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ZNF496 Gene

protein-coding GIFtS: 51
GCID: GC01M247460

Zinc Finger Protein 496

Microbiology & Infectious Diseases Congress

See related disease
at

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(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, ¹⁰fRNAdb, ¹²H-InvDB, ¹³NCBI, ¹⁴NONCODE, and/or ¹⁵RNAdb)
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Aliases
Zinc Finger Protein 496¹ ²		ZFP496² ⁵
Zinc Finger Protein With KRAB And SCAN Domains 17² ³		ZSCAN49²
ZKSCAN17² ³		NSD1 (Nuclear Receptor Binding SET-Domain Containing 1)-Interacting Zinc Finger Protein 1²
NIZP1² ⁵

External Ids:	HGNC: 23713¹	Entrez Gene: 84838²	Ensembl: ENSG00000162714⁷	OMIM: 613911⁵	UniProtKB: Q96IT1³

Export aliases for ZNF496 gene to outside databases

Previous GC identifers: GC01M244408 GC01M243787 GC01M245527 GC01M217858

(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for ZNF496 Gene:

ZNF496 (zinc finger protein 496) is a protein-coding gene. Diseases associated with ZNF496 include sotos syndrome. GO annotations related to this gene include protein self-association and sequence-specific DNA binding RNA polymerase II transcription factor activity. An important paralog of this gene is ZNF263.

UniProtKB/Swiss-Prot: ZN496_HUMAN, Q96IT1

Function: DNA-binding transcription factor that can both act as an activator and a repressor (By similarity)

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:

NC_000001.11 NT_167186.2 NC_018912.2

Regulatory elements:

Regulatory transcription factor binding sites in the ZNF496 gene promoter:
Sp1 p300 MyoD AP-2gamma GATA-2 Ik-2 NRF-2 AP-2beta AP-2alpha AP-2alphaA
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: ZNF496 promoter sequence

Search Chromatin IP Primers for ZNF496

Epigenetics:

DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat ZNF496

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1q44 Ensembl cytogenetic band: 1q44 HGNC cytogenetic band: 1q44

ZNF496 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ZNF496 gene location

GeneLoc information about chromosome 1 GeneLoc Exon Structure

GeneLoc location for GC01M247460: view genomic region (about GC identifiers)

Start:	247,460,714 bp from pter	End:	247,495,148 bp from pter
Size:	34,435 bases	Orientation:	minus strand

(According to ¹UniProtKB, HORDE, ²neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: ZN496_HUMAN, Q96IT1 (See protein sequence)

Recommended Name: Zinc finger protein 496

Size: 587 amino acids; 66908 Da

Subunit: Interacts (via zinc-fingers) with JARID2. Interacts with NSD1 (By similarity)

Secondary accessions: Q8TBS2

Alternative splicing: 2 isoforms: Q96IT1-1 Q96IT1-2 (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for ZNF496: NX_Q96IT1

Explore proteomics data for ZNF496 at MOPED

Post-translational modifications:

Modification sites at neXtProt

Modification sites at PhosphoSitePlus

See ZNF496 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

REFSEQ proteins: NP_116141.1

ENSEMBL proteins:

ENSP00000294753 ENSP00000473324 ENSP00000355454

Reactome Protein details: Q96IT1

ZNF496 Human Recombinant Protein Products:

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(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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HGNC Gene Families:

ZNF: Zinc fingers, C2H2-type

Selected InterPro protein domains (see all 8):

IPR027767 Zfp496

IPR001909 Krueppel-associated_box

IPR008916 Retrov_capsid_C

IPR003309 Tscrpt_reg_SCAN

IPR015880 Znf_C2H2-like

Graphical View of Domain Structure for InterPro Entry Q96IT1

ProtoNet protein and cluster: Q96IT1

2 Blocks protein domains:

IPB001909 KRAB box

IPB003309 Transcriptional regulator SCAN

UniProtKB/Swiss-Prot: ZN496_HUMAN, Q96IT1

Domain: The C2H2-type zinc finger 1, also named C2HR, mediates the interaction with NSD1 (By similarity)

Similarity: Belongs to the krueppel C2H2-type zinc-finger protein family

Similarity: Contains 5 C2H2-type zinc fingers

Similarity: Contains 1 KRAB domain

Similarity: Contains 1 SCAN box domain

ZNF496 for domains About GeneDecksing

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Molecular Function:

