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Aliases for ZNF48 Gene

Aliases for ZNF48 Gene

  • Zinc Finger Protein 48 2 3
  • Zinc Finger Protein 553 2 3 4
  • ZNF553 3 4
  • ZNF480 6

External Ids for ZNF48 Gene

Previous HGNC Symbols for ZNF48 Gene

  • ZNF553

Previous GeneCards Identifiers for ZNF48 Gene

  • GC16U990064
  • GC16P030315
  • GC16P030406
  • GC16P027968
  • GC16P030389

Summaries for ZNF48 Gene

GeneCards Summary for ZNF48 Gene

ZNF48 (Zinc Finger Protein 48) is a Protein Coding gene. Among its related pathways are Gene Expression and Gene Expression.

UniProtKB/Swiss-Prot for ZNF48 Gene

  • May be involved in transcriptional regulation

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF48 Gene

Genomics for ZNF48 Gene

Regulatory Elements for ZNF48 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for ZNF48 Gene

Start:
30,378,106 bp from pter
End:
30,400,108 bp from pter
Size:
22,003 bases
Orientation:
Plus strand

Genomic View for ZNF48 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ZNF48 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF48 Gene

Proteins for ZNF48 Gene

  • Protein details for ZNF48 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q96MX3-ZNF48_HUMAN
    Recommended name:
    Zinc finger protein 48
    Protein Accession:
    Q96MX3
    Secondary Accessions:
    • Q15920
    • Q4G0R3
    • Q69YP3
    • Q96IL9

    Protein attributes for ZNF48 Gene

    Size:
    618 amino acids
    Molecular mass:
    67820 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAA61316.1; Type=Frameshift; Positions=168; Evidence={ECO:0000305};

neXtProt entry for ZNF48 Gene

Proteomics data for ZNF48 Gene at MOPED

Post-translational modifications for ZNF48 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for ZNF48 Gene

Domains for ZNF48 Gene

Gene Families for ZNF48 Gene

HGNC:
  • ZNF :Zinc fingers, C2H2-type

Protein Domains for ZNF48 Gene

Suggested Antigen Peptide Sequences for ZNF48 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q96MX3

UniProtKB/Swiss-Prot:

ZNF48_HUMAN :
  • Q96MX3
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 12 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF48: view

Function for ZNF48 Gene

Molecular function for ZNF48 Gene

GENATLAS Biochemistry: zinc finger protein 48 (C2H2 type,Kruppel-like)
UniProtKB/Swiss-Prot Function: May be involved in transcriptional regulation

Gene Ontology (GO) - Molecular Function for ZNF48 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding --
GO:0003677 DNA binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with ZNF48: view
genes like me logo Genes that share phenotypes with ZNF48: view

Animal Model Products

CRISPR Products

miRNA for ZNF48 Gene

miRTarBase miRNAs that target ZNF48

No data available for Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for ZNF48 Gene

Localization for ZNF48 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF48 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF48 Gene COMPARTMENTS Subcellular localization image for ZNF48 gene
Compartment Confidence
nucleus 4
mitochondrion 1

Gene Ontology (GO) - Cellular Components for ZNF48 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with ZNF48: view

Pathways for ZNF48 Gene

SuperPathways for ZNF48 Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF48: view

Pathways by source for ZNF48 Gene

2 Reactome pathways for ZNF48 Gene

Interacting Proteins for ZNF48 Gene

Gene Ontology (GO) - Biological Process for ZNF48 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with ZNF48: view

Transcripts for ZNF48 Gene

Unigene Clusters for ZNF48 Gene

Zinc finger protein 48:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ZNF48

Primer Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF48 Gene

ExUns: 1 ^ 2 ^ 3a · 3b
SP1:
SP2:

Relevant External Links for ZNF48 Gene

GeneLoc Exon Structure for
ZNF48
ECgene alternative splicing isoforms for
ZNF48

Expression for ZNF48 Gene

mRNA expression in normal human tissues for ZNF48 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for ZNF48 Gene

SOURCE GeneReport for Unigene cluster for ZNF48 Gene Hs.513501

genes like me logo Genes that share expressions with ZNF48: view

In Situ Assay Products

No data available for mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ZNF48 Gene

Orthologs for ZNF48 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ZNF48 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ZNF48 35
  • 99.51 (n)
  • 99.51 (a)
ZNF48 36
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia ZNF48 35
  • 90.01 (n)
  • 94.17 (a)
ZNF48 36
  • 93 (a)
OneToOne
dog
(Canis familiaris)
Mammalia ZNF48 35
  • 90.76 (n)
  • 94.33 (a)
ZNF48 36
  • 93 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Zfp553 35
  • 84.39 (n)
  • 88.47 (a)
Zfp553 16
Zfp553 36
  • 87 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia ZNF48 36
  • 55 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Zfp771 35
  • 86.12 (n)
  • 89.5 (a)
Species with no ortholog for ZNF48:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF48 Gene

ENSEMBL:
Gene Tree for ZNF48 (if available)
TreeFam:
Gene Tree for ZNF48 (if available)

Paralogs for ZNF48 Gene

genes like me logo Genes that share paralogs with ZNF48: view

No data available for Paralogs for ZNF48 Gene

Variants for ZNF48 Gene

Sequence variations from dbSNP and Humsavar for ZNF48 Gene

SNP ID Clin Chr 16 pos Sequence Context AA Info Type MAF
rs3574 -- 30,400,061(-) GGGAA(C/G)CACAC utr-variant-3-prime
rs4340343 -- 30,393,163(+) cctcc(C/G)cctct intron-variant, upstream-variant-2KB
rs4788410 -- 30,385,484(+) GTTGG(A/G)TGTGG intron-variant
rs4788411 -- 30,385,494(+) GTGGC(A/G)CGTGC intron-variant
rs4788412 -- 30,394,405(+) AAGCC(C/T)GCCCA intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for ZNF48 Gene

Variant ID Type Subtype PubMed ID
nsv905724 CNV Loss 21882294
nsv827612 CNV Gain 20364138
nsv905725 CNV Loss 21882294
nsv1782 CNV Loss 18451855

Relevant External Links for ZNF48 Gene

HapMap Linkage Disequilibrium report
ZNF48

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ZNF48 Gene

Disorders for ZNF48 Gene

No disorders were found for ZNF48 Gene.

No data available for UniProtKB/Swiss-Prot for ZNF48 Gene

Publications for ZNF48 Gene

  1. Clustering of C2-H2 zinc finger motif sequences within telomeric and fragile site regions of human chromosomes. (PMID: 1505991) Lichter P. … Ward D.C. (Genomics 1992) 2 3 4
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  4. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  5. The sequence and analysis of duplication-rich human chromosome 16. (PMID: 15616553) Martin J. … Pennacchio L.A. (Nature 2004) 4

Products for ZNF48 Gene

Sources for ZNF48 Gene

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