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Aliases for ZNF485 Gene

Aliases for ZNF485 Gene

  • Zinc Finger Protein 485 2 3 5

External Ids for ZNF485 Gene

Previous GeneCards Identifiers for ZNF485 Gene

  • GC10P043256
  • GC10P043421
  • GC10P044101
  • GC10P040628

Summaries for ZNF485 Gene

GeneCards Summary for ZNF485 Gene

ZNF485 (Zinc Finger Protein 485) is a Protein Coding gene. Among its related pathways are Gene Expression. GO annotations related to this gene include nucleic acid binding. An important paralog of this gene is ZNF34.

UniProtKB/Swiss-Prot for ZNF485 Gene

  • May be involved in transcriptional regulation.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF485 Gene

Genomics for ZNF485 Gene

Regulatory Elements for ZNF485 Gene

Enhancers for ZNF485 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around ZNF485 on UCSC Golden Path with GeneCards custom track

Promoters for ZNF485 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around ZNF485 on UCSC Golden Path with GeneCards custom track

Genomic Location for ZNF485 Gene

43,606,407 bp from pter
43,617,904 bp from pter
11,498 bases
Plus strand

Genomic View for ZNF485 Gene

Genes around ZNF485 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF485 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF485 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF485 Gene

Proteins for ZNF485 Gene

  • Protein details for ZNF485 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Zinc finger protein 485
    Protein Accession:
    Secondary Accessions:
    • B4DSE6
    • Q96CL0

    Protein attributes for ZNF485 Gene

    441 amino acids
    Molecular mass:
    50280 Da
    Quaternary structure:
    No Data Available
    • Sequence=AAH14161.1; Type=Frameshift; Positions=3; Evidence={ECO:0000305}; Sequence=CAH73487.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};

    Alternative splice isoforms for ZNF485 Gene


neXtProt entry for ZNF485 Gene

Proteomics data for ZNF485 Gene at MOPED

Post-translational modifications for ZNF485 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF485 Gene

No data available for DME Specific Peptides for ZNF485 Gene

Domains & Families for ZNF485 Gene

Gene Families for ZNF485 Gene

Protein Domains for ZNF485 Gene

Suggested Antigen Peptide Sequences for ZNF485 Gene

Graphical View of Domain Structure for InterPro Entry



  • Contains 1 KRAB domain.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 11 C2H2-type zinc fingers.
  • Contains 1 KRAB domain.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 11 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF485: view

Function for ZNF485 Gene

Molecular function for ZNF485 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.
genes like me logo Genes that share phenotypes with ZNF485: view

Animal Model Products

CRISPR Products

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF485 Gene

Localization for ZNF485 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF485 Gene

Subcellular locations from

Jensen Localization Image for ZNF485 Gene COMPARTMENTS Subcellular localization image for ZNF485 gene
Compartment Confidence
nucleus 5
cytosol 2

No data available for Gene Ontology (GO) - Cellular Components for ZNF485 Gene

Pathways & Interactions for ZNF485 Gene

SuperPathways for ZNF485 Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF485: view

Pathways by source for ZNF485 Gene

2 Reactome pathways for ZNF485 Gene

Interacting Proteins for ZNF485 Gene

Gene Ontology (GO) - Biological Process for ZNF485 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF485: view

No data available for SIGNOR curated interactions for ZNF485 Gene

Drugs & Compounds for ZNF485 Gene

No Compound Related Data Available

Transcripts for ZNF485 Gene

Unigene Clusters for ZNF485 Gene

Zinc finger protein 485:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF485 Gene

ExUns: 1a · 1b · 1c · 1d ^ 2a · 2b ^ 3 ^ 4 ^ 5a · 5b
SP1: - -
SP2: -
SP3: -

Relevant External Links for ZNF485 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ZNF485 Gene

mRNA expression in normal human tissues for ZNF485 Gene

Protein differential expression in normal tissues from HIPED for ZNF485 Gene

This gene is overexpressed in Plasma (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for ZNF485 Gene

SOURCE GeneReport for Unigene cluster for ZNF485 Gene Hs.147440

genes like me logo Genes that share expression patterns with ZNF485: view

Protein tissue co-expression partners for ZNF485 Gene

- Elite partner

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ZNF485 Gene

Orthologs for ZNF485 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF485 Gene

Organism Taxonomy Gene Similarity Type Details
(Canis familiaris)
Mammalia ZNF485 35
  • 88.31 (n)
  • 85.42 (a)
ZNF485 36
  • 84 (a)
(Pan troglodytes)
Mammalia ZNF485 35
  • 99.7 (n)
  • 99.09 (a)
ZNF485 36
  • 99 (a)
Species with no ortholog for ZNF485:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF485 Gene

Gene Tree for ZNF485 (if available)
Gene Tree for ZNF485 (if available)

Paralogs for ZNF485 Gene

(553) SIMAP similar genes for ZNF485 Gene using alignment to 3 proteins: Pseudogenes for ZNF485 Gene

genes like me logo Genes that share paralogs with ZNF485: view

Variants for ZNF485 Gene

Sequence variations from dbSNP and Humsavar for ZNF485 Gene

SNP ID Clin Chr 10 pos Sequence Context AA Info Type
rs12354886 - 43,616,797(+) CCTTC(A/G)CTCAG reference, missense
rs3123679 -- 43,614,696(-) TGTTA(A/G)TAAAT intron-variant
rs3123680 -- 43,612,681(-) GATGT(A/G)GAGAA intron-variant
rs3123681 -- 43,612,314(-) AAAAC(A/G)TAAAT intron-variant
rs3123682 -- 43,611,835(-) AATCT(A/C)ACAGT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF485 Gene

Variant ID Type Subtype PubMed ID
nsv522992 CNV Loss 19592680

Variation tolerance for ZNF485 Gene

Residual Variation Intolerance Score: 36.5% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 4.74; 66.43% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for ZNF485 Gene

Disorders for ZNF485 Gene

Relevant External Links for ZNF485

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator
Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for ZNF485 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF485 Gene

Publications for ZNF485 Gene

  1. A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease. (PMID: 16385451) Grupe A. … Goate A. (Am. J. Hum. Genet. 2006) 3 48 67
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3
  3. The DNA sequence and comparative analysis of human chromosome 10. (PMID: 15164054) Deloukas P. … Rogers J. (Nature 2004) 3
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for ZNF485 Gene

Sources for ZNF485 Gene