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Aliases for ZNF501 Gene

Aliases for ZNF501 Gene

  • Zinc Finger Protein 501 2 3 5
  • Zinc Finger Protein 52 2 3 4
  • ZNF52 3 4
  • ZNF 3

External Ids for ZNF501 Gene

Previous HGNC Symbols for ZNF501 Gene

  • ZNF52

Previous GeneCards Identifiers for ZNF501 Gene

  • GC03P044731
  • GC03P044746
  • GC03P044771
  • GC03P044794
  • GC03P044834
  • GC03P044842
  • GC03P044913

Summaries for ZNF501 Gene

GeneCards Summary for ZNF501 Gene

ZNF501 (Zinc Finger Protein 501) is a Protein Coding gene. GO annotations related to this gene include transcription factor activity, sequence-specific DNA binding. An important paralog of this gene is ZNF502.

UniProtKB/Swiss-Prot for ZNF501 Gene

  • May be involved in transcriptional regulation.

No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF501 Gene

Genomics for ZNF501 Gene

Regulatory Elements for ZNF501 Gene

Enhancers for ZNF501 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH03G045638 2.1 FANTOM5 Ensembl ENCODE dbSUPER 12.1 +914.0 914015 9.6 CREB3L1 DMAP1 FEZF1 YY1 SLC30A9 ZNF143 SP3 NFYC TBX21 MEF2D LIMD1 SACM1L XCR1 RPS24P8 ZNF501 RN7SL145P LARS2-AS1 LIMD1-AS1 EXOSC7 ZDHHC3
GH03G045130 2 FANTOM5 Ensembl ENCODE dbSUPER 9.9 +406.4 406396 11.1 HDGF PKNOX1 CREB3L1 ARNT SIN3A FEZF1 ZNF766 CBX5 FOS KLF13 RNU5B-3P CLEC3B TMEM158 ZNF501 ENSG00000202268 XCR1 CDCP1 LOC105377059
GH03G044648 1 ENCODE 12.2 -80.8 -80752 1.5 PKNOX1 CREB3L1 ARNT AGO1 SIN3A YY1 ETS1 CBX5 ELK1 ZNF143 RPS24P8 ZNF501 KIAA1143 ZNF35 ENSG00000272077
GH03G044532 1 ENCODE 10 -196.6 -196593 0.2 MLX CREB3L1 ARNT ZFP64 ARID4B SIN3A DMAP1 ZNF2 SLC30A9 ZNF766 ZNF197 ZNF852 ZKSCAN7 ENSG00000235845 TGM4 ZNF445 ZNF660 ZNF501 CLEC3B RNU5B-3P
GH03G044584 0.9 ENCODE 10.6 -144.6 -144609 1.7 FOXA2 ARID4B SIN3A ETS1 ZNF143 ZNF207 CREM THAP11 SMAD5 NFYC ZNF197 ZNF197-AS1 ZKSCAN7 ZNF501 ZNF35 PIR39553
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around ZNF501 on UCSC Golden Path with GeneCards custom track

Promoters for ZNF501 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000151598 105 1399 MLX CREB3L1 ARNT ZFP64 ARID4B DMAP1 ZBTB7B YY1 ZNF143 KLF13

Genomic Location for ZNF501 Gene

44,729,596 bp from pter
44,737,083 bp from pter
7,488 bases
Plus strand

Genomic View for ZNF501 Gene

Genes around ZNF501 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF501 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF501 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF501 Gene

Proteins for ZNF501 Gene

  • Protein details for ZNF501 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Zinc finger protein 501
    Protein Accession:
    Secondary Accessions:
    • B4DLY7
    • Q96NU9

    Protein attributes for ZNF501 Gene

    271 amino acids
    Molecular mass:
    31179 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ZNF501 Gene


neXtProt entry for ZNF501 Gene

Post-translational modifications for ZNF501 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF501 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ZNF501 Gene

Domains & Families for ZNF501 Gene

Gene Families for ZNF501 Gene

Protein Domains for ZNF501 Gene


Suggested Antigen Peptide Sequences for ZNF501 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
genes like me logo Genes that share domains with ZNF501: view

Function for ZNF501 Gene

Molecular function for ZNF501 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Gene Ontology (GO) - Molecular Function for ZNF501 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
GO:0003700 transcription factor activity, sequence-specific DNA binding IBA --
GO:0005515 protein binding IPI 25556234
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF501: view
genes like me logo Genes that share phenotypes with ZNF501: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

