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ZNF496 Gene

protein-coding   GIFtS: 51
GCID: GC01M247460

Zinc Finger Protein 496

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Aliases
for ZNF496 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Zinc Finger Protein 4961 2     ZFP4962 5
Zinc Finger Protein With KRAB And SCAN Domains 172 3     ZSCAN492
ZKSCAN172 3     NSD1 (Nuclear Receptor Binding SET-Domain Containing 1)-Interacting Zinc
Finger Protein 12
NIZP12 5     

External Ids:    HGNC: 237131   Entrez Gene: 848382   Ensembl: ENSG000001627147   OMIM: 6139115   UniProtKB: Q96IT13   

Export aliases for ZNF496 gene to outside databases

Previous GC identifers: GC01M244408 GC01M243787 GC01M245527 GC01M217858


Summaries
for ZNF496 gene

(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for ZNF496 Gene:
ZNF496 (zinc finger protein 496) is a protein-coding gene. GO annotations related to this gene include protein self-association and sequence-specific DNA binding RNA polymerase II transcription factor activity. An important paralog of this gene is ZNF263.

UniProtKB/Swiss-Prot: ZN496_HUMAN, Q96IT1
Function: DNA-binding transcription factor that can both act as an activator and a repressor (By similarity)




Genomic Views
for ZNF496 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000001.10  NT_167186.2  NC_018912.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the ZNF496 gene promoter:
         Sp1   p300   MyoD   AP-2gamma   GATA-2   Ik-2   NRF-2   AP-2beta   AP-2alpha   AP-2alphaA   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: ZNF496 promoter sequence
   Search Chromatin IP Primers for ZNF496

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat ZNF496


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1q44   Ensembl cytogenetic band:  1q44   HGNC cytogenetic band: 1q44

ZNF496 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ZNF496 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01M247460:  view genomic region     (about GC identifiers)

Start:
 247,460,714 bp from pter      End:
 247,495,148 bp from pter
Size:
 34,435 bases      Orientation:
 minus strand

Proteins
for ZNF496 gene

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: ZN496_HUMAN, Q96IT1 (See protein sequence)
Recommended Name: Zinc finger protein 496  
Size: 587 amino acids; 66908 Da
Subunit: Interacts (via zinc-fingers) with JARID2. Interacts with NSD1 (By similarity)
Secondary accessions: Q8TBS2
Alternative splicing: 2 isoforms:  Q96IT1-1   Q96IT1-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for ZNF496: NX_Q96IT1

Explore proteomics data for ZNF496 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

    • See ZNF496 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_116141.1  
    ENSEMBL proteins: 
     ENSP00000294753   ENSP00000473324   ENSP00000355454  
    Reactome Protein details: Q96IT1

    ZNF496 Human Recombinant Protein Products:

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    Novus Biologicals ZNF496 Proteins
    Novus Biologicals ZNF496 Lysates
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    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for ZNF496

         		 Search eBioscience for Proteins for ZNF496 

         		antibodies-online proteins for ZNF496 (4 products) 

         		antibodies-online peptides for ZNF496

    ZNF496 Antibody Products:

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    antibodies-online antibodies for ZNF496 (26 products) 

    ZNF496 Assay Products:

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    antibodies-online kits for ZNF496 (4 products) 

    Domains /
    Families
    for ZNF496 gene

    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    TryGeneCards Plus    		 HGNC Gene Families:
    ZNF: Zinc fingers, C2H2-type

    Selected InterPro protein domains (see all 8):
     IPR027767 Zfp496
     IPR001909 Krueppel-associated_box
     IPR008916 Retrov_capsid_C
     IPR003309 Tscrpt_reg_SCAN
     IPR015880 Znf_C2H2-like

    Graphical View of Domain Structure for InterPro Entry Q96IT1

    ProtoNet protein and cluster: Q96IT1

    2 Blocks protein domains:
    IPB001909 KRAB box
    IPB003309 Transcriptional regulator SCAN


    UniProtKB/Swiss-Prot: ZN496_HUMAN, Q96IT1
    Domain: The C2H2-type zinc finger 1, also named C2HR, mediates the interaction with NSD1 (By similarity)
    Similarity: Belongs to the krueppel C2H2-type zinc-finger protein family
    Similarity: Contains 5 C2H2-type zinc fingers
    Similarity: Contains 1 KRAB domain
    Similarity: Contains 1 SCAN box domain


