ZNF502 Gene
protein-coding GIFtS: 43
GCID: GC03P044754
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|
zinc finger protein 502
| |
Aliases
for ZNF502 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Zinc Finger Protein 5021 2 | | FLJ125151 | | FLJ148551 |
Export aliases for ZNF502 gene to outside databasesPrevious GC identifers: GC03P044714 GC03P044559 GC03P044729 |
Summaries
for ZNF502 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
UniProtKB/Swiss-Prot: ZN502_HUMAN, Q8TBZ5Function: May be involved in transcriptional regulation
|
Genomic Views
for ZNF502 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000003.11 NC_018914.1 NT_022517.18
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the ZNF502 gene promoter:
Nkx3-1 TBP Nkx3-1 v4 FOXD3 Nkx3-1 v1 Ik-3 Nkx3-1 v2 TFIID Sox9 Nkx3-1 v3
Other transcription factors
Search SABiosciences Chromatin IP Primers for ZNF502
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZNF502 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 3p21.31 Ensembl cytogenetic band: 3p21.31 HGNC cytogenetic band: 3p21.32ZNF502 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 3 GeneLoc Exon Structure GeneLoc location for GC03P044754: view genomic region
(about GC identifiers)
Start:
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44,754,135 bp from pter |
End:
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44,765,323 bp from pter |
Size:
|
11,189 bases |
Orientation:
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plus strand |
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Proteins
for ZNF502 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: ZN502_HUMAN, Q8TBZ5 (See
protein sequence)Recommended Name: Zinc finger protein 502 Size: 544 amino acids; 62920 Da
Subcellular location: Nucleus (Potential)Explore the universe of human proteins at neXtProt for ZNF502: NX_Q8TBZ5
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q8TBZ5
ZNF502 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (4 alternative transcripts):
NP_001127912.1 NP_001127913.1 NP_001127914.1 NP_149987.2
ENSEMBL proteins: ENSP00000296091 ENSP00000406469 ENSP00000401717 ENSP00000397390
Human Recombinant Protein Products:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005634 | nucleus |
IEA | -- |
ZNF502 for ontologies About GeneDecksing
ZNF502 Antibody Products:
Assay Products for ZNF502: |
Protein
Domains /
Families
for ZNF502 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ZNF502 for domains About GeneDecksing
3 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q8TBZ5ProtoNet protein and cluster: Q8TBZ5 1 Blocks protein family: IPB007086 C2H2-type zinc finger signature
UniProtKB/Swiss-Prot: ZN502_HUMAN, Q8TBZ5Similarity: Belongs to the krueppel C2H2-type zinc-finger protein familySimilarity: Contains 14 C2H2-type zinc fingers |
Function
for ZNF502 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: ZN502_HUMAN, Q8TBZ5Function: May be involved in transcriptional regulation
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF502 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF502 (see all 4)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
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| |  | GenScript: all cDNA clones in your preferred vector (see all 4): ZNF502 (NM_001134441) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ZNF502 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF502 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF502 |
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table
ZNF502 for ontologies About GeneDecksing
|
Pathways & Interactions
for ZNF502 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ZNF502
STRING Interaction
Network Preview (showing 1 interactants - click image to see more details)
1 Interacting protein for ZNF502 (Q8TBZ53 ENSP000002960914) via UniProtKB, MINT, STRING, and/or I2DAbout this table
Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006351 | transcription, DNA-dependent |
IEA | -- | | GO:0006355 | regulation of transcription, DNA-dependent |
IEA | -- |
ZNF502 for ontologies About GeneDecksing
|
Drugs & Compounds
for ZNF502 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for ZNF502
Search CenterWatch for drugs/clinical trials and news about ZNF502 / ZN502
|
Transcripts
for ZNF502 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for ZNF502 gene (4 alternative transcripts): NM_001134440.1 NM_001134441.1 NM_001134442.1 NM_033210.4 Unigene Cluster for ZNF502: Zinc finger protein 502 Hs.224843 [show with all ESTs]Unigene Representative Sequence: NM_0332104 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000296091(uc011baa.2 uc003cns.3) ENST00000436624 ENST00000411443
ENST00000449836(uc011bab.2 uc003cnt.3)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF502 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF502 (see all 4)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 4): ZNF502 (NM_001134441) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ZNF502 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF502 |
