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Aliases for ZNF479 Gene

Aliases for ZNF479 Gene

  • Zinc Finger Protein 479 2 3 5
  • Zinc Finger Protein Kr19 3 4
  • HKr19 3 4
  • KRAB Zinc Finger Protein KR19 3
  • KR19 3

External Ids for ZNF479 Gene

Previous GeneCards Identifiers for ZNF479 Gene

  • GC07M056965
  • GC07M056449
  • GC07M056998
  • GC07Mh57320
  • GC07M057191

Summaries for ZNF479 Gene

GeneCards Summary for ZNF479 Gene

ZNF479 (Zinc Finger Protein 479) is a Protein Coding gene. Among its related pathways are Gene Expression. GO annotations related to this gene include nucleic acid binding. An important paralog of this gene is ZNF718.

UniProtKB/Swiss-Prot for ZNF479 Gene

  • May be involved in transcriptional regulation.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ZNF479 Gene

Genomics for ZNF479 Gene

Regulatory Elements for ZNF479 Gene

Enhancers for ZNF479 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around ZNF479 on UCSC Golden Path with GeneCards custom track

Genomic Location for ZNF479 Gene

Chromosome:
7
Start:
57,119,574 bp from pter
End:
57,142,003 bp from pter
Size:
22,430 bases
Orientation:
Minus strand

Genomic View for ZNF479 Gene

Genes around ZNF479 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ZNF479 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ZNF479 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ZNF479 Gene

Proteins for ZNF479 Gene

  • Protein details for ZNF479 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q96JC4-ZN479_HUMAN
    Recommended name:
    Zinc finger protein 479
    Protein Accession:
    Q96JC4

    Protein attributes for ZNF479 Gene

    Size:
    524 amino acids
    Molecular mass:
    60598 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ZNF479 Gene

Proteomics data for ZNF479 Gene at MOPED

Post-translational modifications for ZNF479 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ZNF479 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ZNF479 Gene

Domains & Families for ZNF479 Gene

Gene Families for ZNF479 Gene

Protein Domains for ZNF479 Gene

Suggested Antigen Peptide Sequences for ZNF479 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q96JC4

UniProtKB/Swiss-Prot:

ZN479_HUMAN :
  • Contains 1 KRAB domain.
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
  • Contains 12 C2H2-type zinc fingers.
Domain:
  • Contains 1 KRAB domain.
Family:
  • Belongs to the krueppel C2H2-type zinc-finger protein family.
Similarity:
  • Contains 12 C2H2-type zinc fingers.
genes like me logo Genes that share domains with ZNF479: view

Function for ZNF479 Gene

Molecular function for ZNF479 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.
genes like me logo Genes that share phenotypes with ZNF479: view

Animal Model Products

CRISPR Products

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for ZNF479 Gene

Localization for ZNF479 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ZNF479 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ZNF479 Gene COMPARTMENTS Subcellular localization image for ZNF479 gene
Compartment Confidence
nucleus 5
cytosol 2

No data available for Gene Ontology (GO) - Cellular Components for ZNF479 Gene

Pathways & Interactions for ZNF479 Gene

SuperPathways for ZNF479 Gene

Superpath Contained pathways
1 Gene Expression
genes like me logo Genes that share pathways with ZNF479: view

Pathways by source for ZNF479 Gene

2 Reactome pathways for ZNF479 Gene

Interacting Proteins for ZNF479 Gene

Gene Ontology (GO) - Biological Process for ZNF479 Gene

None

No data available for SIGNOR curated interactions for ZNF479 Gene

Drugs & Compounds for ZNF479 Gene

No Compound Related Data Available

Transcripts for ZNF479 Gene

mRNA/cDNA for ZNF479 Gene

(16) REFSEQ mRNAs :
(1) Additional mRNA sequences :
(3) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ZNF479 Gene

Zinc finger protein 479:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ZNF479 Gene