UniProtKB/Swiss-Prot Summary: ZN496_HUMAN, Q96IT1

Function: DNA-binding transcription factor that can both act as an activator and a repressor (By similarity)

Gene Ontology (GO): Selected molecular function terms (see all 7): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0000981	sequence-specific DNA binding RNA polymerase II transcription factor activity	IBA	--
GO:0003676	nucleic acid binding	--	--
GO:0003677	DNA binding	ISS	--
GO:0003700	sequence-specific DNA binding transcription factor activity	--	--
GO:0005515	protein binding	IPI	16189514

ZNF496 for ontologies About GeneDecksing

Phenotypes:
1 MGI phenotypic allele

for Zkscan17 (no phenotypes)

ZNF496 for phenotypes About GeneDecksing

Animal Models:

inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for ZNF496

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genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for ZNF496

genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for ZNF496

miRNA Products:		miRTarBase miRNAs that target ZNF496: hsa-mir-320a (MIRT044474)

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		1 qRT-PCR Assays for microRNA that regulate ZNF496:
		hsa-miR-4324
		SwitchGear 3'UTR luciferase reporter plasmid: ZNF496 3' UTR sequence

Inhib. RNA Products:		OriGene RNAi products in human, mouse, rat for ZNF496
		Predesigned siRNA for gene silencing in human, mouse, rat ZNF496

Gene Editing
Products:

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In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF496

(According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Subcellular locations from UniProtKB/Swiss-Prot

ZN496_HUMAN, Q96IT1: Nucleus (By similarity)

Subcellular locations from COMPARTMENTS:

Compartment	Confidence
nucleus	4

About this image

Gene Ontology (GO): 3 cellular component terms: About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005622	intracellular	--	--
GO:0005634	nucleus	ISS	--
GO:0016604	nuclear body	IEA	--

ZNF496 for ontologies About GeneDecksing

(SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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SuperPaths for ZNF496 About

See pathways by source

SuperPath

Contained pathways About

Gene Expression

Generic Transcription Pathway

0.40

Gene Expression

0.40

Pathways by source See SuperPaths
Show all pathways

1 Reactome Pathway for ZNF496

Generic Transcription Pathway

ZNF496 for pathways About GeneDecksing

Custom Pathway & Disease-focused RT² Profiler PCR Arrays for ZNF496
Interactions:

GeneGlobe Interaction Network for ZNF496

STRING Interaction Network Preview (showing 5 interactants - click image to see 18)

Selected Interacting proteins for ZNF496 (Q96IT1^{1, 2, 3} ENSP00000294753⁴) via UniProtKB, MINT, STRING, and/or I2D (see all 23)

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
ARR3	P36575¹^,²^,³, ENSP00000311538⁴	EBI-743906,EBI-718116 MINT-67526 I2D: score=6 STRING: ENSP00000311538
ZNF446	Q9NWS9³, ENSP00000336565⁴	I2D: score=3 STRING: ENSP00000336565
CBX3	Q13185³, ENSP00000336687⁴	I2D: score=1 STRING: ENSP00000336687
JARID2	Q92833³, ENSP00000341280⁴	I2D: score=1 STRING: ENSP00000341280
NR3C1	P04150³, ENSP00000231509⁴	I2D: score=1 STRING: ENSP00000231509

About this table

Gene Ontology (GO): 4 biological process terms: About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	IEA	--
GO:0006355	regulation of transcription, DNA-templated	--	--
GO:0006366	transcription from RNA polymerase II promoter	IBA	--
GO:0045893	positive regulation of transcription, DNA-templated	ISS	--

ZNF496 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse compounds at ApexBio

Browse Tocris compounds for ZNF496 (ZN496)

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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REFSEQ mRNAs for ZNF496 gene:

NM_032752.1

Unigene Cluster for ZNF496:

Zinc finger protein 496

Hs.654803 [show with all ESTs]

Unigene Representative Sequence: BX647480

6 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000462139 ENST00000294753(uc001ico.3) ENST00000461277 ENST00000478225

ENST00000477903 ENST00000366498(uc001icq.1 uc009xgv.3 uc010pyv.1)

