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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

ZNF502 Gene

protein-coding   GIFtS: 43
GCID: GC03P044754

Zinc Finger Protein 502

  Search for ZNF502
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Zinc Finger Protein 5021 2

External Ids:    HGNC: 237181   Entrez Gene: 913922   Ensembl: ENSG000001966537   UniProtKB: Q8TBZ53   

Export aliases for ZNF502 gene to outside databases

Previous GC identifers: GC03P044714 GC03P044559 GC03P044729


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for ZNF502 Gene: 
ZNF502 (zinc finger protein 502) is a protein-coding gene. GO annotations related to this gene include DNA binding and zinc ion binding. An important paralog of this gene is ZNF436.

UniProtKB/Swiss-Prot: ZN502_HUMAN, Q8TBZ5
Function: May be involved in transcriptional regulation




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000003.11  NT_022517.18  NC_018914.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the ZNF502 gene promoter:
         Nkx3-1   TBP   Nkx3-1 v4   FOXD3   Nkx3-1 v1   Ik-3   Nkx3-1 v2   TFIID   Sox9   Nkx3-1 v3   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidZNF502 promoter sequence
   Search SABiosciences Chromatin IP Primers for ZNF502

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ZNF502


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 3p21.31   Ensembl cytogenetic band:  3p21.31   HGNC cytogenetic band: 3p21.32

ZNF502 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ZNF502 gene location

GeneLoc information about chromosome 3         GeneLoc Exon Structure

GeneLoc location for GC03P044754:  view genomic region     (about GC identifiers)

Start:
44,754,135 bp from pter      End:
44,765,323 bp from pter
Size:
11,189 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: ZN502_HUMAN, Q8TBZ5 (See protein sequence)
Recommended Name: Zinc finger protein 502  
Size: 544 amino acids; 62920 Da
Subcellular location: Nucleus (Potential)

Explore the universe of human proteins at neXtProt for ZNF502: NX_Q8TBZ5

Explore proteomics data for ZNF502 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q8TBZ5

  • ZNF502 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    ZNF502 Protein Expression
    REFSEQ proteins (5 alternative transcripts): 
    NP_001127912.1  NP_001127913.1  NP_001127914.1  NP_001269809.1  NP_149987.2  

    ENSEMBL proteins: 
     ENSP00000406469   ENSP00000296091   ENSP00000401717   ENSP00000397390  

    Human Recombinant Protein Products for ZNF502: 
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    Novus Biologicals ZNF502 Protein
    Novus Biologicals ZNF502 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for ZNF502 

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IEA--

    ZNF502 for ontologies           About GeneDecksing



    ZNF502 Antibody Products: 
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    LSBio Antibodies in human, mouse, rat for ZNF502 

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    Cloud-Clone Corp. ELISAs for ZNF502 
    Cloud-Clone Corp. CLIAs for ZNF502


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    ZNF: Zinc fingers, C2H2-type

    3 InterPro protein domains:
     IPR015880 Znf_C2H2-like
     IPR013087 Znf_C2H2/integrase_DNA-bd
     IPR007087 Znf_C2H2

    Graphical View of Domain Structure for InterPro Entry Q8TBZ5

    ProtoNet protein and cluster: Q8TBZ5

    1 Blocks protein domain: IPB007086 C2H2-type zinc finger signature

    UniProtKB/Swiss-Prot: ZN502_HUMAN, Q8TBZ5
    Similarity: Belongs to the krueppel C2H2-type zinc-finger protein family
    Similarity: Contains 14 C2H2-type zinc fingers


    ZNF502 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: ZN502_HUMAN, Q8TBZ5
    Function: May be involved in transcriptional regulation

         Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003677DNA binding IEA--
    GO:0008270zinc ion binding ----
    GO:0046872metal ion binding IEA--
         
    ZNF502 for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for ZNF502 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for ZNF502