    Find genes that share domains with ZNF496           About GenesLikeMe


    Function
    for ZNF496 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: ZN496_HUMAN, Q96IT1
    Function: DNA-binding transcription factor that can both act as an activator and a repressor (By similarity)

         Gene Ontology (GO): Selected molecular function terms (see all 7):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000981sequence-specific DNA binding RNA polymerase II transcription factor activity IBA--
    GO:0003676nucleic acid binding ----
    GO:0003677DNA binding ISS--
    GO:0003700sequence-specific DNA binding transcription factor activity ----
    GO:0005515protein binding IPI16189514
         
    Find genes that share ontologies with ZNF496           About GenesLikeMe


    Phenotypes:
         1 MGI phenotypic allele for Zkscan17 (no phenotypes)

    Find genes that share phenotypes with ZNF496           About GenesLikeMe

    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for ZNF496

    miRNA
    Products:            		miRTarBase miRNAs that target ZNF496:
    hsa-mir-320a (MIRT044474)

    Block miRNA regulation of human, mouse, rat ZNF496 using miScript Target Protectors
    1 qRT-PCR Assays for microRNA that regulate ZNF496:
    hsa-miR-4324
    SwitchGear 3'UTR luciferase reporter plasmid: ZNF496 3' UTR sequence
    Inhib. RNA
    Products:            		OriGene RNAi products in human, mouse, rat for ZNF496
    Predesigned siRNA for gene silencing in human, mouse, rat ZNF496

    Gene Editing
    Products:    		DNA2.0 Custom Protein Engineering Service for ZNF496

    Clone
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    OriGene ORF clones in mouse, rat for ZNF496
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    GenScript: all cDNA clones in your preferred vector: ZNF496 (NM_032752)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ZNF496
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF496

    Cell Line
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    Browse ESI BIO Cell Lines and PureStem Progenitors for ZNF496 
    In Situ Assay
    Products:       
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF496


    Localization
    for ZNF496 gene

    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    ZN496_HUMAN, Q96IT1: Nucleus (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus4

    Gene Ontology (GO): 3 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005622intracellular ----
    GO:0005634nucleus ISS--
    GO:0016604nuclear body IEA--

    Find genes that share ontologies with ZNF496           About GenesLikeMe


    Pathways & Interactions
    for ZNF496 gene

    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for ZNF496 About    
    See pathways by source

    		      Powered
    by    		     
    SuperPathContained pathways About
    1Gene Expression
    		Generic Transcription Pathway0.40
    		Gene Expression0.40


    Find genes that share SuperPaths with ZNF496           About GenesLikeMe

    Pathways by source                                   See SuperPaths
    Show all pathways


    1 Reactome Pathway for ZNF496
        Generic Transcription Pathway


        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for ZNF496
    Interactions:

        GeneGlobe Interaction Network for ZNF496

    STRING Interaction Network Preview (showing 5 interactants - click image to see 18)

    Selected Interacting proteins for ZNF496 (Q96IT11, 2, 3 ENSP000002947534) via UniProtKB, MINT, STRING, and/or I2D (see all 23)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ARR3P365751, 2, 3, ENSP000003115384EBI-743906,EBI-718116 MINT-67526 I2D: score=6 STRING: ENSP00000311538
    ZNF446Q9NWS93, ENSP000003365654I2D: score=3 STRING: ENSP00000336565
    CBX3Q131853, ENSP000003366874I2D: score=1 STRING: ENSP00000336687
    JARID2Q928333, ENSP000003412804I2D: score=1 STRING: ENSP00000341280
    NR3C1P041503, ENSP000002315094I2D: score=1 STRING: ENSP00000231509
    About this table

    Gene Ontology (GO): 4 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000122negative regulation of transcription from RNA polymerase II promoter IEA--
    GO:0006355regulation of transcription, DNA-templated ----
    GO:0006366transcription from RNA polymerase II promoter IBA--
    GO:0045893positive regulation of transcription, DNA-templated ISS--

    Find genes that share ontologies with ZNF496           About GenesLikeMe



    Drugs & Compounds
    for ZNF496 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
    About This Section

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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for ZNF496 (ZN496)



    Transcripts
    for ZNF496 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for ZNF496 gene: 
    NM_032752.1  

    Unigene Cluster for ZNF496:

    Zinc finger protein 496
    Hs.654803  [show with all ESTs]
    Unigene Representative Sequence: BX647480
    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000462139 ENST00000294753(uc001ico.3) ENST00000461277 ENST00000478225
    ENST00000477903 ENST00000366498(uc001icq.1 uc009xgv.3 uc010pyv.1)

    miRNA
    Products:             		 Block miRNA regulation of human, mouse, rat ZNF496 using miScript Target Protectors
    1 qRT-PCR Assays for microRNA that regulate ZNF496:
    hsa-miR-4324
    SwitchGear 3'UTR luciferase reporter plasmid: ZNF496 3' UTR sequence
    Inhib. RNA
    Products:             		OriGene RNAi products in human, mouse, rat for ZNF496
    Predesigned siRNA for gene silencing in human, mouse, rat ZNF496
    Clone
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    OriGene ORF clones in mouse, rat for ZNF496
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: ZNF496 (NM_032752)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ZNF496
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ZNF496
    Primer
    Products:            		OriGene qPCR primer pairs and template standards for ZNF496
    OriGene qSTAR qPCR primer pairs in human, mouse for ZNF496
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat ZNF496
      QuantiTect SYBR Green Assays in human, mouse, rat ZNF496
      QuantiFast Probe-based Assays in human, mouse, rat ZNF496

    Additional mRNA sequence: 

    AK024643.1 AK097397.1 AK098030.1 AK303258.1 AK310669.1 AK311639.1 AL133592.1 BC007263.1 
    BC025794.1 BX647480.1 

    10 DOTS entries:

    DT.211427  DT.110353  DT.100779158  DT.100779155  DT.92419783  DT.40261834  DT.100743891  DT.100769825 
    DT.121443942  DT.91843192 

    Selected AceView cDNA sequences (see all 180):

    BX392012 BU183723 AI630852 BC025794 BU739127 BQ059821 AI560693 BI256755 
    AA059423 AI570527 BU552982 BF475676 NM_032752 BU615766 Z44743 BG256610 
    BE297289 Z40566 AK024643 BG111101 CR610381 AI680700 BM466678 AA912492 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for ZNF496 (see all 11)    About this scheme

    ExUns: 1a · 1b ^ 2a · 2b · 2c ^ 3 ^ 4a · 4b ^ 5 ^ 6 ^ 7a · 7b · 7c · 7d ^ 8 ^ 9a · 9b · 9c ^ 10a · 10b ^ 11a · 11b · 11c ^ 12a · 12b · 12c ^
    SP1:                                                              -     -     -           -                       -     -           -     -     -               
    SP2:                                                              -     -     -                                   -     -           -     -     -               
    SP3:                                      -                       -     -     -           -                                                                     
    SP4:                                                                                      -                       -     -                       -     -         
    SP5:                                                                                      -                       -     -           -     -     -               

    ExUns: 13 ^ 14 ^ 15a · 15b · 15c
    SP1:  -     -                     
    SP2:  -     -                     
    SP3:                              
    SP4:                              
    SP5:                              


    ECgene alternative splicing isoforms for ZNF496

    Expression
    for ZNF496 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

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    ZNF496 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    ZNF496 Expression
    About this image

    ZNF496 Protein expression data from MOPED1, PaxDb2 and MaxQB3:     About this image

    ZNF496 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.654803
        Custom PCR Arrays for ZNF496
    Primer
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    In Situ
    Assay Products:     
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF496

    Orthologs
    for ZNF496 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

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    This gene was present in the common ancestor of human and mouse.

    Orthologs for ZNF496 gene from Selected species (see all 6)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    mouse
    (Mus musculus)    		 Mammalia Zkscan171 , 5 zinc finger with KRAB and SCAN domains 171, 5 81.18(n)1
    79(a)1    		   11 (37.72 cM)5
    2684171  NM_172941.31  NP_766529.31 
     594855205 


    ENSEMBL Gene Tree for ZNF496 (if available)
    TreeFam Gene Tree for ZNF496 (if available)

    Paralogs
    for ZNF496 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for ZNF496 gene
    ZNF2632  ZNF2022  ZSCAN252  ZNF6412  
    1 SIMAP similar gene for ZNF496 using alignment to 1 protein entry:     ZN496_HUMAN:
    ZNF501

    Find genes that share paralogs with ZNF496           About GenesLikeMe



    Genomic Variants
    for ZNF496 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
    About This Section