Congresses - knowledge worth sharing:
European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) 10 - 13 May 2014

miRNA Products:		Block miRNA regulation of human, mouse, rat ZNF496 using miScript Target Protectors
		1 qRT-PCR Assays for microRNA that regulate ZNF496:
		hsa-miR-4324
		SwitchGear 3'UTR luciferase reporter plasmid: ZNF496 3' UTR sequence

Inhib. RNA Products:		OriGene RNAi products in human, mouse, rat for ZNF496
		Predesigned siRNA for gene silencing in human, mouse, rat ZNF496

Clone Products:		OriGene clones in human, mouse for ZNF496 (see all 6) OriGene ORF clones in mouse, rat for ZNF496 OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
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		Pre-validated RT² qPCR Primer Assay in human, mouse, rat ZNF496
		QuantiTect SYBR Green Assays in human, mouse, rat ZNF496
		QuantiFast Probe-based Assays in human, mouse, rat ZNF496

Additional mRNA sequence:

AK024643.1 AK097397.1 AK098030.1 AK303258.1 AK310669.1 AK311639.1 AL133592.1 BC007263.1

BC025794.1 BX647480.1

10 DOTS entries:

DT.211427 DT.110353 DT.100779158 DT.100779155 DT.92419783 DT.40261834 DT.100743891 DT.100769825

DT.121443942 DT.91843192

Selected AceView cDNA sequences (see all 180):

BX392012 BU183723 AI630852 BC025794 BU739127 BQ059821 AI560693 BI256755

AA059423 AI570527 BU552982 BF475676 NM_032752 BU615766 Z44743 BG256610

BE297289 Z40566 AK024643 BG111101 CR610381 AI680700 BM466678 AA912492

GeneLoc Exon Structure

Selected Alternative Splicing Database (ASD) splice patterns (SP) for ZNF496 (see all 11) About this scheme

ExUns:	1a	·	1b	^	2a	·	2b	·	2c	^	3	^	4a	·	4b	^	5	^	6	^	7a	·	7b	·	7c	·	7d	^	8	^	9a	·	9b	·	9c	^	10a	·	10b	^	11a	·	11b	·	11c	^	12a	·	12b	·	12c	^
SP1:																					-		-		-				-								-		-				-		-		-
SP2:																					-		-		-												-		-				-		-		-
SP3:													-								-		-		-				-
SP4:																													-								-		-								-		-
SP5:																													-								-		-				-		-		-

ExUns:	13	^	14	^	15a	·	15b	·	15c
SP1:	-		-
SP2:	-		-
SP3:
SP4:
SP5:

ECgene alternative splicing isoforms for ZNF496

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE ¹MOPED, ²PaxDb, and ³MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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ZNF496 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>^2/3
CGAP TAG: --

About this image

ZNF496 Protein expression data from MOPED¹, PaxDb² and MaxQB³:

About this image

ZNF496 Protein Expression

SOURCE GeneReport for Unigene cluster: Hs.654803

Custom PCR Arrays for ZNF496

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In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ZNF496

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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This gene was present in the common ancestor of human and mouse.

Orthologs for ZNF496 gene from Selected species (see all 6) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
mouse (Mus musculus)	Mammalia	Zkscan17^{1 , 5}	zinc finger with KRAB and SCAN domains 17^{1, 5}	81.18(n)¹ 79(a)¹		11 (37.72 cM)⁵ 268417¹ NM_172941.3¹ NP_766529.3¹ 59485520⁵

ENSEMBL Gene Tree for ZNF496 (if available)
TreeFam Gene Tree for ZNF496 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
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Paralogs for ZNF496 gene

