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Aliases for ZNF484 Gene

Aliases for ZNF484 Gene

  • Zinc Finger Protein 484 2 3 5
  • KRAB Box Containing C2H2 Type Zinc Finger BA526D8.4 3
  • BA526D8.4 3

External Ids for ZNF484 Gene

Previous GeneCards Identifiers for ZNF484 Gene

  • GC09M092687
  • GC09M094648
  • GC09M095609
  • GC09M065285

Summaries for ZNF484 Gene

GeneCards Summary for ZNF484 Gene

ZNF484 (Zinc Finger Protein 484) is a Protein Coding gene. Among its related pathways are Gene Expression. GO annotations related to this gene include nucleic acid binding and transcription factor activity, sequence-specific DNA binding. An important paralog of this gene is ZNF41.

UniProtKB/Swiss-Prot for ZNF484 Gene

  • May be involved in transcriptional regulation.

Additional gene information for ZNF484 Gene

No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF484 Gene

Genomics for ZNF484 Gene

Regulatory Elements for ZNF484 Gene

Enhancers for ZNF484 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH09H093090 1.9 FANTOM5 Ensembl ENCODE dbSUPER 11.4 -217.6 -217612 9.5 HDGF PKNOX1 ARID4B SIN3A DMAP1 ZBTB7B YY1 ZNF766 ZNF207 ZNF143 PHF2 LINC00475 NOL8 NINJ1 CARD19 IARS ZNF484 SUSD3 IPPK LOC101927993
GH09H093125 1.6 FANTOM5 ENCODE dbSUPER 13.1 -252.5 -252514 10.1 HDGF PKNOX1 FOXA2 MLX ZFP64 ARID4B SIN3A DMAP1 ZNF766 ZNF143 NINJ1 CARD19 ZNF484 LOC101927993 SUSD3 PHF2 IPPK
GH09H092323 1.4 ENCODE dbSUPER 14.8 +552.6 552627 3 MLX ZFP64 FEZF1 DMAP1 YY1 ZNF143 SP3 NFYC ZC3H11A MEF2D NOL8 CENPP MTND4P15 IARS LINC00475 ZNF484 ENSG00000236115 HSPE1P22 RPL21P82 RPL21P86
GH09H092761 1.4 ENCODE dbSUPER 11.4 +113.9 113853 4.6 HDGF PKNOX1 ARNT ARID4B SIN3A DMAP1 YY1 SLC30A9 ZNF207 ZNF143 PHF2 CENPP CARD19 ZNF484 LINC00475 IPPK ECM2 BICD2 GC09P092689
GH09H092607 1.4 Ensembl ENCODE dbSUPER 11.2 +267.9 267866 5.6 MLX ZNF195 THRB RARA ZNF350 RCOR1 ZNF174 REST ZNF398 ZNF662 LINC00475 PHF2 NOL8 CENPP IARS ZNF484 MTND4P15 IPPK CARD19 PIR58934
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around ZNF484 on UCSC Golden Path with GeneCards custom track

Promoters for ZNF484 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000237963 358 1401 HDGF PKNOX1 FOXA2 MLX ARID4B SIN3A DMAP1 YY1 SLC30A9 ZNF766

Genomic Locations for ZNF484 Gene

Genomic Locations for ZNF484 Gene
35,486 bases
Minus strand

Genomic View for ZNF484 Gene

Genes around ZNF484 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF484 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF484 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF484 Gene

Proteins for ZNF484 Gene

  • Protein details for ZNF484 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Zinc finger protein 484
    Protein Accession:
    Secondary Accessions:
    • B1AL89
    • B4DRI2

    Protein attributes for ZNF484 Gene

    852 amino acids
    Molecular mass:
    98221 Da
    Quaternary structure:
    No Data Available

    Three dimensional structures from OCA and Proteopedia for ZNF484 Gene

    Alternative splice isoforms for ZNF484 Gene


neXtProt entry for ZNF484 Gene

Post-translational modifications for ZNF484 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for ZNF484 Gene

Domains & Families for ZNF484 Gene

Gene Families for ZNF484 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins
  • Transcription factors

Protein Domains for ZNF484 Gene

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
genes like me logo Genes that share domains with ZNF484: view

Function for ZNF484 Gene

Molecular function for ZNF484 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Gene Ontology (GO) - Molecular Function for ZNF484 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
GO:0003700 transcription factor activity, sequence-specific DNA binding IBA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF484: view
genes like me logo Genes that share phenotypes with ZNF484: view

miRNA for ZNF484 Gene

miRTarBase miRNAs that target ZNF484

Clone Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF484 Gene

Localization for ZNF484 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF484 Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ZNF484 gene
Compartment Confidence
nucleus 5
cytosol 3

