 ATF1 ZFP64 SIN3A ARID4B DMAP1 ZNF48 YY1 ZNF121 GLIS2 ZNF143 ZNF502 TMEM42 GC03P044947 PPIAP18
GH03F044712 0.9 ENCODE 20.1 0.0 -10 1.2 CBX3 ATF1 TBL1XR1 ZNF76 SIN3A RAD21 ZBTB40 ETS1 YY1 ZNF143 ZNF502 SOCS5P3
GH03F045653 1.2 Ensembl ENCODE 13.9 +942.7 942718 4.3 HDGF PKNOX1 WRNIP1 ARID4B SIN3A DMAP1 ZNF2 GLIS2 ZNF143 ZNF548 SACM1L LIMD1 ZNF502 RN7SL145P LARS2-AS1 LIMD1-AS1 CCR3 GC03M045664 PIR32515
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around ZNF502 on UCSC Golden Path with GeneCards custom track

Promoters for ZNF502 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00001362513 258 1399 CBX3 ATF1 TBL1XR1 ZNF76 SIN3A RAD21 ZBTB40 ETS1 YY1 CREM

Genomic Location for ZNF502 Gene

Chromosome:
3
Start:
44,712,643 bp from pter
End:
44,723,831 bp from pter
Size:
11,189 bases
Orientation:
Plus strand

Genomic View for ZNF502 Gene

Genes around ZNF502 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF502 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF502 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF502 Gene

Proteins for ZNF502 Gene

  • Protein details for ZNF502 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8TBZ5-ZN502_HUMAN
    Recommended name:
    Zinc finger protein 502
    Protein Accession:
    Q8TBZ5

    Protein attributes for ZNF502 Gene

    Size:
    544 amino acids
    Molecular mass:
    62920 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZNF502 Gene

Post-translational modifications for ZNF502 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for ZNF502 Gene

Domains & Families for ZNF502 Gene

Gene Families for ZNF502 Gene

Protein Domains for ZNF502 Gene

Suggested Antigen Peptide Sequences for ZNF502 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q8TBZ5

UniProtKB/Swiss-Prot:

ZN502_HUMAN :
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 14 C2H2-type zinc fingers.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 14 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF502: view

Function for ZNF502 Gene

Molecular function for ZNF502 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Gene Ontology (GO) - Molecular Function for ZNF502 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding IBA --
GO:0003676 nucleic acid binding IEA --
GO:0003677 DNA binding IEA --
GO:0005515 protein binding IPI 25416956
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF502: view
genes like me logo Genes that share phenotypes with ZNF502: view

Animal Model Products

Inhibitory RNA Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF502 Gene

Localization for ZNF502 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF502 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZNF502 gene
Compartment Confidence
nucleus 5
cytosol 2

Gene Ontology (GO) - Cellular Components for ZNF502 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IDA 25556234
genes like me logo Genes that share ontologies with ZNF502: view

Pathways & Interactions for ZNF502 Gene

SuperPathways for ZNF502 Gene

No Data Available

Gene Ontology (GO) - Biological Process for ZNF502 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA,IBA --
GO:0044791 positive regulation by host of viral release from host cell IMP 25556234
GO:0044794 positive regulation by host of viral process IMP 25556234
genes like me logo Genes that share ontologies with ZNF502: view

No data available for Pathways by source and SIGNOR curated interactions for ZNF502 Gene

Transcripts for ZNF502 Gene

Unigene Clusters for ZNF502 Gene

Zinc finger protein 502:
Representative Sequences:

Inhibitory RNA Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF502 Gene

ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5a · 5b · 5c · 5d · 5e
SP1:
SP2: -
SP3: -
SP4: - -
SP5: - -

Relevant External Links for ZNF502 Gene

GeneLoc Exon Structure for
ZNF502
ECgene alternative splicing isoforms for
ZNF502

Expression for ZNF502 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for ZNF502 Gene

Protein differential expression in normal tissues from HIPED for ZNF502 Gene

This gene is overexpressed in Fetal testis (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for ZNF502 Gene



Protein tissue co-expression partners for ZNF502 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of ZNF502 Gene:

ZNF502

SOURCE GeneReport for Unigene cluster for ZNF502 Gene:

Hs.224843
genes like me logo Genes that share expression patterns with ZNF502: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ZNF502 Gene

Orthologs for ZNF502 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZNF502 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF502 34 35
  • 99.45 (n)
dog
(Canis familiaris)
Mammalia ZNF502 34 35
  • 91.68 (n)
cow
(Bos Taurus)
Mammalia ZNF502 34 35
  • 90.66 (n)
rat
(Rattus norvegicus)
Mammalia LOC100911237 34
  • 67.03 (n)
mouse
(Mus musculus)
Mammalia Zfp72 34 16
  • 65.42 (n)
oppossum
(Monodelphis domestica)
Mammalia ZNF502 35
  • 63 (a)
OneToOne
chicken
(Gallus gallus)
Aves -- 35
  • 49 (a)
OneToMany
Species where no ortholog for ZNF502 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF502 Gene

ENSEMBL:
Gene Tree for ZNF502 (if available)
TreeFam:
Gene Tree for ZNF502 (if available)

Paralogs for ZNF502 Gene

(471) SIMAP similar genes for ZNF502 Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with ZNF502: view

Variants for ZNF502 Gene

Sequence variations from dbSNP and Humsavar for ZNF502 Gene

SNP ID Clin Chr 03 pos Sequence Context AA Info Type
rs1062342 -- 44,722,799(+) TTCGT(C/T)GGCTG intron-variant, utr-variant-3-prime
rs10626737 -- 44,722,977(+) GAGCC(-/A/AA)AAAAA intron-variant, utr-variant-3-prime
rs10639664 -- 44,723,816(+) AACAC(-/T)TAAGT intron-variant, downstream-variant-500B, utr-variant-3-prime
rs10674776 -- 44,723,866(+) TTTTT(-/GTTTTA/GTTTTG)TGTTT intron-variant, downstream-variant-500B
rs111578147 -- 44,718,380(+) ATTAT(A/C)TGTTG intron-variant, nc-transcript-variant, upstream-variant-2KB

Variation tolerance for ZNF502 Gene

Residual Variation Intolerance Score: 50.6% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 5.95; 74.58% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ZNF502 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ZNF502

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for ZNF502 Gene

Disorders for ZNF502 Gene

Relevant External Links for ZNF502

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ZNF502

No disorders were found for ZNF502 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF502 Gene

Publications for ZNF502 Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 64
  2. New host factors important for respiratory syncytial virus (RSV) replication revealed by a novel microfluidics screen for interactors of matrix (M) protein. (PMID: 25556234) Kipper S. … Bajorek M. (Mol. Cell Proteomics 2015) 3 64
  3. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3 64
  4. An atlas of combinatorial transcriptional regulation in mouse and man. (PMID: 20211142) Ravasi T. … Hayashizaki Y. (Cell 2010) 3 64
  5. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3 64

Products for ZNF502 Gene

Sources for ZNF502 Gene

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