ZNF263² ZNF202² ZSCAN25² ZNF641²

1 SIMAP similar gene for ZNF496 using alignment to 1 protein entry: ZN496_HUMAN:

ZNF501

ZNF496 for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, ⁴UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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SNP ID	Valid	Clinical significance	Chr 1 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs141238505^1,2		--	247463230(+)	`CTGCGA/GGGTGC`	1	--	int¹		0	--	--	--	--
rs144950034^1,2	C	--	247463306(+)	`CCCTGA/CTCCCC`	1	--	int¹		0	--	--	--	--
rs139020840^1,2		--	247463555(+)	`CAGAAC/TACCTG`	1	--	int¹		0	--	--	--	--
rs185044571^1,2		--	247463667(+)	`CTCCCA/CTGGCA`	1	--	ut3¹		0	--	--	--	--
rs188982025^1,2		--	247463724(+)	`GCTCTC/TTATCC`	1	--	ut3¹		0	--	--	--	--
rs140578935^1,2	C	--	247463792(+)	`CCAGCA/CAGGGT`	1	--	ut3¹		0	--	--	--	--
rs200730880^1,2	C	--	247463816(+)	`GCGGAA/GAGGCT`	1	--	ut3¹		0	--	--	--	--
rs114499203^1,2	C,F	--	247463835(+)	`GTTCAG/AAGCCT`	2	/L	syn¹		2		WA NA	4648
rs140961822^1,2	F	--	247463884(+)	`AGGAGG/ATCATA`	2	/D	syn¹		1		NA	4548
rs181901316^1,2	C	--	247464002(+)	`CCTTCC/TCACAC`	2	E G	mis¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for ZNF496 (247460714 - 247495148 bp)

Structural Variations
Database of Genomic Variants (DGV) 10 variations for ZNF496: About this table

Variant ID	Type	Subtype	PubMed ID
esv992675	CNV	Deletion	20482838
dgv73e201	CNV	Deletion	23290073
esv4468	CNV	Deletion	18987735
esv2335854	CNV	Deletion	18987734
nsv509790	CNV	Insertion	20534489
nsv833126	CNV	Loss	17160897
esv21506	CNV	Loss	19812545
nsv873439	CNV	Loss	21882294
nsv833137	CNV	Gain	17160897
esv33129	CNV	Gain+Loss	17666407

Site Specific Mutation Identification with PCR Assays

SeqTarget long-range PCR primers for resequencing ZNF496

DNA2.0 Custom Variant and Variant Library Synthesis for ZNF496

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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OMIM gene information: 613911 OMIM disorders: --

1 disease for ZNF496:
About MalaCards

sotos syndrome

1 disease from the University of Copenhagen DISEASES database for ZNF496:

Sotos syndrome

ZNF496 for disorders About GeneDecksing

Genetic Association Database (GAD): ZNF496

Export disorders for ZNF496 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
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PubMed articles for ZNF496 gene, integrated from 10 sources (see all 15):
(articles sorted by number of sources associating them with ZNF496)

Utopia: connect your pdf to the dynamic
world of online information

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S.... Malek J. (Genome Res. 2004)
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)^{1, 3} Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
Systematic and quantitative assessment of the ubiquitin-modified proteome. (PubMed id 21906983)¹ Kim W....Gygi S.P. (Mol. Cell 2011)
NSD1 PHD domains bind methylated H3K4 and H3K9 using interactions disrupted by point mutations in human sotos syndrome. (PubMed id 21972110)¹ Pasillas M.P....Kamps M.P. (Hum. Mutat. 2011)
Global identification of modular cullin-RING ligase substrates. (PubMed id 21963094)¹ Emanuele M.J....Elledge S.J. (Cell 2011)
The NIZP1 KRAB and C2HR domains cross-talk for transcriptional regulation. (PubMed id 20176155)¹ Losson R. and Nielsen A.L. (Biochim. Biophys. Acta 2010)
An atlas of combinatorial transcriptional regulation in mouse and man. (PubMed id 20211142)¹ Ravasi T....Hayashizaki Y. (Cell 2010)
Direct binding of CoREST1 to SUMO-2/3 contributes to gene-specific repression by the LSD1/CoREST1/HDAC complex. (PubMed id 19394292)¹ Ouyang J....Gill G. (Mol. Cell 2009)
Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions. (PubMed id 19690332)² Mayya V.... Han D.K. (Sci. Signal. 2009)
Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis. (PubMed id 18220336)² Cantin G.T....Yates J.R. III (J. Proteome Res. 2008)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Free Text

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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 84838	HGNC: 23713	AceView: ZNF496	Ensembl:ENSG00000162714	euGenes: HUgn84838
ECgene: ZNF496	H-InvDB: ZNF496

(According to HUGE)
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(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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Name	Description
PharmGKB entry for ZNF496	Pharmacogenomics, SNPs, Pathways

Intellectual Property for ZNF496 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

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Patent Information for ZNF496 gene:
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(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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ZNF496 Gene

Zinc Finger Protein 496

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ZNF496 Gene

Zinc Finger Protein 496

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