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for ZNF502 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for ZNF502 

    miRNA
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    5 QIAGEN miScript miRNA Assays for microRNAs that regulate ZNF502:
    hsa-miR-875-3p hsa-miR-7-1* hsa-miR-7-2* hsa-miR-486-3p hsa-miR-1299
    SwitchGear 3'UTR luciferase reporter plasmidZNF502 3' UTR sequence
    Inhib. RNA
    Products:
        
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    Gene Editing
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    Clone
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    Cell Line
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    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF502


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ZNF502

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    1 Interacting protein for ZNF502 (Q8TBZ53 ENSP000002960914) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    TLX2O437633, ENSP000002336384I2D: score=1 STRING: ENSP00000233638
    About this table

    Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006351transcription, DNA-dependent IEA--
    GO:0006355regulation of transcription, DNA-dependent IEA--

    ZNF502 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for ZNF502 (ZN502)

    Search CenterWatch for drugs/clinical trials and news about ZNF502 / ZN502

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for ZNF502 gene (5 alternative transcripts): 
    NM_001134440.1  NM_001134441.1  NM_001134442.1  NM_001282880.1  NM_033210.4  

    Unigene Cluster for ZNF502:

    Zinc finger protein 502
    Hs.224843  [show with all ESTs]
    Unigene Representative Sequence: NM_033210
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000436624 ENST00000296091(uc011baa.2 uc003cns.3) ENST00000411443
    ENST00000449836(uc011bab.2 uc003cnt.3)
    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat ZNF502
    5 QIAGEN miScript miRNA Assays for microRNAs that regulate ZNF502:
    hsa-miR-875-3p hsa-miR-7-1* hsa-miR-7-2* hsa-miR-486-3p hsa-miR-1299
    SwitchGear 3'UTR luciferase reporter plasmidZNF502 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for ZNF502
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ZNF502
    Clone
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    OriGene clones in human, mouse for ZNF502 (see all 16)
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 4): ZNF502 (NM_001134441)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ZNF502
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF502
    Sirion Biotech Customized lentivirus for stable overexpression of ZNF502 
                         Customized lentivirus expression plasmids for stable overexpression of ZNF502 
    Primer
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    OriGene qSTAR qPCR primer pairs in human, mouse for ZNF502
    SABiosciences RT2 qPCR Primer Assay in human, mouse / rat ZNF502
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ZNF502
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ZNF502

    Additional mRNA sequence: 

    AK022577.1 AK027761.1 BC028377.2 

    3 DOTS entries:

    DT.445583  DT.100752112  DT.100752113 

    24/44 AceView cDNA sequences (see all 44):

    AL041582 NM_033210 AA485156 AL041583 AA582385 AU124164 BX483171 BM682170 
    BQ021800 AK022577 BC028377 BM929990 BP871373 AI609789 CA429484 AI000691 
    AI651870 AA058956 BU679560 AK027761 AI001056 CD238398 BU569663 BQ428480 

    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for ZNF502    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5a · 5b · 5c · 5d · 5e
    SP1:                                                            
    SP2:                    -                                       
    SP3:                    -                                       
    SP4:              -     -                                       
    SP5:              -     -                                       


    ECgene alternative splicing isoforms for ZNF502

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    ZNF502 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TTCTTAACTG
    ZNF502 Expression
    About this image


    See ZNF502 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for ZNF502

    SOURCE GeneReport for Unigene cluster: Hs.224843
        SABiosciences Custom PCR Arrays for ZNF502
    Primer
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF502