No ASD Table

Relevant External Links for ZNF479 Gene

GeneLoc Exon Structure for
ZNF479
ECgene alternative splicing isoforms for
ZNF479

Expression for ZNF479 Gene

mRNA expression in normal human tissues for ZNF479 Gene

mRNA differential expression in normal tissues according to GTEx for ZNF479 Gene

This gene is overexpressed in Testis (x52.5).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for ZNF479 Gene



SOURCE GeneReport for Unigene cluster for ZNF479 Gene Hs.616660

mRNA Expression by UniProt/SwissProt for ZNF479 Gene

Q96JC4-ZN479_HUMAN
Tissue specificity: Expressed primarily in testis and fetal tissues.
genes like me logo Genes that share expression patterns with ZNF479: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues and Protein tissue co-expression partners for ZNF479 Gene

Orthologs for ZNF479 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ZNF479 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia LOC100610454 35
  • 98.69 (n)
  • 97.73 (a)
ZNF479 36
  • 98 (a)
OneToOne
cow
(Bos Taurus)
Mammalia -- 36
  • 52 (a)
OneToMany
dog
(Canis familiaris)
Mammalia -- 36
  • 37 (a)
OneToMany
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 37 (a)
ManyToMany
-- 36
  • 51 (a)
ManyToMany
mouse
(Mus musculus)
Mammalia Zfp456 36
  • 45 (a)
ManyToMany
lizard
(Anolis carolinensis)
Reptilia -- 36
  • 51 (a)
ManyToMany
-- 36
  • 32 (a)
ManyToMany
-- 36
  • 39 (a)
ManyToMany
-- 36
  • 38 (a)
ManyToMany
-- 36
  • 31 (a)
ManyToMany
-- 36
  • 31 (a)
ManyToMany
-- 36
  • 30 (a)
ManyToMany
-- 36
  • 28 (a)
ManyToMany
Species with no ortholog for ZNF479:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ZNF479 Gene

ENSEMBL:
Gene Tree for ZNF479 (if available)
TreeFam:
Gene Tree for ZNF479 (if available)

Paralogs for ZNF479 Gene

(538) SIMAP similar genes for ZNF479 Gene using alignment to 2 proteins:

Pseudogenes.org Pseudogenes for ZNF479 Gene

genes like me logo Genes that share paralogs with ZNF479: view

Variants for ZNF479 Gene

Sequence variations from dbSNP and Humsavar for ZNF479 Gene

SNP ID Clin Chr 07 pos Sequence Context AA Info Type
rs6954213 -- 57,125,036(+) attgc(C/T)cttgt intron-variant
rs12672391 -- 57,124,345(+) tcaag(G/T)ttgcc intron-variant
rs12716517 -- 57,125,437(+) TGAAG(A/G)CATAA intron-variant
rs13225770 -- 57,124,389(+) aacag(A/C)taatg intron-variant
rs13225992 -- 57,126,932(+) ATACT(A/G)CTGTA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ZNF479 Gene

Variant ID Type Subtype PubMed ID
esv2752160 CNV Gain 17911159
esv2734468 CNV Deletion 23290073
nsv888071 CNV Gain 21882294
esv2734476 CNV Deletion 23290073

Variation tolerance for ZNF479 Gene

Residual Variation Intolerance Score: 96.9% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.96; 49.46% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for ZNF479 Gene

Disorders for ZNF479 Gene

Relevant External Links for ZNF479

Human Genome Epidemiology (HuGE) Navigator
ZNF479
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ZNF479

No disorders were found for ZNF479 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ZNF479 Gene

Publications for ZNF479 Gene

  1. Molecular cloning and preliminary functional analysis of two novel human KRAB zinc finger proteins, HKr18 and HKr19. (PMID: 11410164) Mark C. … Hellman L. (DNA Cell Biol. 2001) 2 3 4 67

Products for ZNF479 Gene

Sources for ZNF479 Gene

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