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Aliases for ZNF483 Gene

Aliases for ZNF483 Gene

  • Zinc Finger Protein 483 2 3
  • Zinc Finger Protein With KRAB And SCAN Domains 16 3 4
  • ZKSCAN16 3 4
  • Zinc Finger Protein HIT-10 3
  • KIAA1962 4
  • ZSCAN48 3

External Ids for ZNF483 Gene

Summaries for ZNF483 Gene

GeneCards Summary for ZNF483 Gene

ZNF483 (Zinc Finger Protein 483) is a Protein Coding gene. Among its related pathways are Gene Expression and Gene Expression. GO annotations related to this gene include sequence-specific DNA binding transcription factor activity. An important paralog of this gene is ZSCAN18.

UniProtKB/Swiss-Prot for ZNF483 Gene

  • May be involved in transcriptional regulation

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF483 Gene

Genomics for ZNF483 Gene

Genomic Location for ZNF483 Gene

Start:
111,525,159 bp from pter
End:
111,577,844 bp from pter
Size:
52,686 bases
Orientation:
Plus strand

Genomic View for ZNF483 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZNF483 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF483 Gene

Regulatory Elements for ZNF483 Gene

Proteins for ZNF483 Gene

  • Protein details for ZNF483 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8TF39-ZN483_HUMAN
    Recommended name:
    Zinc finger protein 483
    Protein Accession:
    Q8TF39
    Secondary Accessions:
    • Q5VZN2
    • Q8NAE1

    Protein attributes for ZNF483 Gene

    Size:
    744 amino acids
    Molecular mass:
    85098 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAB85548.1; Type=Erroneous initiation; Evidence={ECO:0000305};

    Three dimensional structures from OCA and Proteopedia for ZNF483 Gene

    Alternative splice isoforms for ZNF483 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ZNF483 Gene

Proteomics data for ZNF483 Gene at MOPED

Post-translational modifications for ZNF483 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF483 Gene

ENSEMBL proteins:
Reactome Protein details:
REFSEQ proteins:

No data available for DME Specific Peptides for ZNF483 Gene

Domains for ZNF483 Gene

Gene Families for ZNF483 Gene

HGNC:
  • ZNF :Zinc fingers, C2H2-type

UniProtKB/Swiss-Prot:

ZN483_HUMAN
Domain:
  • Contains 1 KRAB domain.:
    • Q8TF39
  • Contains 1 SCAN box domain.:
    • Q8TF39
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.:
    • Q8TF39
Similarity:
  • Contains 11 C2H2-type zinc fingers.:
    • Q8TF39
genes like me logo Genes that share domains with ZNF483: view

Function for ZNF483 Gene

Molecular function for ZNF483 Gene

UniProtKB/Swiss-Prot Function: May be involved in transcriptional regulation

Gene Ontology (GO) - Molecular Function for ZNF483 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding --
GO:0003677 DNA binding IEA --
GO:0003700 sequence-specific DNA binding transcription factor activity IBA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF483: view

miRNA for ZNF483 Gene

miRTarBase miRNAs that target ZNF483

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for ZNF483 Gene

Localization for ZNF483 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF483 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF483 Gene COMPARTMENTS Subcellular localization image for ZNF483 gene
Compartment Confidence
nucleus 4
cytosol 2

Gene Ontology (GO) - Cellular Components for ZNF483 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular --
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF483: view

Pathways for ZNF483 Gene

SuperPathways for ZNF483 Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF483: view

Pathways by source for ZNF483 Gene

2 Reactome pathways for ZNF483 Gene

Gene Ontology (GO) - Biological Process for ZNF483 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IBA --
genes like me logo Genes that share ontologies with ZNF483: view

Transcripts for ZNF483 Gene

Unigene Clusters for ZNF483 Gene

Zinc finger protein 483:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF483 Gene

No ASD Table

Relevant External Links for ZNF483 Gene

GeneLoc Exon Structure for
ZNF483
ECgene alternative splicing isoforms for
ZNF483

Expression for ZNF483 Gene

mRNA expression in normal human tissues for ZNF483 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for ZNF483 Gene

SOURCE GeneReport for Unigene cluster for ZNF483 Gene Hs.660784

genes like me logo Genes that share expressions with ZNF483: view

Orthologs for ZNF483 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZNF483 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF483 36
  • 99.82 (n)
  • 99.73 (a)
ZNF483 37
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia ZNF483 37
  • 80 (a)
OneToOne
dog
(Canis familiaris)
Mammalia ZNF483 36
  • 85.4 (n)
  • 83.33 (a)
ZNF483 37
  • 78 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Zkscan16 36
  • 70.71 (n)
  • 61 (a)
Zkscan16 16
Zkscan16 37
  • 55 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia ZNF483 37
  • 44 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Zfp483 36
  • 71.23 (n)
  • 60.11 (a)
lizard
(Anolis carolinensis)
Reptilia -- 37
  • 29 (a)
OneToMany
Species with no ortholog for ZNF483:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF483 Gene

ENSEMBL:
Gene Tree for ZNF483 (if available)
TreeFam:
Gene Tree for ZNF483 (if available)

Paralogs for ZNF483 Gene

Paralogs for ZNF483 Gene

Selected SIMAP similar genes for ZNF483 Gene using alignment to 4 proteins:

genes like me logo Genes that share paralogs with ZNF483: view

Variants for ZNF483 Gene

Sequence variations from dbSNP and Humsavar for ZNF483 Gene

SNP ID Clin Chr 09 pos Sequence Context AA Info Type MAF
rs1142970 -- 111,534,838(-) gctga(A/G)gcagg intron-variant
rs1536646 -- 111,540,396(+) ACCTC(A/G)TGGTA intron-variant
rs1969957 -- 111,539,799(+) CTATA(C/T)GATGA intron-variant
rs2418168 -- 111,537,822(+) GAGTT(C/T)TGTCA intron-variant
rs4345635 -- 111,545,114(+) TTGCC(A/G)TGTGA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF483 Gene

Variant ID Type Subtype PubMed ID
nsv893724 CNV Gain 21882294
esv2678607 CNV Deletion 23128226
esv4254 CNV Deletion 18987735
esv2738936 CNV Deletion 23290073
esv2665450 CNV Deletion 23128226
esv5602 CNV Loss 19470904

Relevant External Links for ZNF483 Gene

HapMap Linkage Disequilibrium report
ZNF483

Disorders for ZNF483 Gene

Relevant External Links for ZNF483

Genetic Association Database (GAD)
ZNF483
Human Genome Epidemiology (HuGE) Navigator
ZNF483
genes like me logo Genes that share disorders with ZNF483: view

No data available for UniProtKB/Swiss-Prot for ZNF483 Gene

Publications for ZNF483 Gene

  1. Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies. (PMID: 21102462) Elks C.E. … Murray A. (Nat. Genet. 2010) 3 49
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3 49
  4. Prediction of the coding sequences of unidentified human genes. XXII. The complete sequences of 50 new cDNA clones which code for large proteins. (PMID: 11853319) Nagase T. … Ohara O. (DNA Res. 2001) 3 4
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for ZNF483 Gene

Sources for ZNF483 Gene

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