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for ZNF502 gene from 4/11 species (see all 11)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    chicken
    (Gallus gallus)
    Aves ZFP31 zinc finger protein 3 homolog (mouse) 60.74(n)
    57.14(a)
      427922  XM_425495.3  XP_425495.2 
    lizard
    (Anolis carolinensis)
    Reptilia --
    --
    (see all 7)
    Uncharacterized protein
    (see all 7)
    63(a)
    58(a)
    (see all 7)
    many ↔ many
    many ↔ many
    (see all 7)
    GL343312.1(8265-9200)
    AAWZ02041495(3704-5129)
    zebrafish
    (Danio rerio)
    Actinopterygii CR792418.16
    si:rp71-7l19.66
    (see all 11)
    si:rp71-7l19.6
    (see all 11)
    46(a)
    46(a)
    (see all 11)
    many ↔ many
    many ↔ many
    (see all 11)
    4(33542000-33543552)
    4(29214878-29224483)
    fruit fly
    (Drosophila melanogaster)
    Insecta CG122996
    --
    17(a)
    1 → many
    2L(10737345-10740762)
            Species with no ortholog for ZNF502

    ENSEMBL Gene Tree for ZNF502 (if available)
    TreeFam Gene Tree for ZNF502 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for ZNF502 gene
    ZNF4362  ZNF1802  ZNF3222  ZNF712  ZNF5722  ZFP22  ZNF6972  ZKSCAN72  
    ZNF6782  ZNF7742  ZNF102  ZFP372  ZSCAN22  ZNF8522  ZNF3292  ZNF5442  
    ZFP32  ZNF6062  ZNF8352  
    18/470 SIMAP similar genes for ZNF502 using alignment to 2 protein entries:     ZN502_HUMAN (see all proteins) (see all similar genes):
    ZNF829    HZF36    ZNF485    ZNF146    ZNF323    ZNF347
    ZNF383    ZNF418    ZNF436    ZNF84    ZSCAN16    DKFZp666C237
    DKFZp686D2168    HZF30    ZNF19    ZNF2    ZNF345    ZNF83

    ZNF502 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/302 SNPs in ZNF502 are shown (see all 302)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 3 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs67795031,2
    C,F,A,H--44682919(+) GACGGT/CTTTGG 4 -- us2k114Minor allele frequency- C:0.14NS EA WA NA CSA 1596
    rs1846479011,2
    --44682953(+) GCTGAC/TGTTTT 4 -- us2k10--------
    rs586493301,2
    C,F--44682958(+) TGTTTC/TTCTCT 4 -- us2k10--------
    rs126308301,2
    C,H--44683006(+) TTTCAC/GTACAG 4 -- us2k14Minor allele frequency- G:0.00NS EA 352
    rs1885703931,2
    --44683088(+) CATTGA/TTTATA 4 -- us2k10--------
    rs783898131,2
    C,F--44683111(+) GCGCAC/TGGGGC 4 -- us2k11Minor allele frequency- T:0.03NA 120
    rs1918418921,2
    --44683125(+) CTCATC/TCAGGA 4 -- us2k10--------
    rs1457828001,2
    --44683160(+) CTGGAC/TGGCGC 4 -- us2k10--------
    rs1836465981,2
    --44683217(+) CCTCCA/GACTGC 4 -- us2k10--------
    rs1161015391,2
    F--44683248(+) TCCTCC/TGGACT 4 -- us2k11Minor allele frequency- T:0.04WA 118

    HapMap Linkage Disequilibrium report for ZNF502 (44754135 - 44765323 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for ZNF502: --
    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing ZNF502
    DNA2.0 Custom Variant and Variant Library Synthesis for ZNF502

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
      --

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for ZNF502 gene integrated from 9 sources:
    (articles sorted by number of sources associating them with ZNF502)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    2. Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)
    3. An atlas of combinatorial transcriptional regulation in mouse and man. (PubMed id 20211142)1 Ravasi T....Hayashizaki Y. (2010)
    4. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)
    5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1 Ota T.... Sugano S. (2004)
    6. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 91392 HGNC: 23718 AceView: ZNF502 Ensembl:ENSG00000196653 euGenes: HUgn91392
    ECgene: ZNF502 H-InvDB: ZNF502

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for ZNF502 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for ZNF502 gene:
    Search GeneIP for patents involving ZNF502

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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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    (GIFtS: 73)
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