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    Selected SNPs for ZNF496 (see all 763)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 1 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs1412385051,2
    		--247463230(+) CTGCGA/GGGTGC 1 -- int10--------
    rs1449500341,2
    		C--247463306(+) CCCTGA/CTCCCC 1 -- int10--------
    rs1390208401,2
    		--247463555(+) CAGAAC/TACCTG 1 -- int10--------
    rs1850445711,2
    		--247463667(+) CTCCCA/CTGGCA 1 -- ut310--------
    rs1889820251,2
    		--247463724(+) GCTCTC/TTATCC 1 -- ut310--------
    rs1405789351,2
    		C--247463792(+) CCAGCA/CAGGGT 1 -- ut310--------
    rs2007308801,2
    		C--247463816(+) GCGGAA/GAGGCT 1 -- ut310--------
    rs1144992031,2
    		C,F--247463835(+) GTTCAG/AAGCCT 2 /L syn12Minor allele frequency- A:0.00WA NA 4648
    rs1409618221,2
    		F--247463884(+) AGGAGG/ATCATA 2 /D syn11Minor allele frequency- A:0.00NA 4548
    rs1819013161,2
    		C--247464002(+) CCTTCC/TCACAC 2 E G mis10--------

    HapMap Linkage Disequilibrium report for ZNF496 (247460714 - 247495148 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 10 variations for ZNF496:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv992675CNV Deletion20482838
    dgv73e201CNV Deletion23290073
    esv4468CNV Deletion18987735
    esv2335854CNV Deletion18987734
    nsv509790CNV Insertion20534489
    nsv833126CNV Loss17160897
    esv21506CNV Loss19812545
    nsv873439CNV Loss21882294
    nsv833137CNV Gain17160897
    esv33129CNV Gain+Loss17666407

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    Disorders / Diseases
    for ZNF496 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    TryGeneCards Plus    		 OMIM gene information: 613911    OMIM disorders: --

    1 inferred disease relationship from the University of Copenhagen DISEASES database for ZNF496:
    Sotos syndrome

    Find genes that share disorders with ZNF496           About GenesLikeMe

    Genetic Association Database (GAD): ZNF496

    Export disorders for ZNF496 gene to outside databases

    Publications
    for ZNF496 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

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    PubMed articles for ZNF496 gene, integrated from 10 sources (see all 15):
    (articles sorted by number of sources associating them with ZNF496)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
    3. Systematic and quantitative assessment of the ubiquitin-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (Mol. Cell 2011)
    4. NSD1 PHD domains bind methylated H3K4 and H3K9 using interactions disrupted by point mutations in human sotos syndrome. (PubMed id 21972110)1 Pasillas M.P....Kamps M.P. (Hum. Mutat. 2011)
    5. Global identification of modular cullin-RING ligase substrates. (PubMed id 21963094)1 Emanuele M.J....Elledge S.J. (Cell 2011)
    6. The NIZP1 KRAB and C2HR domains cross-talk for transcriptional regulation. (PubMed id 20176155)1 Losson R. and Nielsen A.L. (Biochim. Biophys. Acta 2010)
    7. An atlas of combinatorial transcriptional regulation in mouse and man. (PubMed id 20211142)1 Ravasi T....Hayashizaki Y. (Cell 2010)
    8. Direct binding of CoREST1 to SUMO-2/3 contributes to gene-specific repression by the LSD1/CoREST1/HDAC complex. (PubMed id 19394292)1 Ouyang J....Gill G. (Mol. Cell 2009)
    9. Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions. (PubMed id 19690332)2 Mayya V.... Han D.K. (Sci. Signal. 2009)
    10. Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis. (PubMed id 18220336)2 Cantin G.T....Yates J.R. III (J. Proteome Res. 2008)

    External Searches for ZNF496 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
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    Genome Databases showing ZNF496 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

    TryGeneCards Plus
    Entrez Gene: 84838 HGNC: 23713 AceView: ZNF496 Ensembl:ENSG00000162714 euGenes: HUgn84838
    ECgene: ZNF496 H-InvDB: ZNF496

    Other Databases showing ZNF496 gene

    (According to HUGE)
    About This Section

    TryGeneCards Plus    		   --

    Specialized Databases showing ZNF496 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    PharmGKB entry for ZNF496 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for ZNF496 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

    TryGeneCards Plus    		Patent Information for ZNF496 gene:
    Search GeneIP for patents involving ZNF496

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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