Clone Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for ZNF501 Gene

Localization for ZNF501 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF501 Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZNF501 gene
Compartment Confidence
nucleus 5
cytosol 2

Gene Ontology (GO) - Cellular Components for ZNF501 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF501: view

Pathways & Interactions for ZNF501 Gene

SuperPathways for ZNF501 Gene

No Data Available

Gene Ontology (GO) - Biological Process for ZNF501 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IBA,IEA --
genes like me logo Genes that share ontologies with ZNF501: view

No data available for Pathways by source and SIGNOR curated interactions for ZNF501 Gene

Drugs & Compounds for ZNF501 Gene

No Compound Related Data Available

Transcripts for ZNF501 Gene

Unigene Clusters for ZNF501 Gene

Zinc finger protein 501:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF501 Gene

ExUns: 1a · 1b · 1c · 1d ^ 2a · 2b ^ 3a · 3b
SP1: - -
SP2: -
SP3: -

Relevant External Links for ZNF501 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ZNF501 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ZNF501 Gene

Protein differential expression in normal tissues from HIPED for ZNF501 Gene

This gene is overexpressed in Platelet (28.3), CD8 Tcells (25.1), and Testis (15.6).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for ZNF501 Gene

Protein tissue co-expression partners for ZNF501 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of ZNF501 Gene:


SOURCE GeneReport for Unigene cluster for ZNF501 Gene:


Evidence on tissue expression from TISSUES for ZNF501 Gene

  • Nervous system(4.3)
  • Adrenal gland(4.1)
genes like me logo Genes that share expression patterns with ZNF501: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZNF501 Gene

Orthologs for ZNF501 Gene

This gene was present in the common ancestor of animals.

Orthologs for ZNF501 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia ZNF501 34 35
  • 99.75 (n)
(Canis familiaris)
Mammalia ZNF501 35
  • 92 (a)
(Danio rerio)
Actinopterygii si:dkey-191j3.3 35
  • 44 (a)
zgc:173575 35
  • 41 (a)
si:ch73-92e7.6 35
  • 33 (a)
si:dkey-20i20.10 35
  • 33 (a)
si:dkey-20i20.8 35
  • 33 (a)
si:dkey-20i20.3 35
  • 32 (a)
si:dkey-20i20.7 35
  • 29 (a)
si:dkey-20i20.9 35
  • 29 (a)
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP006701 34
  • 54.52 (n)
Species where no ortholog for ZNF501 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ZNF501 Gene

Gene Tree for ZNF501 (if available)
Gene Tree for ZNF501 (if available)

Paralogs for ZNF501 Gene

(573) SIMAP similar genes for ZNF501 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with ZNF501: view

Variants for ZNF501 Gene

Sequence variations from dbSNP and Humsavar for ZNF501 Gene

SNP ID Clin Chr 03 pos Sequence Context AA Info Type
rs1000138254 -- 44,730,570(+) AGTGT(C/T)AGTTA intron-variant, upstream-variant-2KB
rs1001049637 -- 44,731,680(+) GAAAA(G/T)GCAGG intron-variant
rs1001092306 -- 44,731,641(+) GGTGG(G/T)ACCCA intron-variant
rs1001544819 -- 44,732,051(+) ACATG(A/G)AGCCT intron-variant
rs1001656802 -- 44,729,854(+) AAGAA(A/G)GGAGA intron-variant, upstream-variant-2KB, utr-variant-5-prime

Variation tolerance for ZNF501 Gene

Residual Variation Intolerance Score: 90.5% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.82; 47.71% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ZNF501 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for ZNF501 Gene

Disorders for ZNF501 Gene

Relevant External Links for ZNF501

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for ZNF501 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF501 Gene

Publications for ZNF501 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 64
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 64
  3. Clustering of C2-H2 zinc finger motif sequences within telomeric and fragile site regions of human chromosomes. (PMID: 1505991) Lichter P. … Ward D.C. (Genomics 1992) 2 3 64
  4. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3 64
  5. New host factors important for respiratory syncytial virus (RSV) replication revealed by a novel microfluidics screen for interactors of matrix (M) protein. (PMID: 25556234) Kipper S. … Bajorek M. (Mol. Cell Proteomics 2015) 3 64

Products for ZNF501 Gene

Sources for ZNF501 Gene

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