Additional cDNA sequence: AK022577.1 AK027761.1 BC028377.2 3 DOTS entries: DT.445583 DT.100752112 DT.100752113 24/44 AceView cDNA sequences (see all 44): AL041582 AA582385 AK022577 BQ021800 BX483171 AL041583 AA485156 AU124164 BM682170 BC028377 NM_033210 BM929990 BU569663 BP871373 AW293757 BM973066 AI000691 CD238398 BU679560 AI001056 CA429484 AI796772 AA058956 BQ428480
GeneLoc Exon Structure
5 Alternative Splicing Database (ASD) splice patterns (SP) for ZNF502 About this scheme
| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5a | · | 5b | · | 5c | · | 5d | · | 5e |
|---|
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| SP1: | | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | - | | | | | | | | | | | | | | |
| SP3: | | | | | | | - | | | | | | | | | | | | | | |
| SP4: | | | | | - | | - | | | | | | | | | | | | | | |
| SP5: | | | | | - | | - | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for ZNF502
|
Expression
for ZNF502 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ZNF502 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TTCTTAACTG
About this image
See ZNF502 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for ZNF502
SOURCE GeneReport for Unigene cluster: Hs.224843
SABiosciences Custom PCR Arrays for ZNF502
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZNF502
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat ZNF502 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZNF502 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZNF502 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF502 |
Orthologs
for ZNF502 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for ZNF502 gene from 3/9 species (see all 9) About this table
ENSEMBL Gene Tree for ZNF502 (if available)
TreeFam Gene Tree for ZNF502 (if available) |
Paralogs
for ZNF502 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for ZNF502 gene
- ZNF712 ZNF5862 ZNF5012 ZNF162 ZNF6232 ZFP22 ZNF3452 ZNF232
- ZNF8522 ZFP32 ZNF352 ZNF6602 ZKSCAN72
18/465 SIMAP similar genes for ZNF502 using alignment to 2 protein entries: ZN502_HUMAN (see all proteins)
(see all similar genes):ZNF829 HZF36 ZNF485 ZNF146 ZNF347 ZNF383
ZNF418 ZNF436 ZNF84 ZSCAN16 DKFZp666C237 DKFZp686D2168
HZF30 ZNF19 ZNF2 ZNF345 ZNF83 ZNF571
ZNF502 for paralogs About GeneDecksing
|
Genomic Variants
for ZNF502 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 3 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for ZNF502 (44754135 - 44765323 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for ZNF502: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ZNF502 |
|
Disorders
/ Diseases
for ZNF502 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications
for ZNF502 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ZNF502 gene integrated from 9 sources:
(articles sorted by number of sources associating them with ZNF502) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)
- An atlas of combinatorial transcriptional regulation in mouse and man. (PubMed id 20211142)1 Ravasi T....Hayashizaki Y. (2010)
- Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1 Ota T.... Sugano S. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
|
External Searches for ZNF502 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing ZNF502 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing ZNF502 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing ZNF502 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for ZNF502 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for ZNF502 gene:
Search GeneIP for patents involving ZNF502
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for ZNF502 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for ZNF502 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ZNF502 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ZNF502 | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for ZNF502 | | OriGene 3'-UTR Clone for ZNF502 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF502 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ZNF502 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for ZNF502 | | OriGene Custom Protein Services for ZNF502 | | | OriGene Custom Immunoassay Development | | |
| |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ZNF502 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ZNF502 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZNF502 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ZNF502 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZNF502 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZNF502 |
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 |  |  |  | |
| | | | Search Tocris compounds for ZNF502 |
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 | | | ZNF502 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF502 |
|  |  |  | | | | Search ThermoFisher Antibodies for ZNF502 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF502 |
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