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Aliases for ZNF484 Gene

Aliases for ZNF484 Gene

  • Zinc Finger Protein 484 2 3 5
  • KRAB Box Containing C2H2 Type Zinc Finger BA526D8.4 3
  • BA526D8.4 3

External Ids for ZNF484 Gene

Previous GeneCards Identifiers for ZNF484 Gene

  • GC09M092687
  • GC09M094648
  • GC09M095609
  • GC09M065285

Summaries for ZNF484 Gene

GeneCards Summary for ZNF484 Gene

ZNF484 (Zinc Finger Protein 484) is a Protein Coding gene. Among its related pathways are Gene Expression. GO annotations related to this gene include nucleic acid binding and transcription factor activity, sequence-specific DNA binding. An important paralog of this gene is ZNF607.

UniProtKB/Swiss-Prot for ZNF484 Gene

  • May be involved in transcriptional regulation.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF484 Gene

Genomics for ZNF484 Gene

Regulatory Elements for ZNF484 Gene

Enhancers for ZNF484 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around ZNF484 on UCSC Golden Path with GeneCards custom track

Promoters for ZNF484 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around ZNF484 on UCSC Golden Path with GeneCards custom track

Genomic Location for ZNF484 Gene

Chromosome:
9
Start:
92,842,573 bp from pter
End:
92,878,058 bp from pter
Size:
35,486 bases
Orientation:
Minus strand

Genomic View for ZNF484 Gene

Genes around ZNF484 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF484 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF484 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF484 Gene

Proteins for ZNF484 Gene

  • Protein details for ZNF484 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q5JVG2-ZN484_HUMAN
    Recommended name:
    Zinc finger protein 484
    Protein Accession:
    Q5JVG2
    Secondary Accessions:
    • B1AL89
    • B4DRI2

    Protein attributes for ZNF484 Gene

    Size:
    852 amino acids
    Molecular mass:
    98221 Da
    Quaternary structure:
    No Data Available

    Three dimensional structures from OCA and Proteopedia for ZNF484 Gene

    Alternative splice isoforms for ZNF484 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZNF484 Gene

Proteomics data for ZNF484 Gene at MOPED

Post-translational modifications for ZNF484 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF484 Gene

No data available for DME Specific Peptides for ZNF484 Gene

Domains & Families for ZNF484 Gene

Gene Families for ZNF484 Gene

Protein Domains for ZNF484 Gene

Graphical View of Domain Structure for InterPro Entry

Q5JVG2

UniProtKB/Swiss-Prot:

ZN484_HUMAN :
  • Contains 1 KRAB domain.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 19 C2H2-type zinc fingers.
Domain:
  • Contains 1 KRAB domain.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 19 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF484: view

Function for ZNF484 Gene

Molecular function for ZNF484 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.
genes like me logo Genes that share phenotypes with ZNF484: view

Animal Model Products

CRISPR Products

miRNA for ZNF484 Gene

miRTarBase miRNAs that target ZNF484

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ZNF484 Gene

Localization for ZNF484 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF484 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF484 Gene COMPARTMENTS Subcellular localization image for ZNF484 gene
Compartment Confidence
nucleus 5
cytosol 3

No data available for Gene Ontology (GO) - Cellular Components for ZNF484 Gene

Pathways & Interactions for ZNF484 Gene

SuperPathways for ZNF484 Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF484: view

Pathways by source for ZNF484 Gene

2 Reactome pathways for ZNF484 Gene

Interacting Proteins for ZNF484 Gene

Gene Ontology (GO) - Biological Process for ZNF484 Gene

None

No data available for SIGNOR curated interactions for ZNF484 Gene

Drugs & Compounds for ZNF484 Gene

No Compound Related Data Available

Transcripts for ZNF484 Gene

Unigene Clusters for ZNF484 Gene

Zinc finger protein 484:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF484 Gene

ExUns: 1a · 1b · 1c · 1d · 1e · 1f ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7a · 7b · 7c · 7d · 7e
SP1: -
SP2: - - -
SP3: - - -
SP4: - - - -
SP5: - - - - - -

Relevant External Links for ZNF484 Gene

GeneLoc Exon Structure for
ZNF484
ECgene alternative splicing isoforms for
ZNF484

Expression for ZNF484 Gene

mRNA expression in normal human tissues for ZNF484 Gene

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MOPED, and MaxQB for ZNF484 Gene



SOURCE GeneReport for Unigene cluster for ZNF484 Gene Hs.668378

genes like me logo Genes that share expression patterns with ZNF484: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for ZNF484 Gene

Orthologs for ZNF484 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF484 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia ZNF484 35
  • 85.46 (n)
  • 79.21 (a)
-- 36
  • 56 (a)
ManyToMany
dog
(Canis familiaris)
Mammalia ZNF484 35
  • 86.5 (n)
  • 82.9 (a)
chimpanzee
(Pan troglodytes)
Mammalia ZNF484 35
  • 99.69 (n)
  • 99.77 (a)
ZNF484 36
  • 100 (a)
OneToOne
Species with no ortholog for ZNF484:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF484 Gene

ENSEMBL:
Gene Tree for ZNF484 (if available)
TreeFam:
Gene Tree for ZNF484 (if available)

Paralogs for ZNF484 Gene

(401) SIMAP similar genes for ZNF484 Gene using alignment to 1 proteins:

Pseudogenes.org Pseudogenes for ZNF484 Gene

genes like me logo Genes that share paralogs with ZNF484: view

Variants for ZNF484 Gene

Sequence variations from dbSNP and Humsavar for ZNF484 Gene

SNP ID Clin Chr 09 pos Sequence Context AA Info Type
rs3739602 - 92,847,282(-) GTGTG(A/G)TAAGG reference, missense
rs965654 -- 92,854,977(+) TCCCA(C/G)AAATT intron-variant
rs1022833 -- 92,864,349(+) TGGAA(C/T)GCTGA intron-variant
rs1022834 -- 92,864,448(+) AACAA(A/C)AAAAA intron-variant
rs1040978 -- 92,845,966(+) TTTTG(C/G)GGGTC utr-variant-3-prime

Structural Variations from Database of Genomic Variants (DGV) for ZNF484 Gene

Variant ID Type Subtype PubMed ID
nsv831654 CNV Gain 17160897
nsv893574 CNV Gain 21882294
esv2468145 CNV Deletion 19546169
esv2671782 CNV Deletion 23128226
esv2738775 CNV Deletion 23290073
esv1653300 CNV Deletion 17803354

Variation tolerance for ZNF484 Gene

Residual Variation Intolerance Score: 67.4% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 4.81; 66.93% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for ZNF484 Gene

Disorders for ZNF484 Gene

Relevant External Links for ZNF484

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ZNF484

No disorders were found for ZNF484 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF484 Gene

Publications for ZNF484 Gene

  1. DNA sequence and analysis of human chromosome 9. (PMID: 15164053) Humphray S.J. … Dunham I. (Nature 2004) 3 4 67
  2. Genome-wide association for abdominal subcutaneous and visceral adipose reveals a novel locus for visceral fat in women. (PMID: 22589738) Fox C.S. … Borecki I.B. (PLoS Genet. 2012) 3
  3. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3
  5. Functional proteomics mapping of a human signaling pathway. (PMID: 15231748) Colland F. … Gauthier J.M. (Genome Res. 2004) 3

Products for ZNF484 Gene

Sources for ZNF484 Gene

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