Subcellular locations from the

Human Protein Atlas (HPA)
  • Cytosol (2)
  • Nuclear membrane (2)
  • Nucleoplasm (2)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for ZNF484 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular IEA --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF484: view

Pathways & Interactions for ZNF484 Gene

SuperPathways for ZNF484 Gene

SuperPathway Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF484: view

Pathways by source for ZNF484 Gene

2 Reactome pathways for ZNF484 Gene

Interacting Proteins for ZNF484 Gene

Gene Ontology (GO) - Biological Process for ZNF484 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IBA --
genes like me logo Genes that share ontologies with ZNF484: view

No data available for SIGNOR curated interactions for ZNF484 Gene

Drugs & Compounds for ZNF484 Gene

No Compound Related Data Available

Transcripts for ZNF484 Gene

Unigene Clusters for ZNF484 Gene

Zinc finger protein 484:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF484 Gene

ExUns: 1a · 1b · 1c · 1d · 1e · 1f ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7a · 7b · 7c · 7d · 7e
SP1: -
SP2: - - -
SP3: - - -
SP4: - - - -
SP5: - - - - - -

Relevant External Links for ZNF484 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ZNF484 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ZNF484 Gene

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for ZNF484 Gene

NURSA nuclear receptor signaling pathways regulating expression of ZNF484 Gene:


SOURCE GeneReport for Unigene cluster for ZNF484 Gene:


Evidence on tissue expression from TISSUES for ZNF484 Gene

  • Muscle(2.1)
genes like me logo Genes that share expression patterns with ZNF484: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for ZNF484 Gene

Orthologs for ZNF484 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF484 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia ZNF484 33 34
  • 99.69 (n)
(Canis familiaris)
Mammalia ZNF484 33
  • 86.5 (n)
(Bos Taurus)
Mammalia ZNF484 33
  • 85.46 (n)
-- 34
  • 56 (a)
Species where no ortholog for ZNF484 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF484 Gene

Gene Tree for ZNF484 (if available)
Gene Tree for ZNF484 (if available)

Paralogs for ZNF484 Gene

Paralogs for ZNF484 Gene

(401) SIMAP similar genes for ZNF484 Gene using alignment to 1 proteins: Pseudogenes for ZNF484 Gene

genes like me logo Genes that share paralogs with ZNF484: view

Variants for ZNF484 Gene

Sequence variations from dbSNP and Humsavar for ZNF484 Gene

SNP ID Clin Chr 09 pos Sequence Context AA Info Type
rs1000092652 -- 92,849,799(+) CTCTC(-/TCTT)TTTTT intron-variant
rs1000152821 -- 92,843,244(+) TTAAC(A/G)CCATT intron-variant
rs1000183374 -- 92,843,026(+) AGACA(C/T)CTGAG intron-variant
rs1000347631 -- 92,877,720(+) CACCA(C/T)CAGAG intron-variant
rs1000446508 -- 92,850,095(+) CAAGC(C/T)CAGCC intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF484 Gene

Variant ID Type Subtype PubMed ID
nsv972781 CNV duplication 23825009
nsv831654 CNV gain 17160897
esv3576684 CNV gain 25503493
esv3545131 CNV deletion 23714750
esv3407276 CNV insertion 20981092
esv2738775 CNV deletion 23290073
esv2671782 CNV deletion 23128226
esv2468145 CNV deletion 19546169
esv1653300 CNV deletion 17803354

Variation tolerance for ZNF484 Gene

Residual Variation Intolerance Score: 67.4% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 4.81; 66.93% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ZNF484 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF484 Gene

Disorders for ZNF484 Gene

Relevant External Links for ZNF484

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for ZNF484 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF484 Gene

Publications for ZNF484 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 60
  2. DNA sequence and analysis of human chromosome 9. (PMID: 15164053) Humphray SJ … Dunham I (Nature 2004) 3 4 60
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 60
  4. Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation. (PMID: 28112733) Hendriks IA … Nielsen ML (Nature structural & molecular biology 2017) 4 60
  5. Genome-wide association for abdominal subcutaneous and visceral adipose reveals a novel locus for visceral fat in women. (PMID: 22589738) Fox CS … Borecki IB (PLoS genetics 2012) 3 60

Products for ZNF484 Gene

Sources for ZNF484 Gene

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